Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3610) 3610
Publication (178) 178
Book Review (149) 149
Book Chapter (25) 25
Conference Proceeding (4) 4
Book / eBook (2) 2
Dissertation (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (3433) 3433
animals (2450) 2450
cytosol - metabolism (1770) 1770
rats (1218) 1218
humans (1079) 1079
male (919) 919
cytosol - enzymology (766) 766
female (651) 651
cell biology (647) 647
biochemistry & molecular biology (640) 640
cytosol (612) 612
liver - ultrastructure (482) 482
proteins (455) 455
mice (442) 442
microscopy, electron (425) 425
kinetics (412) 412
calcium - metabolism (403) 403
cytosol - ultrastructure (386) 386
cells (348) 348
cells, cultured (314) 314
cell nucleus - metabolism (307) 307
research (292) 292
cytosol - chemistry (271) 271
cell line (270) 270
cytosol - drug effects (260) 260
mitochondria - metabolism (256) 256
mitochondria (253) 253
in vitro techniques (245) 245
liver - metabolism (241) 241
molecular sequence data (235) 235
physiological aspects (228) 228
rats, inbred strains (228) 228
time factors (219) 219
cell membrane - metabolism (217) 217
amino acid sequence (211) 211
liver - enzymology (203) 203
neurosciences (195) 195
molecular weight (191) 191
apoptosis (187) 187
multidisciplinary sciences (185) 185
phosphorylation (185) 185
calcium (184) 184
abridged index medicus (181) 181
cellular biology (180) 180
membrane proteins - metabolism (176) 176
cell membrane - ultrastructure (173) 173
rats, sprague-dawley (171) 171
protein binding (170) 170
expression (167) 167
cell fractionation (165) 165
rats, wistar (162) 162
analysis (161) 161
enzymes (160) 160
protein (160) 160
antibodies (159) 159
plant sciences (159) 159
rabbits (157) 157
hydrogen-ion concentration (156) 156
biological transport (155) 155
mitochondria - ultrastructure (155) 155
immunohistochemistry (154) 154
cattle (150) 150
physiology (145) 145
endoplasmic-reticulum (144) 144
blotting, western (140) 140
liver (139) 139
cell nucleus - ultrastructure (138) 138
cytosol - physiology (138) 138
endoplasmic reticulum - metabolism (138) 138
models, biological (138) 138
endocrinology & metabolism (136) 136
hela cells (136) 136
biochemistry (135) 135
cell membranes (134) 134
cytosol - analysis (132) 132
biophysics (130) 130
activation (129) 129
article (129) 129
biology (129) 129
membranes (129) 129
adenosine triphosphate - metabolism (125) 125
carrier proteins - metabolism (125) 125
pharmacology & pharmacy (125) 125
mitochondria - enzymology (123) 123
intracellular membranes - metabolism (120) 120
centrifugation, density gradient (119) 119
electrophoresis, polyacrylamide gel (118) 118
identification (118) 118
binding (115) 115
protein transport (115) 115
brain - ultrastructure (114) 114
cell membrane - enzymology (114) 114
metabolism (114) 114
microscopy, fluorescence (113) 113
localization (112) 112
signal transduction (112) 112
binding sites (111) 111
research article (111) 111
endocytosis (109) 109
transport (109) 109
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3501) 3501
Russian (53) 53
French (17) 17
Polish (17) 17
German (16) 16
Japanese (4) 4
Chinese (3) 3
Spanish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
by van der Wel, Nicole and Hava, David and Houben, Diane and Fluitsma, Donna and van Zon, Maaike and Pierson, Jason and Brenner, Michael and Peters, Peter J
Cell, ISSN 0092-8674, 2007, Volume 129, Issue 7, pp. 1287 - 1298
and are considered to be prototypical intracellular pathogens that have evolved strategies to enable growth in the intracellular phagosomes. In contrast, we... 
