ONCOLOGY (United States), ISSN 0890-9091, 2015, Volume 29, Issue 4, pp. 265 - 275
BRAIN-TUMOR | ONCOLOGY | BEVACIZUMAB | NEWLY-DIAGNOSED GLIOBLASTOMA | LOMUSTINE | VINCRISTINE | RANDOMIZED-TRIAL | PROCARBAZINE | Procarbazine - administration & dosage | Dacarbazine - adverse effects | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Prognosis | Dacarbazine - therapeutic use | Humans | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Neoplasm Grading | Glioma - pathology | Dacarbazine - analogs & derivatives | Vincristine - administration & dosage | Chemotherapy, Adjuvant | Radiotherapy, Adjuvant | Oligodendroglioma - drug therapy | Oligodendroglioma - mortality | Treatment Outcome | Evidence-Based Medicine | Randomized Controlled Trials as Topic | Antineoplastic Agents, Alkylating - therapeutic use | Oligodendroglioma - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Antineoplastic Agents, Alkylating - adverse effects | Neoplasm Staging | Lomustine - administration & dosage | Glioma - drug therapy
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e68333
In high-grade gliomas, the identification of patients that could benefit from EGFR inhibitors remains a challenge, hindering the use of these agents. Using...
PHASE-II TRIAL | KINASE INHIBITION | DIAGNOSED GLIOBLASTOMA-MULTIFORME | MULTIDISCIPLINARY SCIENCES | EPIDERMAL-GROWTH-FACTOR | RECURRENT GLIOBLASTOMA | MALIGNANT GLIOMAS | FACTOR RECEPTOR INHIBITION | BRAIN-STEM GLIOMAS | ONCOGENE ADDICTION | RADIATION-THERAPY | Immunohistochemistry | Immunoassay | Chemoradiotherapy - methods | Humans | Treatment Outcome | Phosphoproteins - metabolism | Xenograft Model Antitumor Assays - methods | Oligodendroglioma - radiotherapy | Receptor, Epidermal Growth Factor - metabolism | Animals | Quinazolines - therapeutic use | Statistics, Nonparametric | Dose Fractionation | Female | Signal Transduction - physiology | Combined Modality Therapy - methods | Mice | Quinazolines - pharmacology | Oligodendroglioma - drug therapy | Ionizing radiation | Radiotherapy | Gefitinib | Gliomas | Phosphoproteins | Analysis | Slopes | Animal models | Brain tumors | Brain cancer | Science | AKT protein | Kinases | Cancer therapies | Experiments | Anticancer properties | Proteins | Angiogenesis | Signal transduction | Pathways | Quality | Xenografts | Epidermal growth factor receptors | Abnormalities | Regrowth | Radiation therapy | Addictions | Signaling | Chemotherapy | Glioma | Medical prognosis | Irradiation | Antitumor activity | Combined treatment | PTEN protein | Tumors | Life Sciences | Cancer
PHASE-II TRIAL | KINASE INHIBITION | DIAGNOSED GLIOBLASTOMA-MULTIFORME | MULTIDISCIPLINARY SCIENCES | EPIDERMAL-GROWTH-FACTOR | RECURRENT GLIOBLASTOMA | MALIGNANT GLIOMAS | FACTOR RECEPTOR INHIBITION | BRAIN-STEM GLIOMAS | ONCOGENE ADDICTION | RADIATION-THERAPY | Immunohistochemistry | Immunoassay | Chemoradiotherapy - methods | Humans | Treatment Outcome | Phosphoproteins - metabolism | Xenograft Model Antitumor Assays - methods | Oligodendroglioma - radiotherapy | Receptor, Epidermal Growth Factor - metabolism | Animals | Quinazolines - therapeutic use | Statistics, Nonparametric | Dose Fractionation | Female | Signal Transduction - physiology | Combined Modality Therapy - methods | Mice | Quinazolines - pharmacology | Oligodendroglioma - drug therapy | Ionizing radiation | Radiotherapy | Gefitinib | Gliomas | Phosphoproteins | Analysis | Slopes | Animal models | Brain tumors | Brain cancer | Science | AKT protein | Kinases | Cancer therapies | Experiments | Anticancer properties | Proteins | Angiogenesis | Signal transduction | Pathways | Quality | Xenografts | Epidermal growth factor receptors | Abnormalities | Regrowth | Radiation therapy | Addictions | Signaling | Chemotherapy | Glioma | Medical prognosis | Irradiation | Antitumor activity | Combined treatment | PTEN protein | Tumors | Life Sciences | Cancer
Journal Article
Critical Reviews in Oncology and Hematology, ISSN 1040-8428, 2007, Volume 66, Issue 3, pp. 262 - 272
Abstract Oligodendrogliomas (OD) are rare, diffusely infiltrating tumors, arising in the white matter of cerebral hemispheres, and displaying better...
