Neurology, ISSN 0028-3878, 08/2013, Volume 81, Issue 6, pp. 528 - 533
OBJECTIVE:To determine whether anemia is associated with incident dementia in older adults. METHODS:We studied 2,552 older adults (mean age 76.1 years; 38.9%...
MORTALITY | ALZHEIMER-DISEASE | CARDIOVASCULAR HEALTH | ERYTHROPOIETIN | COGNITIVE IMPAIRMENT | COHORT | PREVALENCE | OUTCOMES | HEMOGLOBIN CONCENTRATION | CLINICAL NEUROLOGY | DECLINE | Prospective Studies | Dementia - psychology | Follow-Up Studies | Anemia - epidemiology | Humans | Risk Factors | Anemia - diagnosis | Anemia - psychology | Aging - psychology | Dementia - diagnosis | Male | Dementia - epidemiology | Aging - physiology | Female | Aged | Health Status | Body Composition - physiology | Cohort Studies | 150
MORTALITY | ALZHEIMER-DISEASE | CARDIOVASCULAR HEALTH | ERYTHROPOIETIN | COGNITIVE IMPAIRMENT | COHORT | PREVALENCE | OUTCOMES | HEMOGLOBIN CONCENTRATION | CLINICAL NEUROLOGY | DECLINE | Prospective Studies | Dementia - psychology | Follow-Up Studies | Anemia - epidemiology | Humans | Risk Factors | Anemia - diagnosis | Anemia - psychology | Aging - psychology | Dementia - diagnosis | Male | Dementia - epidemiology | Aging - physiology | Female | Aged | Health Status | Body Composition - physiology | Cohort Studies | 150
Journal Article
Acta Psychiatrica Scandinavica, ISSN 0001-690X, 04/2010, Volume 121, Issue 4, pp. 260 - 272
Luck T, Riedel-Heller SG, Luppa M, Wiese B, Wollny A, Wagner M, Bickel H, Weyerer S, Pentzek M, Haller F, Moesch E, Werle J, Eisele M, Maier W, van den Bussche...
apoE ε4 allele | risk factors | mild cognitive impairment | incidence | ApoE 4 allele | Mild cognitive impairment | Risk factors | Incidence | DSM-III-R | NEUROFIBRILLARY TANGLES | PSYCHIATRY | CLINICALLY USEFUL CONCEPT | ALZHEIMERS-DISEASE | TOTAL CHOLESTEROL | ELDERLY SUBJECTS | BLOOD-PRESSURE | APOLIPOPROTEIN-E | SUBJECTIVE MEMORY IMPAIRMENT | VISION IMPAIRMENT | apoE epsilon 4 allele | Apolipoprotein E4 - genetics | Age Factors | Vascular Diseases - complications | Humans | Male | Cognition | Dementia - epidemiology | Memory Disorders - complications | Vascular Diseases - epidemiology | Cognition Disorders - prevention & control | Cognition Disorders - etiology | Aged, 80 and over | Female | Memory Disorders - epidemiology | Risk Factors | Cognition Disorders - genetics | Dementia - complications | Family Practice | Alleles | Sex Factors | Aged | Cognition Disorders - epidemiology | Longitudinal Studies | Germany | Family medicine | Physicians (General practice) | Apolipoproteins | Public health | Geriatric psychology | Cognition & reasoning | Older people | Gender | Age | Dementia
apoE ε4 allele | risk factors | mild cognitive impairment | incidence | ApoE 4 allele | Mild cognitive impairment | Risk factors | Incidence | DSM-III-R | NEUROFIBRILLARY TANGLES | PSYCHIATRY | CLINICALLY USEFUL CONCEPT | ALZHEIMERS-DISEASE | TOTAL CHOLESTEROL | ELDERLY SUBJECTS | BLOOD-PRESSURE | APOLIPOPROTEIN-E | SUBJECTIVE MEMORY IMPAIRMENT | VISION IMPAIRMENT | apoE epsilon 4 allele | Apolipoprotein E4 - genetics | Age Factors | Vascular Diseases - complications | Humans | Male | Cognition | Dementia - epidemiology | Memory Disorders - complications | Vascular Diseases - epidemiology | Cognition Disorders - prevention & control | Cognition Disorders - etiology | Aged, 80 and over | Female | Memory Disorders - epidemiology | Risk Factors | Cognition Disorders - genetics | Dementia - complications | Family Practice | Alleles | Sex Factors | Aged | Cognition Disorders - epidemiology | Longitudinal Studies | Germany | Family medicine | Physicians (General practice) | Apolipoproteins | Public health | Geriatric psychology | Cognition & reasoning | Older people | Gender | Age | Dementia
Journal Article
Annals of Neurology, ISSN 0364-5134, 05/2007, Volume 61, Issue 5, pp. 403 - 410
Objective Atherosclerosis has been implicated in the development of dementia and its major subtypes, Alzheimer's disease and vascular dementia. However,...