CELLBIO | HUMDISEASE | MICROBIO | HOST-CELLS | II MOLECULES | DENDRITIC CELLS | BOVIS BCG | PHAGOSOMAL MEMBRANES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALVEOLAR MACROPHAGES | INFECTION | VIRULENCE | CALMETTE-GUERIN | CROSS-PRESENTATION | CELL BIOLOGY | Immunohistochemistry | Cell Proliferation | Intracellular Membranes - physiology | Humans | Myeloid Cells - physiology | Phagosomes - physiology | Myeloid Cells - ultrastructure | Lysosomes - physiology | Cell Movement - physiology | Intracellular Membranes - ultrastructure | Mycobacterium tuberculosis - physiology | Mycobacterium - ultrastructure | Phagosomes - ultrastructure | Membrane Proteins - metabolism | Mycobacterium leprae - physiology | Biomarkers - metabolism | Mycobacterium leprae - ultrastructure | Microscopy, Electron, Transmission | Host-Parasite Interactions - physiology | Mycobacterium - physiology | Cells, Cultured | Cytosol - ultrastructure | Mycobacterium tuberculosis - ultrastructure | Mycobacterium leprae - genetics | Gene Expression Regulation, Bacterial - physiology | Mycobacterium - genetics | Cell Compartmentation - physiology | Cell Division - physiology | Lysosomes - ultrastructure | Cell Death - physiology | Cytosol - physiology | Antigen Presentation - physiology | Myeloid Cells - microbiology | Mycobacterium tuberculosis - genetics | Tuberculosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Three‐dimensional ultrastructure of chloroplast pockets formed under salinity stress
by Yamane, Koji and Oi, Takao and Enomoto, Sakiko and Nakao, Tomoyo and Arai, Shigeo and Miyake, Hiroshi and Taniguchi, Mitsutaka
Plant, Cell & Environment, ISSN 0140-7791, 03/2018, Volume 41, Issue 3, pp. 563 - 575
We investigated the invagination structure of a chloroplast that surrounds organelles such as mitochondria and peroxisomes within a thin layer of chloroplast... 
salt stress | three‐dimensional reconstruction | rice | ultrastructure | chloroplast pocket | three-dimensional reconstruction | CELLS | RICE LEAF | ZEA-MAYS | LEAVES | PROTRUSIONS | PLASTID STROMULES | PLANT SCIENCES | TEMPERATURE | HIGHER-PLANTS | SCANNING-ELECTRON-MICROSCOPY | Microscopy, Electron, Transmission | Microscopy, Electron, Scanning | Chloroplasts - ultrastructure | Image Processing, Computer-Assisted | Plant Cells - ultrastructure | Oryza - physiology | Mesophyll Cells - ultrastructure | Salt Stress | Oryza - cytology | Plant Leaves - cytology | Plant Leaves - physiology | Electron microscopy | Erythromycin | Salinity | Scanning electron microscopy | Construction | Architecture | Stroma | Organelles | Cytosol | Image reconstruction | Ion beams | Mitochondria | Lipid bodies | Peroxisomes | Transmission electron microscopy | Chloroplasts | Ultrastructure | Salinity effects | Image transmission | Electrons | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Structure of the human MHC-I peptide-loading complex
by Blees, Andreas and Januliene, Dovile and Hofmann, Tommy and Koller, Nicole and Schmidt, Carla and Trowitzsch, Simon and Moeller, Arne and Tampé, Robert
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. 525 - 528
The peptide-loading complex (PLC) is a transient, multisubunit membrane complex in the endoplasmic reticulum that is essential for establishing a hierarchical... 
