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Immunology, ISSN 0019-2805, 04/2013, Volume 138, Issue 4, pp. 382 - 391
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 04/1996, Volume 183, Issue 4, pp. 1707 - 1718
The CD45 transmembrane glycoprotein has been shown to be a protein phosphotyrosine phosphatase and to be important in signal transduction in T and B... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | PHOSPHORYLATION | TRANSMEMBRANE | KINASE-C | DIFFERENTIATION | IMMUNOLOGY | ANTIGEN RECEPTOR | SIGNAL TRANSDUCTION | EXPRESSION | PROTEIN-TYROSINE-PHOSPHATASE | T-CELLS
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, pp. 12756 - 12756
Thymic selection shapes an appropriate T cell antigen receptor (TCR) repertoire during T cell development. Here, we show that a serine/threonine kinase,... 
SIGNAL | PHOSPHOPROTEOMICS | THRESHOLD | ANTIGEN RECEPTORS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TYROSINE PHOSPHATASES | DEFICIENT MICE | DIFFERENTIATION | T-CELL DEVELOPMENT | EXPRESSION
Journal Article
PLoS Genetics, ISSN 1553-7390, 12/2014, Volume 10, Issue 12, p. e1004768
The molecular determinants that render specific populations of normal cells susceptible to oncogenic reprogramming into self-renewing cancer stem cells are... 
LOOP-HELIX PROTEIN | LYMPHOCYTE DEVELOPMENT | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | GENETICS & HEREDITY | GENOME-WIDE ANALYSIS | C-MYC | TRANSCRIPTIONAL CONTROL | ACUTE MYELOID-LEUKEMIA | T-CELL | TRANSGENIC MICE | Cell Proliferation | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Genetic Loci | LIM Domain Proteins - metabolism | Neoplasm Proteins - metabolism | Cellular Reprogramming | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | T-Cell Acute Lymphocytic Leukemia Protein 1 | Disease Models, Animal | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Promoter Regions, Genetic | Basic Helix-Loop-Helix Transcription Factors - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Receptor, Notch1 - metabolism | Transcription Factors - genetics | Mice, Knockout | Transcription Factors - metabolism | Animals | Cell Transformation, Neoplastic | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | LIM Domain Proteins - genetics | Thymocytes - cytology | Mice | Mutation | Receptor, Notch1 - genetics | Physiological aspects | Transcription factors | Acute lymphocytic leukemia | Health aspects | Hematopoietic stem cells | Medical research | Flow cytometry | Stem cells | Physiology | Gene expression | Cancer
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2017, Volume 47, Issue 7, pp. 1142 - 1152
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2013, Volume 210, Issue 4, pp. 675 - 681
Journal Article
European Journal of Immunology, ISSN 0014-2980, 10/2016, Volume 46, Issue 10, pp. 2363 - 2375
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 08/2019, Volume 216, Issue 8, pp. 1749 - 1761
Preselection thymocytes are normally retained in the thymic cortex, but the mechanisms responsible remain incompletely understood. We now report that deletion... 
SIGNAL | MEDICINE, RESEARCH & EXPERIMENTAL | MEDULLA MIGRATION | LYMPHOCYTE DEVELOPMENT | POSITIVELY SELECTED THYMOCYTES | TRAFFICKING | RECEPTOR | CHEMOKINE | DIFFERENTIATION | IMMUNOLOGY | T-CELL DEVELOPMENT | CUTTING EDGE
Journal Article