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The Plant Journal, ISSN 0960-7412, 11/2007, Volume 52, Issue 3, pp. 512 - 527
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2003, Volume 373, Issue 2, pp. 381 - 391
Megalin is an integral membrane receptor belonging to the low-density lipoprotein receptor family. In addition to its role as an endocytotic receptor, megalin... 
Postsynaptic density-95 (PSD-95) | PSD-95/Drosophila discs-large/zona occludens 1 (PDZ) domain | Megalin | Synapse-associated protein 97 (SAP97) | Membrane-associated guanylate kinase (MAGUK) | megalin | ENDOCYTIC RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | membrane-associated guanylate kinase (MAGUK) | postsynaptic density-95 (PSD-95) | CYTOSOLIC ADAPTER | BRUSH-BORDER | PSD-95/Drosophilo discs-large/zona occludens 1 (PDZ) domain | PDZ DOMAINS | NA+-H+ EXCHANGE | TUMOR-SUPPRESSOR PROTEIN | LIPOPROTEIN RECEPTOR | PROXIMAL TUBULE | synapseassociated protein 97 (SAP97) | RECEPTOR-ASSOCIATED PROTEIN | HUMAN HOMOLOG | Surface Plasmon Resonance | Cells, Cultured - cytology | Humans | Molecular Sequence Data | Parathyroid Glands - enzymology | Saccharomyces cerevisiae - metabolism | Parathyroid Glands - cytology | Binding Sites - physiology | Cell Membrane - metabolism | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Low Density Lipoprotein Receptor-Related Protein-2 - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Low Density Lipoprotein Receptor-Related Protein-2 - metabolism | Cells, Cultured - enzymology | Protein Folding | Nerve Tissue Proteins - metabolism | Sequence Homology, Amino Acid | Point Mutation | Two-Hybrid System Techniques | Guanylate Kinases | Protein Binding | Cells, Cultured - metabolism | Tumor Suppressor Proteins | Nucleoside-Phosphate Kinase - metabolism | Parathyroid Glands - metabolism | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 6/2008, Volume 456, Issue 3, pp. 573 - 579
We have previously shown that NO has stimulatory and inhibitory effects on insulin secretion at low and high concentrations, respectively. The present study... 
Single channel | Biomedicine | Human Physiology | K + currents | Pancreatic β cell | Patch clamp | cGMP | ATP | currents | NO | patch clamp | pancreatic beta cell | CYTOSOLIC CA2+ CONCENTRATION | PHYSIOLOGY | ISLETS | PROTEIN-KINASE-G | K+ currents | PHOSPHOFRUCTOKINASE ACTIVITY | INDUCED INSULIN-SECRETION | RELEASE | single channel | B-CELLS | CYCLIC-GMP | SMOOTH-MUSCLE-CELLS | Diazoxide - pharmacology | Uncoupling Agents - pharmacology | Rats, Wistar | Male | Guanylate Cyclase - antagonists & inhibitors | Cyclic GMP-Dependent Protein Kinases - metabolism | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Insulin-Secreting Cells - metabolism | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | KATP Channels - drug effects | Oxadiazoles - pharmacology | Adenosine Triphosphate - metabolism | Triazenes - pharmacology | Nitric Oxide Donors - pharmacology | Cells, Cultured | Rats | Guanylate Cyclase - metabolism | Soluble Guanylyl Cyclase | KATP Channels - metabolism | Insulin - metabolism | Patch-Clamp Techniques | Animals | Cyclic GMP - metabolism | Insulin-Secreting Cells - drug effects | Membrane Potentials | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - pharmacology | Protein Kinase Inhibitors - pharmacology | Carbazoles - pharmacology | Nitric Oxide - metabolism | Insulin-Secreting Cells - enzymology | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 05/2013, Volume 305, Issue 4, pp. H521 - H532
Previously we have shown that, unlike wild-type mice (WT), heme oxygenase-1 knockout (HO-1(-/-)) mice developed nitrate tolerance and were not protected from... 
Ischemia-reperfusion | Leukocyte rolling and adhesion | Endothelial nitric oxide synthase | Protein kinase G | BAY 41-2272 | Vascular smooth muscle | BAY 60-2770 | ARACHIDONIC-ACID RELEASE | CYTOSOLIC PHOSPHOLIPASE A | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | vascular smooth muscle | SMALL-INTESTINE ROLE | leukocyte rolling and adhesion | ischemia-reperfusion | ACETYLCHOLINE-INDUCED RELAXATION | TUMOR-NECROSIS-FACTOR | ANTIINFLAMMATORY PHENOTYPE | HYDROGEN-SULFIDE ELICITS | NITRIC-OXIDE | P-SELECTIN | endothelial nitric oxide synthase | PERIPHERAL VASCULAR DISEASE | protein kinase G | Enzyme Activators - pharmacology | Hydrogen Sulfide - metabolism | Mesenteric Vascular Occlusion - drug therapy | Ischemia - genetics | Venules - drug effects | Heme Oxygenase-1 - deficiency | Mesenteric Vascular Occlusion - genetics | Time Factors | Disease Models, Animal | Membrane Proteins - genetics | Reperfusion Injury - enzymology | Vascular Diseases - genetics | Soluble Guanylyl Cyclase | Intestine, Small - blood supply | Nitric Oxide Synthase Type III - genetics | Mesenteric Artery, Superior - enzymology | Mice, Knockout | Signal Transduction - drug effects | Benzoates - pharmacology | Inflammation - prevention & control | Mice | Enzyme Activation | Vasodilation - drug effects | Inflammation - enzymology | Receptors, Cytoplasmic and Nuclear - metabolism | Leukocyte Rolling - drug effects | Tumor Necrosis Factor-alpha - metabolism | Mesenteric Artery, Superior - surgery | Ischemia - enzymology | Hydrocarbons, Fluorinated - pharmacology | Venules - enzymology | Cyclic GMP-Dependent Protein Kinases - metabolism | Dose-Response Relationship, Drug | Heme Oxygenase-1 - genetics | Membrane Proteins - deficiency | Biphenyl Compounds - pharmacology | Inflammation Mediators - metabolism | Mesenteric Vascular Occlusion - enzymology | Nitric Oxide Synthase Type III - metabolism | Reperfusion Injury - genetics | Vascular Diseases - drug therapy | Pyrazoles - pharmacology | Mesenteric Ischemia | Mice, Inbred C57BL | Guanylate Cyclase - metabolism | Receptors, Cytoplasmic and Nuclear - agonists | Vascular Diseases - physiopathology | Ischemia - physiopathology | Vascular Diseases - enzymology | Mesenteric Artery, Superior - drug effects | Animals | Reperfusion Injury - prevention & control | Ischemia - drug therapy | Reperfusion Injury - physiopathology | Inflammation - genetics | Pyridines - pharmacology | Mesenteric Vascular Occlusion - physiopathology | Nitric Oxide - metabolism | Inflammation - physiopathology | Prevention | Physiological aspects | Inflammation | Nitrates | Health aspects | Heme | Signaling and Stress Response
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 02/2014, Volume 306, Issue 4, pp. L383 - L391
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/1996, Volume 270, Issue 3, pp. L338 - L345
To directly investigate the possible role of large-conductance Ca2+-activated K+ (K-Ca) channels in nitrovasodilator-induced relaxation of airway smooth... 
Airway smooth muscle relaxation | Guanosine 3′,5′-cyclic monophosphate-dependent protein kinase | LY-83583 | Rp-8-(p-chlorophenylthio)guanosine 3′,5′-cyclic monophosphate-phosphorothioate | Methylene blue | Pig | PHYSIOLOGY | DEPENDENT PROTEIN-KINASE | PATCH-CLAMP | RELAXATION | ACTIVATED POTASSIUM CHANNELS | GUINEA-PIG | CYTOSOLIC CALCIUM | CORONARY-ARTERY | Rp-8-(p-chlorophenylthio)guanosine 3',5'-cyclic monophosphate-phosphorothioate | pig | methylene blue | airway smooth muscle relaxation | CYCLIC-GMP | RESPIRATORY SYSTEM | NITRIC-OXIDE | CGMP | guanosine 3',5'-cyclic monophosphate dependent protein kinase | Cyclic GMP - pharmacology | Calcium - pharmacology | Enzyme Inhibitors - pharmacology | Potassium Channels - physiology | Trachea - drug effects | Guanylate Cyclase - antagonists & inhibitors | Nitroprusside - pharmacology | Thionucleotides - pharmacology | Methylene Blue - pharmacology | Potassium Channels - drug effects | Cyclic GMP-Dependent Protein Kinases - metabolism | Adenosine Triphosphate - pharmacology | Muscle, Smooth - drug effects | Regression Analysis | Patch-Clamp Techniques | Animals | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclic GMP - analogs & derivatives | Membrane Potentials | Swine | Trachea - physiology | Muscle, Smooth - physiology | In Vitro Techniques | Aminoquinolines - pharmacology | Physiological aspects | Smooth muscle | Sodium nitroferricyanide | Potassium channels | Trachea
Journal Article
Journal of Pineal Research, ISSN 0742-3098, 10/2008, Volume 45, Issue 3, pp. 318 - 327
:  Recent investigations have demonstrated an influence of melatonin on insulin secretion in pancreatic β‐cells. The effects are receptor‐mediated via two... 
insulin secretion | pancreatic β‐cell | melatonin receptors | guanylate‐cyclase‐cGMP‐cascade | Melatonin receptors | Guanylate-cyclase-cGMP-cascade | Pancreatic β-cell | Insulin secretion | CYTOSOLIC CA2+ CONCENTRATION | PROTEIN-KINASE-C | PHYSIOLOGY | NITRIC-OXIDE SYNTHASE | NEUROSCIENCES | IN-VITRO | RECEPTOR HETERODIMERS | pancreatic beta-cell | HAMSTER RETINA | guanylate-cyclase-cGMP-cascade | ENDOCRINOLOGY & METABOLISM | LONG-TERM POTENTIATION | NUCLEOTIDE PHOSPHODIESTERASE | BINDING-SITES | CYCLIC-GMP SYSTEM | Cyclic GMP - pharmacology | Receptor, Melatonin, MT2 - antagonists & inhibitors | Rats, Wistar | Brain - metabolism | Dose-Response Relationship, Drug | Insulin-Secreting Cells - metabolism | Cyclic GMP - analogs & derivatives | Tryptamines - pharmacology | Diabetes Mellitus, Type 2 | Insulin Secretion | Cyclic Nucleotide-Gated Cation Channels - metabolism | Signal Transduction | Colforsin - pharmacology | Cyclic Nucleotide Phosphodiesterases, Type 2 - metabolism | Rats | Guanylate Cyclase - metabolism | Pineal Gland - chemistry | 1-Methyl-3-isobutylxanthine - pharmacology | Insulinoma - chemistry | Insulin - metabolism | Animals | Cyclic GMP - metabolism | Insulin-Secreting Cells - drug effects | Tetrahydronaphthalenes - pharmacology | Melatonin - metabolism | Cell Line, Tumor | Glucose - metabolism | Receptor, Melatonin, MT2 - metabolism | Melatonin - pharmacology
Journal Article
Journal Article