TAP | TRANSPORTER | PARTICLE ELECTRON CRYOMICROSCOPY | TAPASIN | MULTIDISCIPLINARY SCIENCES | MOLECULAR ARCHITECTURE | ERP57 | EM STRUCTURE DETERMINATION | CALRETICULIN P-DOMAIN | MAJOR HISTOCOMPATIBILITY COMPLEX | BINDING | ATP Binding Cassette Transporter, Subfamily B, Member 2 - chemistry | Protein Disulfide-Isomerases - metabolism | Protein Disulfide-Isomerases - ultrastructure | ATP Binding Cassette Transporter, Subfamily B, Member 3 - chemistry | Cytosol - immunology | Humans | Endoplasmic Reticulum - metabolism | ATP Binding Cassette Transporter, Subfamily B, Member 2 - ultrastructure | Histocompatibility Antigens Class I - metabolism | Multiprotein Complexes - metabolism | Endoplasmic Reticulum - chemistry | Antigen Presentation | ATP Binding Cassette Transporter, Subfamily B, Member 3 - ultrastructure | Calreticulin - metabolism | Protein Domains | Membrane Transport Proteins - metabolism | Binding Sites | Histocompatibility Antigens Class I - immunology | Models, Molecular | Histocompatibility Antigens Class I - chemistry | Burkitt Lymphoma - chemistry | Disease Progression | Membrane Transport Proteins - chemistry | Calreticulin - chemistry | Calreticulin - ultrastructure | Cryoelectron Microscopy | Multiprotein Complexes - ultrastructure | Multiprotein Complexes - chemistry | ATP Binding Cassette Transporter, Subfamily B, Member 3 - metabolism | Histocompatibility Antigens Class I - ultrastructure | Membrane Transport Proteins - ultrastructure | Models, Biological | ATP Binding Cassette Transporter, Subfamily B, Member 2 - metabolism | Cytosol - metabolism | Protein Disulfide-Isomerases - chemistry | Multiprotein Complexes - immunology | Peptides | Physiological aspects | Major histocompatibility complex | Oxidoreductase | Antigen processing | Lymphocytes T | Cell surface | Proteins | Calreticulin | Binding | Symbiosis | Translocation | Antigens | Immune response | Macromolecules | TAP protein | Lymphoma | Glycan | Burkitt's lymphoma | Immune systems | Tapasin | Microscopy | Lymphomas | Endoplasmic reticulum | Histocompatibility | ABC transporter | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Cytosolic Prion Protein in Neurons
by Mironov, Alexander, Jr and Latawiec, Diane and Wille, Holger and Bouzamondo-Bernstein, Essia and Legname, Giuseppe and Williamson, R. Anthony and Burton, Dennis and DeArmond, Stephen J and Prusiner, Stanley B and Peters, Peter J
Journal of Neuroscience, ISSN 0270-6474, 08/2003, Volume 23, Issue 18, pp. 7183 - 7193
Localizing the cellular prion protein ( PrPC) in the brain is necessary for understanding the pathogenesis of prion diseases. However, the precise... 
Membrane | Immunogold | Localization | Prion protein | Cytosolic | Hippocampus | localization | WILD-TYPE | membrane | hippocampus | SIGNAL SEQUENCE | NORMAL BRAIN | ULTRASTRUCTURAL-LOCALIZATION | CULTURED-CELLS | NEUROSCIENCES | SCRAPIE INFECTION | PRP | immunogold | cytosolic | PRECURSOR PROTEIN | DEPENDENT RETENTION | prion protein | TRANSGENIC MICE | Antibody Specificity | Dendrites - ultrastructure | Endosomes - metabolism | Neuropil - ultrastructure | Neurons - ultrastructure | Organelles - ultrastructure | Endosomes - ultrastructure | Hippocampus - ultrastructure | Cell Membrane - metabolism | Neurons - metabolism | PrPC Proteins - metabolism | PrPC Proteins - genetics | Dendrites - metabolism | Cricetinae | Synaptic Vesicles - ultrastructure | Cytosol - ultrastructure | Mice, Transgenic | Cell Membrane - ultrastructure | Mice, Inbred Strains | Immunohistochemistry - methods | Hippocampus - metabolism | Neuropil - metabolism | Animals | Fluorescent Antibody Technique | Cytosol - metabolism | Mice | Organelles - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms
by Prado, Monica and Eickel, Nina and De Niz, Mariana and Heitmann, Anna and Agop-Nersesian, Carolina and Wacker, Rahel and Schmuckli-Maurer, Jacqueline and Caldelari, Reto and Janse, Chris J and Khan, Shahid M and May, Jürgen and Meyer, Christian G and Heussler, Volker T
Autophagy, ISSN 1554-8627, 09/2015, Volume 11, Issue 9, pp. 1561 - 1579
Plasmodium parasites are transmitted by Anopheles mosquitoes to the mammalian host and actively infect hepatocytes after passive transport in the bloodstream... 