Hematology, Oncology and Palliative Medicine | PHASE-III TRIAL | RECURRENT OLIGODENDROGLIOMA | PROGNOSTIC-FACTORS | ONCOLOGY | LOW-GRADE GLIOMA | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | PCV CHEMOTHERAPY | RANDOMIZED-TRIAL | EUROPEAN-ORGANIZATION | COMPARATIVE GENOMIC HYBRIDIZATION | HEMATOLOGY | RADIATION-THERAPY | Prognosis | Brain Neoplasms - diagnosis | Humans | Oligodendroglioma - diagnosis | Brain Neoplasms - pathology | Oligodendroglioma - complications | Brain Neoplasms - complications | Survival | Incidence | Oligodendroglioma - therapy | Oligodendroglioma - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Brain Neoplasms - therapy | Neoplasm Staging | Radiotherapy, Adjuvant
Hematology, Oncology and Palliative Medicine | PHASE-III TRIAL | RECURRENT OLIGODENDROGLIOMA | PROGNOSTIC-FACTORS | ONCOLOGY | LOW-GRADE GLIOMA | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | PCV CHEMOTHERAPY | RANDOMIZED-TRIAL | EUROPEAN-ORGANIZATION | COMPARATIVE GENOMIC HYBRIDIZATION | HEMATOLOGY | RADIATION-THERAPY | Prognosis | Brain Neoplasms - diagnosis | Humans | Oligodendroglioma - diagnosis | Brain Neoplasms - pathology | Oligodendroglioma - complications | Brain Neoplasms - complications | Survival | Incidence | Oligodendroglioma - therapy | Oligodendroglioma - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Brain Neoplasms - therapy | Neoplasm Staging | Radiotherapy, Adjuvant
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 07/2017, Volume 35, Issue 21, pp. 2394 - 2401
The new 2016 WHO brain tumor classification defines different diffuse gliomas primarily according to the presence or absence of IDH mutations (IDH-mt) and...
BRAIN-TUMOR GROUP | PHASE-III TRIAL | MOLECULAR CLASSIFICATION | GROSS-TOTAL RESECTION | ONCOLOGY | LOW-GRADE GLIOMA | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | TERM-FOLLOW-UP | RANDOMIZED-TRIAL | QUALITY-OF-LIFE | EUROPEAN-ORGANIZATION | Astrocytoma - genetics | Prognosis | Astrocytoma - therapy | Oligodendroglioma - genetics | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Combined Modality Therapy | Astrocytoma - pathology | Oligodendroglioma - therapy | Neoplasm Grading | Oligodendroglioma - pathology | Brain Neoplasms - therapy
BRAIN-TUMOR GROUP | PHASE-III TRIAL | MOLECULAR CLASSIFICATION | GROSS-TOTAL RESECTION | ONCOLOGY | LOW-GRADE GLIOMA | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | TERM-FOLLOW-UP | RANDOMIZED-TRIAL | QUALITY-OF-LIFE | EUROPEAN-ORGANIZATION | Astrocytoma - genetics | Prognosis | Astrocytoma - therapy | Oligodendroglioma - genetics | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Combined Modality Therapy | Astrocytoma - pathology | Oligodendroglioma - therapy | Neoplasm Grading | Oligodendroglioma - pathology | Brain Neoplasms - therapy
Journal Article
The Oncologist, ISSN 1083-7159, 02/2009, Volume 14, Issue 2, pp. 155 - 163
Learning Objectives Evaluate the current challenges in the histological diagnosis of oligodendroglial tumors and apply best practices to optimize patient...
