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Journal Article
Immunology, ISSN 0019-2805, 04/2013, Volume 138, Issue 4, pp. 298 - 306
Summary Increased CD8+ T‐cell precursor frequency (PF) precludes the requirement of CD4+ helper T (Th) cells for primary CD8+ cytotoxic T‐lymphocyte (CTL)... 
increased precursor frequency | CD40/CD40 ligand signalling | primary and memory CD8+ cytotoxic T lymphocyte responses and anti‐tumour immunity | CD4+ T‐cell help | Increased precursor frequency | HELP | CD40 | DENDRITIC CELLS | CD4+T-cell help | CD40 ligand signalling | IMMUNOLOGY | primary and memory CD8+cytotoxic T lymphocyte responses and anti-tumour immunity | RESPONSES | MAINTENANCE | IMMUNOTHERAPY | PROSTATE-CANCER | CLASS-I | GENERATION | EXPRESSION | CD8-Positive T-Lymphocytes - cytology | Cell Communication - immunology | Ovalbumin - immunology | CD40 Antigens - deficiency | CD8-Positive T-Lymphocytes - transplantation | Dendritic Cells - immunology | Lung Neoplasms - pathology | Immunologic Memory - drug effects | CD4-Positive T-Lymphocytes - immunology | Signal Transduction - immunology | T-Lymphocytes, Helper-Inducer - immunology | Precursor Cells, T-Lymphoid - metabolism | T-Lymphocytes, Helper-Inducer - cytology | Precursor Cells, T-Lymphoid - cytology | CD40 Antigens - genetics | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | T-Lymphocytes, Helper-Inducer - metabolism | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Lung Neoplasms - therapy | Immunity, Innate | Ovalbumin - pharmacology | Mice, Knockout | Xenograft Model Antitumor Assays | Lung Neoplasms - immunology | Animals | Signal Transduction - drug effects | T-Lymphocytes, Cytotoxic - metabolism | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Cell Communication - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | Precursor Cells, T-Lymphoid - immunology | Dendritic Cells - transplantation | T-Lymphocytes, Cytotoxic - cytology | CD40 Antigens - immunology | T cells | Genetic engineering | CD4+ T-cell help | Original | primary and memory CD8+ cytotoxic T lymphocyte responses and anti-tumour immunity
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7534, pp. 381 - 385
Despite antiretroviral therapy (ART), human immunodeficiency virus (HIV)-1 persists in a stable latent reservoir(1,2), primarily in resting memory CD4(+) T... 
IMMUNODOMINANCE | VIREMIA | DESIGN | VIRUS | RECOGNITION | STABILITY | MULTIDISCIPLINARY SCIENCES | VACCINE | ANTIRETROVIRAL THERAPY | INFECTION | VIRAL RESERVOIR | Anti-HIV Agents - pharmacology | Humans | Epitopes, T-Lymphocyte - genetics | Male | RNA, Viral - blood | Anti-HIV Agents - administration & dosage | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV-1 - growth & development | Genes, Viral - genetics | Anti-HIV Agents - therapeutic use | Female | Epitopes, T-Lymphocyte - immunology | gag Gene Products, Human Immunodeficiency Virus - genetics | CD4-Positive T-Lymphocytes - virology | Chronic Disease - drug therapy | HIV Infections - blood | T-Lymphocytes, Cytotoxic - immunology | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | Virus Replication - immunology | Acute Disease - therapy | HIV-1 - genetics | Mutation - genetics | HIV-1 - immunology | Animals | HIV Infections - drug therapy | Mice | Viral Load - drug effects | Virus Latency - immunology | gag Gene Products, Human Immunodeficiency Virus - immunology | Genes, Dominant - genetics | Virus Latency - genetics | Immune response | AIDS treatment | AIDS (Disease) | Physiological aspects | Research | AIDS research | T cells | Properties | Antigens | Peptides | Lymphocytes | Human immunodeficiency virus--HIV | Infections | Mutation | Gene expression | Patients
Journal Article
Journal Article
Seminars in Immunology, ISSN 1044-5323, 2013, Volume 25, Issue 4, pp. 273 - 281
Highlights • The thymic CD4 Th-lineage commitment is not fixed. • ThPOK, directs the Th-lineage fate of MHC class II restricted thymocytes. • ThPOK suppresses... 