long-term live imaging | cytosolic immune response | selective autophagy | Plasmodium liver-stage | malaria | LC3 | ubiquitin | Cytosolic immune response | Ubiquitin | Malaria | Long-term live imaging | Selective autophagy | STAGE DEVELOPMENT | BACTERIA | RECOGNITION | BERGHEI | AUTOPHAGY | MATURATION | CELL BIOLOGY | MALARIA PARASITE | PROTEINS | CELL | Vacuoles - ultrastructure | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Cytosol - immunology | Humans | Virulence | Ubiquitin - metabolism | Autophagy | Immunity | Hepatocytes - parasitology | Intracellular Membranes - ultrastructure | Life Cycle Stages | Ubiquitination | Lysosomes - metabolism | Time Factors | Parasites - pathogenicity | Parasites - immunology | Imaging, Three-Dimensional | Parasites - growth & development | Plasmodium berghei - pathogenicity | Biomarkers - metabolism | Heat-Shock Proteins - metabolism | Malaria - immunology | Hepatocytes - immunology | Sporozoites - ultrastructure | Hep G2 Cells | Lysosomes - ultrastructure | Animals | Immune Evasion | Malaria - parasitology | Survival Analysis | Hepatocytes - ultrastructure | Plasmodium berghei - growth & development | Plasmodium berghei - ultrastructure | Vacuoles - metabolism | Sporozoites - physiology | Mice | Liver - parasitology | Adaptor Proteins, Signal Transducing - metabolism | Parasites - ultrastructure | Galectins - metabolism | Intracellular Membranes - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Proteomic Analysis of Dendritic Cell-Derived Exosomes: A Secreted Subcellular Compartment Distinct from Apoptotic Vesicles
by Thery, Clotilde and Boussac, Muriel and Veron, Philippe and Ricciardi-Castagnoli, Paola and Raposo, Graca and Garin, Jerome and Amigorena, Sebastian
The Journal of Immunology, ISSN 0022-1767, 06/2001, Volume 166, Issue 12, pp. 7309 - 7318
Dendritic cells constitutively secrete a population of small (50-90 nm diameter) Ag-presenting vesicles called exosomes. When sensitized with tumor antigenic... 
IN-VITRO | TRANSFERRIN RECEPTOR | SHEEP RETICULOCYTES | SYSTEMIC LUPUS-ERYTHEMATOSUS | THIOREDOXIN PEROXIDASE | ANNEXIN-II | EARLY ENDOCYTIC COMPARTMENT | GROWTH-FACTOR | IMMUNOLOGY | PLASMA-MEMBRANE | T-CELLS | Cytoplasmic Vesicles - chemistry | Cell Membrane - chemistry | Subcellular Fractions - ultrastructure | Peptide Mapping | Cytoplasmic Vesicles - metabolism | Cell Membrane - metabolism | Tumor Cells, Cultured | Dendritic Cells - metabolism | Dendritic Cells - chemistry | Endocytosis - immunology | Cell Line | Cytosol - ultrastructure | Cell Membrane - ultrastructure | Proteome - analysis | Proteome - ultrastructure | Subcellular Fractions - metabolism | Cytosol - chemistry | Animals | Apoptosis - immunology | Dendritic Cells - ultrastructure | Cytoplasmic Vesicles - ultrastructure | Cytosol - metabolism | Mice | Proteome - metabolism | Subcellular Fractions - chemistry | exosomes | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text α-synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal parkinsonism protein Atp13a2
by Kett, Lauren R and Stiller, Barbara and Bernath, Megan M and Tasset, Inmaculada and Blesa, Javier and Jackson-Lewis, Vernice and Chan, Robin B and Zhou, Bowen and Di Paolo, Gilbert and Przedborski, Serge and Cuervo, Ana Maria and Dauer, William T
Journal of Neuroscience, ISSN 0270-6474, 04/2015, Volume 35, Issue 14, pp. 5724 - 5742
Accumulating evidence from genetic and biochemical studies implicates dysfunction of the autophagic-lysosomal pathway as a key feature in the pathogenesis of... 
