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Journal of Experimental Botany, ISSN 0022-0957, 1/2012, Volume 63, Issue 8, pp. 3207 - 3218
Changes in pH are now widely accepted as a signalling mechanism in cells. In plants, proton pumps in the plasma membrane and tonoplast play a key role in... 
Mesophyll cells | Adhesives | Perfusion | Imaging | Plant roots | Sensors | Plants | Calibration | Cytosol | RESEARCH PAPER | GFP | Auxin | PHusion | Arabidopsis | ATPase | pH homeostasis | Apoplast | Cytoplasm | Sensor | auxin | INTRACELLULAR PH | ROOT-TIPS | pHusion | STOMATAL CLOSURE | PLANT SCIENCES | cytoplasm | GREEN FLUORESCENT PROTEIN | CYTOSOLIC CA2 | ALGAE | H+ BUFFERS | H+-ATPase | sensor | ABSCISIC-ACID | LIVING CELLS | Organ Specificity - drug effects | Gene Expression - drug effects | Cytosol - drug effects | Extracellular Space - drug effects | Imaging, Three-Dimensional - methods | Plant Roots - drug effects | Extracellular Space - metabolism | Hydrogen-Ion Concentration - drug effects | Cell Membrane - metabolism | Mesophyll Cells - drug effects | Mesophyll Cells - metabolism | Homeostasis - drug effects | Cell Membrane - drug effects | Mesophyll Cells - cytology | Alkalies | Cell Survival - drug effects | Arabidopsis - drug effects | Intracellular Space - drug effects | Plant Roots - metabolism | Seedlings - cytology | Arabidopsis - cytology | Adhesives - pharmacology | Genes, Reporter - genetics | Plant Roots - cytology | Seedlings - drug effects | Arabidopsis - metabolism | Indoleacetic Acids - pharmacology | Intracellular Space - metabolism | Biosensing Techniques - methods | Cytosol - metabolism | Index Medicus | Research Papers
Journal Article
Plant Physiology, ISSN 0032-0889, 7/2012, Volume 159, Issue 3, pp. 1159 - 1175
In the interaction between Arabidopsis (Arabidopsis thaliana) and the generalist herbivorous insect Spodoptera littoralis, little is known about early events... 
Leaves | Insect larvae | Calcium | Plant growth regulators | Genes | Gene expression regulation | Trichomes | Plants | Herbivores | Phytophagous insects | PLANTS INTERACTING WITH OTHER ORGANISMS | MOLECULAR-PATTERNS | DEFENSE RESPONSES | LIMA-BEAN LEAVES | METHYL JASMONATE | ORAL SECRETIONS | INDUCED RESISTANCE | GLUCOSINOLATE ACCUMULATION | AGROBACTERIUM-MEDIATED TRANSFORMATION | CALMODULIN-LIKE PROTEIN | ABSCISIC-ACID | PLANT SCIENCES | Arabidopsis - physiology | Intracellular Calcium-Sensing Proteins - genetics | Calcium - metabolism | Herbivory - physiology | Cytosol - drug effects | Glucosinolates - metabolism | Protein Transport - drug effects | RNA, Messenger - metabolism | Arabidopsis Proteins - metabolism | Cell Nucleus - metabolism | Spodoptera - drug effects | Stress, Physiological - drug effects | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Spodoptera - physiology | Subcellular Fractions - drug effects | RNA, Messenger - genetics | Signal Transduction - genetics | Cyclopentanes - pharmacology | Intracellular Calcium-Sensing Proteins - metabolism | Mutation - genetics | Herbivory - drug effects | Subcellular Fractions - metabolism | Arabidopsis - genetics | Oxylipins - metabolism | Gene Expression Regulation, Plant - drug effects | Animals | Signal Transduction - drug effects | Calcium Signaling - drug effects | Oxylipins - pharmacology | Arabidopsis - parasitology | Cyclopentanes - metabolism | Cytosol - metabolism | Cell Nucleus - drug effects | Arabidopsis thaliana | Arabidopsis | Plant genetics | Genetic aspects | Instrument industry | Chemical properties | Gene expression | Index Medicus
Journal Article
Molecular Nutrition and Food Research, ISSN 1613-4125, 07/2011, Volume 55, Issue 7, pp. 999 - 1009
Scope: Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables such as broccoli. The ability of SFN to inhibit histone deacetylase (HDAC)... 