Allergy and Immunology | Autoimmunity | CD8αβ cytotoxic T lymphocyte | Intestine | CD4 T helper cells | Plasticity | ThPOK | Lineage commitment | Functional reprogramming | Tumor | Runx3 | Protective immunity | Chronic viral infection | PRIMARY CYTOMEGALOVIRUS-INFECTION | BETA-CELLS | IMMUNOLOGY | TRANSCRIPTION FACTOR GATA-3 | FINGER PROTEIN MAZR | HELPER TYPE-1 CELLS | CD8 alpha beta cytotoxic T lymphocyte | EPITHELIAL-CELLS | COMPLEX CLASS-I | RUNX PROTEINS | T-CELL DEVELOPMENT | INTRAEPITHELIAL LYMPHOCYTES | T-Lymphocyte Subsets - immunology | T-Lymphocyte Subsets - cytology | Humans | Lymphoid Tissue - immunology | Autoimmune Diseases - genetics | CD4-Positive T-Lymphocytes - immunology | Inflammation - metabolism | Lymphocyte Activation - immunology | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | Transcription, Genetic | Thymus Gland - metabolism | Autoimmune Diseases - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | CD4-Positive T-Lymphocytes - cytology | Autoimmune Diseases - immunology | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | Lymphoid Tissue - metabolism | Inflammation - immunology | Transcription Factors - metabolism | Cell Differentiation - immunology | Animals | T-Lymphocyte Subsets - metabolism | Inflammation - genetics | Thymus Gland - immunology | Cell Lineage - immunology | Cytotoxicity, Immunologic | T cells | chronic viral infection | intestine | autoimmunity | tumor | plasticity | lineage commitment | functional reprogramming | CD8αβ Cytotoxic T lymphocyte | protective immunity
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2000, Volume 165, Issue 11, pp. 6047 - 6055
Journal Article
Cancer Research, ISSN 0008-5472, 02/2011, Volume 71, Issue 4, pp. 1406 - 1417
Journal Article
Human Immunology, ISSN 0198-8859, 2004, Volume 65, Issue 2, pp. 142 - 156
Nonantigen specific CD8 + suppressor T lymphocytes (CD8 + Ts) inhibit T-cell proliferation of antigen-specific T lymphocytes. The impossibility to generate in... 
T lymphocytes | suppression | cytokines | autoimmunity | tolerance | anergy | Autoimmunity | Tolerance | Anergy | Cytokines | Suppression | RESPONSES | DENDRITIC CELLS | MEMORY | REGULATORY PROPERTIES | CD28 | IMMUNOLOGY | Immune Tolerance - physiology | Coculture Techniques | Dendritic Cells - immunology | Humans | Receptors, Antigen, T-Cell, alpha-beta - analysis | Receptors, Interleukin - analysis | Receptors, Chemokine - analysis | Antibody-Dependent Cell Cytotoxicity - immunology | Monocytes - immunology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Histocompatibility Antigens Class I - metabolism | T-Lymphocytes, Cytotoxic - drug effects | Lymphocyte Activation - immunology | CD28 Antigens - analysis | T-Lymphocytes - drug effects | Tuberculin - immunology | Antibodies, Monoclonal - pharmacology | Antigen Presentation - immunology | Cell Differentiation - immunology | T-Lymphocytes, Regulatory - drug effects | CD3 Complex - immunology | Interleukin-2 - pharmacology | T-Lymphocytes - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - analysis | CD8-Positive T-Lymphocytes - immunology | Interleukin-10 - immunology | Lymphocyte Activation - physiology | T-Lymphocytes, Cytotoxic - cytology | Cell Communication - immunology | Receptors, Interleukin-10 | Monocytes - radiation effects | Culture Media, Conditioned - pharmacology | Interleukin-10 - physiology | Flow Cytometry | Leukocyte Common Antigens - analysis | Immune Tolerance - immunology | T-Lymphocytes, Regulatory - cytology | Interleukin-10 - metabolism | Dendritic Cells - drug effects | Immune Tolerance - drug effects | Monocytes - secretion | T-Lymphocytes, Cytotoxic - immunology | Receptors, CCR7 | Histocompatibility Antigens Class I - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | CD28 Antigens - immunology | CD8 Antigens - analysis | T-Lymphocytes - cytology | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Antigen Presentation - drug effects | Cell Proliferation - drug effects | Antibody-Dependent Cell Cytotoxicity - drug effects | CD4-Positive T-Lymphocytes - drug effects
Journal Article
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 06/2019, Volume 234, Issue 6, pp. 8509 - 8521
Journal Article