X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2393) 2393
Publication (129) 129
Newsletter (84) 84
Book Review (21) 21
Book Chapter (14) 14
Magazine Article (9) 9
Dissertation (6) 6
Newspaper Article (5) 5
Data Set (3) 3
Trade Publication Article (3) 3
Conference Proceeding (2) 2
Book / eBook (1) 1
Paper (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1016) 1016
male (923) 923
index medicus (697) 697
vardenafil dihydrochloride (641) 641
animals (578) 578
erectile dysfunction - drug therapy (370) 370
female (364) 364
piperazines - therapeutic use (351) 351
imidazoles - therapeutic use (348) 348
pharmacology & pharmacy (348) 348
middle aged (347) 347
sildenafil citrate (318) 318
rats (317) 317
adult (313) 313
tadalafil (279) 279
sulfones - therapeutic use (274) 274
triazines - therapeutic use (274) 274
erectile dysfunction (272) 272
sapropterin dihydrochloride (272) 272
vardenafil (250) 250
sildenafil (240) 240
phosphodiesterase inhibitors - therapeutic use (237) 237
dihydrochloride (235) 235
treatment outcome (228) 228
urology & nephrology (223) 223
aged (211) 211
piperazines - pharmacology (199) 199
imidazoles - pharmacology (185) 185
analysis (176) 176
biochemistry & molecular biology (174) 174
impotence (171) 171
research (159) 159
piperazines - adverse effects (151) 151
piperazines - administration & dosage (150) 150
dose-response relationship, drug (149) 149
imidazoles - adverse effects (146) 146
efficacy (144) 144
imidazoles - administration & dosage (141) 141
sulfones - pharmacology (141) 141
triazines - pharmacology (141) 141
mice (140) 140
double-blind (133) 133
purines (129) 129
men (124) 124
chemistry, analytical (123) 123
sulfones - administration & dosage (122) 122
triazines - administration & dosage (122) 122
double-blind method (121) 121
carbolines - therapeutic use (120) 120
sulfones (119) 119
triazines (117) 117
sulfones - adverse effects (116) 116
triazines - adverse effects (116) 116
phenylketonuria (112) 112
phosphodiesterase inhibitors - pharmacology (110) 110
care and treatment (108) 108
phosphodiesterase inhibitors - adverse effects (107) 107
time factors (105) 105
nitric oxide (103) 103
trans-1,4-biscyclohexane dihydrochloride - pharmacology (99) 99
in-vitro (97) 97
neurosciences (96) 96
disease models, animal (90) 90
medicine, research & experimental (90) 90
cyclic nucleotide phosphodiesterases, type 5 (87) 87
drug therapy (87) 87
oxidative stress (87) 87
phosphodiesterase inhibitors - administration & dosage (86) 86
therapy (86) 86
safety (83) 83
administration, oral (80) 80
phenylalanine (80) 80
rats, sprague-dawley (80) 80
nitric-oxide (79) 79
penile erection - drug effects (75) 75
phosphodiesterase 5 inhibitors - therapeutic use (75) 75
tetrahydrobiopterin (75) 75
cell biology (73) 73
purines - therapeutic use (73) 73
adolescent (72) 72
health aspects (71) 71
octenidine dihydrochloride (71) 71
drugs (70) 70
phosphodiesterase 5 inhibitors (69) 69
oncology (68) 68
prospective studies (68) 68
endocrinology & metabolism (67) 67
vasodilator agents - therapeutic use (67) 67
chemistry, multidisciplinary (66) 66
rats, wistar (66) 66
cancer (65) 65
physiological aspects (65) 65
expression (63) 63
surveys and questionnaires (63) 63
genetics & heredity (62) 62
methods (61) 61
toxicology (61) 61
phosphodiesterase 5 inhibitors - pharmacology (60) 60
biopterin - analogs & derivatives (59) 59
biophysics (58) 58
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2345) 2345
Chinese (41) 41
German (35) 35
Japanese (31) 31
Russian (23) 23
French (8) 8
Spanish (5) 5
Czech (4) 4
Hungarian (3) 3
Polish (3) 3
Turkish (3) 3
Malay (2) 2
Bulgarian (1) 1
Dutch (1) 1
Norwegian (1) 1
Portuguese (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Food Chemistry, ISSN 0308-8146, 2009, Volume 116, Issue 1, pp. 295 - 301
Journal Article
Molecular Genetics and Metabolism, ISSN 1096-7192, 09/2019
Journal Article
ChemMedChem, ISSN 1860-7179, 04/2017, Volume 12, Issue 7, pp. 487 - 501
Sulfoximines have gained considerable recognition as an important structural motif in drug discovery of late. In particular, the clinical kinase inhibitors for... 
