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Cell, ISSN 0092-8674, 2007, Volume 129, Issue 7, pp. 1287 - 1298
and are considered to be prototypical intracellular pathogens that have evolved strategies to enable growth in the intracellular phagosomes. In contrast, we... 
CELLBIO | HUMDISEASE | MICROBIO | HOST-CELLS | II MOLECULES | DENDRITIC CELLS | BOVIS BCG | PHAGOSOMAL MEMBRANES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALVEOLAR MACROPHAGES | INFECTION | VIRULENCE | CALMETTE-GUERIN | CROSS-PRESENTATION | CELL BIOLOGY | Immunohistochemistry | Cell Proliferation | Intracellular Membranes - physiology | Humans | Myeloid Cells - physiology | Phagosomes - physiology | Myeloid Cells - ultrastructure | Lysosomes - physiology | Cell Movement - physiology | Intracellular Membranes - ultrastructure | Mycobacterium tuberculosis - physiology | Mycobacterium - ultrastructure | Phagosomes - ultrastructure | Membrane Proteins - metabolism | Mycobacterium leprae - physiology | Biomarkers - metabolism | Mycobacterium leprae - ultrastructure | Microscopy, Electron, Transmission | Host-Parasite Interactions - physiology | Mycobacterium - physiology | Cells, Cultured | Cytosol - ultrastructure | Mycobacterium tuberculosis - ultrastructure | Mycobacterium leprae - genetics | Gene Expression Regulation, Bacterial - physiology | Mycobacterium - genetics | Cell Compartmentation - physiology | Cell Division - physiology | Lysosomes - ultrastructure | Cell Death - physiology | Cytosol - physiology | Antigen Presentation - physiology | Myeloid Cells - microbiology | Mycobacterium tuberculosis - genetics | Tuberculosis | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. 525 - 528
The peptide-loading complex (PLC) is a transient, multisubunit membrane complex in the endoplasmic reticulum that is essential for establishing a hierarchical... 
TAP | TRANSPORTER | PARTICLE ELECTRON CRYOMICROSCOPY | TAPASIN | MULTIDISCIPLINARY SCIENCES | MOLECULAR ARCHITECTURE | ERP57 | EM STRUCTURE DETERMINATION | CALRETICULIN P-DOMAIN | MAJOR HISTOCOMPATIBILITY COMPLEX | BINDING | ATP Binding Cassette Transporter, Subfamily B, Member 2 - chemistry | Protein Disulfide-Isomerases - metabolism | Protein Disulfide-Isomerases - ultrastructure | ATP Binding Cassette Transporter, Subfamily B, Member 3 - chemistry | Cytosol - immunology | Humans | Endoplasmic Reticulum - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 2 - ultrastructure | Histocompatibility Antigens Class I - metabolism | Multiprotein Complexes - metabolism | Endoplasmic Reticulum - chemistry | Antigen Presentation | ATP Binding Cassette Transporter, Subfamily B, Member 3 - ultrastructure | Calreticulin - metabolism | Protein Domains | Membrane Transport Proteins - metabolism | Binding Sites | Histocompatibility Antigens Class I - immunology | Models, Molecular | Histocompatibility Antigens Class I - chemistry | Burkitt Lymphoma - chemistry | Disease Progression | Membrane Transport Proteins - chemistry | Calreticulin - chemistry | Calreticulin - ultrastructure | Cryoelectron Microscopy | Multiprotein Complexes - ultrastructure | Multiprotein Complexes - chemistry | ATP Binding Cassette Transporter, Subfamily B, Member 3 - metabolism | Histocompatibility Antigens Class I - ultrastructure | Membrane Transport Proteins - ultrastructure | Models, Biological | ATP Binding Cassette Transporter, Subfamily B, Member 2 - metabolism | Cytosol - metabolism | Protein Disulfide-Isomerases - chemistry | Multiprotein Complexes - immunology | Peptides | Physiological aspects | Major histocompatibility complex | Oxidoreductase | Antigen processing | Lymphocytes T | Cell surface | Proteins | Calreticulin | Binding | Symbiosis | Translocation | Antigens | Immune response | Macromolecules | TAP protein | Lymphoma | Glycan | Burkitt's lymphoma | Immune systems | Tapasin | Microscopy | Lymphomas | Endoplasmic reticulum | Histocompatibility | ABC transporter | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2003, Volume 23, Issue 18, pp. 7183 - 7193
Journal Article
Autophagy, ISSN 1554-8627, 09/2015, Volume 11, Issue 9, pp. 1561 - 1579
Plasmodium parasites are transmitted by Anopheles mosquitoes to the mammalian host and actively infect hepatocytes after passive transport in the bloodstream... 
