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1. Full Text Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration
by Cho, Wan-Seob and Kang, Byeong-Cheol and Lee, Jong Kwon and Jeong, Jayoung and Che, Jeong-Hwan and Seok, Seung Hyeok
Particle and Fibre Toxicology, ISSN 1743-8977, 03/2013, Volume 10, Issue 1, pp. 9 - 9
Background: The in vivo kinetics of nanoparticles is an essential to understand the hazard of nanoparticles. Here, the absorption, distribution, and excretion... 
Excretion | ZnO | Absorption | Distribution | Oral administration | TiO2 | GOLD NANOPARTICLES | TRANSLOCATION | CLEARANCE | OXIDATIVE STRESS | ACUTE TOXICITY | DIETARY ZINC | QUANTUM DOTS | PHARMACOKINETICS | TISSUE DISTRIBUTION | MICE | TOXICOLOGY | Zinc Oxide - pharmacokinetics | Drug Administration Schedule | Administration, Oral | Zinc Oxide - toxicity | Body Weight - drug effects | Rats | Titanium - administration & dosage | Body Burden | Male | Rats, Sprague-Dawley | Intestinal Absorption | Zinc Oxide - administration & dosage | Nanoparticles | Tissue Distribution | Titanium - toxicity | Titanium - urine | Zinc Oxide - urine | Animals | Feces - chemistry | Zinc Oxide - blood | Mass Spectrometry | Female | Titanium - pharmacokinetics | Titanium - blood | Zinc oxide | Comparative analysis | Mass spectrometry | Titanium dioxide | Scanning electron microscopy | Biomedical research | Hematology | Fluid | Atoms & subatomic particles | Antimicrobial agents | Nanomaterials | Zinc oxides | Diet | Rodents | Titanium | Life sciences | Feces | Drug dosages | Food
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2. Full Text Effects of Dietary Zinc Oxide Nanoparticles on Growth Performance and Antioxidative Status in Broilers
by Zhao, Cui-Yan and Tan, Shu-Xian and Xiao, Xi-Yu and Qiu, Xian-Shuai and Pan, Jia-Qiang and Tang, Zhao-Xin
Biological Trace Element Research, ISSN 0163-4984, 9/2014, Volume 160, Issue 3, pp. 361 - 367
Broilers in four groups were fed a basal diet supplemented with 60 mg/kg zinc oxide (60-ZnO; control), or 20, 60, or 100 mg/kg ZnO nanoparticles (20-, 60-, and... 
Life Sciences | Biochemistry, general | Nanoparticles | Biotechnology | Nutrition | Oncology | Antioxidative status | ZnO nanoparticles | Broilers | Growth performance | PIGS | OXIDATIVE STRESS | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | COPPER | BIOAVAILABILITY | SUPPLEMENTATION | PIGLETS | LIVER | ENDOCRINOLOGY & METABOLISM | NANOTECHNOLOGY | AGE | Animals | Chickens - growth & development | Liver - enzymology | Time Factors | Antioxidants - metabolism | Zinc Oxide - pharmacology | Dietary Supplements | Superoxide Dismutase - metabolism | Antioxidants | Zinc in the body | Zinc oxide | Superoxide | Growth | Zinc oxides | Physical growth | Poultry | Dietary supplements
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3. Full Text Coated zinc oxide improves intestinal immunity function and regulates microbiota composition in weaned piglets
by Shen, Junhua and Chen, Yan and Wang, Zhisheng and Zhou, Anguo and He, Miao and Mao, Lei and Zou, Huawei and Peng, Quanhui and Xue, Bai and Wang, Lizhi and Zhang, Xiangfei and Wu, Shilin and Lv, Yong
British Journal of Nutrition, ISSN 0007-1145, 06/2014, Volume 111, Issue 12, pp. 2123 - 2134
The present study was conducted to test the hypothesis that low concentrations of coated ZnO, as a substitute for a high concentration of ZnO (2250 mg Zn/kg),... 