Epigenetics | Isothiocyanate | Prostate cancer | Chemoprevention | Apoptosis | SUBEROYLANILIDE HYDROXAMIC ACID | ACETYLATION | FOOD SCIENCE & TECHNOLOGY | THERAPY | PATHWAY | EPIDEMIOLOGIC EVIDENCE | IN-VIVO | GROWTH | DEGRADATION | INHIBITORS | EXPRESSION | Thiocyanates - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - drug effects | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Cytosol - drug effects | Male | NAD(P)H Dehydrogenase (Quinone) - genetics | Promoter Regions, Genetic - drug effects | Tubulin - drug effects | Prostate - pathology | Tubulin - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Prostate - drug effects | Thiocyanates - pharmacology | Hyperplasia - drug therapy | Anticarcinogenic Agents - pharmacology | Isothiocyanates | Prostatic Neoplasms - drug therapy | Cell Line | Prostatic Neoplasms - pathology | Histone Deacetylase 6 | Epithelial Cells - pathology | Histone Deacetylases - metabolism | Hyperplasia - pathology | Acetylation - drug effects | NAD(P)H Dehydrogenase (Quinone) - drug effects | Prostate - cytology | Cell Line, Tumor | Cytosol - metabolism | Histone Deacetylase Inhibitors - pharmacology | Histone Deacetylases - drug effects | Histone Deacetylase 2 - metabolism | Histones - metabolism | Cell Cycle - drug effects | Index Medicus | apoptosis | isothiocyanate | prostate cancer | chemoprevention | epigenetics
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e87915 - e87915
Neuroimmune gene induction is involved in many brain pathologies including addiction. Although increased expression of proinflammatory cytokines has been found... 
INDUCED NEUROINFLAMMATION | SLICE CULTURES | CELLS | CHROMATIN PROTEIN HMGB1 | MULTIDISCIPLINARY SCIENCES | MOBILITY GROUP BOX-1 | SPINAL-CORD | INDUCTION | ALCOHOL-DRINKING | NF-KAPPA-B | RECEPTOR 4 | Microglia - metabolism | Entorhinal Cortex - metabolism | Humans | Cytosol - drug effects | Hippocampus - drug effects | Brain - metabolism | Naltrexone - pharmacology | Cell Nucleus - metabolism | HMGB1 Protein - metabolism | Inflammation Mediators - metabolism | Benzamides - pharmacology | Neurons - metabolism | Toll-Like Receptor 4 - antagonists & inhibitors | Neurons - drug effects | Hydroxamic Acids - pharmacology | Cytokines - metabolism | Microglia - drug effects | Rats | Histone Deacetylases - metabolism | Entorhinal Cortex - drug effects | Toll-Like Receptor 4 - metabolism | Blotting, Western | Brain - drug effects | Gene Expression Regulation - drug effects | Hippocampus - metabolism | Acetylation - drug effects | Ethanol - pharmacology | Animals | Signal Transduction - drug effects | Models, Biological | Cytosol - metabolism | Histone Deacetylase Inhibitors - pharmacology | Mice | Pyridines - pharmacology | Cell Nucleus - drug effects | Brain - immunology | Brain research | Alcohol, Denatured | Chromosomal proteins | Cytokines | RNA | Neurons | Analysis | Alcohol | Brain | Drug abuse | Histone deacetylase | Neurosciences | Spinal cord | Brain slice preparation | Neurobiology | Biology | Activation | Kinases | Experiments | HMGB1 protein | Proteins | Neurodegeneration | Toll-like receptors | Translocation | Glycyrrhizin | Ethanol | Alcoholism | Cultures | Hazards | Inflammation | TLR4 protein | Tumor necrosis factor-α | IL-1β | Gene expression | Addictions | Immune systems | Studies | Cortex (entorhinal) | Signaling | Hypotheses | Inhibitors | Addiction | Ligands | Laboratory animals | Hippocampus | Apoptosis | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 2/2010, Volume 188, Issue 4, pp. 547 - 563
Journal Article
The Plant Cell, ISSN 1040-4651, 8/2013, Volume 25, Issue 8, pp. 2970 - 2985
Fertilization in flowering plants requires the temporal and spatial coordination of many developmental processes, including pollen production, anther... 
