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ddr1 (143) 143
index medicus (102) 102
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discoidin domain receptor 1 (46) 46
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11/2010
Atherosclerosis is an inflammatory disease of the cardiovascular system. Discoidin domain receptor 1 is a receptor tyrosine kinase that binds collagens.... 
DDR1 | Macrophage | 0306
Dissertation
Cell Adhesion & Migration, ISSN 1933-6918, 07/2018, Volume 12, Issue 4, pp. 315 - 323
Collagen is the most abundant component of tumor extracellular matrix (ECM). ECM collagens are known to directly interact with the tumor cells via cell surface... 
DDR1 | Dormancy | Cell Signaling | Metastasis | TM4SF1 | STEM-CELLS | ACTIVATION | TYROSINE KINASE | COLLAGEN-BINDING | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | INVASION | INHIBITION | DDR1 KINASE | EXTRACELLULAR-MATRIX | PROMOTES
Journal Article
RSC Advances, ISSN 2046-2069, 2017, Volume 7, Issue 6, pp. 3413 - 3418
Applanatumols Z3 (1) and Z4 (2), two novel natural product hybrids consisting of a meroterpenoid and a glycerol and three known compounds (3-5) were isolated... 
DDR1 | COCHLEAR | POTENT | ANTIOXIDANT | LUCIDUM | INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
RSC Advances, ISSN 2046-2069, 2017, Volume 7, Issue 60, pp. 38037 - 38043
Applanatumines B-D (1-3), three pairs of dimeric meroterpenoid enantiomers featuring the presence of a 6-oxo-4,4a, 5,5a, 6,8,8a, 8b-octahydrofuro[3',4':4,5]... 
DDR1 | POTENT | LUCIDUM | (+/-)-LINGZHIOL | CHEMISTRY, MULTIDISCIPLINARY | BIOSYNTHESIS
Journal Article
PLOS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12
The discoidin domain receptors, DDR1 and DDR2, are receptor tyrosine kinases that bind to and are activated by collagens. Similar to collagen-binding beta 1... 
GLYCOPROTEIN-VI | TYROSINE KINASE DDR1 | CANCER CELLS | STRUCTURAL BASIS | THROMBUS FORMATION | MULTIDISCIPLINARY SCIENCES | MIMETIC PEPTIDE | MATRIX METALLOPROTEINASE-2 | EXTRACELLULAR-MATRIX | PLATELET-ADHESION | AFFINITY BINDING
Journal Article
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, ISSN 1046-6673, 09/2019, Volume 30, Issue 9, pp. 1605 - 1624
Background The discoidin domain receptor 1 (DDR1) is activated by collagens, upregulated in injured and fibrotic kidneys, and contributes to fibrosis by... 
DDR1 | FIBROSIS | GROWTH-FACTOR RECEPTOR | ACTIN | PEPTIDE IDENTIFICATION | MYOSIN IIA | TRAFFICKING | UROLOGY & NEPHROLOGY | MICE | CELL-GROWTH | BINDING
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2015, Volume 16, Issue 6, pp. 2385 - 2390
Journal Article
World neurosurgery, ISSN 1878-8750, 08/2019
To assess the effects of miR-199a-5p on cerebral ischemic injury and its underlying mechanisms. Infarct volume, neurologic deficit scores, and brain water... 
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 01/2019, Volume 431, Issue 2, pp. 368 - 390
Discoidin domain receptors (DDR1 and DDR2) are receptor tyrosine kinases that signal in response to collagen. We had previously shown that collagen binding... 
oligomer | receptor tyrosine kinase | fibrillogenesis | atomic force microscopy | fluorescence microscopy | DDR1 | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRAFFICKING | STATE | TYROSINE KINASES | BINDING | Oligomers | Tyrosine | Fluorescence | Atomic force microscopy | Collagen | Fluorescence microscopy
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 10/2018, Volume 16, Issue 10, pp. 1590 - 1600
Discoidin domain receptor 1 (DDR1) is activated by fibrillar (triple-helical) collagens and collagen IV, which are major components of tumor stroma; thus, DDR1... 
DDR1 | INVASION | ACTIVATION | COLLAGEN RECEPTOR | ONCOLOGY | TYROSINE KINASE | ADJUVANT INTRAPERITONEAL CHEMOTHERAPY | RECURRENCE | E-CADHERIN | CANCER | FIBROBLASTS | CELL BIOLOGY
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2018, Volume 61, Issue 6, pp. 2353 - 2371
Colony stimulating factor 1 receptor kinase (CSF1R) is a well validated molecular target for anticancer drug discovery. Herein, we report the design,... 
CHEMISTRY, MEDICINAL | SOLID TUMORS | CSF-1R INHIBITOR | C-FMS | PROSTATE-CANCER | BIOLOGICAL EVALUATION | TUMOR-ASSOCIATED MACROPHAGES | 1 DDR1 INHIBITORS | FGFR INHIBITORS | FACTOR-I | DERIVATIVES
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 11/2019, Volume 1866, Issue 11, p. 118483
Discoidin domain receptor 1 (DDR1) is a tyrosine kinase receptor that is activated by fibrillar collagens. Here, we review the expression and role of DDR1 in... 
DDR1 | Brain | CNS | Oligodendrocyte | Myelin | CELLS | ACTIVATION | PROTEIN | PTK-3 | DISCOIDIN DOMAIN RECEPTOR-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | DISCOIDIN-DOMAIN-RECEPTOR-1 | CELL BIOLOGY | GENE | NEURONS | RECEPTOR TYROSINE KINASE
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 11/2019, Volume 1866, Issue 11, p. 118474
Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to... 
DDR1 | Tyrosine kinase | Skin | Lung | Kidney | Fibrosis | ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MATRIX ACCUMULATION | DOMAIN RECEPTOR 1 | RENAL-FIBROSIS | MICE LACKING | GLYCOPROTEIN VI | CELL BIOLOGY | COLLAGEN-RECEPTOR | RETRACTED ARTICLE. SEE | IDIOPATHIC PULMONARY-FIBROSIS
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 11/2019, Volume 1866, Issue 11, p. 118510
Discoidin Domain Receptor (DDR) genes and their homologues have been identified in sponges, worms and flies. These genes code for proteins that are implicated... 
Extracellular matrix | Tissue fibrosis | Remodeling | Cell adhesion | Contractility | DDR1 | IIA | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | NONMUSCLE MYOSIN | FAMILY | CELL BIOLOGY | FLIGHTLESS I | CELL-MIGRATION | INSIGHTS
Journal Article