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Science, ISSN 0036-8075, 04/2018, Volume 360, Issue 6387, pp. 449 - 453
Activated immune cells undergo a metabolic switch to aerobic glycolysis akin to the Warburg effect, thereby presenting a potential therapeutic target in... 
INACTIVATION | ACTIVATION | MULTIPLE-SCLEROSIS | PATHWAY | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | EFFECTOR FUNCTION | SUBSETS | T-CELLS | ACID ESTERS | Myeloid Cells - enzymology | Succinates - chemistry | Autoimmune Diseases - enzymology | Humans | Immunosuppressive Agents - therapeutic use | Mice, Inbred C57BL | Glycolysis - drug effects | Citric Acid Cycle | Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - metabolism | Animals | Lymphocytes - immunology | Dimethyl Fumarate - pharmacology | Dimethyl Fumarate - therapeutic use | Myeloid Cells - immunology | Lymphocytes - drug effects | Lymphocytes - enzymology | Myeloid Cells - drug effects | Cysteine - metabolism | Mice | Immunosuppressive Agents - pharmacology | Autoimmune Diseases - drug therapy | Autoimmunity - drug effects | Biological research | Glyceraldehyde 3-phosphate dehydrogenase | Fumaric acid | Physiological aspects | Glycolysis | Research | Biology, Experimental | Dimethyl | Tricarboxylic acid cycle | Enzymes | Cysteine | Multiple sclerosis | Lymphoid cells | Immune response | Psoriasis | Immunomodulation | Therapeutic applications | Glyceraldehyde | Inflammation | Glyceraldehyde 3-phosphate | Metabolism | Immunity | Krebs cycle | Glyceraldehyde-3-phosphate dehydrogenase | Catalysis | Autoimmune diseases | Immune system
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0120254
Delayed-release dimethyl fumarate (also known as gastro-resistant dimethyl fumarate), an oral therapeutic containing dimethyl fumarate (DMF) as the active... 
CELLS | OXIDATIVE STRESS | MULTIPLE-SCLEROSIS | PATHWAY | MULTIDISCIPLINARY SCIENCES | CHEMOPREVENTIVE AGENT SULFORAPHANE | HEME OXYGENASE-1 | INDUCTION | CYSTEINE RESIDUES | ACID-ESTERS | PHASE-II ENZYMES | Astrocytes - drug effects | Dimethyl Fumarate - chemistry | Glutathione - metabolism | Humans | Fumarates - chemistry | Intracellular Signaling Peptides and Proteins - metabolism | Protein Transport - drug effects | Gene Expression Regulation - drug effects | Extracellular Space - metabolism | Cell Nucleus - metabolism | Dimethyl Fumarate - pharmacology | Fumarates - pharmacology | NF-E2-Related Factor 2 - metabolism | HEK293 Cells | NF-E2-Related Factor 2 - genetics | Cysteine - metabolism | Cell Nucleus - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Astrocytes - metabolism | Cysteine | Thiols | Dimethylformamide | B cells | Psoriasis | Health aspects | Dimethyl | Oxidative stress | Salts | Multiple sclerosis | Transcription | Downstream effects | Activation | Antioxidants | Proteins | Biological effects | Rodents | Modulation | Sensors | Glutathione | Translocation | Mass spectroscopy | Pharmacology | Economic conditions | Nuclear transport | Neurology | Depletion | Acids | Proteomics | Scientific imaging | Conjugation | Mass spectrometry | Cancer
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 03/2012, Volume 15, Issue 3, pp. 361 - 371
Journal Article
Joint Bone Spine, ISSN 1297-319X, 05/2019, Volume 86, Issue 3, pp. 399 - 400
Journal Article
Multiple Sclerosis Journal, ISSN 1352-4585, 5/2019, Volume 25, Issue 6, pp. 876 - 879
Background: Dimethyl fumarate (DMF) is a commonly used and effective treatment for relapsing and remitting multiple sclerosis. Its use results in impairment of... 
Dimethyl fumarate | multiple sclerosis | bone marrow oedema | DENSITY | NEUROSCIENCES | CLINICAL NEUROLOGY | Edema | Multiple sclerosis | Toxicity | Immunomodulation | Gene expression | Bone (trabecular) | Osteoblasts | Tenofovir | Signal transduction | Fractures | Pain | Bone marrow | Bone imaging
Journal Article