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Nature (London), ISSN 1476-4687, 2016, Volume 532, Issue 7598, pp. 255 - 258
Journal Article
Nature (London), ISSN 1476-4687, 2019, Volume 567, Issue 7747, pp. 262 - 266
Cyclic GMP-AMP (cGAMP) synthase (cGAS) detects infections or tissue damage by binding to microbial or self DNA in the cytoplasm(1). Upon binding DNA, cGAS... 
SYNTHASE | CYCLIC GMP-AMP | MAVS | PROTEIN | ROLES | MULTIDISCIPLINARY SCIENCES | ADAPTER | SENSOR | Nucleotides, Cyclic - metabolism | Interferons - biosynthesis | Beclin-1 - deficiency | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Autophagy-Related Protein 5 - genetics | Autophagy-Related Protein-1 Homolog - metabolism | DNA Viruses - metabolism | Interferons - immunology | Autophagy | DNA Viruses - genetics | Sea Anemones | Membrane Proteins - deficiency | HEK293 Cells | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Phosphate-Binding Proteins | Signal Transduction | Membrane Proteins - genetics | DNA, Viral - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Autophagosomes - metabolism | Cytosol - virology | Protein Transport | Carrier Proteins - genetics | Animals | Autophagy-Related Protein-1 Homolog - deficiency | Carrier Proteins - metabolism | Monomeric GTP-Binding Proteins - metabolism | Autophagy-Related Protein 5 - deficiency | Autophagy-Related Protein 5 - metabolism | Beclin-1 - genetics | Golgi Apparatus - metabolism | Mice | Beclin-1 - metabolism | Autophagy-Related Protein-1 Homolog - genetics | Nucleotides, Cyclic - immunology | Evolution, Molecular | Biological research | Autophagy (Cytology) | Enzymes | Physiological aspects | Interferon | Research | Cytoplasm | Biology, Experimental | G proteins | Biological response modifiers | Health aspects | Protein binding
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 510, Issue 7504, pp. 298 - 302
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 330, Issue 6008, pp. 1247 - 1251
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 4, p. e34653
Background: Shedding microvesicles are membrane released vesicles derived directly from the plasma membrane. Exosomes are released membrane vesicles of late... 
ACTIVATION | FUSION | EPITHELIAL-CELLS | MEMBRANE-VESICLES | MULTIDISCIPLINARY SCIENCES | EXOSOMES | SPERMATOZOA | EXTRACELLULAR ORGANELLES PROSTASOMES | ADENOSINE-TRIPHOSPHATASE | SECRETION | ASSOCIATION | Exosomes - metabolism | Cell Line | NIH 3T3 Cells | Microscopy, Electron, Transmission - methods | Secretory Vesicles - metabolism | DNA - metabolism | RNA, Messenger - metabolism | Clathrin - metabolism | Animals | Cell Nucleus - metabolism | Biological Transport | Myocytes, Cardiac - metabolism | Cytosol - metabolism | Cell Membrane - metabolism | Membrane Proteins - metabolism | Mice | Annexin A2 - metabolism | Caveolin 3 - metabolism | Fibroblasts - metabolism | RNA - metabolism | Clathrin | RNA | Genes | Hostages | Nucleotide sequencing | Gene expression | DNA sequencing | Heart | Flow cytometry | Sperm | Centrifugation | Lung cancer | Ultracentrifugation | Biochemistry | Exosomes | Cytosol | Nuclei | Muscular dystrophy | Gene sequencing | Vesicles | Rodents | Penicillin | Fibroblasts | Public health | Deoxyribonucleic acid--DNA | Messages | Nucleotide sequence | Caveolin | Membrane vesicles | Cardiomyocytes | Electron microscopy | Metabolism | Ribonucleic acid--RNA | Medicine | Polymerase | DNA nucleotidylexotransferase | Cytometry | Hospitals | Transmission electron microscopy | MicroRNAs | Media (differential) | Biochemical characteristics | Clinical medicine | Mutation | Prostate | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Molecular cell, ISSN 1097-2765, 2018, Volume 69, Issue 4, pp. 581 - 593.e7
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7690, pp. 128 - 132
.... This in part reflects the need for mitochondria to generate one-carbon units and export them to the cytosol for anabolic metabolism(2,9... 
