X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
deoxyguanosine - analogs & derivatives (646) 646
humans (606) 606
index medicus (579) 579
animals (550) 550
oxidative stress (489) 489
deoxyguanosine - metabolism (397) 397
male (376) 376
biochemistry & molecular biology (322) 322
dna damage (320) 320
rats (238) 238
female (226) 226
mice (209) 209
dna (188) 188
apoptosis (184) 184
oxidative stress - drug effects (173) 173
deoxyguanosine (171) 171
toxicology (139) 139
expression (135) 135
antioxidants (130) 130
cell biology (130) 130
oncology (124) 124
deoxyguanosine kinase (115) 115
cancer (114) 114
reactive oxygen species - metabolism (112) 112
cells (108) 108
research (108) 108
deoxyribonucleic acid--dna (106) 106
reactive oxygen species (106) 106
adult (105) 105
rodents (105) 105
enzymes (104) 104
analysis (103) 103
middle aged (102) 102
phosphorylation (101) 101
pharmacology & pharmacy (98) 98
dna-damage (96) 96
damage (95) 95
mutation (94) 94
activation (92) 92
proteins (91) 91
rats, sprague-dawley (90) 90
stress (89) 89
inflammation (86) 86
cell line (85) 85
deoxyguanosine - analysis (85) 85
immunohistochemistry (85) 85
in-vitro (85) 85
apoptosis - drug effects (83) 83
deoxyguanosine - pharmacology (83) 83
genetics & heredity (83) 83
medicine (83) 83
endocrinology & metabolism (82) 82
kinases (82) 82
cells, cultured (81) 81
dna repair (81) 81
gene expression (81) 81
article (78) 78
antioxidants - pharmacology (76) 76
dna damage - drug effects (76) 76
metabolism (75) 75
mitochondria (75) 75
kinetics (73) 73
research article (73) 73
oxidation-reduction (72) 72
multidisciplinary sciences (71) 71
aged (69) 69
physiological aspects (69) 69
cell line, tumor (68) 68
carcinogenesis (67) 67
disease models, animal (67) 67
deoxyguanosine - urine (66) 66
neurosciences (66) 66
time factors (66) 66
dna - metabolism (65) 65
base sequence (64) 64
mitochondrial dna (64) 64
toxicity (64) 64
dose-response relationship, drug (63) 63
hydrogen-peroxide (63) 63
phosphotransferases - metabolism (63) 63
deoxycytidine kinase (62) 62
deoxyguanosine - chemistry (62) 62
genetic aspects (62) 62
8-hydroxy-2'-deoxyguanosine (61) 61
health aspects (60) 60
diabetes (59) 59
free radicals (59) 59
liver (57) 57
oxidative dna-damage (57) 57
8-hydroxydeoxyguanosine (56) 56
biophysics (56) 56
gene (56) 56
genetic research (55) 55
glutathione (55) 55
lipid-peroxidation (55) 55
oxidative stress - physiology (54) 54
superoxide (53) 53
mice, inbred c57bl (52) 52
oxidative damage (52) 52
protein (52) 52
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Clinical Endocrinology, ISSN 0300-0664, 12/2019, Volume 91, Issue 6, pp. 900 - 903
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 15, pp. 4027 - 4032
Journal Article
Journal Article
The FEBS Journal, ISSN 1742-464X, 10/2012, Volume 279, Issue 20, pp. 3889 - 3897
Deoxyribonucleotides are the building blocks of DNA and can be synthesized via de novo and salvage pathways. Deoxyribonucleoside kinases (EC 2.7.1.145) salvage... 
deoxyribonucleoside kinase | nucleoside nucleotide metabolism | Arabidopsis | thymidine kinase | gene duplication | PURINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBSTRATE-SPECIFICITY | DEOXYCYTIDINE KINASE | ENZYME | PATHWAY | BIOSYNTHESIS | DEFICIENT | DEGRADATION | CELL-CYCLE | STRESS | Phosphorylation | Molecular Sequence Data | Substrate Specificity | Deoxyribonucleosides - metabolism | Thymidine Kinase - classification | Phylogeny | Isoenzymes - classification | Arabidopsis Proteins - metabolism | Deoxycytidine - metabolism | Isoenzymes - metabolism | Thymidine - metabolism | Multigene Family - genetics | Amino Acid Sequence | Arabidopsis Proteins - genetics | Biocatalysis | Thymidine Kinase - genetics | Isoenzymes - genetics | Arabidopsis - cytology | Cells, Cultured | Phosphotransferases (Alcohol Group Acceptor) - genetics | Deoxyadenosines - metabolism | Phosphotransferases (Alcohol Group Acceptor) - classification | Arabidopsis - metabolism | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Arabidopsis - genetics | Sequence Homology, Amino Acid | DNA, Bacterial - genetics | Thymidine Kinase - metabolism | Deoxyguanosine - metabolism | Mutagenesis, Insertional | Kinetics | Phosphates | Arabidopsis thaliana | Pyrimidines | Anopheles | DNA | Nucleosides | Physiological aspects | Phosphotransferases | Plant pathology | Mutation | Kinases | Molecular biology | Genomics | Deoxyribonucleic acid--DNA | Biological Sciences | Biochemistry and Molecular Biology | Biologi | Naturvetenskap | Natural Sciences | Biokemi och molekylärbiologi
Journal Article
Journal Article
Journal Article
Atherosclerosis, ISSN 0021-9150, 2005, Volume 183, Issue 2, pp. 259 - 267
In this study the effects of stable and intermittent high glucose concentrations on ICAM-1, VCAM-1 and E-selectin production, PKC activity and PKCβI, βII and δ... 