kinase inhibitors | pharmacophores | sulfoximines | drug design | medicinal chemistry | PHOSPHODIESTERASE-5 INHIBITORS | CHEMISTRY, MEDICINAL | ASYMMETRIC-SYNTHESIS | DIELS-ALDER REACTIONS | DEPENDENT KINASE INHIBITOR | BREAST-CANCER | POTENT INHIBITOR | STRUCTURAL BASIS | CDK4/6 INHIBITOR | PHARMACOLOGY & PHARMACY | ERECTILE DYSFUNCTION | Estradiol - analogs & derivatives | Sulfoxides - chemical synthesis | Cyclin-Dependent Kinases - metabolism | Ataxia Telangiectasia Mutated Proteins - metabolism | Imatinib Mesylate - chemical synthesis | Pyrazoles - chemical synthesis | Pyridines - chemistry | Imatinib Mesylate - metabolism | Piperazines - metabolism | Piperazines - chemistry | Aminopyridines - metabolism | Fulvestrant | Aminopyridines - chemistry | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Vardenafil Dihydrochloride - chemistry | Drug Design | Ataxia Telangiectasia Mutated Proteins - antagonists & inhibitors | Cyclin-Dependent Kinases - antagonists & inhibitors | Purines - chemical synthesis | Estradiol - metabolism | Protein Kinase Inhibitors - chemical synthesis | Piperidines - chemistry | Piperidines - metabolism | Purines - metabolism | Pyridines - chemical synthesis | Pyrazoles - metabolism | Piperidines - chemical synthesis | Imatinib Mesylate - chemistry | Vardenafil Dihydrochloride - metabolism | Aminopyridines - chemical synthesis | Sulfoxides - chemistry | Estradiol - chemistry | Purines - chemistry | Pyridines - metabolism | Vardenafil Dihydrochloride - chemical synthesis | Sulfoxides - metabolism | Piperazines - chemical synthesis | Estradiol - chemical synthesis | Protein Kinase Inhibitors - metabolism | Drug discovery | Chemical properties | Pharmaceutical industry | Full Paper | Full Papers
Journal Article
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, ISSN 0937-4477, 05/2014, Volume 271, Issue 5, pp. 887 - 897
We present a meta-analysis of 12 double-blind, randomized, placebo-controlled clinical studies with betahistine in patients suffering from vestibular vertigo... 
Betahistine dihydrochloride | Meniere's disease | PLACEBO | OTORHINOLARYNGOLOGY | DOUBLE-BLIND | BLOOD-FLOW | RECEPTORS | DIHYDROCHLORIDE | Vestibular vertigo | Meta-analysis | MENIERES-DISEASE
Journal Article
Annals of Cardiac Anaesthesia, ISSN 0971-9784, 10/2019, Volume 22, Issue 4, p. 412
Journal Article
Siriraj Medical Journal, 05/2016, Volume 68, Issue 3, pp. 142 - 147
Objective: To evaluate the bioequivalence of 24 mg betahistine dihydrochloride tablets between the test product (Stei® ) and the reference product (Serc® ) in... 
Betahistine dihydrochloride; bioequivalence
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2019, Volume 176, Issue 16, p. 2945
Impaired endothelium-dependent relaxation (EDR) is a hallmark of endothelial dysfunction. A deficiency of tetrahydrobiopterin (BH.sub.4) causes endothelial NOS... 
Unsaturated fatty acids | Genes | Dihydrofolate reductase | Methotrexate | Saturated fatty acids | Sapropterin dihydrochloride | Omega-3 fatty acids | Endothelium
Journal Article
Journal Article
Pediatrics, ISSN 0031-4005, 2013, Volume 131, Issue 6, pp. e1881 - e1888
Journal Article
Toxicology, ISSN 0300-483X, 2011, Volume 289, Issue 2, pp. 141 - 150
Abstract CP-31398 ( N ′-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]- N , N -dimethyl-1,3-propanediamine dihydrochloride) is a styrylquinazoline that... 
Emergency | Chemopreventive agent | Chemotherapeutic agent | N′-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]- N, N-dimethyl-1,3-propanediamine dihydrochloride | CP-31398 | p53 | N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride | P53 | WILD-TYPE | APOPTOSIS | CELLS | dihydrochloride | N '-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine | RESCUE | GENE | GROWTH | MUTANT P53 | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MUTATIONS | Kidney - drug effects | Administration, Oral | Pyrimidines - administration & dosage | Pyrimidines - blood | Metabolome - physiology | Protein Conformation - drug effects | Tumor Suppressor Protein p53 - metabolism | Rats | Male | Excipients - administration & dosage | Dose-Response Relationship, Drug | Kidney - metabolism | Animals | Pyrimidines - toxicity | Excipients - toxicity | Metabolome - drug effects | Protein Stability - drug effects | Dogs | Excipients - metabolism | Female | Phosphatases | Hydroxylation | Oncology, Experimental | Aspartate | Liquid chromatography | Research | Prevention | Urea | Chemotherapy | Metabolites | Physiological aspects | Tumor proteins | Mass spectrometry | Cancer | Lungs | Toxicity | Liver | Biocompatibility | Recovery | Index Medicus | chemopreventive agent | chemotherapeutic agent | N′-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride
Journal Article
Oncotarget, ISSN 1949-2553, 06/2018, Volume 9, Issue 46, pp. 28195 - 28212
Pharmacological treatment of cancer is mostly limited by drug-toxicity and resistance. It has been noticed that new organic ester ligand, diethyl-(... 
O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride | Metastasis | Proliferation | Breast cancer growth | Apoptosis
Journal Article
Molecular genetics and metabolism, ISSN 1096-7192, 08/2019, Volume 128, Issue 1-2, pp. 92 - 101
Phenylketonuria (PKU) is caused by phenylalanine hydroxylase (PAH) deficiency, resulting in high blood and brain Phenylalanine (Phe) concentrations that can... 
Journal Article