19q | Oligoastrocytoma | Temozolomide | MGMT | Oligodendroglioma | EUROPEAN ORGANIZATION | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | PHASE-II | LOW-GRADE OLIGODENDROGLIOMA | VINCRISTINE CHEMOTHERAPY | PCV PROCARBAZINE | RECURRENT OLIGODENDROGLIOMA | ONCOLOGY | INITIAL THERAPY | TEMOZOLOMIDE TREATMENT | COMPARATIVE GENOMIC HYBRIDIZATION | Oligodendroglioma - genetics | Oligodendroglioma - pathology | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Oligodendroglioma - drug therapy | Index Medicus
19q | Oligoastrocytoma | Temozolomide | MGMT | Oligodendroglioma | EUROPEAN ORGANIZATION | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | PHASE-II | LOW-GRADE OLIGODENDROGLIOMA | VINCRISTINE CHEMOTHERAPY | PCV PROCARBAZINE | RECURRENT OLIGODENDROGLIOMA | ONCOLOGY | INITIAL THERAPY | TEMOZOLOMIDE TREATMENT | COMPARATIVE GENOMIC HYBRIDIZATION | Oligodendroglioma - genetics | Oligodendroglioma - pathology | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Oligodendroglioma - drug therapy | Index Medicus
Journal Article
Neurologic Clinics, ISSN 0733-8619, 08/2018, Volume 36, Issue 3, pp. 467 - 484
In the 2016 WHO classification of diffuse glioma, the diagnosis of an (anaplastic) oligodendroglioma requires the presence of both an IDH mutation (mt) and...
PCV | Temozolomide | IDH | 1p/19q codeletion | Anaplastic | Astrocytoma | Bevacizumab | Oligodendroglioma | GROSS-TOTAL RESECTION | PHASE-III | RANDOMIZED-TRIAL | NEUROSCIENCES | CLINICAL NEUROLOGY | BRAIN-TUMOR GROUP | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | TERM-FOLLOW-UP | QUALITY-OF-LIFE | EUROPEAN-ORGANIZATION | SURGICAL RESECTION | 1q/19q codeletion | GLIOMA EORTC 22033-26033
PCV | Temozolomide | IDH | 1p/19q codeletion | Anaplastic | Astrocytoma | Bevacizumab | Oligodendroglioma | GROSS-TOTAL RESECTION | PHASE-III | RANDOMIZED-TRIAL | NEUROSCIENCES | CLINICAL NEUROLOGY | BRAIN-TUMOR GROUP | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | TERM-FOLLOW-UP | QUALITY-OF-LIFE | EUROPEAN-ORGANIZATION | SURGICAL RESECTION | 1q/19q codeletion | GLIOMA EORTC 22033-26033
Journal Article
ONCOLOGY (United States), ISSN 0890-9091, 2013, Volume 27, Issue 4, pp. 326 - 326
Journal Article
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, ISSN 1540-1405, 11/2017, Volume 15, Issue 11, pp. 1331 - 1345
For many years, the diagnosis and classification of gliomas have been based on histology. Although studies including large populations of patients demonstrated...
PHASE-III TRIAL | RANDOMIZED EUROPEAN-ORGANIZATION | MOLECULAR CLASSIFICATION | IDH2 MUTATIONS | ADJUVANT PROCARBAZINE | ONCOLOGY | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | CLINICAL-TRIALS | LOW-GRADE GLIOMAS | DIFFUSE GLIOMAS | 1P/19Q LOSS
PHASE-III TRIAL | RANDOMIZED EUROPEAN-ORGANIZATION | MOLECULAR CLASSIFICATION | IDH2 MUTATIONS | ADJUVANT PROCARBAZINE | ONCOLOGY | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | CLINICAL-TRIALS | LOW-GRADE GLIOMAS | DIFFUSE GLIOMAS | 1P/19Q LOSS
Journal Article
Medicine (United States), ISSN 0025-7974, 03/2016, Volume 95, Issue 9, p. e2583
The purpose of this study was to perform a meta-analysis examining the association of isocitrate dehydrogenase (IDH) 1/2 mutations with overall survival (OS)...