Intestinal immunity | Coated zinc oxide | Microbiota composition | Diarrhoea | WEANLING PIGLETS | FED PHARMACOLOGICAL LEVELS | DIETARY SUPPLEMENTATION | ESCHERICHIA-COLI | QUANTITATIVE PCR | GROWTH-PERFORMANCE | NUTRITION & DIETETICS | BACTERIAL COMMUNITIES | GENE-EXPRESSION | INFLAMMATORY RESPONSE | NURSERY PIGS | Zinc Oxide - therapeutic use | Lactobacillus - growth & development | Immunity, Mucosal | Intestinal Mucosa - growth & development | Feces - microbiology | Diarrhea - microbiology | Intestinal Mucosa - immunology | Swine | Zinc Oxide - chemistry | Weight Gain | Jejunum - growth & development | Duodenum - immunology | Microvilli - microbiology | Intestinal Mucosa - ultrastructure | Swine Diseases - metabolism | Diarrhea - veterinary | Microvilli - immunology | Jejunum - immunology | Intestinal Mucosa - microbiology | Duodenum - ultrastructure | Microvilli - metabolism | Microvilli - ultrastructure | Tablets, Enteric-Coated | Sus scrofa | Lactobacillus - isolation & purification | Weaning | Diarrhea - prevention & control | Zinc Oxide - metabolism | Jejunum - ultrastructure | Duodenum - microbiology | Gene Expression Regulation, Developmental | Duodenum - growth & development | Diarrhea - immunology | Escherichia coli - growth & development | Lactobacillus - immunology | Immunologic Factors - chemistry | Immunologic Factors - administration & dosage | Jejunum - microbiology | Escherichia coli - immunology | Immunoglobulin A, Secretory - analysis | Swine Diseases - immunology | Swine Diseases - prevention & control | Energy Intake | Zinc Oxide - administration & dosage | Animals | Escherichia coli - isolation & purification | Swine Diseases - microbiology | Immunologic Factors - metabolism | Crosses, Genetic | Immunologic Factors - therapeutic use | Hogs | Zinc oxides | Immunology | Nutrition | Digestive system
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4. Full Text Lycopene and resveratrol ameliorate zinc oxide nanoparticles-induced oxidative stress in Nile tilapia, Oreochromis niloticus
by Abdel-Daim, Mohamed M and Eissa, Ismail A.M and Abdeen, Ahmed and Abdel-Latif, Hany M.R and Ismail, Mona and Dawood, Mahmoud A.O and Hassan, Ahmed M
Environmental Toxicology and Pharmacology, ISSN 1382-6689, 07/2019, Volume 69, pp. 44 - 50
Industrial products contained nano-zinc oxide (ZnONP) can gain access to the aquaculture environment causing hazardous effects on the living biota. Therefore,... 
Antioxidants | Oxidative stress | Oreochromis niloticus | Lycopene | Zinc oxide nanoparticles | Resveratrol | DIFFERENT ORGANS | TOXICITY | DAMAGE | SUPPLEMENTATION | BIOACCUMULATION | ENVIRONMENTAL SCIENCES | CARP CYPRINUS-CARPIO | ZNO NANOPARTICLES | ANTIOXIDANT STATUS | FISH | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CYTOTOXICITY | Phosphatases | Transmission electron microscopes | Liver | Dietary supplements | Albumin | Superoxide | Nanoparticles | Urea | Fishes | Aquaculture industry | Zinc oxide | Alkaline phosphatase | Drinking water | Toxicity | Biota | Superoxide dismutase | Elevation | Catalase | Animal tissues | Supplementation | Glutathione | Creatinine | Alanine | Kidneys | Ponds | Industrial products | Gills | Tilapia | Exposure | Malondialdehyde | Zinc | Cholesterol | Environmental effects | Serum levels | Hazardous areas | Zinc oxides | Diet | Alanine transaminase | Aspartate aminotransferase | Intoxication | Aquaculture | Index Medicus
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5. Full Text Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens
by Kim, Kyu-Bong and Kim, Young Woo and Lim, Seong Kwang and Roh, Tae Hyun and Bang, Du Yeon and Choi, Seul Min and Lim, Duck Soo and Kim, Yeon Joo and Baek, Seol-Hwa and Kim, Min-Kook and Seo, Hyo-Seon and Kim, Min-Hwa and Kim, Hyung Sik and Lee, Joo Young and Kacew, Sam and Lee, Byung-Mu
Journal of Toxicology and Environmental Health, Part B, ISSN 1093-7404, 04/2017, Volume 20, Issue 3, pp. 155 - 182
Zinc oxide (ZnO), an inorganic compound that appears as a white powder, is used frequently as an ingredient in sunscreens. The aim of this review was to... 