INTIMA-MEDIA THICKNESS | SURVIVAL | WHITE-MATTER LESIONS | COGNITIVE DECLINE | VASCULAR DEMENTIA | SILENT BRAIN INFARCTS | ALZHEIMERS-DISEASE | MENTAL STATE | ROTTERDAM | NEUROSCIENCES | BLOOD-PRESSURE | CLINICAL NEUROLOGY | Data Interpretation, Statistical | Prospective Studies | Dementia - psychology | Follow-Up Studies | Humans | Netherlands - epidemiology | Risk Factors | Atherosclerosis - complications | Dementia - diagnosis | Genotype | Male | Risk | Dementia - epidemiology | Atherosclerosis - epidemiology | Neuropsychological Tests | Atherosclerosis - diagnostic imaging | Carotid Arteries - diagnostic imaging | Apolipoproteins E - genetics | Ultrasonography | Female | Population | Aged | Cohort Studies
INTIMA-MEDIA THICKNESS | SURVIVAL | WHITE-MATTER LESIONS | COGNITIVE DECLINE | VASCULAR DEMENTIA | SILENT BRAIN INFARCTS | ALZHEIMERS-DISEASE | MENTAL STATE | ROTTERDAM | NEUROSCIENCES | BLOOD-PRESSURE | CLINICAL NEUROLOGY | Data Interpretation, Statistical | Prospective Studies | Dementia - psychology | Follow-Up Studies | Humans | Netherlands - epidemiology | Risk Factors | Atherosclerosis - complications | Dementia - diagnosis | Genotype | Male | Risk | Dementia - epidemiology | Atherosclerosis - epidemiology | Neuropsychological Tests | Atherosclerosis - diagnostic imaging | Carotid Arteries - diagnostic imaging | Apolipoproteins E - genetics | Ultrasonography | Female | Population | Aged | Cohort Studies
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 05/2018, Volume 14, Issue 5, pp. 601 - 609
Higher midlife body mass index (BMI) is suggested to increase the risk of dementia, but weight loss during the preclinical dementia phase may mask such...
Body mass index | Obesity | Cohort study | Bias | Dementia | INCIDENT DEMENTIA | METAANALYSIS | ALZHEIMERS-DISEASE | LATE-LIFE | FOLLOW-UP | CLINICAL NEUROLOGY | MIDLIFE | POPULATION-BASED COHORT | CORONARY-HEART-DISEASE | WEIGHT | Body Mass Index | Data Interpretation, Statistical | Global Health | Obesity - complications | Humans | Middle Aged | Risk Factors | Male | Dementia - etiology | Time Factors | Weight Loss - physiology | Female | Aged | Cohort Studies | Risk factors | cohort study | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | body mass index | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Individ och samhälle VIDSOC | Individual and Society VIDSOC | bias | dementia | obesity | Health Sciences
Body mass index | Obesity | Cohort study | Bias | Dementia | INCIDENT DEMENTIA | METAANALYSIS | ALZHEIMERS-DISEASE | LATE-LIFE | FOLLOW-UP | CLINICAL NEUROLOGY | MIDLIFE | POPULATION-BASED COHORT | CORONARY-HEART-DISEASE | WEIGHT | Body Mass Index | Data Interpretation, Statistical | Global Health | Obesity - complications | Humans | Middle Aged | Risk Factors | Male | Dementia - etiology | Time Factors | Weight Loss - physiology | Female | Aged | Cohort Studies | Risk factors | cohort study | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | body mass index | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Individ och samhälle VIDSOC | Individual and Society VIDSOC | bias | dementia | obesity | Health Sciences
Journal Article
Neurology, ISSN 0028-3878, 09/2014, Volume 83, Issue 10, pp. 920 - 928
OBJECTIVE:To determine whether low vitamin D concentrations are associated with an increased risk of incident all-cause dementia and Alzheimer disease....