BRAIN-TUMOR GROUP | SURVIVAL | MEDICINE, GENERAL & INTERNAL | GRADE II ASTROCYTOMAS | CODON 132 MUTATION | MGMT | EUROPEAN ORGANIZATION | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | PROCARBAZINE | DIFFUSE GLIOMAS | CHEMOTHERAPY | Prognosis | Humans | Brain Neoplasms - pathology | Proportional Hazards Models | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Glioblastoma - therapy | Disease-Free Survival | Glioblastoma - genetics | Glioblastoma - pathology | Brain Neoplasms - therapy | Biomarkers, Tumor - genetics | Mutation | Research | Gene mutations | Glioblastoma multiforme | Risk factors
BRAIN-TUMOR GROUP | SURVIVAL | MEDICINE, GENERAL & INTERNAL | GRADE II ASTROCYTOMAS | CODON 132 MUTATION | MGMT | EUROPEAN ORGANIZATION | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | PROCARBAZINE | DIFFUSE GLIOMAS | CHEMOTHERAPY | Prognosis | Humans | Brain Neoplasms - pathology | Proportional Hazards Models | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Glioblastoma - therapy | Disease-Free Survival | Glioblastoma - genetics | Glioblastoma - pathology | Brain Neoplasms - therapy | Biomarkers, Tumor - genetics | Mutation | Research | Gene mutations | Glioblastoma multiforme | Risk factors
Journal Article
Cancer Management and Research, ISSN 1179-1322, 05/2017, Volume 9, pp. 159 - 166
Introduction: Oligodendrogliomas (OGs) account for < 20% of all intracranial tumors and 25% of gliomas. Despite improvements in imaging techniques allowing for...
SEER database | Brain cancer | Oligodendroglioma | oligodendroglioma | BEVACIZUMAB | NEWLY-DIAGNOSED GLIOBLASTOMA | RANDOMIZED-TRIAL | brain cancer | CHEMOTHERAPY | RADIATION-THERAPY | TEMOZOLOMIDE | PHASE-III TRIAL | ADJUVANT PROCARBAZINE | ONCOLOGY | ANAPLASTIC OLIGODENDROGLIOMA | RADIOTHERAPY | Development and progression | Care and treatment | Gliomas | Sentinel health events | Methods | Pediatrics | Nuclear magnetic resonance--NMR | Medical imaging | Mortality | Headaches | Clinical trials | Histology | Radiation therapy | Multivariate analysis | Epidemiology | Cancer therapies | Variance analysis | Clinical outcomes | Data bases | Exports | Chemotherapy | Surveillance | Surgery | Population | Standard deviation | Adults | Age | Tumors | SEER Database | Brain Cancer
SEER database | Brain cancer | Oligodendroglioma | oligodendroglioma | BEVACIZUMAB | NEWLY-DIAGNOSED GLIOBLASTOMA | RANDOMIZED-TRIAL | brain cancer | CHEMOTHERAPY | RADIATION-THERAPY | TEMOZOLOMIDE | PHASE-III TRIAL | ADJUVANT PROCARBAZINE | ONCOLOGY | ANAPLASTIC OLIGODENDROGLIOMA | RADIOTHERAPY | Development and progression | Care and treatment | Gliomas | Sentinel health events | Methods | Pediatrics | Nuclear magnetic resonance--NMR | Medical imaging | Mortality | Headaches | Clinical trials | Histology | Radiation therapy | Multivariate analysis | Epidemiology | Cancer therapies | Variance analysis | Clinical outcomes | Data bases | Exports | Chemotherapy | Surveillance | Surgery | Population | Standard deviation | Adults | Age | Tumors | SEER Database | Brain Cancer
Journal Article
Journal of Clinical Neuroscience, ISSN 0967-5868, 2010, Volume 18, Issue 3, pp. 329 - 333
Abstract The increased chemosensitivity of oligodendroglial tumours has been associated with loss of heterozygosity (LOH) of the p arm of chromosome 1 and the...
