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1. Full Text Aging of hematopoietic stem cells
by de Haan, Gerald and Lazare, Seka
Blood, ISSN 0006-4971, 2018, Volume 131, Issue 5, pp. 479 - 487
LIFE-SPAN | DIFFERENTIATION PROGRAMS | CLONAL HEMATOPOIESIS | BONE-MARROW | IN-VIVO | SELF-RENEWAL | DEFICIENT MICE | PROLIFERATIVE CAPACITY | Journal Article | MYELODYSPLASTIC SYNDROMES | BLOOD-CELLS | Life Sciences & Biomedicine | Hematology | Science & Technology | Aging - blood | Epigenesis, Genetic - physiology | Animals | Aging - physiology | Humans | Cellular Senescence - physiology | Hematopoietic Stem Cells - physiology | Hematopoiesis - physiology | Autophagy - physiology | Mitochondria - physiology | Index Medicus | Abridged Index Medicus
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2. Full Text Role of IL-4 receptor α–positive CD4+ T cells in chronic airway hyperresponsiveness
by Kirstein, Frank, PhD and Nieuwenhuizen, Natalie E., PhD and Jayakumar, Jaisubash, PhD and Horsnell, William G.C., PhD and Brombacher, Frank, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 137, Issue 6, pp. 1852 - 1862.e9
Allergy and Immunology | gene-deficient mice | acute allergic airway disease | TH2 cell | chronic asthma | IL-4 | IL-13 | cytokine receptors | 2 cell | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | T-Lymphocyte Subsets - immunology | Asthma - metabolism | Immunoglobulin G - blood | Ovalbumin - immunology | Humans | Th2 Cells - immunology | Immunoglobulin E - blood | Interleukin-4 Receptor alpha Subunit - genetics | CD4-Positive T-Lymphocytes - immunology | Immunoglobulin E - immunology | Immunoglobulin G - immunology | Asthma - immunology | Respiratory Hypersensitivity - physiopathology | Female | Leukocyte Count | Disease Models, Animal | Interleukin-4 Receptor alpha Subunit - metabolism | Cytokines - metabolism | CD4-Positive T-Lymphocytes - metabolism | Respiratory Hypersensitivity - metabolism | Respiratory Hypersensitivity - immunology | Th2 Cells - metabolism | Asthma - genetics | Mice, Knockout | Respiratory Hypersensitivity - genetics | Animals | T-Lymphocyte Subsets - metabolism | Mice | Chronic Disease | Index Medicus | Abridged Index Medicus
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3. Full Text Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
by Dijkstra, Krijn K and Cattaneo, Chiara M and Weeber, Fleur and Chalabi, Myriam and van de Haar, Joris and Fanchi, Lorenzo F and Slagter, Maarten and van der Velden, Daphne L and Kaing, Sovann and Kelderman, Sander and van Rooij, Nienke and van Leerdam, Monique E and Depla, Annekatrien and Smit, Egbert F and Hartemink, Koen J and de Groot, Rosa and Wolkers, Monika C and Sachs, Norman and Snaebjornsson, Petur and Monkhorst, Kim and Haanen, John and Clevers, Hans and Schumacher, Ton N and Voest, Emile E
Cell (Cambridge), ISSN 0092-8674, 09/2018, Volume 174, Issue 6, pp. 1586 - 1598.e12
non-small cell lung cancer | colorectal cancer | organoids | T cell | immunotherapy | microsatellite instable | adoptive cell transfer | immune checkpoint blockade | mismatch repair deficient | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Carcinoma, Non-Small-Cell Lung - pathology | Leukocytes, Mononuclear - metabolism | Coculture Techniques | Humans | Lung Neoplasms - metabolism | Middle Aged | Carcinoma, Non-Small-Cell Lung - metabolism | Lung Neoplasms - pathology | Male | T-Lymphocytes - cytology | Lymphocyte Activation - drug effects | T-Lymphocytes - drug effects | Female | Leukocytes, Mononuclear - cytology | T-Lymphocytes - immunology | Aged | Cell Culture Techniques | Tumor Cells, Cultured | Colorectal Neoplasms - pathology | In Vitro Techniques | Colorectal Neoplasms - metabolism | Interferon-gamma - pharmacology | T cells | Lung cancer, Non-small cell | Analysis | Immunotherapy | Colorectal cancer | Cancer | Index Medicus