COGNITIVE DECLINE | METAANALYSIS | EVENTS | AMYLOID-BETA | D DEFICIENCY | 25-HYDROXYVITAMIN D CONCENTRATION | D-RECEPTOR | HEALTH | CLINICAL NEUROLOGY | IMPAIRMENT | Alzheimer Disease - etiology | United States - epidemiology | Follow-Up Studies | Vitamin D Deficiency - complications | Humans | Risk Factors | Proportional Hazards Models | Male | Dementia - epidemiology | Incidence | Vitamin D - blood | Dementia - etiology | Vitamin D Deficiency - blood | Vitamin D Deficiency - epidemiology | Alzheimer Disease - epidemiology | Female | Vitamin D - analogs & derivatives | Aged | Dementia - blood | Alzheimer Disease - blood
COGNITIVE DECLINE | METAANALYSIS | EVENTS | AMYLOID-BETA | D DEFICIENCY | 25-HYDROXYVITAMIN D CONCENTRATION | D-RECEPTOR | HEALTH | CLINICAL NEUROLOGY | IMPAIRMENT | Alzheimer Disease - etiology | United States - epidemiology | Follow-Up Studies | Vitamin D Deficiency - complications | Humans | Risk Factors | Proportional Hazards Models | Male | Dementia - epidemiology | Incidence | Vitamin D - blood | Dementia - etiology | Vitamin D Deficiency - blood | Vitamin D Deficiency - epidemiology | Alzheimer Disease - epidemiology | Female | Vitamin D - analogs & derivatives | Aged | Dementia - blood | Alzheimer Disease - blood
Journal Article
PLoS Medicine, ISSN 1549-1277, 03/2017, Volume 14, Issue 3, p. e1002251
Background Variation in the clinical manifestation of dementia has been associated with differences in cognitive reserve, although less is known about the...
POPULATION | MEDICINE, GENERAL & INTERNAL | BRAIN RESERVE | LEISURE ACTIVITIES | ALZHEIMERS-DISEASE | STYLE | EDUCATION | KUNGSHOLMEN-PROJECT | SOCIOECONOMIC-STATUS | APOLIPOPROTEIN-E | SWEDISH TWINS | Humans | Risk Factors | Dementia - diagnosis | Male | Dementia - epidemiology | Dementia - genetics | Sweden - epidemiology | Dementia - etiology | Aged, 80 and over | Cognitive Reserve | Female | Aged | Cohort Studies | Psychological aspects | Social classes | Physiological aspects | Development and progression | Cognition | Research | Risk factors | Dementia | Elderly people | Neurosciences | Correlation | Error analysis | Communities | Neurobiology | Cognitive ability | Risk | Apolipoprotein E | Education | Aging | Dementia disorders | Health risks | Socio-economic aspects | Exposure | Apolipoproteins | Carriers | Neurology | Brain research | Teaching methods | Life span | Recreation | Alleles | Adults | Alzheimers disease | Health risk assessment | Other Medical Sciences | Medical and Health Sciences | Gerontologi, medicinsk/hälsovetenskaplig inriktning | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | lifespan | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Annan medicin och hälsovetenskap | Gerontology, specialising in Medical and Health Sciences | dementia | work complexity | Health Sciences | life course
POPULATION | MEDICINE, GENERAL & INTERNAL | BRAIN RESERVE | LEISURE ACTIVITIES | ALZHEIMERS-DISEASE | STYLE | EDUCATION | KUNGSHOLMEN-PROJECT | SOCIOECONOMIC-STATUS | APOLIPOPROTEIN-E | SWEDISH TWINS | Humans | Risk Factors | Dementia - diagnosis | Male | Dementia - epidemiology | Dementia - genetics | Sweden - epidemiology | Dementia - etiology | Aged, 80 and over | Cognitive Reserve | Female | Aged | Cohort Studies | Psychological aspects | Social classes | Physiological aspects | Development and progression | Cognition | Research | Risk factors | Dementia | Elderly people | Neurosciences | Correlation | Error analysis | Communities | Neurobiology | Cognitive ability | Risk | Apolipoprotein E | Education | Aging | Dementia disorders | Health risks | Socio-economic aspects | Exposure | Apolipoproteins | Carriers | Neurology | Brain research | Teaching methods | Life span | Recreation | Alleles | Adults | Alzheimers disease | Health risk assessment | Other Medical Sciences | Medical and Health Sciences | Gerontologi, medicinsk/hälsovetenskaplig inriktning | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | lifespan | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Annan medicin och hälsovetenskap | Gerontology, specialising in Medical and Health Sciences | dementia | work complexity | Health Sciences | life course
Journal Article
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ISSN 0735-1097, 05/2019, Volume 73, Issue 20, pp. 2596 - 2603
Until recently, intraindividual visit-to-visit variability of cardiovascular risk factors has been dismissed as random fluctuation. This simplistic concept was...
