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Archives of Toxicology, ISSN 0340-5761, 1/2017, Volume 91, Issue 1, pp. 427 - 437
Chronic exposure to propiverine, a frequently prescribed pharmaceutical for treatment of overactive bladder and incontinence, provokes massive protein... 
Biomedicine, general | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Protein mistrafficking | Renal protein accumulation | Propiverine | Pharmacology/Toxicology | d -Amino acid oxidase | d-Amino acid oxidase | UBIQUITIN-PROTEASOME SYSTEM | NUCLEAR | RAT | D-Amino acid oxidase | OVERACTIVE BLADDER | HYALINE DROPLET NEPHROPATHY | ALPHA-2U-GLOBULIN | PROTEOTOXIC STRESS | TOXICOLOGY | CYTOSOLIC PROTEINS | INHIBITORS | BINDING | Benzilates - adverse effects | Humans | Rats, Inbred F344 | Cytosol - drug effects | Male | Protein Transport - drug effects | Enzyme Stability - drug effects | Cell Nucleus - enzymology | Dose-Response Relationship, Drug | Peroxisomes - drug effects | Cytosol - enzymology | Toxicity Tests, Chronic | Urological Agents - adverse effects | Cell Nucleus - metabolism | Urological Agents - administration & dosage | Female | Benzilates - administration & dosage | Kidney Tubules, Proximal - enzymology | D-Amino-Acid Oxidase - metabolism | Cholinergic Antagonists - adverse effects | Recombinant Proteins - metabolism | Kidney Tubules, Proximal - cytology | D-Amino-Acid Oxidase - chemistry | Organelle Size - drug effects | D-Amino-Acid Oxidase - genetics | Rats | Recombinant Proteins - chemistry | Peroxisomes - metabolism | Cholinergic Antagonists - administration & dosage | Catalase - metabolism | Animals | Cytosol - metabolism | Mice | Cell Nucleus - drug effects | Kidney Tubules, Proximal - drug effects | Urinary incontinence | Oxidases | Proteins | Drugs | Prescribing | Analysis | Liver | Amino acids | Bioaccumulation | Bladder | Gene loci | Occupational hazards | Pharmaceuticals
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2004, Volume 89, Issue 4, pp. 1044 - 1055
All tissues contain the enzymes that modify and remove O‐ GlcNAc dynamically from nucleocytoplasmic proteins. These enzymes have been shown to play a role in... 
TGFα | transgene | Alzheimer | diabetes | p53 | N-ACETYLGLUCOSAMINE | ADULT RATS | TETRATRICOPEPTIDE REPEATS | ALZHEIMERS-DISEASE | UBIQUITIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | TGF alpha | PANCREATIC BETA-CELLS | LINKED GLCNAC | CYTOSOLIC PROTEINS | PARKINSONS-DISEASE | DEPENDENT DEGRADATION | Histone Acetyltransferases | Apoptosis - drug effects | Injections, Intraventricular | Ubiquitin - metabolism | beta-N-Acetylhexosaminidases | Multienzyme Complexes - metabolism | N-Acetylglucosaminyltransferases - genetics | Male | Hippocampus - drug effects | Proteasome Endopeptidase Complex | RNA, Messenger - metabolism | Acetylglucosaminidase - genetics | Tumor Suppressor Protein p53 - genetics | Acetylglucosamine - metabolism | Brain - metabolism | Caspases - metabolism | Cysteine Endopeptidases - metabolism | Protein Processing, Post-Translational - drug effects | Caspase 3 | Caspases - drug effects | Neurons - metabolism | Genes, Reporter | Purkinje Cells - metabolism | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Proto-Oncogene Proteins - genetics | Mice, Inbred Strains | Multienzyme Complexes - antagonists & inhibitors | Streptozocin - pharmacology | Protein Processing, Post-Translational - physiology | Mice, Knockout | Nuclear Proteins | Brain - drug effects | Gene Expression Regulation - drug effects | Hippocampus - metabolism | Proto-Oncogene Proteins c-mdm2 | Animals | Proteins - metabolism | Mice
Journal Article
Journal Article
The Plant Cell, ISSN 1040-4651, 11/2007, Volume 19, Issue 11, pp. 3791 - 3804
Journal Article
Expert Review of Clinical Immunology, ISSN 1744-666X, 2013, Volume 9, Issue 11, pp. 1125 - 1133
Inclusion body myositis is the most common inflammatory myopathy above the age of 50. It becomes clinically apparent around the fourth decade and leads to a... 
autophagy | inclusion body myositis | muscle inflammation | protein accumulation | proinflammatory cell stress | CYTOSOLIC 5'-NUCLEOTIDASE 1A | PROTEIN | PROTEASOME INHIBITION | ALPHA | ENDOPLASMIC-RETICULUM STRESS | IMMUNOLOGY | MESSENGER-RNA | MUSCLE-FIBERS | DOUBLE-BLIND | COSTIMULATORY MOLECULE | EXPRESSION
Journal Article
Environmental and Experimental Botany, ISSN 0098-8472, 2004, Volume 52, Issue 1, pp. 53 - 61
The accumulation of specific stress proteins is a common response of plants to various environmental stresses. It was previously described that lead stimulated... 
