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Cancer Cell, ISSN 1535-6108, 2010, Volume 18, Issue 5, pp. 485 - 498
Oncogene addiction is thought to occur cell autonomously. Immune effectors are implicated in the initiation and restraint of tumorigenesis, but their role in... 
BREAST-CANCER | ONCOLOGY | IFN-GAMMA | ANGIOGENIC SWITCH | THROMBOSPONDIN-1 | C-MYC | DEPENDENT INHIBITION | SENESCENCE | MYC INACTIVATION | ANTITUMOR IMMUNITY | CANCER-THERAPY
Journal Article
Journal of Physics D: Applied Physics, ISSN 0022-3727, 01/2018, Volume 51, Issue 4
Inactivation experiments were performed with Bacillus subtilis spores in a low pressure double inductively coupled plasma (DICP) system. Argon, nitrogen and... 
plasma sterilization | wavelength dependent sporicidal efficiency | inactivation experiments | spectroscopy | PHYSICS, APPLIED | BACTERIAL-SPORES | RADIATION | EXCISION-REPAIR | STERILIZATION | BACILLUS-SUBTILIS | PROTECTIVE ROLE | DNA | RESISTANCE | STRUCTURAL COMPONENTS
Journal Article
Radiation Physics and Chemistry, ISSN 0969-806X, 11/2016, Volume 128, pp. 112 - 117
Proteins, which have enzymatic activities play a fundamental role in the cell due to participation in most of biological processes. Oxidative-induced damage of... 
LDH | Ionizing radiation | Reactive oxygen species | Thiol-dependent enzymes | ADH | GAPDH | RESVERATROL | ACID | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | REACTIVITY | CHEMISTRY, PHYSICAL | CYSTEINE | PEPTIDE | RADIOLYSIS | INHIBITION | NUCLEAR SCIENCE & TECHNOLOGY | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | ALCOHOL-DEHYDROGENASE | Radiolysis | Oxidoreductases | Cells | Radiation | Hydrogen peroxide | Thiols | Amino acids | Superoxide
Journal Article
Science, ISSN 0036-8075, 10/2016, Volume 354, Issue 6310, pp. 343 - 347
Journal Article
Nature, ISSN 0028-0836, 04/2009, Volume 458, Issue 7240, pp. 894 - 898
Journal Article
Biochemistry, ISSN 0006-2960, 05/2018, Volume 57, Issue 18, pp. 2611 - 2622
The paralogues TRPVS and TRPV6 belong to the vanilloid subfamily of the transient receptor potential (TRP) superfamily of ion channels, and both play an... 
PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL DOMAIN | ION-CHANNEL | BINDING DOMAIN | EPITHELIAL CA2+ CHANNEL | GLUTAMATE-DECARBOXYLASE | TISSUE INHIBITOR | CA2+-DEPENDENT INACTIVATION | Calcium compounds | Calmodulin | Chemical properties
Journal Article
The Plant Cell, ISSN 1040-4651, 5/2013, Volume 25, Issue 5, pp. 1592 - 1608
CRK5 is a member of the Arabidopsis thaliana Ca2+/calmodulin-dependent kinase-related kinase family. Here, we show that inactivation of CRK5 inhibits primary... 
Endocytosis | RESEARCH ARTICLES | Epidermal cells | Plant roots | Auxins | Cell membranes | Gene expression regulation | Plants | Genetic mutation | Plant cells | Seedlings | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT-CELLS | TRAFFICKING | DEPENDENT PROTEIN-KINASE | BIOCHEMICAL-CHARACTERIZATION | P-GLYCOPROTEIN | PLANT SCIENCES | CELL BIOLOGY | EFFLUX | CALCIUM | BASIPETAL AUXIN TRANSPORT | THALIANA ROOTS | Arabidopsis - physiology | Phosphorylation | Molecular Sequence Data | Plant Roots - genetics | Green Fluorescent Proteins - genetics | Exocytosis | Arabidopsis Proteins - metabolism | Plant Roots - physiology | Plants, Genetically Modified | Gene Expression Regulation, Plant | Protein-Serine-Threonine Kinases - metabolism | Amino Acid Sequence | Green Fluorescent Proteins - metabolism | Arabidopsis Proteins - genetics | Plant Roots - metabolism | Indoleacetic Acids - metabolism | Electrophoresis, Polyacrylamide Gel | Protein-Serine-Threonine Kinases - genetics | Receptors, Cell Surface - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Arabidopsis - metabolism | Arabidopsis - genetics | Sequence Homology, Amino Acid | Cell Membrane - enzymology | Microscopy, Confocal | Gravitropism | Enzyme Activation | Mutation | Receptors, Cell Surface - genetics | Arabidopsis thaliana | Physiological aspects | Research | Health aspects | Phosphotransferases
Journal Article
Oncogene, ISSN 0950-9232, 03/2014, Volume 33, Issue 12, pp. 1538 - 1547
The accumulation of genetic and epigenetic alterations mediates colorectal cancer (CRC) formation by deregulating key signaling pathways in cancer cells. In... 