Neurology | Chemotherapy | Prognosis | Glioma | Chemosensitivity | Survival | Anaplastic oligodendroglioma | Oligodendroglioma | PROGNOSTIC-FACTORS | P53 PROTEIN | OLIGOASTROCYTOMAS | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | TUMORS | NEUROSCIENCES | CLINICAL NEUROLOGY | TEMOZOLOMIDE | PHASE-III TRIAL | GENE | Immunohistochemistry | Oligodendroglioma - mortality | Oligodendroglioma - genetics | Humans | Middle Aged | Brain Neoplasms - pathology | Kaplan-Meier Estimate | Proportional Hazards Models | Tumor Suppressor Protein p53 - metabolism | Brain Neoplasms - genetics | Male | Loss of Heterozygosity | Young Adult | Chromosomes, Human, Pair 19 - genetics | Drug Resistance, Neoplasm - genetics | Oligodendroglioma - pathology | Adult | Female | Aged | Brain Neoplasms - mortality | Chemotherapy, Adjuvant | Chromosomes, Human, Pair 1 - genetics
Neurology | Chemotherapy | Prognosis | Glioma | Chemosensitivity | Survival | Anaplastic oligodendroglioma | Oligodendroglioma | PROGNOSTIC-FACTORS | P53 PROTEIN | OLIGOASTROCYTOMAS | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | TUMORS | NEUROSCIENCES | CLINICAL NEUROLOGY | TEMOZOLOMIDE | PHASE-III TRIAL | GENE | Immunohistochemistry | Oligodendroglioma - mortality | Oligodendroglioma - genetics | Humans | Middle Aged | Brain Neoplasms - pathology | Kaplan-Meier Estimate | Proportional Hazards Models | Tumor Suppressor Protein p53 - metabolism | Brain Neoplasms - genetics | Male | Loss of Heterozygosity | Young Adult | Chromosomes, Human, Pair 19 - genetics | Drug Resistance, Neoplasm - genetics | Oligodendroglioma - pathology | Adult | Female | Aged | Brain Neoplasms - mortality | Chemotherapy, Adjuvant | Chromosomes, Human, Pair 1 - genetics
Journal Article
J Neuropathol Exp Neurol, ISSN 0022-3069, 07/2016, Volume 75, Issue 7, pp. 700 - 710
Spontaneous gliomas in dogs occur at a frequency similar to that in humans and may provide a translational model for therapeutic development and comparative...
Brain tumor | Copy number alteration | Glioma | Dog | Single nucleotide polymorphism (SNP) | Astrocytoma | Cancer genomics | Oligodendroglioma | UNITED-STATES | CLINICALLY RELEVANT SUBTYPES | REPORT PRIMARY BRAIN | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | PROGNOSTIC-FACTOR | SHORT ARM | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | TUMOR-SUPPRESSOR | COMPARATIVE GENOMIC HYBRIDIZATION | COPY-NUMBER ALTERATION | ENDOTHELIAL GROWTH-FACTOR | Species Specificity | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Genetic Association Studies - methods | Male | Signal Transduction - genetics | Glioma - genetics | Animals | Glioma - pathology | Chromosome Aberrations | Dogs | Cell Line, Tumor | Female | Original
Brain tumor | Copy number alteration | Glioma | Dog | Single nucleotide polymorphism (SNP) | Astrocytoma | Cancer genomics | Oligodendroglioma | UNITED-STATES | CLINICALLY RELEVANT SUBTYPES | REPORT PRIMARY BRAIN | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | PROGNOSTIC-FACTOR | SHORT ARM | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMA | TUMOR-SUPPRESSOR | COMPARATIVE GENOMIC HYBRIDIZATION | COPY-NUMBER ALTERATION | ENDOTHELIAL GROWTH-FACTOR | Species Specificity | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Genetic Association Studies - methods | Male | Signal Transduction - genetics | Glioma - genetics | Animals | Glioma - pathology | Chromosome Aberrations | Dogs | Cell Line, Tumor | Female | Original
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 7/2011, Volume 103, Issue 3, pp. 503 - 512
This prospective study was performed to determine the efficacy, safety, and tolerability of concurrent chemoradiotherapy (CCRT) followed by adjuvant...