CHAIN | HYPERTROPHIC CARDIOMYOPATHY | SERINE HYDROXYMETHYLTRANSFERASE | METABOLISM | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | DEFECT | LACTIC-ACIDOSIS | MUTATIONS | IDENTIFICATION | ANTICODON WOBBLE NUCLEOTIDE | Mitochondria - enzymology | Electron Transport | Protein Biosynthesis | Humans | Ribosomes - metabolism | Sarcosine - metabolism | Multifunctional Enzymes - metabolism | Thymine Nucleotides - biosynthesis | Oxidative Phosphorylation - drug effects | Glycine Hydroxymethyltransferase - deficiency | HEK293 Cells | RNA, Transfer - genetics | Codon - genetics | RNA, Transfer - chemistry | Leucine - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Biocatalysis | RNA, Transfer - metabolism | HCT116 Cells | Mitochondria - metabolism | Mitochondria - drug effects | Glycine Hydroxymethyltransferase - metabolism | Guanosine - metabolism | Tetrahydrofolates - metabolism | Lysine - genetics | Carrier Proteins - metabolism | Methylation - drug effects | Folic Acid - metabolism | Aminohydrolases - metabolism | Folic Acid Antagonists - pharmacology | GTP-Binding Proteins - metabolism | Mitochondria | Physiological aspects | Genetic aspects | Methylation | Observations | Genetic translation | Folic acid | Transfer RNA | Phosphorylation | Inborn errors of metabolism | Peptides | Serine | Biosynthesis | Mitochondrial DNA | Thymidine | Catalytic activity | Leucine | Cytosol | Experiments | Anticancer properties | Proteins | Purines | Antitumor agents | Metabolites | Lymphocytes | Vitamin B | Catalysis | Enzymes | Translation | tRNA Ala | tRNA | Methionine | Metabolism | Carbon | Immunosuppression | Oxidative phosphorylation | Lysine | Proteomics | Electron transport | Respiration | Codons | Cancer
Journal Article
The FEBS journal, ISSN 1742-464X, 2010, Volume 277, Issue 14, pp. 3051 - 3067
... of investigation support the view that increasing levels of amyloid‐β 1–42 (Aβ), the proteolytic product of amyloid precursor protein (APP) metabolism, might be centrally... 
amyloid | PSD95 | Shank | Alzheimer’s disease | oligomers | Alzheimer's disease | BIOCHEMISTRY & MOLECULAR BIOLOGY | COGNITIVE IMPAIRMENT | DELETION SYNDROME | DENDRITIC SPINES | GLUTAMATE RECEPTORS | POSTSYNAPTIC DENSITY PROTEINS | SOLUBLE BETA-AMYLOID(1-40) | A-BETA | LONG-TERM POTENTIATION | NMDA RECEPTOR SUBUNITS | SECRETED OLIGOMERS | Disks Large Homolog 4 Protein | Amyloid beta-Peptides - pharmacology | Humans | Cerebral Cortex - pathology | Male | Dendritic Spines - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Cerebral Cortex - metabolism | Alzheimer Disease - pathology | Alzheimer Disease - diagnosis | Brain - metabolism | Dementia - metabolism | Synapses - metabolism | Protein Multimerization - physiology | Amyloid beta-Peptides - metabolism | Aged, 80 and over | Female | Mice, Inbred DBA | Cell Membrane - metabolism | Membrane Proteins - metabolism | Neurons - metabolism | Neurons - drug effects | Peptide Fragments - genetics | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Nerve Tissue Proteins - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Carrier Proteins - metabolism | Guanylate Kinases | Qa-SNARE Proteins - metabolism | Alzheimer Disease - metabolism | Brain - pathology | Cytosol - metabolism | Aged | Mice | Synaptosomal-Associated Protein 25 - metabolism | Vesicle-Associated Membrane Protein 2 - metabolism | Protein Binding - physiology | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2007, Volume 282, Issue 26, pp. 18810 - 18818
Journal Article