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1. Full Text Potent suppression of c-di-GMP synthesis via I-site allosteric inhibition of diguanylate cyclases with 2′-F-c-di-GMP
by Zhou, Jie and Watt, Sarah and Wang, Jingxin and Nakayama, Shizuka and Sayre, David A and Lam, Yiu-fai and Lee, Vincent T and Sintim, Herman O
Bioorganic & medicinal chemistry, ISSN 0968-0896, 07/2013, Volume 21, Issue 14, pp. 4396 - 4404
PDE | DOSY | DGC | PilZ | 2′-F-c-di-GMP | C-di-GMP | G-quadruplex | 2′-H-c-di-GMP | 2′-OMe-c-di-GMP | Polymorphism | 2′-F-c-di-GMP 2′-OMe-c-di-GMP | Allosteric Regulation - drug effects | Magnetic Resonance Spectroscopy | Bacteria - drug effects | Enzyme Inhibitors - pharmacology | Cyclic GMP - analogs & derivatives | Cyclic GMP - metabolism | Cyclic GMP - chemistry | Bacteria - enzymology | Molecular Structure | Escherichia coli Proteins - antagonists & inhibitors | Cyclic GMP - chemical synthesis | Fluorine - chemistry | Phosphorus-Oxygen Lyases - antagonists & inhibitors | Index Medicus
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2. Full Text Sensing the messenger: The diverse ways that bacteria signal through c‐di‐GMP
by Krasteva, Petya Violinova and Giglio, Krista Michelle and Sondermann, Holger
Protein science, ISSN 0961-8368, 07/2012, Volume 21, Issue 7, pp. 929 - 948
protein structure | diguanylate cyclase | signaling | c‐di‐GMP receptors | biofilm formation | phosphodiesterase | c‐di‐GMP | Signaling | c-di-GMP | Diguanylate cyclase | Biofilm formation | c-di-GMP receptors | Protein structure | Phosphodiesterase | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Bacteria - metabolism | Bacteria - chemistry | Phosphoric Diester Hydrolases - metabolism | Signal Transduction | Bacterial Proteins - chemistry | Models, Molecular | Escherichia coli Proteins - metabolism | Phosphoric Diester Hydrolases - chemistry | Cyclic GMP - analogs & derivatives | Cyclic GMP - metabolism | Bacterial Proteins - metabolism | Protein Conformation | Phosphorus-Oxygen Lyases - chemistry | Escherichia coli Proteins - chemistry | Phosphorus-Oxygen Lyases - metabolism | Pharmaceutical industry | Bacteria | Bacterial infections | Index Medicus | Reviews
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3. Full Text A study of Chitosan and c‐di‐GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine
by Svindland, Signe C and Pedersen, Gabriel K and Pathirana, Rishi D and Bredholt, Geir and Nøstbakken, Jane K and Jul‐Larsen, Åsne and Guzmán, Carlos A and Montomoli, Emanuele and Lapini, Giulia and Piccirella, Simona and Jabbal‐Gill, Inderjit and Hinchcliffe, Michael and Cox, Rebecca J
Influenza and other respiratory viruses, ISSN 1750-2640, 11/2013, Volume 7, Issue 6, pp. 1181 - 1193
influenza | H5N1 | vaccine | intranasal | Chitosan | c‐di‐GMP | Th17 | C-di-GMP | Intranasal | Influenza | Vaccine | Infectious Diseases | Life Sciences & Biomedicine | Science & Technology | Virology | Influenza Vaccines - administration & dosage | Adjuvants, Immunologic - administration & dosage | Chitosan - administration & dosage | Cytokines - secretion | Administration, Intranasal | Antibodies, Viral - blood | Cyclic GMP - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Hemagglutination Inhibition Tests | Animal Experimentation | Animals | Influenza Vaccines - immunology | Vaccination - methods | Cyclic GMP - analogs & derivatives | Influenza A Virus, H5N1 Subtype - immunology | Female | Mice | Mice, Inbred BALB C | Influenza vaccines | Avian influenza | Index Medicus | Part 3 | Original
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4. Full Text Biofilms and Cyclic di-GMP (c-di-GMP) signaling: Lessons from Pseudomonas aeruginosa and other bacteria
by Valentini, Martina and Filloux, Alain
The Journal of biological chemistry, ISSN 0021-9258, 06/2016, Volume 291, Issue 24, pp. 12547 - 12555
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Bacteria - metabolism | Humans | Bacterial Proteins - genetics | Biofilms - growth & development | Pseudomonas aeruginosa - physiology | Bacteria - genetics | Biosynthetic Pathways - genetics | Cyclic GMP - analogs & derivatives | Cyclic GMP - metabolism | Pseudomonas aeruginosa - genetics | Models, Biological | Pseudomonas aeruginosa - metabolism | Bacterial Proteins - metabolism | Second Messenger Systems - physiology | Signal Transduction - physiology | Index Medicus | Minireviews | cyclic di-GMP (c-di-GMP) | signaling | antibiotic resistance | Pseudomonas aeruginosa (P. aeruginosa) | biofilm
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5. Full Text Biofilm infections, their resilience to therapy and innovative treatment strategies
by Römling, U and Balsalobre, C
Journal of internal medicine, ISSN 0954-6820, 12/2012, Volume 272, Issue 6, pp. 541 - 561
(p)ppGpp | second messenger | biofilm infections | cAMP | c‐di‐GMP | c‐di‐AMP | Biofilm infections | C-di-GMP | C-di-AMP | Second messenger | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Biofilms - drug effects | Therapies, Investigational - methods | Bacterial Infections - drug therapy | Bacterial Physiological Phenomena - drug effects | Humans | Pseudomonas aeruginosa - physiology | Cyclic GMP - analogs & derivatives | Cyclic GMP - metabolism | Drug Resistance, Bacterial - physiology | Staphylococcus - physiology | Second Messenger Systems - physiology | Anti-Bacterial Agents - pharmacology | Biofilms - classification | Escherichia coli - physiology | Bacterial Infections - microbiology | Anti-infective agents | Health aspects | Staphylococcal infections | Index Medicus | Medicin och hälsovetenskap
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6. Full Text Regulation of flagellar motility during biofilm formation
by Guttenplan, Sarah B and Kearns, Daniel B
FEMS microbiology reviews, ISSN 0168-6445, 11/2013, Volume 37, Issue 6, pp. 849 - 871
brake | motor | EpsE | YcgR | c‐di‐GMP | clutch | Clutch | C-di-GMP | Motor | Brake | Life Sciences & Biomedicine | Microbiology | Science & Technology | Flagella - physiology | Movement | Vibrio - genetics | Bacterial Proteins - genetics | Biofilms - growth & development | Bacterial Physiological Phenomena | Pseudomonas aeruginosa - physiology | Bacillus subtilis - genetics | Bacillus subtilis - physiology | Flagella - metabolism | Pseudomonas aeruginosa - genetics | Escherichia coli - genetics | Bacterial Proteins - metabolism | Vibrio - physiology | Flagella - genetics | Gene Expression Regulation, Bacterial | Escherichia coli - physiology | Index Medicus | c-di-GMP
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