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delta-4-3-ketosteroid 5-beta-reductase (18) 18
biochemistry & molecular biology (12) 12
endocrinology & metabolism (7) 7
rat-liver (6) 6
5 beta-reductase (5) 5
animals (5) 5
oxidoreductases - genetics (5) 5
5β-reductase (4) 4
inborn error (4) 4
keto reductase superfamily (4) 4
liver (4) 4
amino acid sequence (3) 3
catalysis (3) 3
crystal-structure (3) 3
dehydrogenase (3) 3
delta-3-oxosteroid 5-beta-reductase (3) 3
delta-4-3-oxosteroid 5-beta-reductase (3) 3
expressed enzyme (3) 3
identification (3) 3
liver - enzymology (3) 3
molecular sequence data (3) 3
oxidoreductases - metabolism (3) 3
protein (3) 3
purification (3) 3
rats (3) 3
steroid hormones (3) 3
3-alpha-hydroxysteroid dehydrogenase (2) 2
aldo-keto reductase (2) 2
aldo–keto reductase (2) 2
apparent mineralocorticoid excess (2) 2
article (2) 2
base sequence (2) 2
bile acid biosynthesis (2) 2
bile-acid biosynthesis (2) 2
bile-acid synthesis (2) 2
biophysics (2) 2
cloning (2) 2
cortisol metabolism (2) 2
degradation (2) 2
dihydrodiol dehydrogenase (2) 2
enzyme (2) 2
essential-hypertension (2) 2
gastroenterology & hepatology (2) 2
human (2) 2
human aldose reductase (2) 2
hydrogen-ion concentration (2) 2
kinetics (2) 2
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messenger-rna (2) 2
molecular weight (2) 2
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nadp - metabolism (2) 2
oxidoreductases - chemistry (2) 2
oxidoreductases - isolation & purification (2) 2
point mutation (2) 2
proteins (2) 2
quantitation (2) 2
reductase (2) 2
region (2) 2
steroid hormone (2) 2
steroid metabolism (2) 2
steroids (2) 2
08 hydrogen (1) 1
11-beta-hydroxysteroid dehydrogenase (1) 1
11-beta-hydroxysteroid dehydrogenase type-1 (1) 1
20-alpha-hydroxysteroid dehydrogenase (1) 1
3-alpha-hydroxysteroid dihydrodiol dehydrogenase (1) 1
3-hydroxysteroid dehydrogenases - chemistry (1) 1
3-hydroxysteroid dehydrogenases - genetics (1) 1
3-hydroxysteroid dehydrogenases - metabolism (1) 1
3-oxo-5-beta-steroid delta-4-dehydrogenase (1) 1
3-oxo-delta-steroid 5 beta-reductase (1) 1
5 alpha-dht (1) 1
5 alpha-reductase (1) 1
5 alpha-reductase type 1 (1) 1
5 alpha-reductase type 2 (1) 1
5 alpha-reductase type 3 (1) 1
5 beta-dht (1) 1
5α-dht (1) 1
5α-reductase type 1 (1) 1
5α-reductase type 2 (1) 1
5α-reductase type 3 (1) 1
5β-dht (1) 1
acid elongating system (1) 1
acid treatment (1) 1
active-site (1) 1
akr (1) 1
akr1d1 (1) 1
aldehyde reductase (1) 1
aldose reductase (1) 1
ammonium sulfate (1) 1
androgens (1) 1
androstenedione - metabolism (1) 1
antibodies, monoclonal - biosynthesis (1) 1
antibodies, monoclonal - chemistry (1) 1
beta-reductase deficiency (1) 1
bile acid (1) 1
bile acid deficiency (1) 1
bile acids (1) 1
bile acids and salts - biosynthesis (1) 1
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PLOS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1
Delta(4)-3-oxosteroid 5 beta-reductase is member D1 of the aldo-keto reductase family 1 (AKR1D1), which catalyzes 5 beta-reduction of molecules with a... 
