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deubiquitylation (143) 143
index medicus (129) 129
humans (94) 94
biochemistry & molecular biology (88) 88
ubiquitin (53) 53
animals (51) 51
ubiquitination (51) 51
cell biology (42) 42
ubiquitylation (41) 41
ubiquitin - metabolism (34) 34
endopeptidases - metabolism (32) 32
protein binding (29) 29
ubiquitin thiolesterase - metabolism (28) 28
proteins (27) 27
endopeptidases - genetics (26) 26
complex (25) 25
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histones - metabolism (23) 23
mice (22) 22
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deubiquitinating enzyme (21) 21
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ubiquitin thiolesterase - genetics (19) 19
chromatin (17) 17
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article (16) 16
dna repair (15) 15
proteasome (15) 15
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ubiquitin-specific proteases - metabolism (15) 15
activation (14) 14
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binding (13) 13
cancer (13) 13
dna damage response (13) 13
expression (13) 13
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proteasome endopeptidase complex - metabolism (13) 13
ubiquitin-protein ligases - metabolism (13) 13
ubiquitination - physiology (13) 13
yeast (13) 13
apoptosis (12) 12
deubiquitination (12) 12
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hela cells (12) 12
phosphorylation (12) 12
protein structure, tertiary (12) 12
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protein synthesis and degradation (11) 11
protein transport (11) 11
saccharomyces-cerevisiae (11) 11
ubiquitin-protein ligases - genetics (11) 11
cell line, tumor (10) 10
crystal-structure (10) 10
crystallography, x-ray (10) 10
dna-binding proteins - metabolism (10) 10
endosomal sorting complexes required for transport - metabolism (10) 10
gene (10) 10
nuclear proteins - metabolism (10) 10
protein processing, post-translational (10) 10
research (10) 10
saccharomyces cerevisiae proteins - metabolism (10) 10
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ubiquitin-specific peptidase 7 (9) 9
ubp8 (9) 9
blotting, western (8) 8
chromatin - metabolism (8) 8
deubiquitinating enzymes (8) 8
drosophila proteins - metabolism (8) 8
gene expression regulation (8) 8
gene regulation (8) 8
multidisciplinary sciences (8) 8
nf-kappa-b (8) 8
polyubiquitin chains (8) 8
post-translational modification (8) 8
saga complex (8) 8
sequence homology, amino acid (8) 8
thiolester hydrolases - metabolism (8) 8
ubiquitin thiolesterase - chemistry (8) 8
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American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 07/2011, Volume 301, Issue 1, pp. F189 - F196
Journal Article
Endocrine Journal, ISSN 0918-8959, 2018
The molecular mechanism involved in the exocytosis of arginine vasopressin (AVP) is not fully known. Rabphilin-3A has been suggested as a novel autoantigen in... 
Rabphilin-3A | Deubiquitylation | Secretion | Vasopressin | Cullin-associated NEDD8-dissociated protein 1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2017, Volume 114, Issue 14, pp. e2872 - e2881
Journal Article
Journal of cell science, ISSN 0021-9533, 01/2019, Volume 132, Issue 2, p. jcs221663
Centriolar satellites are small cytoplasmic granules that play important roles in regulating the formation of centrosomes and primary cilia. Ubiquitylation of... 
Deubiquitylation | PCM1 | Centriolar satellites | Deubiquitylase | USP9X | LOCALIZATION | CILIOPATHIES | CILIUM | CENTROSOMAL PROTEIN | CELL BIOLOGY | GENE | INTERACTS | COMPONENT | MUTATIONS | CEP290 | DEUBIQUITINASE USP9X
Journal Article
Heart Rhythm, ISSN 1547-5271, 03/2012, Volume 9, Issue 3, pp. 440 - 448
Background: KCNQ1 (Kv7.1), together with its KCNE β subunits, plays a pivotal role both in the repolarization of cardiac tissue and in water and salt transport... 
Deubiquitylation | Membrane protein regulation | Ubiquitylation | Kv7.1 | minK | Potassium channels
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2019, Volume 294, Issue 34, pp. jbc.AC119.009977 - 12621
Microtubule-associated protein 1 light chain 3 α (LC3)/GABA type A receptor-associated protein (GABARAP) comprises a family of ubiquitin-like proteins involved... 
Index Medicus | cysteine protease | deconjugation | GABARAPL2 | autophagy | deubiquitylation (deubiquitination) | ubiquitin-conjugating enzyme (E2 enzyme) | ATG4B | post-translational modification | Atg8 | LC3ylation | Accelerated Communications
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2019, Volume 294, Issue 12, pp. 4572 - 4582
Chemoresistance is a leading obstacle in effective management of advanced prostate cancer (PCa). A better understanding of the molecular mechanisms involved in... 
ubiquitylation (ubiquitination) | pre-B cell leukemia homeobox-1 | prostate cancer | deubiquitylation (deubiquitination) | USP9x | apoptosis | cancer | cancer biology | drug resistance | protein degradation | TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | CHEMORESISTANCE
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 46, pp. 18747 - 18759
The expression of normal cellular prion protein (PrP) is required for the pathogenesis of prion diseases. However, the physiological functions of PrP remain... 
Index Medicus | NF-κB signaling | CYLD | tumor necrosis factor (TNF) | TNFα | deubiquitylation (deubiquitination) | melanoma | prion | NF-κB (NF-κB) | Cell Biology | PrP
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 47, pp. 18285 - 18295
OTUB1 is a deubiquitinating enzyme that cleaves Lys-48-linked polyubiquitin chains and also regulates ubiquitin signaling through a unique, noncatalytic... 
UBE2E1 | ubiquitin thioesterase (OTUB1) | deubiquitylation (deubiquitination) | histone | ubiquitin | ubiquitin-conjugating enzyme (E2 enzyme) | MONOUBIQUITINATION | SPECIFICITY | MECHANISM | TRIGGERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BREAST-CANCER | INHIBITION | H2A | UBIQUITYLATION | DEGRADATION | BINDING | Index Medicus | Protein Synthesis and Degradation
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 01/2019, Volume 119, Issue 1, pp. 104 - 116
Abstract Platelet activators stimulate post-translational modification of signalling proteins to change their activity or their molecular interactions leading... 
Cellular Haemostasis and Platelets | deubiquitylation inhibition | GPVI | platelets | sites of ubiquitinylation | SYK | SPECIFICITY | TYROSINE KINASE | C-CBL | PHOSPHATASE | RECEPTOR | RELEASE | UBIQUITINATION | INHIBITION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | AGGREGATION
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 13, pp. 4883 - 4892
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5399 - 5399
Journal Article
by Shang, ZS and Zhao, J and Zhang, Q and Cao, C and Tian, SS and Zhang, K and Liu, L and Shi, L and Yu, N and Yang, SD
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 06/2019, Volume 294, Issue 25, pp. 9844 - 9857
Hyperactivation of the canonical Wnt-signaling pathway is a prominent feature of a number of human malignancies. Transcriptional activation of this signaling... 
MULTIPLE-MYELOMA | PYGOPUS | COMPLEX | LEGLESS | Wnt pathway | ubiquitin-specific peptidase 9 | USP9X | FAT-FACETS | BIOCHEMISTRY & MOLECULAR BIOLOGY | breast cancer | X-linked (USP9X) | BETA-CATENIN | lymphoma 9 (BCL9) | Lys-63-linked polyubiquitins | deubiquitylation (deubiquitination) | carcinogenesis | GENE | cell signaling | B-cell CLL | EXPRESSION | BINDING
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 11/2018, Volume 293, Issue 45, pp. 17362 - 17374
Journal Article