X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (91657) 91657
Publication (11666) 11666
Newsletter (1471) 1471
Book Review (905) 905
Book Chapter (817) 817
Book / eBook (379) 379
Newspaper Article (268) 268
Conference Proceeding (175) 175
Dissertation (163) 163
Government Document (115) 115
Magazine Article (78) 78
Reference (32) 32
Web Resource (18) 18
Data Set (17) 17
Trade Publication Article (12) 12
Streaming Video (6) 6
Presentation (2) 2
Paper (1) 1
Report (1) 1
Technical Report (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (45106) 45106
humans (44991) 44991
animals (42632) 42632
apoptosis (38497) 38497
cell death (26910) 26910
mice (21103) 21103
male (18477) 18477
death (18132) 18132
cell biology (16550) 16550
female (16453) 16453
cell-death (16016) 16016
biochemistry & molecular biology (13944) 13944
expression (12629) 12629
proteins (12530) 12530
neurosciences (12301) 12301
activation (12234) 12234
rats (11954) 11954
research (11940) 11940
oncology (11928) 11928
cancer (11675) 11675
apoptosis - drug effects (11159) 11159
signal transduction (10196) 10196
research article (9522) 9522
multidisciplinary sciences (9483) 9483
immunology (9335) 9335
medicine (8643) 8643
cells, cultured (8514) 8514
cell line, tumor (8450) 8450
gene expression (8443) 8443
oxidative stress (7965) 7965
analysis (7578) 7578
article (7161) 7161
science (6970) 6970
health aspects (6704) 6704
physiological aspects (6659) 6659
inflammation (6531) 6531
kinases (6402) 6402
cell death - drug effects (6387) 6387
biochemistry (6378) 6378
biology (6237) 6237
middle aged (6218) 6218
rodents (5830) 5830
apoptosis - physiology (5734) 5734
receptor (5726) 5726
neurons (5722) 5722
phosphorylation (5650) 5650
mitochondria (5626) 5626
mice, inbred c57bl (5602) 5602
adult (5367) 5367
genetic aspects (5296) 5296
cell line (5144) 5144
pharmacology & pharmacy (5069) 5069
inhibition (5005) 5005
brain (4962) 4962
aged (4948) 4948
in-vivo (4853) 4853
nf-kappa-b (4781) 4781
medicine, research & experimental (4760) 4760
disease models, animal (4713) 4713
care and treatment (4705) 4705
tumors (4594) 4594
in-vitro (4582) 4582
rats, sprague-dawley (4531) 4531
survival (4407) 4407
mortality (4397) 4397
programmed cell-death (4395) 4395
autophagy (4393) 4393
cell survival (4322) 4322
immunohistochemistry (4301) 4301
cells (4240) 4240
physiology (4232) 4232
protein (4232) 4232
mutation (4199) 4199
cell survival - drug effects (4177) 4177
caspases - metabolism (4171) 4171
flow cytometry (4169) 4169
time factors (4112) 4112
caspase (3948) 3948
signal transduction - drug effects (3930) 3930
receptors (3908) 3908
cell proliferation (3873) 3873
studies (3795) 3795
neurons - drug effects (3791) 3791
risk factors (3747) 3747
cell cycle (3723) 3723
cytotoxicity (3682) 3682
mice, knockout (3675) 3675
gene-expression (3631) 3631
dose-response relationship, drug (3597) 3597
cytokines (3590) 3590
neurons - metabolism (3579) 3579
ischemia (3499) 3499
genes (3455) 3455
lymphocytes (3455) 3455
chemotherapy (3442) 3442
blotting, western (3403) 3403
disease (3304) 3304
ligands (3177) 3177
antineoplastic agents - pharmacology (3169) 3169
reactive oxygen species - metabolism (3157) 3157
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (171) 171
Robarts - Stacks (87) 87
UofT at Mississauga - Stacks (44) 44
Collection Dvlpm't (Acquisitions) - Vendor file (35) 35
UofT at Scarborough - Stacks (33) 33
Online Resources - Online (27) 27
UTL at Downsview - May be requested (27) 27
Collection Dvlpm't (Acquisitions) - Closed Orders (19) 19
St. Michael's College (John M. Kelly) - 2nd Floor (18) 18
Trinity College (John W Graham) - Stacks (13) 13
Knox College (Caven) - Stacks (11) 11
OISE - Stacks (11) 11
St. Michael's College (John M. Kelly) - 3rd Floor (10) 10
Victoria University E.J. Pratt - Stacks (9) 9
Providence Healthcare - Stacks (8) 8
Victoria University Emmanuel College - Stacks (8) 8
Regis College - Stacks (7) 7
St. Augustine's Seminary - Stacks (6) 6
Trinity College (John W Graham) - Storage (5) 5
Law (Bora Laskin) - Stacks (4) 4
Baycrest Hospital - Stacks (3) 3
New College (Ivey) - Stacks (3) 3
Pontifical Inst. Mediaeval Studies - Library use only (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (3) 3
Earth Sciences (Noranda) - Stacks (2) 2