blood pressure | LIPID-LOWERING TREATMENT | heart rate | TARGET-ORGAN DAMAGE | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | BLOOD-PRESSURE VARIABILITY | BODY-WEIGHT VARIABILITY | PROGNOSTIC VALUE | body weight | ALL-CAUSE MORTALITY | DENSITY-LIPOPROTEIN CHOLESTEROL | HEART-RATE-VARIABILITY | glycemia | mortality | cholesterol | VISIT-TO-VISIT | Heart failure | Enzymes | Medical colleges | Calcium channels | Low density lipoproteins | Mortality | Body weight | Glycosylated hemoglobin | Risk factors | Heart attack | Cardiovascular agents | Stroke (Disease) | Heart beat | Chronic kidney failure | Electrocardiogram | Electrocardiography | Cardiology | Dementia | End-stage renal disease | Stroke | Heart attacks | Variability | Coronary artery | Health risks | Variations | Cardiovascular disease | Risk analysis | Coronary artery disease | Cholesterol | Heart rate | Elevation | Renal failure | Dementia disorders | Blood pressure | Kidney diseases | Cardiovascular diseases | Health risk assessment | Heart diseases
blood pressure | LIPID-LOWERING TREATMENT | heart rate | TARGET-ORGAN DAMAGE | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | BLOOD-PRESSURE VARIABILITY | BODY-WEIGHT VARIABILITY | PROGNOSTIC VALUE | body weight | ALL-CAUSE MORTALITY | DENSITY-LIPOPROTEIN CHOLESTEROL | HEART-RATE-VARIABILITY | glycemia | mortality | cholesterol | VISIT-TO-VISIT | Heart failure | Enzymes | Medical colleges | Calcium channels | Low density lipoproteins | Mortality | Body weight | Glycosylated hemoglobin | Risk factors | Heart attack | Cardiovascular agents | Stroke (Disease) | Heart beat | Chronic kidney failure | Electrocardiogram | Electrocardiography | Cardiology | Dementia | End-stage renal disease | Stroke | Heart attacks | Variability | Coronary artery | Health risks | Variations | Cardiovascular disease | Risk analysis | Coronary artery disease | Cholesterol | Heart rate | Elevation | Renal failure | Dementia disorders | Blood pressure | Kidney diseases | Cardiovascular diseases | Health risk assessment | Heart diseases
Journal Article
JAMA Neurology, ISSN 2168-6149, 10/2017, Volume 74, Issue 10, pp. 1246 - 1254
IMPORTANCE: Vascular risk factors have been associated with cognitive decline. Midlife exposure to these factors may be most important in conferring late-life...
ALLELE | DIAGNOSIS | ALZHEIMERS-DISEASE | ABILITY | SEX | LIFE COGNITIVE FUNCTION | HISPANICS | AFRICAN-AMERICANS | EDUCATION | BLOOD-PRESSURE | CLINICAL NEUROLOGY | Residence Characteristics | Age Factors | Humans | Middle Aged | Risk Factors | European Continental Ancestry Group | Male | Dementia - epidemiology | Vascular Diseases - epidemiology | Atherosclerosis - epidemiology | Incidence | Adult | Female | Aged | African Continental Ancestry Group | Cognition Disorders - epidemiology | Cohort Studies | Online First | Original Investigation | Research
ALLELE | DIAGNOSIS | ALZHEIMERS-DISEASE | ABILITY | SEX | LIFE COGNITIVE FUNCTION | HISPANICS | AFRICAN-AMERICANS | EDUCATION | BLOOD-PRESSURE | CLINICAL NEUROLOGY | Residence Characteristics | Age Factors | Humans | Middle Aged | Risk Factors | European Continental Ancestry Group | Male | Dementia - epidemiology | Vascular Diseases - epidemiology | Atherosclerosis - epidemiology | Incidence | Adult | Female | Aged | African Continental Ancestry Group | Cognition Disorders - epidemiology | Cohort Studies | Online First | Original Investigation | Research
Journal Article
Journal of the American Geriatrics Society, ISSN 0002-8614, 12/2016, Volume 64, Issue 12, pp. 2528 - 2532
Objectives To identify clinical correlates of person‐centered fall risk awareness and their validity for predicting falls. Design Prospective cohort study....
