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diphosphoinositol pentakisphosphate (61) 61
index medicus (57) 57
humans (47) 47
animals (42) 42
biochemistry & molecular biology (42) 42
inositol phosphates - metabolism (37) 37
phosphotransferases - metabolism (36) 36
pyrophosphates (32) 32
phosphates (31) 31
saccharomyces-cerevisiae (30) 30
inositol (29) 29
metabolism (28) 28
phosphorylation (25) 25
phosphotransferases - genetics (25) 25
hexakisphosphate kinase (23) 23
identification (23) 23
cell biology (22) 22
family (20) 20
polyphosphates (20) 20
inositol phosphates - chemistry (19) 19
inositol pyrophosphate (19) 19
protein (19) 19
kinase (18) 18
signal transduction (18) 18
conserved family (17) 17
inositol hexakisphosphate kinase (17) 17
article (16) 16
enzymes (16) 16
kinases (16) 16
mice (16) 16
phosphotransferases - chemistry (16) 16
amino acid sequence (15) 15
diphosphoinositol polyphosphates (14) 14
molecular sequence data (14) 14
multidisciplinary sciences (14) 14
proteins (14) 14
telomere length (14) 14
cells (13) 13
physiological aspects (13) 13
diphosphoinositol polyphosphate phosphohydrolase (12) 12
hexakisphosphate (12) 12
inositol phosphate (12) 12
purification (12) 12
cell-death (11) 11
homeostasis (11) 11
1,4,5-trisphosphate 3-kinase (10) 10
binding (10) 10
gene deletion (10) 10
inositol phosphates (10) 10
messenger-rna export (10) 10
phosphate (10) 10
saccharomyces cerevisiae - metabolism (10) 10
substrate specificity (10) 10
biochemistry (9) 9
crystal-structure (9) 9
inositol pyrophosphates (9) 9
mutation (9) 9
protein pyrophosphorylation (9) 9
pyrophosphorylation (9) 9
recombinant proteins - metabolism (9) 9
sequence homology, amino acid (9) 9
signaling (9) 9
hyperosmotic stress (8) 8
inositol phosphates - physiology (8) 8
tetrakisphosphate (8) 8
chemistry, multidisciplinary (7) 7
dictyostelium (7) 7
kinetics (7) 7
male (7) 7
models, molecular (7) 7
molecular biology (7) 7
phosphotransferases - antagonists & inhibitors (7) 7
saccharomyces cerevisiae - enzymology (7) 7
signal transduction - physiology (7) 7
yeast (7) 7
biological sciences (6) 6
biology (6) 6
cell line (6) 6
chromatography, high pressure liquid (6) 6
cloning, molecular (6) 6
diphosphates - metabolism (6) 6
growth (6) 6
hexakisphosphate kinase-2 (6) 6
life sciences (6) 6
microbiology (6) 6
myoinositol hexakisphosphate (6) 6
pentakisphosphate (6) 6
phosphatase (6) 6
phospholipase-c (6) 6
phytic acid (6) 6
polyphosphate multikinase (6) 6
polyphosphates - metabolism (6) 6
protein binding (6) 6
rats (6) 6
saccharomyces cerevisiae - genetics (6) 6
sequence alignment (6) 6
acid anhydride hydrolases - metabolism (5) 5
adenosine triphosphate - metabolism (5) 5
binding sites (5) 5
bis-diphosphoinositol tetrakisphosphate (5) 5
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Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2018, Volume 61, Issue 19, pp. 8838 - 8846
Inositol pentakisphosphate 2-kinase catalyzes the phosphorylation of the axial 2-OH of myo-inositol 1,3,4,5,6-pentakisphosphate for de novo synthesis of... 
PHOSPHATE | DIPHOSPHOINOSITOL PENTAKISPHOSPHATE | ACTIVATION | CHEMISTRY, MEDICINAL | SUBSTRATE-BINDING | HEXAKISPHOSPHATE | 1,3,4,5,6-PENTAKISPHOSPHATE 2-KINASE | KINASE | MESSENGER-RNA EXPORT | ARABIDOPSIS | POLYPHOSPHATES
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2015, Volume 466, Issue 1, pp. 105 - 114
Ribosome biogenesis is an essential cellular process regulated by the metabolic state of a cell. We examined whether inositol pyrophosphates, energy-rich... 