PTEN | Transforming growth factor-beta | Colon cancer | APC MUTATION | colon cancer | RECEPTOR-TYPE-II | MICROSATELLITE INSTABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | p21(Cip1) | CELL-PROLIFERATION | CELL BIOLOGY | transforming growth factor-beta | GENE | ONCOLOGY | PATHWAY | COLORECTAL-CANCER | GROWTH | GENETICS & HEREDITY | TUMOR-SUPPRESSOR | EXPRESSION | Cell Cycle - genetics | Protein-Serine-Threonine Kinases - deficiency | Colonic Neoplasms - genetics | Receptors, Transforming Growth Factor beta - genetics | Humans | Colonic Neoplasms - metabolism | Intestinal Mucosa - drug effects | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Cyclin-Dependent Kinases - antagonists & inhibitors | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | PTEN Phosphohydrolase - genetics | PTEN Phosphohydrolase - deficiency | Carcinogenesis - genetics | Protein-Serine-Threonine Kinases - genetics | Signal Transduction - genetics | Gene Knockout Techniques | Disease Progression | Carcinogenesis - drug effects | Animals | Signal Transduction - drug effects | Colonic Neoplasms - pathology | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Mutation | Cell Cycle - drug effects | Transforming Growth Factor beta - metabolism | Intestinal Mucosa - pathology | Receptors, Transforming Growth Factor beta - deficiency | Index Medicus | p21Cip1 | colorectal cancer | transforming growth factor beta
Journal Article
Journal Article
Science Signaling, ISSN 1945-0877, 03/2013, Volume 6, Issue 268, pp. ra20 - ra20
The clinical efficacy of tyrosine kinase inhibitors supports the dependence of distinct subsets of cancers on specific driver mutations for survival, a... 
LUNG ADENOCARCINOMAS | HER2 AMPLIFICATION | BREAST-CANCER CELLS | MITOCHONDRIAL APOPTOSIS | DEPENDENT CELL-DEATH | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | KINASE INHIBITORS | BH3 DOMAINS | FOXO TRANSCRIPTION FACTORS | MEMBRANE PERMEABILIZATION | CELL BIOLOGY | Immunohistochemistry | RNA, Small Interfering - genetics | MAP Kinase Signaling System - physiology | Humans | Receptor, ErbB-2 - metabolism | Apoptosis - genetics | Immunoblotting | Quinazolines | Oncogenes - physiology | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Bcl-2-Like Protein 11 | Biphenyl Compounds - pharmacology | Chromatin Immunoprecipitation | Nitrophenols - pharmacology | RNA Interference | Plasmids - genetics | Apoptosis Regulatory Proteins - genetics | Female | Membrane Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Oncogenes - genetics | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Piperazines - pharmacology | Apoptosis Regulatory Proteins - metabolism | Animals | Cell Line, Tumor | Signal Transduction - physiology | Mice | Gene Silencing - physiology | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
The EMBO Journal, ISSN 0261-4189, 05/2011, Volume 30, Issue 9, pp. 1742 - 1752
Journal Article
Biochemistry, ISSN 0006-2960, 05/2018, Volume 57, Issue 18, pp. 2623 - 2635
The transient receptor potential vanilloid channel subfamily member 5 (TRPVS) is a highly selective calcium ion channel predominately expressed in the kidney... 
BACKBONE DYNAMICS | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | TRPV5 CHANNEL | CHEMICAL-SHIFTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | EPITHELIAL CA2+ CHANNEL | PARATHYROID-HORMONE | PROTONLESS NMR-SPECTROSCOPY | CALMODULIN-BINDING | CA2+-DEPENDENT INACTIVATION | MOLECULAR-MECHANISMS | Calcium compounds | Chemical properties | Research | Structure | Calmodulin
Journal Article