X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
dcamkl-1 (19) 19
index medicus (16) 16
humans (12) 12
animals (10) 10
identification (10) 10
protein-serine-threonine kinases - metabolism (10) 10
mice (9) 9
stem cells (9) 9
cancer (8) 8
cell line, tumor (7) 7
doublecortin (7) 7
expression (7) 7
intracellular signaling peptides and proteins - metabolism (7) 7
oncology (7) 7
dclk1 (5) 5
epithelial-mesenchymal transition (5) 5
female (5) 5
gastroenterology & hepatology (5) 5
immunohistochemistry (5) 5
intracellular signaling peptides and proteins - genetics (5) 5
kinases (5) 5
lgr5 (5) 5
pancreatic cancer (5) 5
protein-serine-threonine kinases - genetics (5) 5
stem cells - metabolism (5) 5
article (4) 4
differentiation (4) 4
gene expression (4) 4
marker (4) 4
pancreas (4) 4
pancreatic neoplasms - pathology (4) 4
receptors, g-protein-coupled - metabolism (4) 4
tumor-growth (4) 4
abridged index medicus (3) 3
analysis (3) 3
biomarkers - metabolism (3) 3
biomarkers, tumor - metabolism (3) 3
biotechnology & applied microbiology (3) 3
cancer stem-cells (3) 3
colon (3) 3
gastroenterology and hepatology (3) 3
male (3) 3
mice, inbred c57bl (3) 3
mice, nude (3) 3
micrornas - genetics (3) 3
micrornas - metabolism (3) 3
neoplastic stem cells - metabolism (3) 3
nerve tissue proteins - metabolism (3) 3
notch (3) 3
pancreatic neoplasms - metabolism (3) 3
progression (3) 3
proteins (3) 3
proto-oncogene proteins c-myc - metabolism (3) 3
receptor, notch1 - metabolism (3) 3
research (3) 3
reverse transcriptase polymerase chain reaction (3) 3
rna, messenger - metabolism (3) 3
rna-binding proteins - metabolism (3) 3
tuft cells (3) 3
xenograft model antitumor assays (3) 3
ac133 antigen (2) 2
adult (2) 2
aged (2) 2
antigens, cd - metabolism (2) 2
antineoplastic agents - pharmacology (2) 2
benzodiazepinones - pharmacology (2) 2
binding sites (2) 2
biomarker (2) 2
brush cells (2) 2
cam kinase-like-1 (2) 2
cancer stem cell (2) 2
cancer stem cell marker (2) 2
cancer stem cells (2) 2
carcinoma, pancreatic ductal - pathology (2) 2
care and treatment (2) 2
cd133 (2) 2
cell biology (2) 2
cell differentiation (2) 2
cell proliferation - drug effects (2) 2
colon cancer (2) 2
colorectal neoplasms - genetics (2) 2
dclk-1 (2) 2
dependent mechanism (2) 2
disease models, animal (2) 2
epithelial cells - cytology (2) 2
epithelial-mesenchymal transition - genetics (2) 2
esophagus (2) 2
flow cytometry (2) 2
gastrointestinal diseases (2) 2
gastrointestinal stem cell (2) 2
gene expression regulation, neoplastic (2) 2
gene-expression (2) 2
glycoproteins - metabolism (2) 2
growth (2) 2
hct116 (2) 2
hct116 cells (2) 2
health sciences (2) 2
in-vitro (2) 2
initiating cells (2) 2
intestinal mucosa - cytology (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Cancer Research, ISSN 0008-5472, 03/2011, Volume 71, Issue 6, pp. 2328 - 2338
Pancreatic cancer is an exceptionally aggressive disease in great need of more effective therapeutic options. Epithelial-mesenchymal transition (EMT) plays a... 