Genetics | ATP13A2 | Endolysosomal system | Autophagy | Parkinson’s disease | endolysosomal system | autophagy | Parkinson's disease | CHAPERONE-MEDIATED AUTOPHAGY | NEUROSCIENCES | genetics | P-TYPE ATPASE | LYSOSOMAL DYSFUNCTION | MOUSE MODEL | IN-VIVO | KUFOR-RAKEB SYNDROME | CATHEPSIN-D | NEURONAL CEROID-LIPOFUSCINOSIS | EARLY-ONSET PARKINSONISM | TIBETAN TERRIERS | Dopaminergic Neurons - pathology | Male | Endosomes - metabolism | Brain - metabolism | Exploratory Behavior - physiology | Membrane Proteins - deficiency | Lysosomes - metabolism | Membrane Proteins - ultrastructure | Brain - ultrastructure | Endosomes - ultrastructure | Parkinsonian Disorders - genetics | Adenosine Triphosphatases - ultrastructure | Disease Models, Animal | Adenosine Triphosphatases - deficiency | Parkinsonian Disorders - physiopathology | Membrane Proteins - genetics | Mice, Inbred C57BL | Cytosol - ultrastructure | Postural Balance - genetics | Mice, Knockout | Lysosomes - ultrastructure | Nerve Tissue Proteins - metabolism | Hindlimb Suspension - psychology | Motor Activity - genetics | Animals | Parkinsonian Disorders - pathology | Brain - pathology | Cytosol - metabolism | Adenosine Triphosphatases - genetics | Mice | Lipids - analysis | alpha-Synuclein - metabolism | Hydrogen-Ion Concentration | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Viral highway to nucleus exposed by image correlation analyses
by Mäntylä, Elina and Chacko, Jenu V and Aho, Vesa and Parrish, Colin R and Shahin, Victor and Kann, Michael and Digman, Michelle A and Gratton, Enrico and Vihinen-Ranta, Maija
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1152 - 11
Parvoviral genome translocation from the plasma membrane into the nucleus is a coordinated multistep process mediated by capsid proteins. We used fast confocal... 
ANOMALOUS DIFFUSION | CYTOPLASMIC TRAFFICKING | VP1N-TERMINAL SEQUENCE | PARVOVIRUS MINUTE VIRUS | CELL INFECTION | ADENOASSOCIATED VIRUS | PORE COMPLEX | MULTIDISCIPLINARY SCIENCES | CANINE PARVOVIRUS | PAIR CORRELATION | CAPSID PROTEINS | Oocytes - ultrastructure | Spectrometry, Fluorescence - methods | beta Karyopherins - genetics | Capsid - ultrastructure | Oocytes - virology | Green Fluorescent Proteins - genetics | Cell Nucleus - metabolism | Cell Nucleus - virology | Microscopy, Atomic Force | Active Transport, Cell Nucleus | Capsid - metabolism | Cell Line | Fluorescent Dyes - chemistry | Green Fluorescent Proteins - metabolism | Cats | Gene Expression | Capsid Proteins - metabolism | Oocytes - metabolism | Xenopus laevis | Cytosol - ultrastructure | Organic Chemicals - chemistry | Epithelial Cells | Cell Nucleus - ultrastructure | Virion - metabolism | Cytosol - virology | Microscopy, Confocal - methods | Parvovirus, Canine - ultrastructure | Capsid Proteins - ultrastructure | Animals | Image Processing, Computer-Assisted | Virion - ultrastructure | Cytosol - metabolism | Parvovirus, Canine - metabolism | beta Karyopherins - metabolism | Capsids | Confocal microscopy | Genomes | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text mTor mediates tau localization and secretion: Implication for Alzheimer's disease
by Tang, Zhi and Ioja, Eniko and Bereczki, Erika and Hultenby, Kjell and Li, Chunxia and Guan, Zhizhong and Winblad, Bengt and Pei, Jin-Jing
BBA - Molecular Cell Research, ISSN 0167-4889, 07/2015, Volume 1853, Issue 7, pp. 1646 - 1657
Abnormally hyperphosphorylated tau aggregates form paired helical filaments (PHFs) in neurofibrillary tangles, a key hallmark of Alzheimer's disease (AD) and... 