epidemiology | falls | aging | PERCEPTION | COMPLAINTS | MEMORY | OLDER-ADULTS | PREVENTION | GERONTOLOGY | GERIATRICS & GERONTOLOGY | Geriatric Assessment | New York | Prospective Studies | Risk Assessment | Awareness | Humans | Risk Factors | Accidental Falls - statistics & numerical data | Female | Male | Surveys and Questionnaires | Aged | Falls (Accidents) | Epidemiology | Risk factors | Dementia | Falls | Older people
epidemiology | falls | aging | PERCEPTION | COMPLAINTS | MEMORY | OLDER-ADULTS | PREVENTION | GERONTOLOGY | GERIATRICS & GERONTOLOGY | Geriatric Assessment | New York | Prospective Studies | Risk Assessment | Awareness | Humans | Risk Factors | Accidental Falls - statistics & numerical data | Female | Male | Surveys and Questionnaires | Aged | Falls (Accidents) | Epidemiology | Risk factors | Dementia | Falls | Older people
Journal Article
JAMA Psychiatry, ISSN 2168-622X, 06/2015, Volume 72, Issue 6, pp. 612 - 619
IMPORTANCE Although depression and type 2 diabetes mellitus (DM) may independently increase the risk for dementia, no studies have examined whether the risk...
MORTALITY | REGISTER | COLLABORATIVE CARE | COGNITIVE DECLINE | METAANALYSIS | PSYCHIATRY | ALZHEIMERS-DISEASE | SECONDARY CARE | DISORDERS | MAJOR DEPRESSION | PREVALENCE | Depression - epidemiology | Comorbidity | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | Dementia - epidemiology | Diabetes Mellitus, Type 2 - epidemiology | Denmark - epidemiology | Female | Registries | Aged | Cohort Studies | Complications and side effects | Cohort analysis | Usage | Depression, Mental | Diabetes | Risk factors | Dementia
MORTALITY | REGISTER | COLLABORATIVE CARE | COGNITIVE DECLINE | METAANALYSIS | PSYCHIATRY | ALZHEIMERS-DISEASE | SECONDARY CARE | DISORDERS | MAJOR DEPRESSION | PREVALENCE | Depression - epidemiology | Comorbidity | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Male | Dementia - epidemiology | Diabetes Mellitus, Type 2 - epidemiology | Denmark - epidemiology | Female | Registries | Aged | Cohort Studies | Complications and side effects | Cohort analysis | Usage | Depression, Mental | Diabetes | Risk factors | Dementia
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 10/2015, Volume 49, Issue 2, pp. 503 - 513
Background: Homocysteine has been identified as a potential risk factor for stroke, cerebral small-vessel diseases (SVD), and dementia. Objective: The present...
homocysteine | microbleeds | estimated glomerular filtration rate | vascular dementia | dementia | Alzheimer's disease | cerebral small-vessel disease | KIDNEY-DISEASE | ALZHEIMER-DISEASE | HYPERHOMOCYSTEINEMIA | HYPERINTENSITIES | COGNITIVE IMPAIRMENT | PATHOLOGY | NEUROSCIENCES | VITAMIN-B-12 | DIAGNOSTIC-CRITERIA | PLASMA HOMOCYSTEINE | ASSOCIATION | Predictive Value of Tests | Carotid Intima-Media Thickness | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Homocysteine - blood | Male | Cerebral Small Vessel Diseases - epidemiology | Dementia - epidemiology | Dementia - mortality | Incidence | Neuropsychological Tests | Magnetic Resonance Imaging | Cerebral Small Vessel Diseases - mortality | Statistics, Nonparametric | Cerebral Small Vessel Diseases - blood | Mental Status Schedule | Female | Aged | Dementia - blood | Longitudinal Studies
homocysteine | microbleeds | estimated glomerular filtration rate | vascular dementia | dementia | Alzheimer's disease | cerebral small-vessel disease | KIDNEY-DISEASE | ALZHEIMER-DISEASE | HYPERHOMOCYSTEINEMIA | HYPERINTENSITIES | COGNITIVE IMPAIRMENT | PATHOLOGY | NEUROSCIENCES | VITAMIN-B-12 | DIAGNOSTIC-CRITERIA | PLASMA HOMOCYSTEINE | ASSOCIATION | Predictive Value of Tests | Carotid Intima-Media Thickness | Humans | Middle Aged | Risk Factors | Proportional Hazards Models | Homocysteine - blood | Male | Cerebral Small Vessel Diseases - epidemiology | Dementia - epidemiology | Dementia - mortality | Incidence | Neuropsychological Tests | Magnetic Resonance Imaging | Cerebral Small Vessel Diseases - mortality | Statistics, Nonparametric | Cerebral Small Vessel Diseases - blood | Mental Status Schedule | Female | Aged | Dementia - blood | Longitudinal Studies
Journal Article