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Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2014, Volume 57, Issue 3, pp. 1097 - 1110
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 08/2009, Volume 14, Issue 8, pp. 764 - 773
The mechanisms underlying the initiation/onset of, and the recovery from, depression are still largely unknown; views that neurogenesis in the hippocampus may... 
Antidepressant | Neuroplasticity | Synapsin 1 | Depression | NCAM | Neurogenesis | TREATMENT INCREASES | ADULT NEUROGENESIS | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | antidepressant | STRESS-INDUCED CHANGES | synapsin 1 | CELL-PROLIFERATION | NEUROSCIENCES | CHRONIC FLUOXETINE | neurogenesis | MEDIAL PREFRONTAL CORTEX | RAT HIPPOCAMPUS | depression | DENTATE GYRUS | PSA-NCAM | HIPPOCAMPAL NEUROGENESIS | neuroplasticity | Rats, Wistar | Neuronal Plasticity - drug effects | Male | Hippocampus - drug effects | Methylazoxymethanol Acetate - analogs & derivatives | Pyrrolidines - pharmacology | Depression - etiology | Depression - drug therapy | Neuronal Plasticity - physiology | Prefrontal Cortex - drug effects | Behavior, Animal - drug effects | Indoles - pharmacology | Antidepressive Agents - pharmacology | Neurogenesis - drug effects | Cytostatic Agents - pharmacology | Fluoxetine - pharmacology | Affect - drug effects | Affect - physiology | Rats | Behavior, Animal - physiology | Hippocampus - cytology | Prefrontal Cortex - cytology | Methylazoxymethanol Acetate - pharmacology | Animals | Mitosis - drug effects | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Analysis of Variance | Neurogenesis - physiology | Antidiuretic Hormone Receptor Antagonists | Hippocampus - physiology | Imipramine - pharmacology | Prefrontal Cortex - physiology | Drug Combinations | Stress, Psychological - complications | Stress, Psychological - physiopathology | Antidepressants | Depression, Mental | Physiological aspects | Dosage and administration | Genetic aspects | Research | Hippocampus (Brain) | Drug therapy | Health aspects | Index Medicus
Journal Article
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 2007, Volume 111, Issue 3, pp. 657 - 666
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2014, Volume 22, Issue 14, pp. 3629 - 3641
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2009, Volume 52, Issue 7, pp. 1922 - 1934
New potent indolylarylsulfone (IAS) HIV-I NNRTIs were obtained by coupling natural and unnatural amino acids to the 2-carboxamide and introducing different... 
DESIGN | CHEMISTRY, MEDICINAL | INDOLYL ARYL SULFONES | RESILIENCE | CRYSTAL-STRUCTURES | MECHANISMS | DRUG-RESISTANCE | MUTATIONS | DERIVATIVES | RHABDOMYOLYSIS | STRATEGIES | Anti-HIV Agents - pharmacology | Cytostatic Agents - chemistry | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Molecular Conformation | Drug Resistance, Viral | Amino Acids - chemistry | Indoles - chemical synthesis | Reverse Transcriptase Inhibitors - pharmacology | Structure-Activity Relationship | Sulfones - pharmacology | Anti-HIV Agents - chemical synthesis | Reverse Transcriptase Inhibitors - chemistry | Reverse Transcriptase Inhibitors - chemical synthesis | Lymphocytes - virology | Antiviral Agents - chemistry | Sulfones - chemistry | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cytostatic Agents - pharmacology | Sulfones - chemical synthesis | Antiviral Agents - pharmacology | HIV-1 - drug effects | Models, Molecular | Antineoplastic Agents - chemistry | HIV-1 - genetics | Enterovirus B, Human - drug effects | HIV Reverse Transcriptase - metabolism | Anti-HIV Agents - chemistry | Animals | Virus Replication | Lymphocytes - drug effects | Antiviral Agents - chemical synthesis | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Protein Binding | HIV-1 - enzymology | Cell Proliferation - drug effects | Mice | Mutation | Indoles - chemistry | Cytostatic Agents - chemical synthesis | Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2015, Volume 23, Issue 13, pp. 3135 - 3146
Journal Article
Science, ISSN 0036-8075, 12/2018, Volume 362, Issue 6421, pp. 1416 - 1422
Molecularly targeted therapies aim to obstruct cell autonomous programs required for tumor growth. We show that mitogen-activated protein kinase (MARK) and... 
ACTIVATION | SECRETORY PHENOTYPE | INHIBITION | MULTIDISCIPLINARY SCIENCES | SURVEILLANCE | SENESCENCE | T-CELL | ANTITUMOR-ACTIVITY | CANCER | EXPRESSION | P53 | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Immunologic Surveillance | Tumor Necrosis Factor-alpha - metabolism | Lung Neoplasms - drug therapy | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - pathology | Molecular Targeted Therapy | Cytostatic Agents - therapeutic use | Aminopyridines - therapeutic use | Cellular Senescence | Killer Cells, Natural - immunology | Pyrimidinones - pharmacology | Purines - therapeutic use | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Cytostatic Agents - pharmacology | Benzimidazoles - therapeutic use | Pyridines - therapeutic use | Mitogen-Activated Protein Kinases | Purines - pharmacology | Mice, Inbred C57BL | Pyrimidinones - therapeutic use | Retinoblastoma Protein - metabolism | Piperazines - therapeutic use | Piperazines - pharmacology | Xenograft Model Antitumor Assays | Intercellular Adhesion Molecule-1 - metabolism | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aminopyridines - pharmacology | Benzimidazoles - pharmacology | Mice | Pyridines - pharmacology | Pyridones - therapeutic use | Mutation | Pyridones - pharmacology | Apoptosis | Cytotoxicity, Immunologic | Drug therapy, Combination | Research | Oncology, Experimental | Cancer cells | Cancer | Cell proliferation | Senescence | Toxicity | Lung cancer | Lung | Cytotoxicity | Kinases | Cyclin-dependent kinase 4 | Immunosuppressive agents | K-Ras protein | Proteins | Cyclin-dependent kinase | Adhesive strength | Immunotherapy | Cell adhesion | Natural killer cells | Immune system | Phenotypes | Cell survival | Immunomodulation | Tumor cells | Cyclin-dependent kinases | Retinoblastoma protein | MAP kinase | Immunosurveillance | Protein kinase inhibitors | Inhibitors | Surveillance | Cell death | Retinoblastoma | Tumors | Index Medicus
Journal Article
Journal Article