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ACS Chemical Biology, ISSN 1554-8929, 01/2018, Volume 13, Issue 1, pp. 36 - 44
Pan-Assay Interference Compounds (PAINS) are very familiar to medicinal chemists who have spent time fruitlessly trying to optimize these nonprogressible... 
LIBRARIES | AGONY | DESIGN | ECSTASY | FALSE POSITIVES | HTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FILTERS | CHEMICAL PROBES | SCREENING METHOD | DISCOVERY | Drug Evaluation, Preclinical - methods | Databases, Chemical | Structure-Activity Relationship | Reviews
Journal Article
Archives of Toxicology, ISSN 0340-5761, 11/2017, Volume 91, Issue 11, pp. 3477 - 3505
Adverse outcome pathways (AOPs) are a recent toxicological construct that connects, in a formalized, transparent and quality-controlled way, mechanistic... 
Prioritization of compounds | ACTIVATED STELLATE CELLS | 8 NLT | Liver fibrosis | Paracetamol | TUMOR-NECROSIS-FACTOR | Computational toxicology | Binning of events | Pathway unidirectionality | Interspecies extrapolation | EVIDENCE-BASED TOXICOLOGY | Vinyl acetate | Tumor promotion | Regulatory toxicology | READ-ACROSS | Multi-scale integration | NATURAL-KILLER-CELLS | DEVELOPMENTAL NEUROTOXICITY | ENVIRONMENTAL CHEMICALS | Multiple hit events Proof of non-toxicity | Metabolism | SYSTEMS TOXICOLOGY | Systems biology | CCl4 | RISK-ASSESSMENT | Biomedicine, general | Environmental Health | CCl 4 | Multiple hit events | Biomedicine | Occupational Medicine/Industrial Medicine | Pharmacology/Toxicology | Proof of non-toxicity | CCl | TOXICOLOGY | Toxicokinetics | Risk Assessment - methods | Animals | Ecotoxicology - methods | History, 21st Century | Humans | Mice, Inbred C57BL | Ecotoxicology - history | Adverse Outcome Pathways | Systems Biology | Vinyl Compounds - adverse effects | Quality Control | Pathways | Test procedures | Linearity | Toxicity testing | Data processing | Epidemiology | Modeling and Simulation | Computer Science | Medical and Health Sciences | Medicin och hälsovetenskap | Natural Sciences | Pharmacology and Toxicology | Biological Sciences | Basic Medicine | Naturvetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi
Journal Article
Obstetrics & Gynecology, ISSN 0029-7844, 10/2012, Volume 120, Issue 4, pp. 920 - 927
Most reported associations in observational clinical research are false, and the minority of associations that are true are often exaggerated. This credibility... 
WOMEN | CAUSAL INFERENCE | BIAS | WEAK ASSOCIATIONS | GUIDELINES | CANCER-EPIDEMIOLOGY | PELVIC INFLAMMATORY DISEASE | HORMONE REPLACEMENT THERAPY | INTRAUTERINE-DEVICES | MEDICAL-RESEARCH | OBSTETRICS & GYNECOLOGY | Data Interpretation, Statistical | Reproducibility of Results | Bias | Observation | Risk | Causality | Odds Ratio | Case-Control Studies | Cohort Studies
Journal Article
12.