Neurology | Medicine & Public Health | Concurrent | Oncology | Temozolomide | Chemoradiotherapy | Anaplastic astrocytoma | Anaplastic oligodendroglioma | ADJUVANT CHEMOTHERAPY | ASTROCYTOMA | PROMOTER HYPERMETHYLATION | GLIOBLASTOMA-MULTIFORME | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | VINCRISTINE PCV CHEMOTHERAPY | PHASE-II | CLINICAL NEUROLOGY | MALIGNANT GLIOMA | TRIAL | ONCOLOGY | 1ST RELAPSE | Glioma - mortality | Prospective Studies | Glioma - diagnosis | Dacarbazine - therapeutic use | Brain Neoplasms - diagnosis | Humans | Middle Aged | Kaplan-Meier Estimate | Probability | Male | Combined Modality Therapy | Brain Neoplasms - drug therapy | Glioma - radiotherapy | Antineoplastic Agents, Alkylating - therapeutic use | Young Adult | Time Factors | Adolescent | Dacarbazine - analogs & derivatives | Adult | Female | Retrospective Studies | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Glioma - drug therapy | Care and treatment | Cancer | Index Medicus
Neurology | Medicine & Public Health | Concurrent | Oncology | Temozolomide | Chemoradiotherapy | Anaplastic astrocytoma | Anaplastic oligodendroglioma | ADJUVANT CHEMOTHERAPY | ASTROCYTOMA | PROMOTER HYPERMETHYLATION | GLIOBLASTOMA-MULTIFORME | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | VINCRISTINE PCV CHEMOTHERAPY | PHASE-II | CLINICAL NEUROLOGY | MALIGNANT GLIOMA | TRIAL | ONCOLOGY | 1ST RELAPSE | Glioma - mortality | Prospective Studies | Glioma - diagnosis | Dacarbazine - therapeutic use | Brain Neoplasms - diagnosis | Humans | Middle Aged | Kaplan-Meier Estimate | Probability | Male | Combined Modality Therapy | Brain Neoplasms - drug therapy | Glioma - radiotherapy | Antineoplastic Agents, Alkylating - therapeutic use | Young Adult | Time Factors | Adolescent | Dacarbazine - analogs & derivatives | Adult | Female | Retrospective Studies | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Glioma - drug therapy | Care and treatment | Cancer | Index Medicus
Journal Article
Neuro-Oncology, ISSN 1522-8517, 05/2010, Volume 12, Issue 5, pp. 500 - 507
Glial tumors with oligodendroglial components are considered chemo-responsive. Forty newly diagnosed patients (11 anaplastic oligodendrogliomas [OD] and 29...
19q | Oligodendroglial | Temozolomide | MGMT methylation | temozolomide | HYPERMETHYLATION | PROMOTER METHYLATION | oligodendroglial | OLIGOASTROCYTOMAS | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | CHEMOTHERAPY | CLINICAL NEUROLOGY | 1P/19Q LOSS | GLIOBLASTOMA | ONCOLOGY | MGMT GENE | RADIOTHERAPY | Oligodendroglioma - genetics | Dacarbazine - therapeutic use | Humans | Middle Aged | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Male | Antineoplastic Agents - therapeutic use | Loss of Heterozygosity | Young Adult | Chromosomes, Human, Pair 19 - genetics | DNA Methylation | Gene Deletion | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Adult | Female | Chromosomes, Human, Pair 1 - genetics | Oligodendroglioma - drug therapy | Kaplan-Meier Estimate | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Disease-Free Survival | DNA Modification Methylases - genetics | Oligodendroglioma - pathology | Adolescent | Aged | Index Medicus | Clinical Investigations
19q | Oligodendroglial | Temozolomide | MGMT methylation | temozolomide | HYPERMETHYLATION | PROMOTER METHYLATION | oligodendroglial | OLIGOASTROCYTOMAS | DIAGNOSED ANAPLASTIC OLIGODENDROGLIOMAS | CHEMOTHERAPY | CLINICAL NEUROLOGY | 1P/19Q LOSS | GLIOBLASTOMA | ONCOLOGY | MGMT GENE | RADIOTHERAPY | Oligodendroglioma - genetics | Dacarbazine - therapeutic use | Humans | Middle Aged | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Male | Antineoplastic Agents - therapeutic use | Loss of Heterozygosity | Young Adult | Chromosomes, Human, Pair 19 - genetics | DNA Methylation | Gene Deletion | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Adult | Female | Chromosomes, Human, Pair 1 - genetics | Oligodendroglioma - drug therapy | Kaplan-Meier Estimate | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Disease-Free Survival | DNA Modification Methylases - genetics | Oligodendroglioma - pathology | Adolescent | Aged | Index Medicus | Clinical Investigations
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2014, Volume 50, Issue 14, pp. 2432 - 2448
Abstract Background To determine the net clinical benefit of a new treatment strategy, information on both survival and patient-reported outcomes (PROs) is...
