X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (448) 448
Publication (49) 49
Book / eBook (6) 6
Government Document (5) 5
Book Chapter (4) 4
Book Review (4) 4
Conference Proceeding (2) 2
Data Set (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (333) 333
index medicus (245) 245
animals (217) 217
cytotoxins - pharmacology (147) 147
mice (106) 106
cancer (103) 103
cell line, tumor (103) 103
pharmacology & pharmacy (99) 99
cytotoxins - chemistry (92) 92
oncology (92) 92
cytotoxins - pharmacokinetics (89) 89
female (86) 86
cytotoxicity (76) 76
biochemistry & molecular biology (66) 66
male (62) 62
analysis (61) 61
neoplasms - drug therapy (60) 60
cell survival - drug effects (59) 59
antineoplastic agents - pharmacology (58) 58
cytotoxins - toxicity (55) 55
chemotherapy (54) 54
apoptosis (53) 53
rats (52) 52
toxicity (50) 50
cytotoxins - therapeutic use (49) 49
cytotoxins (48) 48
antineoplastic agents - pharmacokinetics (47) 47
dose-response relationship, drug (47) 47
toxicology (46) 46
pharmacokinetics (43) 43
drugs (42) 42
in-vitro (41) 41
apoptosis - drug effects (39) 39
cells (38) 38
chemistry, medicinal (36) 36
cytotoxins - administration & dosage (36) 36
cytotoxins - metabolism (34) 34
cytotoxins - chemical synthesis (33) 33
tumors (33) 33
antineoplastic agents - therapeutic use (31) 31
article (31) 31
cell proliferation - drug effects (31) 31
antineoplastic agents (30) 30
antineoplastic agents - chemistry (30) 30
drug delivery systems (30) 30
antineoplastic agents - administration & dosage (29) 29
cytotoxin (29) 29
cell line (28) 28
expression (28) 28
research (28) 28
health aspects (27) 27
cells, cultured (26) 26
tumor cells, cultured (25) 25
cell biology (24) 24
antimitotic agents (23) 23
drug delivery systems - methods (23) 23
inhibition (23) 23
nanoparticles (22) 22
structure-activity relationship (22) 22
antitumor-activity (21) 21
chemistry, multidisciplinary (21) 21
cytotoxins - adverse effects (21) 21
in-vivo (21) 21
neoplasms - metabolism (21) 21
mice, nude (20) 20
drug screening assays, antitumor (19) 19
drug therapy (19) 19
time factors (19) 19
antineoplastic agents - chemical synthesis (18) 18
hela cells (18) 18
medicine (18) 18
neoplasms - pathology (18) 18
proteins (18) 18
solid tumors (18) 18
biology (17) 17
cancer cells (17) 17
cytotoxins - isolation & purification (17) 17
derivatives (17) 17
doxorubicin (17) 17
ligands (17) 17
medicine, research & experimental (17) 17
oxidative stress (17) 17
pharmacology/toxicology (17) 17
treatment outcome (17) 17
activation (16) 16
antineoplastic agents - toxicity (16) 16
breast neoplasms - drug therapy (16) 16
care and treatment (16) 16
cell death (16) 16
chemistry, inorganic & nuclear (16) 16
materials science, biomaterials (16) 16
models, biological (16) 16
nanoparticles - chemistry (16) 16
phase-i (16) 16
research article (16) 16
therapy (16) 16
tirapazamine (16) 16
biomedicine (15) 15
biophysics (15) 15
biotransformation (15) 15
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 03/2019, Volume 136, pp. 203 - 212
Conventional chemotherapy is associated with therapy-limiting side effects, which might be alleviated by targeted chemotherapeutics such as immunoliposomes.... 
Targeted | Immunoliposomes | Active targeting | Bioconjugation | Drug delivery | Doxorubicin | Sortase-A | Epidermal growth factor receptor | ANTIBODIES | LIPOSOMAL ANTHRACYCLINES | EFFICACY | DRUG-DELIVERY | ENTRAPMENT | IN-VITRO | GROWTH | PHARMACOLOGY & PHARMACY | POLYETHYLENE-GLYCOL | EFFICIENT | Humans | Aminoacyltransferases - pharmacokinetics | Cytotoxins - administration & dosage | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Doxorubicin - analogs & derivatives | Female | Antibiotics, Antineoplastic - pharmacokinetics | Cell Survival - physiology | Doxorubicin - administration & dosage | Cell Survival - drug effects | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Cysteine Endopeptidases - administration & dosage | Polyethylene Glycols - pharmacokinetics | Breast Neoplasms - drug therapy | Bacterial Proteins - administration & dosage | Doxorubicin - pharmacokinetics | Polyethylene Glycols - administration & dosage | Antibiotics, Antineoplastic - administration & dosage | Cysteine Endopeptidases - pharmacokinetics | Aminoacyltransferases - administration & dosage | Bacterial Proteins - pharmacokinetics | Cell Line, Tumor | Liposomes | Cytotoxins - pharmacokinetics | Drug Delivery Systems - methods | Drugs | Anthracyclines | Drug delivery systems | Chemotherapy | Epidermal growth factor | Monoclonal antibodies | Exhibitions | Precipitation (Meteorology) | Vehicles | Cancer
Journal Article
Journal Article
Medicinal Research Reviews, ISSN 0198-6325, 01/2009, Volume 29, Issue 1, pp. 29 - 64
Anticancer prodrugs designed to target specifically tumor cells should increase therapeutic effectiveness and decrease systemic side effects in the treatment... 