OXIDATIVE STRESS | HUMAN SKIN | PULMONARY INFLAMMATION | OPTICAL-PROPERTIES | ACUTE TOXICITY | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | PHOTOCATALYTIC ACTIVITY | ZNO NANOPARTICLES | TOXICOLOGY | TITANIUM-DIOXIDE | MATERNAL DIETARY ZINC | No-Observed-Adverse-Effect Level | Animals | Cosmetics - toxicity | Risk Assessment | Humans | Zinc Oxide - toxicity | Rats | Models, Animal | Mice | Sunscreening Agents - toxicity | Particle size | Animal models | Toxicity | Anemia | Cream | Pancreatitis | Data processing | Exposure | Powder | Zinc | Inhalation | Cosmetics industry | Nanoparticles | Zinc oxides | Sunscreens | Toxicology | Sunscreen | Risk assessment | Rodents | Zinc oxide | Skin | Topical application
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6. Full Text Effect of dietary zinc oxide on jejunal morphological and immunological characteristics in weaned piglets
by Liu, P and Pieper, R and Tedin, L and Martin, L and Meyer, W and Rieger, J and Plendl, J and Vahjen, W and Zentek, J
Journal of Animal Science, ISSN 0021-8812, 11/2014, Volume 92, Issue 11, pp. 5009 - 5018
The aim of this study was to evaluate age-related changes and the effect of dietary Zn concentration on morphological and immunological characteristics in the... 
Trefoil factor 3 | β-defensin 3 | Zinc oxide | Mucin | Lymphocytes | Morphology | lymphocytes | morphology | trefoil factor 3 | mucin | zinc oxide | PIGS | MUCINS | AGRICULTURE, DAIRY & ANIMAL SCIENCE | beta-defensin 3 | INTESTINAL MORPHOLOGY | LYMPHOCYTE SUBSETS | DELTA T-CELLS | POPULATIONS | COLON | GOBLET CELLS | DEFICIENT | EXPRESSION | Swine - anatomy & histology | Zinc Oxide - pharmacology | Male | Jejunum - immunology | Intestinal Mucosa - drug effects | Jejunum - anatomy & histology | Jejunum - drug effects | Animals | Animal Feed - analysis | Animal Nutritional Physiological Phenomena | Swine - immunology | Female | Dietary Supplements | Diet - veterinary | Swine | Analysis | Gastrointestinal system | Genetic aspects | Genetic transcription | Research | Gene expression
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7. Full Text Zinc oxide nanoparticles provide an adjuvant effect to ovalbumin via a th2 response in Balb/c mice
by Roy, Ruchi and Kumar, Sandeep and Verma, Alok K and Sharma, Akanksha and Chaudhari, Bhushan P and Tripathi, Anurag and Das, Mukul and Dwivedi, Premendra D
International Immunology, ISSN 0953-8178, 2014, Volume 26, Issue 3, pp. 159 - 172
Zinc oxide nanoparticles (ZNPs) have been used in dietary supplements and may cause an immunomodulatory effect. The present study investigated the effect of... 
Allergy | Mast cells | Anaphylaxis | Cytokines | Antigen-presenting cells | GATA3 Transcription Factor - genetics | Adjuvants, Immunologic - administration & dosage | Immunoglobulin G - blood | Ovalbumin - immunology | Humans | Immunoglobulin E - biosynthesis | Th2 Cells - immunology | Immunoglobulin E - blood | Immunoglobulin E - genetics | Immunoglobulin G - biosynthesis | Zinc Oxide - chemistry | Female | Dietary Supplements - adverse effects | Cytokines - genetics | GATA3 Transcription Factor - metabolism | Macrophages - immunology | Cytokines - blood | Metal Nanoparticles - chemistry | Cells, Cultured | Metal Nanoparticles - adverse effects | Suppressor of Cytokine Signaling Proteins - genetics | Up-Regulation - drug effects | Suppressor of Cytokine Signaling 3 Protein | Animals | B-Lymphocytes - immunology | Immunoglobulin G - genetics | Metal Nanoparticles - administration & dosage | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Suppressor of Cytokine Signaling Proteins - metabolism | Cytokines - biosynthesis
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8. Full Text Comparison of porous and nano zinc oxide for replacing high-dose dietary regular zinc oxide in weaning piglets
by Long, Lina and Chen, Jiashun and Zhang, Yonggang and Liang, Xiao and Ni, Hengjia and Zhang, Bin and Yin, Yulong
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0182550
The aim of this study was to compare the effect of dietary supplementation with low dose of porous and nano zinc oxide (ZnO) on weaning piglets, and to... 