Hematology, Oncology and Palliative Medicine | Patient-reported outcome | Clinical trial | Brain tumour | Clinical decision-making | Quality of life | NEWLY-DIAGNOSED GLIOBLASTOMA | PROGRESSION-FREE SURVIVAL | RECURRENT GLIOBLASTOMA | ADJUVANT TEMOZOLOMIDE | RADIATION-THERAPY | PHASE-III TRIAL | ONCOLOGY | ANAPLASTIC OLIGODENDROGLIOMA | CLINICAL-TRIALS | TERM-FOLLOW-UP | QUALITY-OF-LIFE | Randomized Controlled Trials as Topic - methods | Humans | Middle Aged | Self Report | Brain Neoplasms - therapy | Aged, 80 and over | Quality of Life | Female | Male | Survival Rate | Aged | Patient Outcome Assessment | Brain tumors | Patient outcomes
Hematology, Oncology and Palliative Medicine | Patient-reported outcome | Clinical trial | Brain tumour | Clinical decision-making | Quality of life | NEWLY-DIAGNOSED GLIOBLASTOMA | PROGRESSION-FREE SURVIVAL | RECURRENT GLIOBLASTOMA | ADJUVANT TEMOZOLOMIDE | RADIATION-THERAPY | PHASE-III TRIAL | ONCOLOGY | ANAPLASTIC OLIGODENDROGLIOMA | CLINICAL-TRIALS | TERM-FOLLOW-UP | QUALITY-OF-LIFE | Randomized Controlled Trials as Topic - methods | Humans | Middle Aged | Self Report | Brain Neoplasms - therapy | Aged, 80 and over | Quality of Life | Female | Male | Survival Rate | Aged | Patient Outcome Assessment | Brain tumors | Patient outcomes
Journal Article
Annals of Oncology, ISSN 0923-7534, 09/2012, Volume 23, Issue 10, pp. x33 - x40
Over the last decade, diagnostic options and introduction of novel treatments have expanded the armamentarium in the management of malignant glioma. Combined...
Chemotherapy | MGMT | IDH1 | Anaplastic astrocytoma | Glioblastoma | Oligodendroglioma | oligodendroglioma | CLINICAL-TRIAL | NEWLY-DIAGNOSED GLIOBLASTOMA | RECURRENT GLIOBLASTOMA | chemotherapy | RADIATION-THERAPY | PHASE-II TRIAL | glioblastoma | STEREOTACTIC RADIOSURGERY | ONCOLOGY | CODON 132 MUTATION | anaplastic astrocytoma | ANAPLASTIC OLIGODENDROGLIOMA | MALIGNANT GLIOMAS | HIGH-GRADE GLIOMAS | Meta-Analysis as Topic | Biomarkers, Tumor - analysis | Dacarbazine - therapeutic use | Humans | Brain Neoplasms - pathology | Brain Neoplasms - drug therapy | DNA Repair Enzymes - analysis | Astrocytoma - pathology | Oligodendroglioma - pathology | Glioblastoma - pathology | Astrocytoma - drug therapy | Dacarbazine - analogs & derivatives | Isocitrate Dehydrogenase - metabolism | Aged | Glioblastoma - drug therapy | DNA Modification Methylases - analysis | Oligodendroglioma - drug therapy | Tumor Suppressor Proteins - analysis
Chemotherapy | MGMT | IDH1 | Anaplastic astrocytoma | Glioblastoma | Oligodendroglioma | oligodendroglioma | CLINICAL-TRIAL | NEWLY-DIAGNOSED GLIOBLASTOMA | RECURRENT GLIOBLASTOMA | chemotherapy | RADIATION-THERAPY | PHASE-II TRIAL | glioblastoma | STEREOTACTIC RADIOSURGERY | ONCOLOGY | CODON 132 MUTATION | anaplastic astrocytoma | ANAPLASTIC OLIGODENDROGLIOMA | MALIGNANT GLIOMAS | HIGH-GRADE GLIOMAS | Meta-Analysis as Topic | Biomarkers, Tumor - analysis | Dacarbazine - therapeutic use | Humans | Brain Neoplasms - pathology | Brain Neoplasms - drug therapy | DNA Repair Enzymes - analysis | Astrocytoma - pathology | Oligodendroglioma - pathology | Glioblastoma - pathology | Astrocytoma - drug therapy | Dacarbazine - analogs & derivatives | Isocitrate Dehydrogenase - metabolism | Aged | Glioblastoma - drug therapy | DNA Modification Methylases - analysis | Oligodendroglioma - drug therapy | Tumor Suppressor Proteins - analysis
Journal Article