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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 6, pp. 2631 - 2646
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7411, pp. 404 - 408
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2011, Volume 133, Issue 24, pp. 9451 - 9456
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2016, Volume 59, Issue 4, pp. 1370 - 1387
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 17 - 30
and mutations occur frequently in gliomas and acute myeloid leukemia, leading to simultaneous loss and gain of activities in the production of α-ketoglutarate... 
BREAST-CANCER | TRANSCRIPTIONAL ACTIVITY | IDH2 MUTATIONS | ONCOLOGY | PROLYL HYDROXYLATION | INTEGRATED GENOMIC ANALYSIS | 2-OXOGLUTARATE OXYGENASES | ACUTE MYELOID-LEUKEMIA | HIF-ALPHA | HISTONE DEMETHYLATION | FAMILY | CELL BIOLOGY | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism
Journal Article
Nature, ISSN 0028-0836, 10/2014, Volume 514, Issue 7523, pp. 513 - 517
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2016, Volume 59, Issue 4, pp. 1357 - 1369
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2447 - 2456
Cardiac hypertrophy and failure are accompanied by a reprogramming of gene expression that involves transcription factors and chromatin remodeling enzymes.... 
HEART | MEDICINE, RESEARCH & EXPERIMENTAL | CARDIOMYOCYTE HYPERTROPHY | LYSINE DEMETHYLASES | MYOCARDIN | ACTIVATION | PROTEIN | CHROMATIN | DISEASE | GENE-EXPRESSION | PLASTICITY | Hypertrophy, Left Ventricular - enzymology | Heart Failure - enzymology | Humans | Jumonji Domain-Containing Histone Demethylases - physiology | Molecular Sequence Data | Male | Constriction, Pathologic - physiopathology | Histone Demethylases - genetics | Muscle Proteins - biosynthesis | Trans-Activators - physiology | Hypertrophy, Left Ventricular - pathology | Base Sequence | Ventricular Remodeling - genetics | Female | Heart Failure - etiology | Promoter Regions, Genetic | Cells, Cultured - drug effects | Serum Response Element | LIM Domain Proteins | Hypertrophy, Left Ventricular - etiology | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Gene Expression Regulation | Histone Demethylases - physiology | Intracellular Signaling Peptides and Proteins | Rats | Mice, Transgenic | Ventricular Remodeling - physiology | Constriction, Pathologic - complications | Jumonji Domain-Containing Histone Demethylases - genetics | Muscle Proteins - genetics | Aortic Diseases - physiopathology | Animals | Myocytes, Cardiac - drug effects | Aortic Diseases - complications | Myocytes, Cardiac - metabolism | Cells, Cultured - metabolism | Mice | Nuclear Proteins - physiology | Protein Processing, Post-Translational | Histone Demethylases - deficiency | Histones - metabolism | Methylation | Heart | Genetic transcription | Heart enlargement
Journal Article