prodrug | bioreductive activation | hypoxia | N‐oxide | nitroreduction | target‐specific activation | gene‐directed enzyme prodrug therapy (GDEPT) | metal complex | nitroaromatic | quinone | Gene-directed enzyme prodrug therapy (GDEPT) | Nitroreduction | N-oxide | Quinone | Target-specific activation | Metal complex | Nitroaromatic | Hypoxia | Prodrug | Bioreductive activation | target-specific activation | CHEMISTRY, MEDICINAL | SELECTIVE ANTITUMOR AGENTS | MMP INHIBITOR MARIMASTAT | BENZOQUINONE ALKYLATING-AGENTS | ESCHERICHIA-COLI NITROREDUCTASE | POTENTIAL HYPOXIC CYTOTOXINS | CYTOTOXICITY IN-VITRO | HUMAN NAD(P)H-QUINONE OXIDOREDUCTASE | PHARMACOLOGY & PHARMACY | INDOLEQUINONE PHOSPHORAMIDATE PRODRUGS | gene-directed enzyme prodrug therapy (GDEPT) | ANTIBODY-DIRECTED ENZYME | N-OXIDE DERIVATIVES | Quinones - pharmacokinetics | Quinones - chemistry | Hydrocarbons, Aromatic - pharmacology | Oxidation-Reduction | Humans | Organometallic Compounds - pharmacokinetics | Prodrugs - chemistry | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Cyclic N-Oxides - pharmacokinetics | Cell Hypoxia | Hydrocarbons, Aromatic - chemistry | Cyclic N-Oxides - chemistry | Animals | Prodrugs - pharmacokinetics | Cyclic N-Oxides - pharmacology | Hydrocarbons, Aromatic - pharmacokinetics | Drug Design | Organometallic Compounds - chemistry | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Prodrugs - pharmacology | Organometallic Compounds - pharmacology | Quinones - pharmacology
Journal Article
Analytica Chimica Acta, ISSN 0003-2670, 2010, Volume 675, Issue 2, pp. 199 - 206
Journal Article
Journal Article
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, ISSN 1533-4880, 01/2016, Volume 16, Issue 1, pp. 160 - 170
Journal Article
Journal Article
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 05/2017, Volume 105, Issue 5, pp. 1433 - 1445
The aim of this work was to study the effect of different physically‐adsorbed coating polymers on the cytotoxic activity of optimized bisdemethoxycurcumin... 
physical adsorption | PLGA | nanoparticles | bisdemethoxycurcumin | cytotoxicity | MATERIALS SCIENCE, BIOMATERIALS | MOLECULAR-WEIGHT | GELATIN NANOPARTICLES | CURCUMIN | ENGINEERING, BIOMEDICAL | RELEASE | BIODEGRADABLE NANOPARTICLES | FORMULATION | DELIVERY | IN-VITRO | OVERCOMING DRUG-RESISTANCE | PARTICLE-SIZE | Neoplasms - metabolism | Curcumin - analogs & derivatives | Nanoparticles - chemistry | Curcumin - chemistry | Humans | Coated Materials, Biocompatible - pharmacology | Polyglycolic Acid - pharmacology | Drug Carriers - chemistry | Lactic Acid - pharmacokinetics | Cytotoxins - pharmacology | Nanoparticles - therapeutic use | Lactic Acid - pharmacology | Coated Materials, Biocompatible - pharmacokinetics | Lactic Acid - chemistry | Curcumin - pharmacokinetics | Curcumin - pharmacology | Coated Materials, Biocompatible - chemistry | Drug Carriers - pharmacology | Hep G2 Cells | Neoplasms - drug therapy | Polyglycolic Acid - pharmacokinetics | Polyglycolic Acid - chemistry | Cytotoxins - chemistry | Drug Carriers - pharmacokinetics | Neoplasms - pathology | Cytotoxins - pharmacokinetics | Nanoparticles | Polymer industry | Surface active agents | Adsorption | Polymers | Coatings | Particle size | Independent variables | Particulates | X-ray diffraction | Cytotoxicity | Cytotoxicity testing | Hydrophobicity | Polylactide-co-glycolide | Alcohols | Entrapment | Coating effects | Transmission electron microscopy | Polyethylene glycol | Morphology | Toxicity testing | Reaction kinetics | Biocompatibility | Kinetics | Viability | Cancer | Particle physics | Remedies | Nanostructure | Coating | Computational efficiency | Computing time
Journal Article