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Green Chemistry, ISSN 1463-9262, 2017, Volume 19, Issue 15, pp. 3574 - 3584
A efficient and concise one-pot procedure has been developed for the synthesis of highly functional morphan derivatives 3 based on diastereoselective double... 
ROUTE | GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY | SPIROOXINDOLE DERIVATIVES | ANTAGONIST | MONOACETALS | ONE-POT SYNTHESIS | DIELS-ALDER CYCLOADDITIONS | CONSTRUCTION | REGIOSELECTIVE SYNTHESIS | OPIOID DELTA-RECEPTOR | CHEMISTRY, MULTIDISCIPLINARY | CASCADE REACTION
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 11/2013, Volume 56, Issue 21, pp. 8826 - 8833
In previous studies we reported that addition of 7 alpha-acylamino groups to N-phenylpropyl-4 beta-methyl-5-(3-hydroxyphenyl)morphan (4) led to compounds that... 
FEAR | CHEMISTRY, MEDICINAL | KAPPA | DELTA-RECEPTOR | RATS | ALVIMOPAN | HIGHLY POTENT | RECEPTOR ANTAGONIST | DISCOVERY
Journal Article
Physiology & Behavior, ISSN 0031-9384, 2005, Volume 85, Issue 5, pp. 519 - 523
The present study was designed to examine the effects of μ- and δ-opioid receptor ligands on feeding behavior in meat-type chicks. Intracerebroventricular... 
Intracerebroventricular injection | Delta receptor | Mu receptor | Food intake | Chick
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 01/2012, Volume 20, Issue 2, pp. 949 - 961
The previously reported morphinan derivative SN-28 showed high selectivity and agonist activity for the delta opioid receptor. In the course of examining the... 
CHEMISTRY, MEDICINAL | NALTRINDOLE | TERTIARY-AMINES | BIOCHEMISTRY & MOLECULAR BIOLOGY | Opioid | DRUG DESIGN | CHEMISTRY, ORGANIC | Naltrexone | Analgesics | LIGANDS | delta Receptor | PHARMACOLOGY | KAPPA-AGONIST | SELECTIVITY | ANTAGONIST ACTIVITIES | MESSAGE ADDRESS CONCEPT
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 10/2015, Volume 292, pp. 95 - 101
The molecular mechanisms underlying the susceptibility or resilience to trauma-related disorders remain incompletely understood. Opioids modulate emotional... 
Animal models | Posttraumatic stress disorder | Delta receptor | Amygdala | Opioids | Fear conditioning | NOR-BINALTORPHIMINE | LEARNED FEAR | ANXIETY | MORPHINE | POTENTIATED STARTLE | DISORDERS | POSTTRAUMATIC-STRESS | NEUROSCIENCES | BEHAVIORAL SCIENCES | MICE | RECEPTORS | BRAIN | Gene expression | Laws, regulations and rules | Animal behavior | Genes | Analysis | Post-traumatic stress disorder
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2015, Volume 25, Issue 23, pp. 5532 - 5535
Journal Article
Journal Article