INITIATING CELLS | ONCOLOGY | GROWTH | GENES | NOTCH | ACUTE MYELOID-LEUKEMIA | IDENTIFICATION | EXPRESSION | PROGRESSION | CANCER STEM-CELLS | BRAIN-TUMORS | Immunohistochemistry | ras Proteins - genetics | Pancreatic Neoplasms - metabolism | Exoribonucleases | Vimentin - metabolism | Humans | ras Proteins - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Epithelial-Mesenchymal Transition - genetics | Zinc Finger E-box Binding Homeobox 2 | RNA Interference | Biomarkers, Tumor - metabolism | Exonucleases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Gene Expression | Pancreatic Neoplasms - pathology | Protein-Serine-Threonine Kinases - genetics | Repressor Proteins - genetics | Mice, Transgenic | Pancreatic Neoplasms - genetics | Receptor, Notch1 - metabolism | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Homeodomain Proteins - genetics | 14-3-3 Proteins - metabolism | Animals | Twist-Related Protein 1 - genetics | Cell Line, Tumor | Mice | MicroRNAs - genetics | Proto-Oncogene Proteins c-myc - genetics | Mutation | Receptor, Notch1 - genetics | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus | epithelial-mesenchymal transition (EMT) | pancreatic intraepithelial neoplasia (PanIN) | Cancer Stem Cell Marker | miR-144 | 14-3-3 σ | Let-7a | vimentin | miR-200a | DCAMKL-1 | Dclk-1 | Notch-1
Journal Article
Cancer Letters, ISSN 0304-3835, 2014, Volume 351, Issue 1, pp. 151 - 161
Highlights • Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a poor survival rate. • Doublecortin-like kinase1 (DCLK1) is upregulated in... 
Hematology, Oncology and Palliative Medicine | Epithelial–mesenchymal transition | Pluripotency factors | Angiogenic factors | XMD8-92 | DCLK1 | Epithelial-mesenchymal transition | INITIATING CELLS | DOUBLECORTIN | STATISTICS | TARGETING EZH2 | IDENTIFICATION | DCAMKL-1 | CANCER STEM-CELLS | ONCOLOGY | NANOPARTICLE-BASED DELIVERY | DEPENDENT MECHANISM | EXPRESSION | RNA-Binding Proteins - genetics | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Gene Expression - drug effects | ras Proteins - metabolism | Epithelial-Mesenchymal Transition - drug effects | MicroRNAs - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Pancreatic Neoplasms - drug therapy | Antineoplastic Agents - pharmacology | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Benzodiazepinones - pharmacology | Pancreatic Neoplasms - pathology | RNA, Messenger - genetics | Pancreatic Neoplasms - enzymology | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Receptor, Notch1 - metabolism | Mice, SCID | Carcinoma, Pancreatic Ductal - pathology | Proto-Oncogene Proteins c-myc - metabolism | Carcinoma, Pancreatic Ductal - enzymology | Xenograft Model Antitumor Assays | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Tumor Burden - drug effects | Cell Line, Tumor | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | MicroRNAs - genetics | Proto-Oncogene Proteins c-myc - genetics | Receptor, Notch1 - genetics | RNA-Binding Proteins - metabolism | Care and treatment | Pancreatic cancer | Cancer | Cell growth | Kinases | Pancreas | Stem cells | Index Medicus
Journal Article
Clinical and Experimental Gastroenterology, ISSN 1178-7023, 04/2012, Volume 5, Issue 1, pp. 35 - 42
Microtubule-associated doublecortin and CaM kinase-like-1 (DCLK1) is a novel candidate marker for intestinal stem cells. The aim of our study was to assess... 
Immunohistochemistry | Adenomatous polyps | Cancer stem cell | Gastrointestinal stem cell | DCAMKL-1 | DCLK1 | Liver metastasis | Cancer
Journal Article
Gastroenterology, ISSN 0016-5085, 2009, Volume 137, Issue 2, pp. 649 - 659.e2
Journal Article
Journal of Nanobiotechnology, ISSN 1477-3155, 09/2011, Volume 9, Issue 1, pp. 40 - 40
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 06/2017, Volume 15, Issue 6, pp. 744 - 752
Doublecortin-like kinase 1 (DCLK1), a marker for intestinal and pancreatic cancer stem cells, is highly expressed in neuroblastomas. This study was conducted... 
