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Genes & development, ISSN 0890-9369, 11/2013, Volume 27, Issue 21, pp. 2305 - 2319
Norrin is a cysteine-rich growth factor that is required for angiogenesis in the eye, ear, brain, and female reproductive organs. It functions as an atypical... 
Frizzled 4 | Wnt/β-catenin signaling | Cystine knot growth factor | Norrin structure | Low-density lipoprotein receptor-related protein 5/6 | Tetraspanin 12 | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Humans | Low Density Lipoprotein Receptor-Related Protein-5 - chemistry | Eye Proteins - chemistry | Crystallography, X-Ray | Transforming Growth Factor beta - chemistry | Low Density Lipoprotein Receptor-Related Protein-6 - chemistry | Nerve Tissue Proteins - chemistry | Frizzled Receptors - chemistry | HEK293 Cells | Maltose-Binding Proteins - chemistry | Eye Proteins - genetics | Protein Stability | Tetraspanins - metabolism | Binding Sites | Dimerization | Protein Structure, Tertiary | Signal Transduction | Frizzled Receptors - metabolism | Models, Molecular | Maltose-Binding Proteins - metabolism | Nerve Tissue Proteins - genetics | beta Catenin - metabolism | Nerve Tissue Proteins - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | Animals | Eye Proteins - metabolism | Low Density Lipoprotein Receptor-Related Protein-5 - metabolism | Protein Binding | Mice | COS Cells | Index Medicus | low-density lipoprotein receptor-related protein 5 | tetraspanin 12 | β-catenin signaling | Research Paper | Wnt | cystine knot growth factor
Journal Article
Nature communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 365 - 365
Wnt-induced β-catenin-mediated transcription is a driving force for stem cell self-renewal during adult tissue homeostasis. Enhanced Wnt receptor expression... 
Low Density Lipoprotein Receptor-Related Protein-6/antagonists & inhibitors | Cell Proliferation | Humans | Crystallography, X-Ray | Journal Article | Single-Domain Antibodies/chemistry | Intestine, Small/cytology | HEK293 Cells | Transcription, Genetic | Cell Differentiation | Protein Interaction Domains and Motifs | beta Catenin/genetics | Binding Sites | Stem Cells/cytology | Wnt3A Protein/genetics | Fibroblasts/cytology | Gene Expression Regulation | Models, Molecular | Animals | Protein Conformation, beta-Strand | Research Support, Non-U.S. Gov't | Cell Line, Tumor | Protein Binding | Low Density Lipoprotein Receptor-Related Protein-5/antagonists & inhibitors | Mice | Organoids/cytology | Ubiquitin-Protein Ligases/genetics | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Wnt3A Protein - metabolism | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Single-Domain Antibodies - metabolism | Low Density Lipoprotein Receptor-Related Protein-5 - chemistry | Stem Cells - cytology | Low Density Lipoprotein Receptor-Related Protein-6 - chemistry | Stem Cells - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 - genetics | Organoids - metabolism | Low Density Lipoprotein Receptor-Related Protein-5 - antagonists & inhibitors | Fibroblasts - metabolism | Wnt3A Protein - genetics | Organoids - cytology | Ubiquitin-Protein Ligases - metabolism | Low Density Lipoprotein Receptor-Related Protein-6 - antagonists & inhibitors | beta Catenin - metabolism | beta Catenin - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | Intestine, Small - cytology | Single-Domain Antibodies - chemistry | Fibroblasts - drug effects | Intestine, Small - drug effects | Low Density Lipoprotein Receptor-Related Protein-5 - metabolism | Organoids - drug effects | Stem Cells - drug effects | Fibroblasts - cytology | Intestine, Small - metabolism | Single-Domain Antibodies - genetics | Ubiquitin-Protein Ligases - genetics | Uncertainty | Organoids | Animal behavior | Neural networks | Circuits | Stem cells | Inactivation | Structural analysis | Index Medicus
Journal Article
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 04/2012, Volume 287, Issue 15, pp. 12016 - 12026
Journal Article