Pathogenesis-related proteins | Abitotic stress | Lupine | Immunodetection | CYTOSOLIC CU | SEEDLINGS | pathogenesis-related proteins | GINSENG CALLUSES | lupine | PISUM-SATIVUM L | INORGANIC LEAD | PLANT SCIENCES | ENVIRONMENTAL SCIENCES | abitotic stress | immunodetection | SEQUENCE SIMILARITY | PR PROTEINS | DEHYDRIN TAS14 | BETULA-PENDULA | ZN-SUPEROXIDE DISMUTASE
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e46834
Huntington Disease (HD) is caused by an abnormal expansion of polyQ tract in the protein named huntingtin (Htt). HD pathology is featured by accumulation and... 
PEPTIDE SEQUENCES | MULTIDISCIPLINARY SCIENCES | MUTANT HUNTINGTIN | SELECTIVE UPTAKE | DISEASE | NEURODEGENERATION | CYTOSOLIC PROTEINS | ALPHA-SYNUCLEIN | MACROAUTOPHAGY | CELL | RAT-LIVER LYSOSOMES | Molecular Chaperones - metabolism | HSC70 Heat-Shock Proteins - metabolism | Humans | Autophagy | PC12 Cells | Nerve Tissue Proteins - chemistry | Lysosomes - metabolism | RNA Interference | Proteolysis | Peptide Fragments - genetics | Amino Acid Sequence | HSC70 Heat-Shock Proteins - genetics | Peptide Fragments - metabolism | Lysosome-Associated Membrane Glycoproteins - metabolism | Molecular Chaperones - genetics | Rats | Nerve Tissue Proteins - genetics | Blotting, Western | Nerve Tissue Proteins - metabolism | Huntingtin Protein | Animals | Lysosome-Associated Membrane Glycoproteins - genetics | Protein Binding | HeLa Cells | Mutation | Amino Acid Motifs - genetics | Lysosomal-Associated Membrane Protein 2 | Microscopy, Fluorescence | Proteins | Brain | Huntington's chorea | Adenoviruses | Heat shock proteins | Genetic aspects | Research | Health aspects | Huntingtons disease | Neurosciences | Huntingtin | Laboratories | Pathogenesis | Parkinsons disease | Lysosomes | Biochemistry | Accumulation | Cell adhesion & migration | Degradation | Neurodegeneration | Neostriatum | Aging | Pharmaceutical sciences | Polyglutamine | Incubation | Cortex | Pharmacology | Huntington's disease | Overexpression | Hsc70 protein | Aberration | Alzheimers disease | Phagocytosis | Apoptosis | Heat shock
Journal Article
Journal of Plant Interactions, ISSN 1742-9145, 01/2019, Volume 14, Issue 1, pp. 137 - 142
Rhizomania is one of the most damaging sugar beet diseases and is caused by Beet necrotic yellow vein virus (BNYVV). In order to interfere with viral... 
immunomodulation | transgenic plants | BNYVV | single-chain antibody fragment | rhizomania | SCFV | NIA PROTEIN | CYTOSOLIC EXPRESSION | PLANT SCIENCES | FRAGMENTS | COAT PROTEIN | RESISTANCE | TOBACCO PLANTS | INFECTION
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 03/2001, Volume 276, Issue 12, pp. 9565 - 9571
The regulation of tissue turnover requires the coordinated activity of both local and systemic factors. Nucleotides exist transiently in the extracellular... 
CA2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | DEPENDENT PROTEIN-KINASE | RECEPTOR | EXTRACELLULAR NUCLEOTIDES | SARCOMA CELLS | CYTOSOLIC CALCIUM | INTRACELLULAR FREE CALCIUM | CAMP | C-FOS EXPRESSION
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, p. 12202
Phenotypes on-demand generated by controlling activation and accumulation of proteins of interest are invaluable tools to analyse and engineer biological... 
ARABIDOPSIS-THALIANA | MESSENGER-RNA | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | IN-VIVO | HIGH-TEMPERATURE | BETA-GLUCURONIDASE | HEAT-INDUCIBLE DEGRON | END RULE PATHWAY | CYTOSOLIC PROTEINS | DNA-REPLICATION
Journal Article