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4. Full Text Rapidly induced, T-cell-independent xenoantibody production is mediated by marginal zone B cells and requires help from NK cells
by Li, Shengqiao and Yan, Yehong and Lin, Yuan and Bullens, Dominique M and Rutgeerts, Omer and Goebels, Jozef and Segers, Constant and Boon, Louis and Kasran, Ahmad and De Vos, Rita and Dewolf-Peeters, Christiane and Waer, Mark and Billiau, An D
Blood, ISSN 0006-4971, 12/2007, Volume 110, Issue 12, pp. 3926 - 3935
Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Communication - immunology | B-Lymphocytes - cytology | Transplantation, Heterologous - immunology | Antibodies, Heterophile - immunology | Immunoglobulin M - immunology | CD40 Ligand - immunology | Mice, Knockout | Killer Cells, Natural - cytology | Models, Immunological | Animals | B-Lymphocytes - immunology | Mice, Nude | Killer Cells, Natural - immunology | T-Lymphocytes - immunology | Mice | CD40 Ligand - antagonists & inhibitors | Antibody Formation - genetics | Index Medicus | Abridged Index Medicus
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5. Full Text Phosphoregulation of K+‐Cl− cotransporters during cell swelling: Novel insights
by Frenette‐Cotton, Rachelle and Marcoux, Andrée‐Anne and Garneau, Alexandre P and Noel, Micheline and Isenring, Paul
Journal of cellular physiology, ISSN 0021-9541, 01/2018, Volume 233, Issue 1, pp. 396 - 408
cation‐Cl− cotransporters | membrane transport | K+‐Cl− cotransporters | lysine‐deficient protein kinases | protein phosphatase 1 | Cl | cation-Cl | lysine-deficient protein kinases | cotransporters | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation | Signal Transduction | Cell Size - drug effects | Xenopus laevis | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Symporters - metabolism | Protein Phosphatase 1 - antagonists & inhibitors | Protein Phosphatase 1 - metabolism | Animals | Symporters - genetics | Protein Phosphatase 1 - genetics | Oxazoles - pharmacology | Protein Processing, Post-Translational | Symporters - drug effects | Mutation | Protein-Serine-Threonine Kinases - metabolism | Lysine | Protein kinases | Phosphatases | Efflux | Alternative splicing | Alanine | Ion concentration | Salts | Swelling | Proline | Dephosphorylation | C-Terminus | Kinases | Phosphatase | Cell surface | Play | Allosteric properties | Chloride | Isoforms | Cell size | Intracellular | Potassium | Index Medicus
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6. Full Text IL-25 enhances T H 17 cell–mediated contact dermatitis by promoting IL-1β production by dermal dendritic cells
by Suto, Hajime and Nambu, Aya and Morita, Hideaki and Yamaguchi, Sachiko and Numata, Takafumi and Yoshizaki, Takamichi and Shimura, Eri and Arae, Ken and Asada, Yousuke and Motomura, Kenichiro and Kaneko, Mari and Abe, Takaya and Matsuda, Akira and Iwakura, Yoichiro and Okumura, Ko and Saito, Hirohisa and Matsumoto, Kenji and Sudo, Katsuko and Nakae, Susumu
Journal of allergy and clinical immunology, ISSN 0091-6749, 11/2018, Volume 142, Issue 5, pp. 1500 - 1509.e10
gene-deficient mice | 2 | thymic stromal lymphopoietin | T | 17 | IL-25 | contact hypersensitivity | IL-33 | Fluorescein isothiocyanate | Immunohistochemistry | Flow cytometry | Leukocyte migration | Pathogenesis | Differentiation (biology) | Helper cells | Lymphocytes T | Dermatitis | Cell adhesion & migration | Thymus | Cell activation | Lymphocytes | Bone marrow | Natural killer cells | Enzyme-linked immunosorbent assay | Immune system | Lymphatic system | Lymphoid cells | Cytokines | Dendritic cells | Hypersensitivity | Isothiocyanate | Inflammation | Gene expression | Cell differentiation | IL-1β | Thymic stromal lymphopoietin | Contact dermatitis | Fluorescein | Skin | Mice | Cell migration | Neutralization