PHARMACOLOGICAL CONCENTRATIONS | WEANLING PIGS | ANTIBACTERIAL ACTIVITY | ZNO NANOPARTICLES | IMMUNOLOGICAL CHARACTERISTICS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | WEANED PIGLETS | INFLAMMATORY CYTOKINES | GROWTH-PERFORMANCE | INTESTINAL PERMEABILITY | Weaning | Diarrhea - prevention & control | RNA, Messenger - metabolism | Swine - growth & development | Intestines - immunology | Intestines - anatomy & histology | Kidney - metabolism | Zinc - analysis | Zinc Oxide - chemistry | Malondialdehyde - blood | Muscles - metabolism | Glutathione Peroxidase - metabolism | Intestines - growth & development | Intestines - injuries | Kidney - growth & development | Trefoil Factor-3 - metabolism | Diarrhea - veterinary | Swine Diseases - prevention & control | Zinc Oxide - administration & dosage | Particle Size | Animals | NF-E2-Related Factor 2 - metabolism | Porosity | Kidney Calculi - veterinary | Dietary Supplements | Kidney Calculi - prevention & control | Animal Feed | Nanoparticles | Usage | Dietary supplements | Physiological aspects | Zinc oxide | Genetic aspects | Research | Trefoil factor | Syngeneic grafts | mRNA | Small intestine | Jejunum | Intestine | Rodents | Peroxidase | Supplementation | Injury analysis | Glutathione | Glutathione peroxidase | Kidneys | Nutrition | Duodenum | Diarrhea | Inflammation | Nanostructure | Zinc | Hogs | Zinc oxides | Diet | Feeds
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9. Full Text Growth performance, zinc tissue content, and intestinal health in meat ducks fed different specific surface area of micronized zinc oxide
by Wu, XP and Zhu, YF and Zhang, KY and Ding, XM and Bai, SP and Wang, JP and Peng, HW and Zeng, QF
POULTRY SCIENCE, ISSN 0032-5791, 09/2019, Volume 98, Issue 9, pp. 3894 - 3901
This study investigated the effect of different specific surface area micronized zinc oxide (ZnO) on growth performance, zinc (Zn) tissue content, jejunal... 
IMMUNE-RESPONSE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | MINERALS | intestinal barrier | specific surface area | BACILLUS-COAGULANS | DIETARY ZINC | SUPPLEMENTATION | NANOPARTICLES | micronized zinc oxide | SERUM PARAMETERS | meat duck | zinc tissue content | GENE-EXPRESSION | MORPHOLOGY | NANOSIZE
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10. Full Text Use of coated nano zinc oxide as an additive to improve the zinc excretion and intestinal morphology of growing pigs
by Bai, MMM and Liu, HNN and Xu, K and Wen, CYY and Yu, R and Deng, JPP and Yin, YL
JOURNAL OF ANIMAL SCIENCE, ISSN 0021-8812, 04/2019, Volume 97, Issue 4, pp. 1772 - 1783
Two experiments were designed to explore the effects of coated zinc (Zn) oxide nano-particles (NZO) on the diarrhea ratio, antioxidant capacity, intestinal... 
IMMUNITY | AGRICULTURE, DAIRY & ANIMAL SCIENCE | DIARRHEA | DIETARY SUPPLEMENTATION | growing pigs | MICROBIOTA | TOXICITY | zinc oxide | GROWTH-PERFORMANCE | NANOPARTICLES | intestinal morphology | PIGLETS | SULFATE | GENE-EXPRESSION | zinc excretion
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11. Full Text Effects of zinc oxide-montmorillonite hybrid on growth performance, intestinal structure, and function of broiler chicken
by Hu, C. H and Qian, Z. C and Song, J and Luan, Z. S and Zuo, A. Y
Poultry Science, ISSN 0032-5791, 01/2013, Volume 92, Issue 1, pp. 143 - 150
ABSTRACT A total of 450 one-day-old Arbor Acres male chickens were used to investigate the effects of zinc oxide-montmorillonite hybrid (ZnO-MMT) on growth... 
