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index medicus (470) 470
deubiquitinase (369) 369
humans (326) 326
ubiquitin (278) 278
animals (193) 193
ubiquitination (175) 175
cell biology (171) 171
biochemistry & molecular biology (159) 159
proteins (148) 148
cancer (143) 143
deubiquitinases (116) 116
apoptosis (107) 107
oncology (94) 94
ubiquitin - metabolism (90) 90
enzymes (89) 89
cell line, tumor (83) 83
nf-kappa-b (83) 83
mice (82) 82
activation (76) 76
ubiquitin thiolesterase - metabolism (76) 76
signal transduction (73) 73
degradation (71) 71
expression (67) 67
proteasome (65) 65
phosphorylation (63) 63
analysis (62) 62
mutation (62) 62
protein binding (62) 62
hek293 cells (59) 59
proteases (57) 57
endopeptidases - metabolism (56) 56
ubiquitin thiolesterase - genetics (56) 56
female (55) 55
male (55) 55
protein (55) 55
gene expression (52) 52
cell cycle (50) 50
ubiquitin-specific proteases - metabolism (48) 48
ubiquitin-protein ligases - metabolism (47) 47
health aspects (46) 46
cyld (43) 43
inhibition (43) 43
proteolysis (42) 42
research (42) 42
inflammation (41) 41
hela cells (40) 40
immunology (40) 40
models, molecular (40) 40
proteasome endopeptidase complex - metabolism (40) 40
binding (39) 39
kinases (39) 39
structural basis (38) 38
deubiquitinase bap1 (37) 37
small-molecule inhibitor (37) 37
tumor suppressor proteins - metabolism (37) 37
ligases (36) 36
multidisciplinary sciences (36) 36
endopeptidases - genetics (35) 35
deubiquitinating enzymes - metabolism (34) 34
tumor-suppressor (34) 34
biology (33) 33
cell proliferation (33) 33
specificity (33) 33
tumors (33) 33
biophysics (32) 32
chemistry, multidisciplinary (32) 32
pharmacology & pharmacy (32) 32
tumor suppressor proteins - genetics (32) 32
deoxyribonucleic acid--dna (30) 30
genetic aspects (30) 30
microbiology (30) 30
mutations (30) 30
ubiquitylation (30) 30
apoptosis - drug effects (29) 29
autophagy (29) 29
inhibitors (29) 29
mechanisms (29) 29
p53 (29) 29
proliferation (29) 29
cells (28) 28
gene-expression (28) 28
pathway (28) 28
antineoplastic agents - pharmacology (27) 27
dna repair (27) 27
genetics & heredity (27) 27
research paper (27) 27
transcription (27) 27
ubiquitin-proteasome system (27) 27
amino acid sequence (26) 26
chains (26) 26
complex (26) 26
cysteine (26) 26
deubiquitinating enzyme (26) 26
dna damage (26) 26
medicine, research & experimental (26) 26
physiological aspects (26) 26
ubiquitin - chemistry (26) 26
deubiquitinating enzymes (25) 25
e3 ligase (25) 25
gene expression regulation, neoplastic (25) 25
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Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 01/2010, Volume 17, Issue 1, pp. 25 - 34
  Protein ubiquitination is a reversible reaction, in which the ubiquitin chains are deconjugated by a family of deubiquitinases (DUBs). The presence of a... 
CYLD | NF-κB | tumor suppressor | deubiquitination | deubiquitinase
Journal Article
Oncotarget, ISSN 1949-2553, 12/2018, Volume 9, Issue 99, pp. 37276 - 37277
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 12/2019, Volume 29, Issue 11, pp. 3652 - 3663.e5
Linear ubiquitination has emerged as an important post-translational modification that regulates NF-κB activation, inflammation, and cell death in both immune... 
CYLD | cell death | inflammation | OTULIN | apoptosis | LUBAC | ubiquitin | deubiquitinase | necroptosis | DUSP14 | SPATA2 LINKS CYLD | K63 DEUBIQUITINASE | ACTIVATION | PHOSPHORYLATION | LINEAR UBIQUITIN | PHOSPHATASE | RIPK1 | NF-KAPPA-B | SIGNALING COMPLEX | CELL BIOLOGY
Journal Article
Nature immunology, ISSN 1529-2916, 2014, Volume 15, Issue 6, pp. 562 - 570
Journal Article
Theranostics, ISSN 1838-7640, 2019, Volume 9, Issue 14, pp. 4208 - 4220
Ubiquitin specific peptidase 5 (USP5) is a ubiquitous expressed deubiquitinating enzyme (DUB). It has been shown involved in DNA repair, apoptosis,... 
Journal Article
Chemical science (Cambridge), ISSN 2041-6539, 2019, Volume 10, Issue 44, pp. 10290 - 10296
Developing USP16-selective ubiquitin-based reagents to study USP16 and its related biology. Ubiquitination is a post-translational modification that is... 
CHEMICAL-SYNTHESIS | UBIQUITIN VARIANT INHIBITORS | DEUBIQUITINASE | CHEMISTRY, MULTIDISCIPLINARY | ENZYMES | PROBES
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 6, pp. 1619 - 1626.e5
Journal Article
Cell death and differentiation, ISSN 1476-5403, 2009, Volume 17, Issue 1, pp. 25 - 34
Protein ubiquitination is a reversible reaction, in which the ubiquitin chains are deconjugated by a family of deubiquitinases (DUBs). The presence of a large... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | DE-UBIQUITINATION | HPV E6 | tumor suppressor | CELL APOPTOSIS | deubiquitinase | NEGATIVE REGULATOR | CELL BIOLOGY | SEQUESTOSOME 1/P62 | CYLD | NF-kappa B | ENZYME CYLD | GENE | CYLINDROMATOSIS | deubiquitination | PAGETS-DISEASE | A20 | NF-κB
Journal Article
Analytical biochemistry, ISSN 0003-2697, 9/2013, Volume 440, Issue 1, pp. 71 - 77
Deubiquitinases (DUBs) play an important role in regulating the ubiquitin landscape of proteins. The DUB AMSH ( A ssociated M olecule with the SH 3 domain of... 
FRET | deubiquitinase assay | HTS | AMSH
Journal Article