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Behavioural Brain Research, ISSN 0166-4328, 01/2020, Volume 377, p. 112235
Adult female rats show greater running output compared with age-matched male rats, and the midbrain dopaminergic system may account for behavioral differences... 
Tyrosine hydroxylase | CaMKII | Physical activity | D1R | PSD-95 | MAPK-1
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2015, Volume 35, Issue 41, pp. 14017 - 14030
Transient changes in striatal dopamine (DA) concentration are considered to encode a reward prediction error (RPE) in reinforcement learning tasks. Often, a... 
Striatal plasticity | Acetylcholine | Dopamine | D2R/A2AR | Reward learning | D1R/M4R | TONICALLY ACTIVE NEURONS | BASAL GANGLIA | striatal plasticity | SYNAPTIC PLASTICITY | NEUROSCIENCES | MUSCARINIC ACETYLCHOLINE-RECEPTORS | PHASIC DOPAMINE RELEASE | DARPP-32 PHOSPHORYLATION | CHOLINERGIC INTERNEURONS | IN-VIVO | MIDBRAIN DOPAMINE | reward learning | DORSAL STRIATUM | acetylcholine | dopamine | Cyclic AMP-Dependent Protein Kinases - metabolism | Membrane Potentials - drug effects | Neural Pathways - drug effects | Receptors, G-Protein-Coupled - metabolism | Enzyme Inhibitors - pharmacology | Neurotransmitter Agents - metabolism | Adenylyl Cyclases - metabolism | Enzyme Activation - drug effects | Membrane Potentials - physiology | Corpus Striatum - cytology | Neural Pathways - physiology | Animals | Signal Transduction - drug effects | Neurotransmitter Agents - pharmacology | Neurons - physiology | Signal Transduction - physiology | Models, Neurological | Reward | Enzyme Activation - physiology | Dopamine - metabolism | Life Sciences | Cellular Biology | D1R | D2R | M4R | A2AR | SRA - Molekylär biovetenskap | Biological Sciences | Data- och informationsvetenskap | Basic Medicine | Bioinformatik (beräkningsbiologi) | Neurosciences | Medical and Health Sciences | Annan biologi | Medicin och hälsovetenskap | SRA - Molecular Bioscience | Computer and Information Sciences | Naturvetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Natural Sciences | acetylcholine; D1R/M4R; D2R/A2AR; dopamine; reward learning; striatal plasticity | Other Biological Topics | Bioinformatics (Computational Biology) | Neurovetenskaper
Journal Article
Neurochemistry International, ISSN 0197-0186, 12/2019, Volume 131, p. 104543
Prolonged administration of Levodopa (L-dopa) therapy can generate L-dopa–induced dyskinesia (LID). Accumulating evidence indicates that hyper-activation of... 
D1R signaling | β-arrestin2 | GPCR | Parkinson's disease | L-dopa–induced dyskinesia
Journal Article
Neuropharmacology, ISSN 0028-3908, 08/2018, Volume 138, pp. 304 - 314
Individually, D1 and D3 dopamine receptors (D R and D R, respectively) have been implicated in L-DOPA-induced dyskinesia (LID). Of late, direct D R-D R... 
L-DOPA-Induced dyskinesia | D1R-D3R interactions | Parkinson's disease | Abnormal involuntary movements
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 08/2018, Volume 138, pp. 304 - 314
Individually, D1 and D3 dopamine receptors (D1R and D3R, respectively) have been implicated in L-DOPA-induced dyskinesia (LID). Of late, direct D1R-D3R... 
Parkinson's disease | VALIDATION | FUNCTIONAL-CHARACTERIZATION | MODEL | NEUROSCIENCES | D3 RECEPTOR | LEVODOPA-INDUCED DYSKINESIA | HEMI-PARKINSONIAN RATS | DISEASE | L-DOPA-Induced dyskinesia | D1R-D3R interactions | PHARMACOLOGY & PHARMACY | ANTAGONISTS | Abnormal involuntary movements | AGONIST
Journal Article
Hypertension, ISSN 0194-911X, 2/2016, Volume 67, Issue 2, pp. 325 - 334
The influence of a single gene on the etiology of essential hypertension may be difficult to ascertain, unless the gene interacts with other genes that are... 
Hypertension | Histone deacetylase (HDAC) | Dopamine D1 receptor (D1R) | Angiotensin II Type 1 receptor (AT1R) | Knockout mouse | G protein-coupled receptor kinase 4 (GRK4)
Journal Article
Cell Metabolism, ISSN 1550-4131, 02/2017, Volume 25, Issue 2, pp. 335 - 344
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 04/2017, Volume 323, pp. 100 - 110
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2018, Volume 9, Issue 10, pp. 990 - 995
A series of analogues featuring a 6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol unit as the arylamine “head” group of a classical D3 antagonist core structure... 
docking | D3R | D1R | D2R | 6CM4 | antagonist | dopamine receptor | 3PBL | CHEMISTRY, MEDICINAL | HIGH-AFFINITY | RATS | SCHIZOPHRENIA | COGNITION | D3 RECEPTOR | ADDICTION | D3 | D-3 RECEPTORS | ANIMAL-MODELS | CURRENT PERSPECTIVES
Journal Article
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, ISSN 1619-7070, 06/2017, Volume 44, Issue 6, pp. 1025 - 1032
Journal Article