Broiler chicken | Intestinal microflora | Zinc oxide-montmorillonite hybrid | Intestinal barrier function | Digestive enzyme | AGRICULTURE, DAIRY & ANIMAL SCIENCE | PERMEABILITY | intestinal barrier function | ESCHERICHIA-COLI | CONTROLLED-RELEASE | BARRIER FUNCTION | WEANED PIGS | zinc oxide-montmorillonite hybrid | INTERCALATION | DIETARY ZINC | BIOAVAILABILITY | SUPPLEMENTATION | digestive enzyme | intestinal microflora | broiler chicken | MORPHOLOGY | Intestines - drug effects | Bentonite - pharmacology | Intestines - anatomy & histology | Animals | Chickens - growth & development | Animal Feed - analysis | Zinc Oxide - chemistry | Zinc Oxide - pharmacology | Bentonite - chemistry | Diet - veterinary | Intestines - enzymology | Pancreas - enzymology
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12. Full Text Dietary Zinc Oxide Modulates Antioxidant Capacity, Small Intestine Development, and Jejunal Gene Expression in Weaned Piglets
by Zhu, Cui and Zhu, Cui and Lv, Hang and Lv, Hang and Chen, Zhuang and Chen, Zhuang and Wang, Li and Wang, Li and Wu, Xiuju and Wu, Xiuju and Chen, Zhongjian and Chen, Zhongjian and Zhang, Weina and Zhang, Weina and Liang, Rui and Liang, Rui and Jiang, Zongyong and Jiang, Zongyong
Biological Trace Element Research, ISSN 0163-4984, 2/2017, Volume 175, Issue 2, pp. 331 - 338
The current study was conducted to investigate the effects of dietary zinc oxide (ZnO) on the antioxidant capacity, small intestine development, and jejunal... 
Life Sciences | Biochemistry, general | Biotechnology | Nutrition | Weaned piglets | Tight junction proteins | Intestinal development | Diarrhea | Pro-inflammatory cytokines | Antioxidant capacity | Oncology | Zinc oxide | PHARMACOLOGICAL CONCENTRATIONS | OXIDATIVE STRESS | WEANLING PIGS | PERMEABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BARRIER FUNCTION | GROWTH-PERFORMANCE | SUPPLEMENTATION | CRYPT-VILLUS AXIS | ENDOCRINOLOGY & METABOLISM | NURSERY PIGS | MORPHOLOGY | Gene Expression Regulation - drug effects | Animals | Swine | Antioxidants - metabolism | Zinc Oxide - pharmacology | Dietary Supplements | Jejunum - metabolism | RNA | Genes | Dietary supplements | Zinc in the body | Biological response modifiers | Transforming growth factors | Gene expression | Antioxidants | Analysis | Bone morphogenetic proteins | Interferon | Hogs | Zinc oxides | Weaning | Animal sciences | Index Medicus
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13. Full Text Impact of dietary nano-zinc oxide on immune response and antioxidant defense of broiler chickens
by Hafez, Azza and Nassef, Eldsokey and Fahmy, Mohamed and Elsabagh, Mabrouk and Bakr, Abdelnasser and Hegazi, Elsayed
Environmental Science and Pollution Research, ISSN 0944-1344, 2019, pp. 1 - 7
This study aimed to elucidate the response of broiler chickens to the dietary nano-zinc supplementation in terms of immune response and antioxidant activity.... 
Broiler chickens | Phagocytic activity | Nano-zinc | Immunoglobulin Y | Malondialdehyde | Transformation | Poultry | Antibodies | Superoxide dismutase | Lymphocytes T | Macrophages | Immunity | Blood | Immunity (cell-mediated) | Nanoparticles | Antioxidants | Phagocytes | Enzymatic activity | Catalase | Lymphocytes | Zinc oxide | Lymphocyte transformation | Supplementation | Immune system | Immune response | Dietary supplements | Birds | Superoxide | Zinc | Feeding | Zinc oxides | Monocytes | Diet | Cell number | Chickens | Chicks
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