long-term live imaging | cytosolic immune response | selective autophagy | Plasmodium liver-stage | malaria | LC3 | ubiquitin | Cytosolic immune response | Ubiquitin | Malaria | Long-term live imaging | Selective autophagy | STAGE DEVELOPMENT | BACTERIA | RECOGNITION | BERGHEI | AUTOPHAGY | MATURATION | CELL BIOLOGY | MALARIA PARASITE | PROTEINS | CELL | Vacuoles - ultrastructure | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Cytosol - immunology | Humans | Virulence | Ubiquitin - metabolism | Autophagy | Immunity | Hepatocytes - parasitology | Intracellular Membranes - ultrastructure | Life Cycle Stages | Ubiquitination | Lysosomes - metabolism | Time Factors | Parasites - pathogenicity | Parasites - immunology | Imaging, Three-Dimensional | Parasites - growth & development | Plasmodium berghei - pathogenicity | Biomarkers - metabolism | Heat-Shock Proteins - metabolism | Malaria - immunology | Hepatocytes - immunology | Sporozoites - ultrastructure | Hep G2 Cells | Lysosomes - ultrastructure | Animals | Immune Evasion | Malaria - parasitology | Survival Analysis | Hepatocytes - ultrastructure | Plasmodium berghei - growth & development | Plasmodium berghei - ultrastructure | Vacuoles - metabolism | Sporozoites - physiology | Mice | Liver - parasitology | Adaptor Proteins, Signal Transducing - metabolism | Parasites - ultrastructure | Galectins - metabolism | Intracellular Membranes - metabolism | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2015, Volume 35, Issue 14, pp. 5724 - 5742
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1152 - 11
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 07/2015, Volume 1853, Issue 7, pp. 1646 - 1657
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 118 - 128
Dioscin, a natural steroid saponin, has been widely investigated. However, its anti-cancer activities on human lung cancer cells are still unknown. In the... 
Dioscin | Human lung cancer cell lines | Anti-cancer | Mitochondrial pathway | DNA damage | APOPTOSIS | PROTEIN | FOOD SCIENCE & TECHNOLOGY | SOLANUM STEROIDAL GLYCOSIDES | HL-60 CELLS | DEATH | FAMILY | CYTOCHROME-C | BCL-2 | SAPONINS | LIVER-DAMAGE | TOXICOLOGY | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Adenocarcinoma - ultrastructure | Adenocarcinoma of Lung | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Cytosol - drug effects | Protein Transport - drug effects | Mitochondria - ultrastructure | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | Adenocarcinoma - metabolism | Inhibitory Concentration 50 | Cell Survival - drug effects | Diosgenin - analogs & derivatives | Microscopy, Electron, Transmission | Small Cell Lung Carcinoma - ultrastructure | Carcinoma, Large Cell - metabolism | Diosgenin - pharmacology | Carcinoma, Large Cell - ultrastructure | Cytosol - ultrastructure | Mitochondria - metabolism | Mitochondria - drug effects | Adenocarcinoma - drug therapy | Apoptosis Regulatory Proteins - metabolism | Signal Transduction - drug effects | Apoptosis Regulatory Proteins - antagonists & inhibitors | Lung Neoplasms - ultrastructure | Apoptosis Regulatory Proteins - agonists | Cell Line, Tumor | Cytosol - metabolism | Cell Proliferation - drug effects | S Phase - drug effects | DNA Damage | Antineoplastic Agents, Phytogenic - pharmacology | Care and treatment | Genetic aspects | Lung cancer | DNA | Cancer | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, pp. e0159582 - e0159582
Increasing evidence suggests that metal dyshomeostasis plays an important role in human neurodegenerative diseases. Although distinctive metal distributions... 
NERVOUS-SYSTEM | SYNAPTIC VESICLES | IRON-METABOLISM | CORTICAL-NEURONS | PLASMA-MASS SPECTROMETRY | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | DOPAMINERGIC-NEURONS | SUBSTANTIA-NIGRA | NEURODEGENERATIVE DISEASES | ZINC | Calcium - metabolism | Embryo, Mammalian | Zinc - metabolism | Endoplasmic Reticulum - metabolism | Calcium - analysis | Mitochondria - ultrastructure | Cerebral Cortex - metabolism | Endoplasmic Reticulum - ultrastructure | Freezing | Cerebral Cortex - ultrastructure | Iron - analysis | Manganese - analysis | Cell Nucleus - metabolism | Neurons - ultrastructure | Zinc - analysis | Synchrotrons | Spectrometry, X-Ray Emission | Copper - metabolism | CA1 Region, Hippocampal - metabolism | Neurons - metabolism | CA1 Region, Hippocampal - ultrastructure | Dentate Gyrus - metabolism | Rats | Mitochondria - metabolism | Cell Nucleus - ultrastructure | Iron - metabolism | Animals | Copper - analysis | Manganese - metabolism | Primary Cell Culture | Dentate Gyrus - ultrastructure | Measurement | Usage | Metals | Brain cells | Degassing of metals | Nervous system | Degeneration | Research | X-ray spectroscopy | Risk factors | Brain | Neurosciences | Calcium | Laboratories | Metal concentrations | Neurobiology | Spatial discrimination | Fluorescence | Iron | Cytosol | Accumulation | Mitochondria | Rodents | Aging | Synchrotron radiation | Neurodegenerative diseases | Neurons | Silicon nitride | Metabolism | Nitrogen | Organelles | Embryos | Zinc | Heavy metals | Neurological diseases | Dentate gyrus | Brain research | Spatial distribution | X-ray fluorescence | X radiation | Intracellular | Alzheimers disease | Endoplasmic reticulum | Hippocampus | Manganese | Index Medicus | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | MATERIALS SCIENCE
Journal Article