Tau phosphorylation | mTor | Tau secretion | Autophagy | Alzheimer's disease | MTor | NEUROFIBRILLARY TANGLES | PROTEIN-TAU | BIOCHEMISTRY & MOLECULAR BIOLOGY | CEREBROSPINAL-FLUID | PLASMA-MEMBRANE | CELL BIOLOGY | PAIRED HELICAL FILAMENTS | NEURONAL CELLS | HUMAN-BRAIN | EXTRACELLULAR TAU | UP-REGULATION | Exosomes - metabolism | Neurons - pathology | Up-Regulation | Vacuoles - ultrastructure | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Endoplasmic Reticulum - metabolism | tau Proteins - metabolism | Male | Mitochondria - ultrastructure | Endoplasmic Reticulum - ultrastructure | Alzheimer Disease - pathology | Neurofibrillary Tangles - metabolism | Protein Aggregation, Pathological - pathology | Aged, 80 and over | Female | Cell Membrane - metabolism | Neurons - metabolism | Golgi Apparatus - ultrastructure | Neurofibrillary Tangles - pathology | Cell Membrane - ultrastructure | Mitochondria - metabolism | Subcellular Fractions - metabolism | Protein Transport | tau Proteins - secretion | Intracellular Space - metabolism | Alzheimer Disease - metabolism | Cell Line, Tumor | Vacuoles - metabolism | Cytosol - metabolism | Golgi Apparatus - metabolism | Aged | Neurofibrillary Tangles - ultrastructure | Protein Aggregation, Pathological - metabolism | Analysis | Mitochondrial DNA
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Effects of hyperleptinemia in rat saliva composition, histology and ultrastructure of the major salivary glands
by Lamy, Elsa and Neves, Sandra and Ferreira, Joana and Rodrigues, Lénia and da Costa, Gonçalo and Cordeiro, Carlos and Fialho, Luísa and Lima, Mónica and Costa, Ana Rodrigues and Antunes, Célia Miguel and Lopes, Orlando and Amado, Francisco and Capela e Silva, Fernando
Archives of Oral Biology, ISSN 0003-9969, 12/2018, Volume 96, pp. 1 - 12
To study the effect of the satiety hormone, leptin, in saliva proteome and salivary gland histology and ultrastructure. Increases in blood leptin levels were... 
Salivary glands | Amylase | Salivary proteomics | Leptin | RESPONSES | INGESTION | DENTISTRY, ORAL SURGERY & MEDICINE | LEPTIN RECEPTOR | SECRETION | EXPRESSION | ALPHA-AMYLASE | Immunohistochemistry | Microscopy, Electron, Transmission | Rats, Wistar | Rats | Male | Saliva - chemistry | Amylases - metabolism | Cytosol - enzymology | Animals | Leptin - blood | Proteomics | Salivary Glands - ultrastructure | Leptin - administration & dosage | Salivary Glands - drug effects | Aluminum compounds | Amylases | Index Medicus | Dentistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway
by Wei, Yongli and Xu, Lina and Xu, Youwei and Xu, Yousong and Han, Xu and Qi, Yan and Yin, Lianhong and Sun, Huijun and Liu, Kexin and Peng, Jinyong
Food and Chemical Toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 118 - 128
Dioscin, a natural steroid saponin, has been widely investigated. However, its anti-cancer activities on human lung cancer cells are still unknown. In the... 
Dioscin | Human lung cancer cell lines | Anti-cancer | Mitochondrial pathway | DNA damage | APOPTOSIS | PROTEIN | FOOD SCIENCE & TECHNOLOGY | SOLANUM STEROIDAL GLYCOSIDES | HL-60 CELLS | DEATH | FAMILY | CYTOCHROME-C | BCL-2 | SAPONINS | LIVER-DAMAGE | TOXICOLOGY | Carcinoma, Large Cell - drug therapy | Lung Neoplasms - drug therapy | Adenocarcinoma - ultrastructure | Adenocarcinoma of Lung | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Cytosol - drug effects | Protein Transport - drug effects | Mitochondria - ultrastructure | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | Adenocarcinoma - metabolism | Inhibitory Concentration 50 | Cell Survival - drug effects | Diosgenin - analogs & derivatives | Microscopy, Electron, Transmission | Small Cell Lung Carcinoma - ultrastructure | Carcinoma, Large Cell - metabolism | Diosgenin - pharmacology | Carcinoma, Large Cell - ultrastructure | Cytosol - ultrastructure | Mitochondria - metabolism | Mitochondria - drug effects | Adenocarcinoma - drug therapy | Apoptosis Regulatory Proteins - metabolism | Signal Transduction - drug effects | Apoptosis Regulatory Proteins - antagonists & inhibitors | Lung Neoplasms - ultrastructure | Apoptosis Regulatory Proteins - agonists | Cell Line, Tumor | Cytosol - metabolism | Cell Proliferation - drug effects | S Phase - drug effects | DNA Damage | Antineoplastic Agents, Phytogenic - pharmacology | Care and treatment | Genetic aspects | Lung cancer | DNA | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Pathogenic lysosomal depletion in Parkinson's disease
by Dehay, Benjamin and Bové, Jordi and Rodríguez-Muela, Natalia and Perier, Celine and Recasens, Ariadna and Boya, Patricia and Vila, Miquel
Journal of Neuroscience, ISSN 0270-6474, 09/2010, Volume 30, Issue 37, pp. 12535 - 12544
Mounting evidence suggests a role for autophagy dysregulation in Parkinson's disease (PD). The bulk degradation of cytoplasmic proteins (including... 