DELTA-4-3-KETOSTEROID 5-BETA-REDUCTASE | MESSENGER-RNA | SALT EXPORT PUMP | MULTIDISCIPLINARY SCIENCES | FARNESOID-X-RECEPTOR | STEROID-METABOLISM | LIVER-DISEASE | CHOLESTEROL 7-ALPHA-HYDROXYLASE GENE | PRIMARY RAT HEPATOCYTES | INBORN ERROR | NUCLEAR RECEPTOR
Journal Article
STEROIDS, ISSN 0039-128X, 05/2014, Volume 83, pp. 17 - 26
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2009, Volume 301, Issue 1, pp. 191 - 198
Journal Article
STEROIDS, ISSN 0039-128X, 04/2008, Volume 73, Issue 4, pp. 417 - 423
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 09/1999, Volume 84, Issue 9, pp. 3316 - 3321
ABSTRACTCortisol is metabolized irreversibly by A-ring reductases (5α- and 5β-reductases) and reversibly (to cortisone) by 11β-hydroxysteroid dehydrogenases... 
POLYCYSTIC-OVARY-SYNDROME | APPARENT MINERALOCORTICOID EXCESS | DELTA-4-3-KETOSTEROID 5-BETA-REDUCTASE | GROWTH-HORMONE | MESSENGER-RNA | RAT | IN-VIVO | ENDOCRINOLOGY & METABOLISM | ESSENTIAL-HYPERTENSION | STEROID 5-ALPHA-REDUCTASE | INSULIN SENSITIVITY
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 1990, Volume 37, Issue 5, pp. 717 - 724
Journal Article
HEPATOLOGY, ISSN 0270-9139, 01/1998, Volume 27, Issue 1, pp. 100 - 107
We recently identified Delta(4)-3-ketosteroid-5 beta-reductase as the 37 kd liver protein which is highly susceptible to acetaldehyde modification in rats... 
FAT-STORING CELLS | MODIFIED EPITOPES | DELTA-4-3-KETOSTEROID 5-BETA-REDUCTASE | GENE-EXPRESSION | HEPATIC LIPOCYTES | KUPFFER CELLS | ETHANOL | BILE-ACID BIOSYNTHESIS | CHENODEOXYCHOLIC ACID | GASTROENTEROLOGY & HEPATOLOGY | INBORN ERROR
Journal Article
JOURNAL OF HEPATOLOGY, ISSN 0168-8278, 02/1998, Volume 28, Issue 2, pp. 270 - 279
Background / Aims: Urinary 3-oxo-Delta(4) bile acids have been detected in infants wh ultimately died of liver disease. We used qualitative and quantitative... 
CHOLIC-ACID | DELTA-3-OXOSTEROID 5-BETA-REDUCTASE DEFICIENCY | HUMAN BIOLOGICAL-FLUIDS | infant | DELTA-4-3-OXOSTEROID 5-BETA-REDUCTASE | INBORN ERROR | EARLY LIFE | DELTA-4-3-KETOSTEROID 5-BETA-REDUCTASE | ketonic bile acid | METABOLISM | cholestasis | UNUSUAL BILE-ACIDS | LIVER | 3-oxo-Delta-steroid 5 beta-reductase | GASTROENTEROLOGY & HEPATOLOGY
Journal Article
EUROPEAN JOURNAL OF BIOCHEMISTRY, ISSN 0014-2956, 01/1994, Volume 219, Issue 1-2, pp. 357 - 363
The enzyme Delta(4)-3-oxosteroid 5 beta-reductase (3-oxo-5 beta-steroid: NADP(+) oxidoreductase and 4,5 beta-dihydrocortisone: NADP(+) Delta 4-oxidoreductase)... 
RAT-LIVER | SEQUENCE-ANALYSIS | DELTA-4-3-KETOSTEROID 5-BETA-REDUCTASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PURIFICATION | DEGRADATION | MOLECULAR-CLONING | BILE-ACID BIOSYNTHESIS | IDENTIFICATION | DELTA-4-3-OXOSTEROID 5-BETA-REDUCTASE | DEHYDROGENASE
Journal Article
BBA - Gene Structure and Expression, ISSN 0167-4781, 2001, Volume 1517, Issue 2, pp. 228 - 235
Journal Article
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