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Nature, ISSN 0028-0836, 01/2003, Volume 421, Issue 6921, pp. 436 - 440
The aesthetic appeal of the DNA double helix initially hindered notions of DNA mutation and repair, which would necessarily interfere with its pristine state.... 
DEOXYRIBONUCLEIC-ACID | CELLS | XERODERMA-PIGMENTOSUM | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | EUKARYOTES | HOMOLOG | DNA - genetics | DNA - chemistry | Neoplasms - genetics | DNA Repair | Mutagenesis - genetics | DNA - metabolism | DNA Damage | Evolution | Mutation | Molecular biology | Deoxyribonucleic acid | DNA
Journal Article
2006, ISBN 9780824759612, xxii, 845
Book
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2018, Volume 24, Issue 7, pp. 927 - 930
Here, we report that genome editing by CRISPR-Cas9 induces a p53-mediated DNA damage response and cell cycle arrest in immortalized human retinal pigment... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | REPAIR | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | EFFICIENCY | CELL BIOLOGY | CRISPR | p53 Protein | DNA damage | Homologous recombination | Editing | Homology | Retina | Genomes | Damage prevention | Retinal pigment epithelium | Cell cycle | Inhibition | Deoxyribonucleic acid--DNA
Journal Article
Journal Article
2007, ISBN 0387729739, 228
Book
Cold Spring Harbor Perspectives in Biology, ISSN 1943-0264, 07/2013, Volume 5, Issue 7, pp. a012567 - a012567
Under favorable conditions DNA can survive for thousands of years in the remains of dead organisms. The DNA extracted from such remains is invariably degraded... 
EXTRACTION | MISCODING LESIONS | SEQUENCES | DEOXYRIBONUCLEIC ACID | ENZYMATIC AMPLIFICATION | PATTERNS | DEGRADATION | BONE | INSIGHTS | REVEALS | CELL BIOLOGY | DNA - chemistry | DNA Damage | Deamination | Time Factors | Sequence Analysis, DNA | DNA Fragmentation | 011
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2017, Volume 118, Issue 11, pp. 3866 - 3874
FA is genotoxic and post‐translationally modified p53 leading to cell growth arrest and apoptosis of HepG2 cells. The results indicate that Ser‐15... 
p‐Ser‐15‐p53 | FUSARIC ACID | DNA DAMAGE | a‐K382‐p53 | POST‐TRANSLATIONAL MODIFICATIONS | p53 | a-K382-p53 | POST-TRANSLATIONAL MODIFICATIONS | p-Ser-15-p53 | DOMAIN | ACTIVATION | MECHANISM | PHOSPHORYLATION | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | CELL BIOLOGY | INHIBITION | HYPOTENSIVE AGENT | MYCOTOXIN | STRESS | Fusaric Acid - pharmacology | Protein Processing, Post-Translational - drug effects | Apoptosis - drug effects | Humans | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Tumor Suppressor Protein p53 - metabolism | Liver Neoplasms - pathology | Cell Proliferation - drug effects | DNA Damage | Carcinoma, Hepatocellular - metabolism | Hep G2 Cells | Ubiquitin | Cell death | DNA damage | Analysis | DNA | Genetic research | Histones | Genetic aspects | Hepatoma | Tumor proteins | Cancer | Cell proliferation | Cell culture | Histone deacetylase | Phosphorylation | Toxicity | p53 Protein | Genotoxicity | Hepatocellular carcinoma | Event-related potentials | Maize | Western blotting | Comet assay | Proteins | Fungi | Liver cancer | Ubiquitination | Protein folding | Fusaric acid | Post-translation | Acetylation | Damage | Deoxyribonucleic acid--DNA | Plants (botany) | MDM2 protein | Translation | Bioassay | Bioassays | Corn | Gene expression | Histone acetyltransferase | SIRT1 protein | Damage detection | Acids | Contaminants | Protein expression | Tumor suppressor genes | Apoptosis | Index Medicus
Journal Article
2006, ISBN 3540261206, xx, 523
The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent... 
DNA repair | Free radicals (Chemistry) | DNA damage | Chemistry, Organic | Life Sciences | Biochemistry, general | Life Sciences, general | Oncology | Molecular Medicine | Cell Biology | Organic Chemistry
Book
Nature Immunology, ISSN 1529-2908, 04/2019, Volume 20, Issue 4, pp. 420 - 432
Journal Article
JAMA, ISSN 0098-7484, 09/2015, Volume 314, Issue 11, pp. 1111 - 1112
One of the remarkable properties of nature's most remarkable molecule, DNA, is self-awareness: it can detect information about its own integrity and transmit... 
CELLS | MEDICINE, GENERAL & INTERNAL | Awards and Prizes | Biomedical Research | DNA Damage - physiology | DNA - physiology | Humans | DNA Repair - physiology | United States | DNA damage | Self-perception | Analysis | Genomics | Medical care | Research | Management | DNA repair | Deoxyribonucleic acid--DNA
Journal Article