Gerstein Science - Not Returned (2) 2
Gerstein Science - Reference (2) 2
Institute for Christian Studies - Stacks (2) 2
Markham Stouffville Hospital - Stacks (2) 2
Providence Healthcare - Lost (2) 2
Trinity College (John W Graham) - Reference (2) 2
Victoria University Emmanuel College - Reference (2) 2
Baycrest Hospital - Wellness Library (1) 1
Chemistry (A D Allen) - Stacks (1) 1
Credit Valley Hospital - Stacks (1) 1
Earth Sciences (Noranda) - Circulation Desk (1) 1
Earth Sciences (Noranda) - Oversize (1) 1
Faculty of Information - Subject Analysis Systems (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reserve desk (1) 1
Holland Bloorview Kids Rehabilitation - Stacks (1) 1
Humber River Regional Hospital - Church Stacks (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
OISE - Missing (1) 1
Providence Healthcare - Reference (1) 1
Regis College - Storage (1) 1
Robarts - Not Returned (1) 1
Robarts - Storage (1) 1
Scarborough Hospital - Birchmount (1) 1
Scarborough Hospital - General (1) 1
Scarborough Hospital - Hospital Department (1) 1
St. Augustine's Seminary - Reference (1) 1
St. Michael's Hospital - Stacks (1) 1
Trillium Health Centre - Moving to offsite: no requests (1) 1
Trinity College (John W Graham) - Wycliffe Storage (1) 1
UofT Schools - Stacks (1) 1
UofT at Mississauga - Circulation Desk (1) 1
UofT at Mississauga - Reference (1) 1
UofT at Scarborough - May be requested in 6-10 wks (1) 1
UofT at Scarborough - Withdrawn (1) 1
Victoria University E.J. Pratt - Circulation Desk (1) 1
Victoria University E.J. Pratt - Northrop Frye (1) 1
Victoria University E.J. Pratt - Oversize (1) 1
Victoria University E.J. Pratt - Virginia Woolf (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (93753) 93753
Japanese (200) 200
Chinese (199) 199
French (164) 164
German (113) 113
Spanish (99) 99
Russian (60) 60
Korean (38) 38
Polish (35) 35
Portuguese (27) 27
Czech (9) 9
Dutch (7) 7
Italian (7) 7
Danish (6) 6
Hungarian (5) 5
Swedish (5) 5
Turkish (5) 5
Croatian (4) 4
Lithuanian (3) 3
Arabic (2) 2
Slovak (2) 2
Ukrainian (2) 2
Bosnian (1) 1
Finnish (1) 1
Indonesian (1) 1
Latin (1) 1
Norwegian (1) 1
Persian (1) 1
Serbian (1) 1
Slovenian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


International Immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 50, pp. 20054 - 20059
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2046 - 2058
T cell Ig and ITIM domain (TIGIT) is an inhibitory receptor expressed by activated T cells, Tregs, and NI( cells. Here, we determined that TIGIT is upregulated... 
MEDICINE, RESEARCH & EXPERIMENTAL | ADHESION MOLECULE | LIGANDS | DNAM-1 | INHIBITORY RECEPTORS | CHRONIC VIRAL-INFECTION | NECTIN-2 CD112 | UP-REGULATION | PVR CD155 | EXPRESSION | POLIOVIRUS RECEPTOR CD155 | Up-Regulation | Receptors, Immunologic - physiology | Receptors, Virus - biosynthesis | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Neoplasm Proteins - antagonists & inhibitors | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Programmed Cell Death 1 Receptor - physiology | Receptors, Virus - genetics | Receptors, Immunologic - antagonists & inhibitors | Receptors, Immunologic - biosynthesis | Programmed Cell Death 1 Receptor - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Interleukin-2 Receptor beta Subunit - genetics | Neoplasm Proteins - genetics | Antibodies, Monoclonal - immunology | Antigen-Presenting Cells - metabolism | Antigens, Neoplasm - immunology | Lymphocyte Activation | Neoplasm Proteins - biosynthesis | Antibodies, Monoclonal - pharmacology | Immunophenotyping | Interleukin-2 Receptor beta Subunit - biosynthesis | Melanoma - pathology | Antigen-Presenting Cells - immunology | Melanoma - immunology | Antigens, Differentiation, T-Lymphocyte - genetics | Cell Line, Tumor | T-Cell Antigen Receptor Specificity | Immunologic Memory | Antigens, Differentiation, T-Lymphocyte - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Programmed Cell Death 1 Receptor - genetics | Cytokines - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Oncology | Immunology | Dermatology | Therapeutics
Journal Article
2005, Cancer drug discovery and development., ISBN 9781588291721, xi, 374
An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing... 