RAPAMYCIN | DOPAMINERGIC NEURODEGENERATION | CHAPERONE-MEDIATED AUTOPHAGY | MITOCHONDRIA | MITOPHAGY | ALPHA-SYNUCLEIN | MUTATIONS | NEUROSCIENCES | LEWY BODIES | CELL-DEATH | MEMBRANE PERMEABILIZATION | Neurons - pathology | Substantia Nigra - pathology | Humans | Peptide Hydrolases - secretion | Autophagy - physiology | Substantia Nigra - metabolism | Parkinsonian Disorders - metabolism | Cytosol - enzymology | Lysosomes - metabolism | Neurons - ultrastructure | Dopamine - physiology | Lysosomes - pathology | Phagosomes - ultrastructure | Neurons - metabolism | Cytosol - pathology | Disease Models, Animal | Peptide Hydrolases - metabolism | Animals, Newborn | Phagosomes - metabolism | Cells, Cultured | Rats | Phagosomes - pathology | Lysosomes - ultrastructure | Animals | Cell Death - physiology | Cell Membrane Permeability - physiology | Parkinsonian Disorders - pathology | Substantia Nigra - ultrastructure | Cell Line, Tumor | Aged | Mice | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Visualizing Metal Content and Intracellular Distribution in Primary Hippocampal Neurons with Synchrotron X-Ray Fluorescence
by Colvin, Robert A and Jin, Qiaoling and Lai, Barry and Kiedrowski, Lech and Argonne National Lab. (ANL), Argonne, IL (United States)
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, pp. e0159582 - e0159582
Increasing evidence suggests that metal dyshomeostasis plays an important role in human neurodegenerative diseases. Although distinctive metal distributions... 
NERVOUS-SYSTEM | SYNAPTIC VESICLES | IRON-METABOLISM | CORTICAL-NEURONS | PLASMA-MASS SPECTROMETRY | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | DOPAMINERGIC-NEURONS | SUBSTANTIA-NIGRA | NEURODEGENERATIVE DISEASES | ZINC | Calcium - metabolism | Embryo, Mammalian | Zinc - metabolism | Endoplasmic Reticulum - metabolism | Calcium - analysis | Mitochondria - ultrastructure | Cerebral Cortex - metabolism | Endoplasmic Reticulum - ultrastructure | Freezing | Cerebral Cortex - ultrastructure | Iron - analysis | Manganese - analysis | Cell Nucleus - metabolism | Neurons - ultrastructure | Zinc - analysis | Synchrotrons | Spectrometry, X-Ray Emission | Copper - metabolism | CA1 Region, Hippocampal - metabolism | Neurons - metabolism | CA1 Region, Hippocampal - ultrastructure | Dentate Gyrus - metabolism | Rats | Mitochondria - metabolism | Cell Nucleus - ultrastructure | Iron - metabolism | Animals | Copper - analysis | Manganese - metabolism | Primary Cell Culture | Dentate Gyrus - ultrastructure | Measurement | Usage | Metals | Brain cells | Degassing of metals | Nervous system | Degeneration | Research | X-ray spectroscopy | Risk factors | Brain | Neurosciences | Calcium | Laboratories | Metal concentrations | Neurobiology | Spatial discrimination | Fluorescence | Iron | Cytosol | Accumulation | Mitochondria | Rodents | Aging | Synchrotron radiation | Neurodegenerative diseases | Neurons | Silicon nitride | Metabolism | Nitrogen | Organelles | Embryos | Zinc | Heavy metals | Neurological diseases | Dentate gyrus | Brain research | Spatial distribution | X-ray fluorescence | X radiation | Intracellular | Alzheimers disease | Endoplasmic reticulum | Hippocampus | Manganese | Index Medicus | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES | MATERIALS SCIENCE
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights