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Neurobiology of disease, ISSN 0969-9961, 02/2019, p. 104399
This review describes an adult rat model of status epilepticus (SE) induced by diisopropyl fluorophosphate (DFP), and the beneficial outcomes of transient... 
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 05/2019, Volume 10
Seizures induced by organophosphorus nerve agent exposure become refractory to treatment with benzodiazepines because these drugs engage synaptic... 
diisopropyl fluorophosphate | extrasynaptic | γ-aminobutyric acid-A receptors | nerve agent | midazolam | soman
Journal Article
Epilepsia, ISSN 0013-9580, 07/2019, Volume 60, Issue 7, pp. 1387 - 1398
Exposure to organophosphates (OPs) and OP nerve agents (NAs) causes status epilepticus (SE) and irreversible brain damage. Rapid control of seizure activity is... 
status epilepticus | seizures | diisopropyl fluorophosphate | Fluoro‐Jade B | neuropathology | Fluoro-Jade B | Nerve gas | Anticonvulsants | Neurons | Analysis | Epilepsy | Brain damage | Electroencephalography | Seizures (Medicine) | Neurological diseases | Neuroprotection | EEG | Death | Midazolam | Diisopropyl fluorophosphate | Nerve agents | Brain injury | Benzodiazepines | Seizures | Organophosphates
Journal Article
Environmental Toxicology and Pharmacology, ISSN 1382-6689, 10/2019, Volume 71, p. 103218
A novel panel of oximes were synthesized, which have displayed varying degree of reactivation ability towards different organophosphorus (OP) modified... 
Reactivation | Methyl paraoxon | Aging | Pyridinium oximes | Electric eel AChE | Ethyl paraoxon | Diisopropyl fluorophosphate | Oximes | Incubation | Quaternary | Paraoxon | Pyridinium | Activation | Inhibition | Acetylcholinesterase | Adducts | Organophosphates
Journal Article
Toxicological Sciences, ISSN 1096-6080, 10/2018, Volume 165, Issue 2, pp. 302 - 313
Abstract Many veterans of the 1991 Persian Gulf War (GW) returned with a chronic multisymptom illness that has been termed Gulf War Illness (GWI). Previous GWI... 
Gulf War Illness | mass spectrometry | diisopropyl fluorophosphate | physostigmine | chlorpyrifos | neuroinflammation | CHLORPYRIFOS OXON | TANDEM MASS-SPECTROMETRY | CORTICOSTERONE PRIMES | IMMUNE-SYSTEM | GAS-CHROMATOGRAPHY | CHOLINE LEVELS | INDUCED SICKNESS BEHAVIOR | MICE | TOXICOLOGY | RAT-BRAIN | MULTIPLE NEUROTRANSMITTERS
Journal Article
European Journal of Inorganic Chemistry, ISSN 1434-1948, 05/2014, Volume 2014, Issue 14, pp. 2361 - 2367
Journal Article
Current Organic Chemistry, ISSN 1385-2728, 2019, Volume 23, Issue 5, pp. 628 - 639
Standard therapy of Organophosphorus Compound (OPC) poisoning with oxime-type acetylcholinesterase (AChE) reactivators is unsatisfactory. New bispyridinium... 
rat | cholinesterase | CHOLINESTERASE REACTIVATORS | PYRIDINIUM OXIMES | CHEMISTRY, ORGANIC | ALDOXIME METHYL-CHLORIDE | azinphos-methyl | DFP | BISPYRIDINIUM OXIMES | ACETYLCHOLINESTERASE | nerve agent | pesticides | cox analysis | DIISOPROPYL-FLUOROPHOSPHATE | Acetylcholine | IN-VITRO REACTIVATION | paraoxon | POTENT ANTICHOLINESTERASE | CURRENTLY AVAILABLE OXIMES
Journal Article
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