Endocytosis | RESEARCH ARTICLES | Pollen tubes | Antibodies | Tyrphostins | Anthers | Auxins | Pollen | Plants | Transgenic plants | Plant cells | CLATHRIN-MEDIATED ENDOCYTOSIS | MALE GAMETOPHYTE | COATED VESICLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT-CELLS | TRAFFICKING | PLASMA-MEMBRANE | PLANT SCIENCES | CELL BIOLOGY | GOLGI NETWORK | VACUOLAR SORTING RECEPTOR | IN-VIVO | FM-DYES | Pollen - metabolism | Arabidopsis - growth & development | Cytosol - drug effects | Pollen Tube - metabolism | Protein Transport - drug effects | Arabidopsis Proteins - metabolism | Adaptor Protein Complex 2 - metabolism | Seeds - growth & development | Fertilization - drug effects | Protein Binding - drug effects | Cell Membrane - metabolism | Cell Membrane - drug effects | Germination - drug effects | Pollen - cytology | Pollen - drug effects | Pollen - growth & development | Green Fluorescent Proteins - metabolism | Arabidopsis - drug effects | Seeds - metabolism | Seeds - drug effects | Arabidopsis - cytology | Endocytosis - drug effects | Mutation - genetics | Clathrin - metabolism | Arabidopsis - metabolism | Indoleacetic Acids - pharmacology | Cytosol - metabolism | Pollen Tube - drug effects | Pollen Tube - growth & development | Plant proteins | Arabidopsis thaliana | Growth | Physiological aspects | Development | Research | Index Medicus
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 08/2012, Volume 32, Issue 34, pp. 11820 - 11834
In Alzheimer disease (AD), the perturbation of the endoplasmic reticulum (ER) calcium (Ca2+) homeostasis has been linked to presenilins, the catalytic core in... 
DANTROLENE | PRESENILINS | INFLUX | CA2+ RELEASE | CALCIUM-RELEASE | INCREASES | CHANNELS | PRECURSOR PROTEIN | N-TERMINUS | NEUROSCIENCES | I-CRAC | Amyloid Precursor Protein Secretases - genetics | Calcium - metabolism | Embryo, Mammalian | Humans | Calcium Channel Blockers - therapeutic use | Memory Disorders - metabolism | Aminophenols - therapeutic use | RNA, Messenger - metabolism | Phosphorylation - genetics | Endoplasmic Reticulum - drug effects | Muscle Relaxants, Central - pharmacology | Amyloid beta-Peptides - metabolism | Exploratory Behavior - drug effects | Caffeine - pharmacology | Purines - therapeutic use | Phosphorylation - drug effects | Disease Models, Animal | Membrane Potentials - drug effects | Mice, Transgenic | Dantrolene - pharmacology | Mutation - genetics | Enzyme Inhibitors - therapeutic use | Amyloid Precursor Protein Secretases - metabolism | Patch-Clamp Techniques | Memory Disorders - etiology | Analysis of Variance | Ryanodine Receptor Calcium Release Channel - genetics | Cytosol - metabolism | Plaque, Amyloid - metabolism | Mice | Inositol 1,4,5-Trisphosphate Receptors - genetics | Membrane Potentials - genetics | Alzheimer Disease - complications | Cytosol - drug effects | Endoplasmic Reticulum - metabolism | Ryanodine Receptor Calcium Release Channel - metabolism | Endoplasmic Reticulum - pathology | Maleimides - therapeutic use | Transfection | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Reaction Time - drug effects | Amyloid beta-Protein Precursor - metabolism | Neurons - physiology | Membrane Proteins - metabolism | Neurons - drug effects | Neuroblastoma - pathology | Brain - cytology | Peptide Fragments - metabolism | Plaque, Amyloid - pathology | Gene Expression Regulation - genetics | Cells, Cultured | Maze Learning - drug effects | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Memory Disorders - drug therapy | Recognition (Psychology) - drug effects | Alzheimer Disease - metabolism | Alzheimer Disease - genetics | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e89351 - e89351
Although the anti-cancer effects of curcumin has been shown in various cancer cell types, in vitro, pre-clinical and clinical studies showed only a limited... 
OVARIAN-CANCER CELLS | BREAST-CANCER | APOPTOSIS | OXIDATIVE STRESS | SIGNALING PATHWAYS | PROTEIN | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SUPPRESSES PROLIFERATION | STAT3 PHOSPHORYLATION | BNIP3 GENE | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Curcumin - chemistry | Humans | Cytosol - drug effects | Biological Availability | Curcumin - metabolism | Membrane Potential, Mitochondrial - drug effects | Antineoplastic Agents - metabolism | Biological Transport | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Proto-Oncogene Proteins c-akt - metabolism | STAT3 Transcription Factor - metabolism | Membrane Proteins - genetics | Curcumin - pharmacokinetics | Curcumin - pharmacology | Proto-Oncogene Proteins - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Antineoplastic Agents - chemistry | MAP Kinase Signaling System - drug effects | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Cytosol - metabolism | Care and treatment | Research | Oncology, Experimental | Analysis | Cancer | Drugs | Phosphorylation | Toxicity | Epithelial cells | Cytotoxicity | AKT protein | Drug delivery | Kinases | Tissues | Anticancer properties | Lipophilic | Mitochondria | Rodents | DNA methylation | Curcumin | Membrane potential | Mammary gland | Stat3 protein | Extracellular signal-regulated kinase | Breast cancer | Bioavailability | BNIP3 protein | Tagging | Epigenetics | Conjugation | Apoptosis | Index Medicus
Journal Article