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7. Full Text B‐cells and IL‐4 promote methylcholanthrene‐induced carcinogenesis but there is no evidence for a role of T/NKT‐cells and their effector molecules (Fas‐ligand, TNF‐α, perforin)
by Kammertoens, Thomas and Qin, Zhihai and Briesemeister, Dana and Bendelac, Albert and Blankenstein, Thomas
International journal of cancer, ISSN 0020-7136, 10/2012, Volume 131, Issue 7, pp. 1499 - 1508
immune‐deficient mice | immunosurveillance | chemical carcinogenesis | methylcholanthrene | immune-deficient mice | Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Tumors | Tumor Necrosis Factor-alpha - metabolism | Fas Ligand Protein - metabolism | Perforin - genetics | Tumor Necrosis Factor-alpha - genetics | Male | Cell Transformation, Neoplastic - chemically induced | Interferon-gamma - metabolism | T-Lymphocytes - metabolism | Cell Transformation, Neoplastic - genetics | Natural Killer T-Cells - metabolism | Female | Interferon-gamma - genetics | Interleukin-4 - genetics | B-Lymphocytes - metabolism | Methylcholanthrene | Interleukin-4 - metabolism | Mice, Inbred C57BL | Mice, Knockout | Cell Transformation, Neoplastic - immunology | Animals | B-Lymphocytes - immunology | Mice, Nude | Environment | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Perforin - metabolism | Fas Ligand Protein - genetics | Natural Killer T-Cells - immunology | Tumor necrosis factor | Development and progression | Universities and colleges | T cells | Carcinogenesis | Population genetics | Ligands | Genetics | Cellular biology | Rodents | Cancer | Index Medicus
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8. Full Text Fumarate Hydratase–deficient Renal Cell Carcinoma Is Strongly Correlated With Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome
by Trpkov, Kiril and Hes, Ondrej and Agaimy, Abbas and Bonert, Michael and Martinek, Petr and Magi-Galluzzi, Cristina and Kristiansen, Glen and Lüders, Christine and Nesi, Gabriella and Compérat, Eva and Sibony, Mathilde and Berney, Daniel M and Mehra, Rohit and Brimo, Fadi and Hartmann, Arndt and Husain, Arjumand and Frizzell, Norma and Hills, Kirsten and Maclean, Fiona and Srinivasan, Bhuvana and Gill, Anthony J
The American journal of surgical pathology, ISSN 0147-5185, 07/2016, Volume 40, Issue 7, pp. 865 - 875
renal cancer | 2SC | fumarate hydratase-deficient RCC | HLRCC | fumarate hydratase | succination | Pathology | Life Sciences & Biomedicine | Surgery | Science & Technology | Immunohistochemistry | Cysteine - analogs & derivatives | Neoplastic Syndromes, Hereditary - pathology | Tissue Array Analysis | Uterine Neoplasms - pathology | Humans | Middle Aged | Male | Psychomotor Disorders - complications | Fumarate Hydratase - deficiency | Kidney Neoplasms - diagnosis | Young Adult | Leiomyomatosis - diagnosis | Kidney Neoplasms - etiology | Skin Neoplasms - diagnosis | Cysteine - biosynthesis | Leiomyomatosis - pathology | Germ-Line Mutation | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Uterine Neoplasms - diagnosis | Carcinoma, Renal Cell - etiology | Skin Neoplasms - pathology | Uterine Neoplasms - genetics | Muscle Hypotonia - complications | Cysteine - analysis | Neoplastic Syndromes, Hereditary - diagnosis | Fumarate Hydratase - genetics | Carcinoma, Renal Cell - diagnosis | Skin Neoplasms - genetics | Aged | Leiomyomatosis - genetics | Metabolism, Inborn Errors - complications | Index Medicus
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