Cell receptors | Cellular signal transduction | Molecular aspects | Apoptosis | Cancer | Clinical & internal medicine | Oncology | Medicine & Public Health
Book
Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 45, pp. 32343 - 32356
Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has shown efficacy in a phase 2 clinical trial, development of resistance to TRAIL by... 
Reactive Oxygen Species (ROS) | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | MEDIATED APOPTOSIS | Limonoid | ANTITUMOR-ACTIVITY | Cancer Therapy | MAP Kinases (MAPKs) | Death Receptor | Trail | MELIA-AZADIRACHTA L | CHOP | CHOLANGIOCARCINOMA CELLS | SURVIVAL PROTEINS | NF-KAPPA-B | UP-REGULATION | APO2L/TRAIL-INDUCED APOPTOSIS | Anticancer Drug | COLON-CARCINOMA | Apoptosis | Neoplasms - metabolism | Transcription Factor CHOP - genetics | Reactive Oxygen Species - metabolism | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Tumor Suppressor Protein p53 - genetics | Dose-Response Relationship, Drug | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Neoplasms - genetics | Antineoplastic Agents - pharmacology | Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics | Gene Expression Regulation, Neoplastic - drug effects | Apoptosis Regulatory Proteins - biosynthesis | Response Elements | Cell Survival | Tumor Suppressor Protein p53 - metabolism | Down-Regulation - drug effects | Neoplasms - drug therapy | Up-Regulation - drug effects | Limonins - pharmacology | MAP Kinase Signaling System - drug effects | Cell Line, Tumor | Neoplasms - pathology | Transcription Factor CHOP - metabolism | Signal Transduction
Journal Article
Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 7/2010, Volume 460, Issue 2, pp. 525 - 542
Glutamate excitotoxicity is a hypothesis that states excessive glutamate causes neuronal dysfunction and degeneration. As glutamate is a major excitatory... 
TRP channel | Sodium–calcium exchange | Biomedicine | Human Physiology | Calcium | Neuroprotective drugs | Excitotoxicity | Neuronal cell death | Glutamate | NMDA receptor | Free radical | Gap junction | Sodium-calcium exchange | APOPTOSIS-INDUCING FACTOR | PRESYNAPTIC KAINATE RECEPTORS | PHYSIOLOGY | NITRIC-OXIDE SYNTHASE | ANEURYSMAL SUBARACHNOID HEMORRHAGE | FOCAL CEREBRAL-ISCHEMIA | CULTURED CORTICAL-NEURONS | INTRACELLULAR ZINC RELEASE | TRAUMATIC BRAIN-INJURY | MANGANESE-SUPEROXIDE-DISMUTASE | METHYL-D-ASPARTATE | Caspases - physiology | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Receptors, Kainic Acid | Calcium - metabolism | Humans | Nerve Degeneration - physiopathology | Receptors, Metabotropic Glutamate - physiology | Calpain - physiology | Zinc - physiology | Free Radicals - metabolism | Sodium-Calcium Exchanger - therapeutic use | Free Radical Scavengers - therapeutic use | Hypothalamus - drug effects | Glutamic Acid - adverse effects | Receptors, AMPA - physiology | Glutamic Acid - physiology | Nitric Oxide - physiology | Receptors, N-Methyl-D-Aspartate - physiology | Antioxidants - therapeutic use | Animals | Neurodegenerative Diseases - physiopathology | Cell Death - physiology | Neurotoxicity Syndromes - physiopathology | Receptors, Glutamate - physiology | Receptors, AMPA - antagonists & inhibitors | Methyl aspartate | Brain | Nervous system diseases | Multiple sclerosis | Parkinson's disease | Neurons | Cell death | Physiological aspects | Injuries | Index Medicus
Journal Article