Adhesion molecules | PKC | Mitochondrial superoxide | Intermittent glucose | Endothelium | endothelium | OXIDATIVE STRESS | ACTIVATION | CIRCULATING ADHESION MOLECULES | BLOOD-GLUCOSE | ATHEROSCLEROSIS | MECHANISMS | intermittent glucose | DIABETES-MELLITUS | mitochondrial superoxide | HYPERGLYCEMIA | adhesion molecules | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | COMPLICATIONS | Endothelium, Vascular - cytology | Mitochondria - enzymology | Vascular Cell Adhesion Molecule-1 - drug effects | Gene Expression - drug effects | Humans | Glucose - administration & dosage | Dose-Response Relationship, Drug | RNA, Messenger - biosynthesis | E-Selectin - genetics | Protein Kinase C - metabolism | Intercellular Adhesion Molecule-1 - biosynthesis | E-Selectin - biosynthesis | Superoxides - metabolism | Intercellular Adhesion Molecule-1 - drug effects | Vascular Cell Adhesion Molecule-1 - genetics | E-Selectin - drug effects | Umbilical Veins - cytology | Deoxyguanosine - analogs & derivatives | Infant, Newborn | Enzyme-Linked Immunosorbent Assay | Protein Kinase C - drug effects | RNA, Messenger - genetics | Cells, Cultured | Blotting, Western | Blotting, Northern | Endothelium, Vascular - metabolism | Intercellular Adhesion Molecule-1 - genetics | Deoxyguanosine - metabolism | Vascular Cell Adhesion Molecule-1 - biosynthesis | Oxidative Stress - drug effects | In Vitro Techniques | Sweetening Agents - administration & dosage | Umbilical Veins - metabolism | Messenger RNA | Atherosclerosis | Superoxide | Glucose | Protein kinases | Dextrose | Porphyrins
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2007, Volume 568, Issue 1, pp. 242 - 247
This study aimed to investigate the effect of the Rho-kinase inhibitor fasudil on the development of diabetic nephropathy and clarify a contribution of the... 
Nephropathy | Rho | Rho-kinase | TGF-β | Diabetes | Statin | NAD(P)H oxidase | Fasudil | TGF-beta | REACTIVE OXYGEN | statin | fasudil | rho | nephropathy | rho-kinase | PHARMACOLOGY & PHARMACY | diabetes | EXPRESSION | Kidney Cortex - drug effects | Diabetes Mellitus, Experimental - drug therapy | Kidney Cortex - metabolism | Streptozocin | Cholesterol - blood | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Diabetic Nephropathies - drug therapy | Male | RNA, Messenger - metabolism | Fatty Acids, Monounsaturated - therapeutic use | rho-Associated Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | NADPH Oxidases - genetics | Albuminuria - metabolism | Blood Pressure - drug effects | Diabetes Mellitus, Experimental - metabolism | Deoxyguanosine - analogs & derivatives | Blood Glucose - analysis | Deoxyguanosine - urine | Diabetic Nephropathies - metabolism | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Intercellular Signaling Peptides and Proteins - genetics | Rats | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - therapeutic use | NADPH Oxidase 4 | Rats, Sprague-Dawley | Animals | Immediate-Early Proteins - genetics | Transforming Growth Factor beta - genetics | Protein Kinase Inhibitors - therapeutic use | Albuminuria - drug therapy | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Indoles - therapeutic use | Connective Tissue Growth Factor | Oxidases | Enzymes | RNA | Blood sugar | Diabetic nephropathies | Glucose | Transforming growth factors | Dextrose | Messenger RNA | Physiological aspects | Kidney diseases | Statins
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 06/2018, Volume 28, Issue 17, pp. 1543 - 1561
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2019, Volume 14, Issue 2, p. e0212065
Plasmodium falciparum thymidylate kinase (PfTMK) showed structural and catalytic distinctions from the host enzyme rendering it a hopeful antiprotozoal drug... 
ALPHA | THYMIDINE ANALOGS | MULTIDISCIPLINARY SCIENCES | DISCOVERY | Molecular dynamics | Plasmodium falciparum | Research | Chemical synthesis |