Inositol pyrophosphate | Pyrophosphorylation | Diphosphoinositol pentakisphosphate | Kcs1 | Inositol hexakisphosphate kinase | ATP/ADP RATIO | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | inositol hexakisphosphate kinase | POLYPHOSPHATE METABOLISM | KINASE | PROTEIN PYROPHOSPHORYLATION | CELL-GROWTH | YEAST | BIOGENESIS | inositol pyrophosphate | CONSERVED FAMILY | pyrophosphorylation | diphosphoinositol pentakisphosphate | MOLECULAR-BASIS | Transcription, Genetic - drug effects | Saccharomyces cerevisiae - genetics | Phosphotransferases (Phosphate Group Acceptor) - genetics | Ribosomes - metabolism | RNA Polymerase I - metabolism | Saccharomyces cerevisiae - drug effects | Genetic Complementation Test | RNA, Ribosomal - genetics | Protein Subunits - metabolism | Paromomycin - pharmacology | Saccharomyces cerevisiae - metabolism | Hygromycin B - pharmacology | Phosphotransferases (Phosphate Group Acceptor) - metabolism | Protein Synthesis Inhibitors - pharmacology | Inositol Phosphates - metabolism | RNA Polymerase I - genetics | Protein Subunits - genetics | Gene Expression Regulation, Fungal | Signal Transduction | RNA, Ribosomal - metabolism | Inositol Phosphates - pharmacology | Saccharomyces cerevisiae Proteins - genetics | Ribosomes - genetics | Saccharomyces cerevisiae Proteins - metabolism | Protein Biosynthesis - drug effects | ETS, external transcribed spacer | 1PP-IP5 | NTS, non-transcribed spacer | 1,5[PP]2-IP4 | SC, synthetic complete | ITS, internal transcribed spacer | YPD, yeast extract peptone dextrose | NTP, nucleoside triphosphate | UAF, upstream activating factor | IP7, diphosphoinositol pentakisphosphate | CDK, cyclin-dependent kinase | qPCR, quantitative PCR | 5-IP7, 5-diphosphoinositol pentakisphosphate | 6AU, 6-azauracil | DEPC, diethyl pyrocarbonate | IP6, inositol hexakisphosphate | WT, wild type | SC−Met, synthetic complete medium without methionine | 1-IP7, 1-diphosphoinositol pentakisphosphate | Pol I, RNA polymerase I | IP8 bis-diphosphoinositol pentakisphosphate | SC−Ura, synthetic complete medium without uracil | 5PP-IP5
Journal Article
Journal Article
Cellular Signalling, ISSN 0898-6568, 06/2018, Volume 46, pp. 120 - 128
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2013, Volume 452, Issue 3, pp. 369 - 379
Journal Article
Journal of Biosciences, ISSN 0250-5991, 9/2015, Volume 40, Issue 3, pp. 593 - 605
Inositol pyrophosphates are water soluble derivatives of inositol that contain pyrophosphate or diphosphate moieties in addition to monophosphates. The best... 
Microbiology | Zoology | inositol hexakisphosphate (IP 6 ) kinase (IP6K) | diphosphoinositol pentakisphosphate (IP 7 ) | Biomedicine general | Cell Biology | Life Sciences | Bisdiphosphoinositol tetrakisphosphate (IP 8 ) | Life Sciences, general | cell signalling | PP-IP 5 kinase (PPIP5K) | pyrophosphorylation | Plant Sciences | kinase (IP6K) | Bisdiphosphoinositol tetrakisphosphate (IP | PP-IP | inositol hexakisphosphate (IP | kinase (PPIP5K) | diphosphoinositol pentakisphosphate (IP | DIPHOSPHOINOSITOL POLYPHOSPHATES | 1,4,5-TRISPHOSPHATE 3-KINASE | diphosphoinositol pentakisphosphate (IP7) | CRYSTAL-STRUCTURE | PHOSPHOLIPASE-C | ENVIRONMENTAL-STRESS | PROTEIN PYROPHOSPHORYLATION | SACCHAROMYCES-CEREVISIAE | HEXAKISPHOSPHATE KINASE 1 | BIOLOGY | CONSERVED FAMILY | inositol hexakisphosphate (IP6) kinase (IP6K) | PP-IP5 kinase (PPIP5K) | Bisdiphosphoinositol tetrakisphosphate (IP8) | SCHIZOSACCHAROMYCES-POMBE | Inositol Phosphates - chemistry | Animals | DNA Repair - physiology | Eukaryotic Cells - metabolism | Signal Transduction - physiology | Biological Transport - physiology | Apoptosis - physiology | Energy Metabolism - physiology | Inositol Phosphates - metabolism | Inositol | Cellular signal transduction | Genetic engineering | Research | Pyrophosphates | Recombinant proteins | Signal transduction | Eukaryotes | Cellular biology | Molecular biology
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 09/2019, Volume 58, Issue 38, pp. 3927 - 3932
The inositol pyrophosphates (PP-InsPs) are an important group of cellular messengers that influence a broad range of biological processes. To elucidate the... 
DICTYOSTELIUM | DIPHOSPHOINOSITOL PENTAKISPHOSPHATE | HEXAKISPHOSPHATE | PYROPHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | MYOINOSITOL | FAMILY
Journal Article
Cellular Signalling, ISSN 0898-6568, 06/2019, Volume 58, pp. 131 - 136
The inositol pyrophosphate, diphosphoinositol pentakisphosphate (IP7), is thought to negatively regulate the critical insulin signaling protein Akt/PKB.... 
Inositol hexakisphosphate kinase 1 | Diphosphoinositol pentakisphosphate/IP7 | Akt/PKB | Pancreatic beta cell | Insulin signaling | Diphosphoinositol pentakisphosphate/IP | INHIBITION | PATHWAY | DIET-INDUCED OBESITY | INSULIN-FEEDBACK | DELETION | CELL BIOLOGY
Journal Article