PROGENITORS | DOUBLECORTIN-LIKE | ONCOLOGY | FOCAL-ADHESION KINASE | GROWTH | NORMALIZATION | IDENTIFICATION | INHIBITOR | DCAMKL-1 | CANCER | CELL-LINE | CELL BIOLOGY | Humans | Middle Aged | Male | Intracellular Signaling Peptides and Proteins - metabolism | Epithelial-Mesenchymal Transition - genetics | Neoplastic Stem Cells - metabolism | Aged, 80 and over | Neoplastic Stem Cells - pathology | Adult | Female | Focal Adhesion Kinase 1 - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Neuroendocrine Tumors - pathology | Pancreatic Neoplasms - pathology | Protein-Serine-Threonine Kinases - genetics | Pancreatic Neoplasms - genetics | Neuroendocrine Tumors - genetics | Xenograft Model Antitumor Assays | Tyrosine - metabolism | Animals | Adolescent | Cell Line, Tumor | Aged | Biomarkers, Tumor - genetics | Mice, Inbred BALB C | Vimentin | Mesenchyme | Liver | Stem cell transplantation | Immunoblotting | AKT protein | Neuroblastoma | Cyclin D1 | Kinases | Cell adhesion & migration | N-Cadherin | Allografts | Intestine | Animal tissues | Xenografts | Doublecortin protein | Wound healing | Extracellular signal-regulated kinase | Pharmacology | Cadherin | Nets | Pancreatic cancer | Stem cells | Focal adhesion kinase | Snail protein | Human behavior | Paxillin | Cell migration | Cancer | Tumors | Neuroendocrine tumors | Index Medicus
Journal Article
Molecular Cancer, ISSN 1476-4598, 05/2014, Volume 13, Issue 1, pp. 103 - 103
Background: Doublecortin-like kinase 1 (DCLK1) is emerging as a tumor specific stem cell marker in colorectal and pancreatic cancer. Previous in vitro and in... 
LRRK2-IN-1 | Kinase inhibitor | Small-molecule inhibitor | DCLK1 | Tumor stem cell | MARKER | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | DCAMKL-1 | ONCOLOGY | GENE-EXPRESSION | STEM-CELL | TUMOR-GROWTH | HOMOLOGY | Humans | Isoenzymes - chemistry | Pyrimidines - chemistry | Protein Kinase Inhibitors - chemistry | Laminin | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Lentivirus - genetics | Antineoplastic Agents - pharmacology | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Cell Survival - drug effects | Gene Expression | Proteoglycans | Isoenzymes - genetics | Benzodiazepinones - pharmacology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - genetics | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Benzodiazepinones - chemistry | Molecular Dynamics Simulation | Cell Movement - drug effects | Diffusion Chambers, Culture | Intracellular Signaling Peptides and Proteins - chemistry | Collagen | Cell Line, Tumor | Protein Binding | Cell Proliferation - drug effects | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - chemistry | Genetic Vectors | Drug Combinations | Isoenzymes - antagonists & inhibitors | Care and treatment | Gastrointestinal diseases | Oncology, Experimental | Pancreatic cancer | Research | Health aspects | Cancer | Health sciences | Phosphorylation | Colleges & universities | Kinases | Gene expression | Proteins | Rodents | Tumorigenesis | Colon | Pancreas | Binding sites | Tumors | Index Medicus
Journal Article
STEM CELLS, ISSN 1066-5099, 12/2011, Volume 29, Issue 12, pp. 2042 - 2050
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 04/2012, Volume 27, Issue 4, pp. 773 - 780
Background and Aim:  In Barrett's esophagus (BE), the normal esophageal squamous epithelium is replaced with a specialized metaplastic columnar epithelium. BE... 
esophageal adenocarcinoma | Musashi‐1 | doublecortin and CaM kinase‐like‐1 | Barrett's esophagus | cancer | esophagus | leucine‐rich repeat‐containing G‐protein‐coupled receptor | stem cell marker | Stem cell marker | Musashi-1 | Doublecortin and CaM kinase-like-1 | Esophageal adenocarcinoma | Cancer | Esophagus | Leucine-rich repeat-containing G-protein-coupled receptor | HIGH-GRADE DYSPLASIA | RISK-FACTORS | DCAMKL-1 | leucine-rich repeat-containing G-protein-coupled receptor | ORIGIN | THERAPY | NEOPLASIA | METAPLASIA | GASTROENTEROLOGY & HEPATOLOGY | doublecortin and CaM kinase-like-1 | EXPRESSION | PROGRESSION | Barrett Esophagus - metabolism | Up-Regulation | Receptors, G-Protein-Coupled - metabolism | Humans | Esophagus - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Stem Cells - metabolism | Nerve Tissue Proteins - metabolism | Adenocarcinoma - metabolism | Barrett Esophagus - pathology | Microarray Analysis | Esophageal Neoplasms - metabolism | Biomarkers, Tumor - metabolism | Protein-Serine-Threonine Kinases - metabolism | RNA-Binding Proteins - metabolism | Adenocarcinoma | Medical colleges | Dysplasia | RNA | Endothelium | Computer-aided manufacturing | Messenger RNA | Analysis | Stem cells | Physiological aspects | Digestive system diseases | Calmodulin | Esophageal cancer | Index Medicus
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 08/2010, Volume 299, Issue 2, pp. 303 - 310
Journal Article