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Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 01/2009, Volume 23, Issue 1, pp. 65 - 73
Asenapine is a novel psychopharmacologic agent under development for the treatment of schizophrenia and bipolar disorder. We determined and compared the human... 
Schizophrenia | Affinity | Bipolar disorder | Asenapine | Human receptor | NEGATIVE SYMPTOMS | PSYCHIATRY | FOCUS | SEROTONIN RECEPTORS | DISORDERS | RISPERIDONE | schizophrenia | COGNITION | NEUROSCIENCES | CLINICAL NEUROLOGY | bipolar disorder | DOPAMINE D-3 RECEPTOR | PSYCHOSIS | ATYPICAL ANTIPSYCHOTIC-DRUG | PHARMACOLOGY & PHARMACY | asenapine | human receptor | affinity | Humans | Receptors, Serotonin - drug effects | Substrate Specificity | Receptors, Serotonin - genetics | Heterocyclic Compounds, 4 or More Rings - pharmacology | Psychotropic Drugs - therapeutic use | Receptors, Dopamine - drug effects | Clozapine - pharmacology | Histamine Release - genetics | Receptors, Muscarinic - drug effects | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Receptors, Adrenergic - drug effects | Psychotropic Drugs - pharmacology | Cloning, Molecular | Receptors, Adrenergic - genetics | Receptors, Dopamine D2 - drug effects | Inhibitory Concentration 50 | Molecular Structure | Radioligand Assay | Histamine Release - drug effects | Receptors, Muscarinic - genetics | Benzodiazepines - pharmacology | Heterocyclic Compounds, 4 or More Rings - chemistry | Clinical Trials as Topic | Psychotropic Drugs - chemistry | Bipolar Disorder - drug therapy | Receptors, Dopamine D2 - physiology | Schizophrenia - drug therapy | Receptors, Dopamine - genetics | Histamine receptors | Drugs | Neuroleptics | Olanzapine | Acetylcholine receptors (muscarinic) | Mental disorders | Dopamine D4 receptors | Serotonin S1 receptors | Serotonin S7 receptors | Psychotropic drugs | Receptors | Histamine H2 receptors | Risperidone | Dopamine D2 receptors | Binding | Dopamine | Serotonin | Dopamine D3 receptors | Serotonin S6 receptors | Serotonin S2 receptors | Histamine | Dopamine D1 receptors | Serotonin receptors | Receptors (physiology) | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2018, Volume 555, Issue 7695, pp. 269 - 273
Dopamine is a neurotransmitter that has been implicated in processes as diverse as reward, addiction, control of coordinated movement, metabolism and hormonal... 
LIGANDS | CLONING | CRYSTAL-STRUCTURE | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | CHARGES | RHODOPSIN | MODEL | BETA-ADRENERGIC RECEPTOR | DISCOVERY | AGONIST | Receptors, Dopamine D4 - chemistry | Humans | Receptors, Dopamine D3 - chemistry | Receptors, Dopamine D3 - metabolism | Mutant Proteins - genetics | Models, Molecular | Crystallography, X-Ray | Mutant Proteins - metabolism | Risperidone - chemistry | Receptors, Dopamine D2 - metabolism | Receptors, Dopamine D2 - genetics | Antipsychotic Agents - chemistry | Mutant Proteins - chemistry | Drug Design | Hydrophobic and Hydrophilic Interactions | Receptors, Dopamine D2 - chemistry | Antipsychotic Agents - metabolism | Ligands | Receptors, Dopamine D4 - metabolism | Risperidone - metabolism | Kinetics | Mutation | Binding Sites | Pharmacology, Experimental | Drug interactions | Physiological aspects | Research | Risperidone | Structure | Dopamine receptors | Drugs | Neuroleptics | Parkinson's disease | Molecular structure | Mental disorders | Parkinsons disease | Schizophrenia | Mental depression | Proteins | Psychotropic drugs | Receptors | Vomiting | Reinforcement | Dopamine D2 receptors | Movement disorders | Crystal structure | Dopamine | Neurodegenerative diseases | Secretion | Attention deficit hyperactivity disorder | Nausea | Metabolism | Side effects | Addiction | Structure-function relationships
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65860
Dopamine (DA), a neurotransmitter in the nervous system, has been shown to modulate immune function. We have previously reported that five subtypes of DA... 
PROTEIN-KINASE-A | ACTIVATED T-CELLS | NUCLEAR-FACTOR | MULTIDISCIPLINARY SCIENCES | FACTOR-KAPPA-B | PROLIFERATION | SECRETION | MEDIATED MECHANISM | EXPRESSION | D2 | LYMPHOCYTES | Enzyme Activators - pharmacology | Phosphorylation | Receptors, Dopamine D3 - metabolism | Receptors, Dopamine D4 - genetics | Receptors, Dopamine D3 - genetics | Isoquinolines - pharmacology | Killer Cells, Natural - immunology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclic AMP - metabolism | Second Messenger Systems | Cyclic AMP-Dependent Protein Kinases - metabolism | Dopamine Agonists - pharmacology | Gene Expression | Colforsin - pharmacology | Adenylyl Cyclases - metabolism | Benzazepines - pharmacology | Sulfonamides - pharmacology | Mice, Inbred ICR | Animals | Dopamine Antagonists - pharmacology | Cyclic AMP Response Element-Binding Protein - metabolism | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology | Cell Line, Tumor | Receptors, Dopamine D5 - metabolism | Receptors, Dopamine D4 - metabolism | Protein Processing, Post-Translational | Quinpirole - pharmacology | Receptors, Dopamine D5 - genetics | Killer Cells, Natural - metabolism | Cytotoxicity, Immunologic | Phenols | Cyclic adenylic acid | Dopamine | Lymphocytes | Dopamine receptors | Drugs | Flow cytometry | Toxicity | Cytotoxicity | Nervous system | Lymphocytes T | mRNA | Activation | Haloperidol | Kinases | Dopamine D4 receptors | Immunosuppressive agents | Proteins | Signal transduction | Receptors | Cell activation | Modulation | Clonal selection | Physiology | Natural killer cells | Dopamine D2 receptors | Spleen | Dopamine D5 receptors | Adenosine | Immune response | Cytokines | Dopamine D3 receptors | T cell receptors | Cyclic AMP response element-binding protein | Gene expression | Lymphoma | Medicine | Cytometry | Signaling | Dopamine D1 receptors | Forskolin | Receptor mechanisms | Laboratory animals
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0136267
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 2007, Volume 320, Issue 1, pp. 1 - 13
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2016, Volume 81, Issue 1, pp. 67 - 77
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Journal Article
Journal Article