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The Journal of Immunology, ISSN 0022-1767, 04/2002, Volume 168, Issue 7, pp. 3155 - 3164
Emerging evidence suggests that NK-activatory receptors use KARAP/DAP12, CD3zeta, and FcepsilonRIgamma adaptors that contain immunoreceptor tyrosine-based... 
MHC CLASS-I | SIGNAL-TRANSDUCTION | IMMUNOGLOBULIN SUPERFAMILY | NATURAL-KILLER-CELLS | TYROSINE-PHOSPHATASE 1C | ACTIVATING RECEPTORS | IMMUNOLOGY | CYTOTOXICITY | KINASE SYK | T-CELLS | CUTTING EDGE | p21-Activated Kinases | Protein-Tyrosine Kinases - metabolism | Humans | Phosphatidylinositol 3-Kinases - metabolism | Stilbenes - pharmacology | Enzyme Activation - immunology | Protein-Tyrosine Kinases - physiology | Protein Transport - immunology | Signal Transduction - immunology | Membrane Glycoproteins - antagonists & inhibitors | Cytoplasmic Granules - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Enzyme Precursors - antagonists & inhibitors | Killer Cells, Natural - immunology | Pore Forming Cytotoxic Proteins | Tumor Cells, Cultured | Perforin | Cytotoxicity, Immunologic - drug effects | Immunosuppressive Agents - pharmacology | Syk Kinase | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Enzyme Inhibitors - pharmacology | Enzyme Precursors - physiology | Intracellular Signaling Peptides and Proteins | Down-Regulation - drug effects | Enzyme Activation - drug effects | Killer Cells, Natural - enzymology | Membrane Proteins | Adaptor Proteins, Signal Transducing | Enzyme Precursors - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | rac1 GTP-Binding Protein - physiology | Down-Regulation - immunology | K562 Cells | Phosphatidylinositol 3-Kinases - physiology | Ligands | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Cytoplasmic Granules - immunology | MAP Kinase Kinase Kinase 1 | Receptors, Immunologic - metabolism | Mitogen-Activated Protein Kinases - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | immunoreceptor tyrosine-based activation motif | Syk protein | DAP10 protein | Index Medicus | Abridged Index Medicus
Journal Article
OncoImmunology, ISSN 2162-4011, 01/2019, Volume 8, Issue 1, pp. e1509173 - e1509173
Chimeric antigen receptor (CAR) T cell immunotherapies have shown remarkable efficacy in treating multiple types of hematological malignancies but are not... 
NKG2D | CAR-T | DAP10 | glypican 3 | mesothelin | GLYPICAN-3 | IN-VIVO PERSISTENCE | INNATE | CYTOKINE | NKG2D RECEPTOR | IMMUNOLOGY | LIGANDS | ONCOLOGY | IMMUNOTHERAPY | EXPANSION | CYTOTOXICITY
Journal Article
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2017, Volume 25, Issue 5, pp. 1234 - 1247
Chimeric antigen receptors (CARs) combine T cell activation with antibody-mediated tumor antigen specificity, bypassing the need for T cell receptor (TCR)... 
toxicity | chimeric antigen receptor | γδT cell | MEDICINE, RESEARCH & EXPERIMENTAL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NONPEPTIDE ANTIGENS | GENETICS & HEREDITY | DELTA-T-CELLS | ANTITUMOR-ACTIVITY | EXPRESSION | IMMUNE EVASION | Antigens, Neoplasm - genetics | Neurons - pathology | Gene Expression | Immunotherapy - methods | Protein Engineering - methods | Antigens, Neoplasm - immunology | Lymphocyte Activation | Coculture Techniques | Humans | Mutant Chimeric Proteins - genetics | Neurons - immunology | CD28 Antigens - immunology | Gangliosides - immunology | CD3 Complex - genetics | CD28 Antigens - genetics | T-Lymphocytes - cytology | CD3 Complex - immunology | Cell Line, Tumor | Mutant Chimeric Proteins - immunology | Receptors, Antigen, T-Cell - immunology | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Gangliosides - chemistry | Cytotoxicity, Immunologic | Flow cytometry | Antigen presentation | Medical research | Toxicity | Cytotoxicity | Lymphocytes T | Inflammation | T cell receptors | Neuroblastoma | DAP10 protein | Experiments | Neuroblastoma cells | T-cell receptor | Design | Neurotoxicity | Cell activation | Scholarships & fellowships | Major histocompatibility complex | Lymphocytes | Immunotherapy | Transformed cells | Ligands | Histocompatibility | Cancer | Index Medicus | Original
Journal Article
JOURNAL OF IMMUNOLOGY RESEARCH, ISSN 2314-8861, 2019, Volume 2019, pp. 6032141 - 15
CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid... 
CELLS | RECEPTOR | IMMUNOLOGY | Leukemia | Cytotoxicity | Leukocytes | Dephosphorylation | DAP10 protein | Phosphatase | Proteins | Cell recognition | NKG2 antigen | Signal transduction | Receptors | Immunology | Toxicity testing | Inhibition | Immune system | Medical research | Immunoglobulins | Secretion | Cloning | Immunological tolerance | White blood cells | Cellular biology | γ-Interferon | Ligands | Receptor mechanisms
Journal Article
Gene, ISSN 0378-1119, 2007, Volume 401, Issue 1, pp. 154 - 164
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4373 - 15
The hexamethylene bisacetamide (HMBA) anticancer drug was dismissed due to limited efficacy in leukemic patients but it may re-enter into the clinics in HIV-1... 
Acute lymphatic leukemia | Leukemia | Cytotoxicity | Lymphocytes T | DAP10 protein | Lymphatic leukemia | Interleukin 15 | Latency | CD4 antigen | NKG2 antigen | Major histocompatibility complex | Human immunodeficiency virus--HIV | Hexamethylene bisacetamide | Natural killer cells | Cancer
Journal Article
European Journal of Immunology, ISSN 0014-2980, 04/2015, Volume 45, Issue 4, pp. 1258 - 1269
Journal Article
European journal of immunology, ISSN 0014-2980, 2017, Volume 47, Issue 7, pp. 1123 - 1135
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2011, Volume 108, Issue 45, pp. 18360 - 18365
Journal Article
The Scientific World Journal, ISSN 1537-744X, 2013, Volume 2013, pp. 429545 - 10
Journal Article
Immunology, ISSN 0019-2805, 11/2017, Volume 152, Issue 3, pp. 472 - 483
Adoptive transfer of T cells is a promising cancer therapy and expression of chimeric antigen receptors can enhance tumour recognition and T‐cell effector... 
chimeric antigen receptor | Dap10 | 8 T cell | immunotherapy | lymphoma | CD8 T cell | Lymphoma, T-Cell - immunology |