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directed alkylating-agents (26) 26
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Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 03/2014, Volume 14, Issue 9, pp. 1271 - 1281
Journal Article
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 06/2007, Volume 7, Issue 6, pp. 627 - 648
Journal Article
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 2001, Volume 8, Issue 5, pp. 533 - 544
Recent work on a number of different classes of anticancer agents that alkylate DNA in the minor groove is reviewed. There has been much work with nitrogen... 
CHEMISTRY, MEDICINAL | DUOCARMYCIN SA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VITRO TRANSCRIPTION | NITROGEN-MUSTARD | ANTITUMOR-ACTIVITY | BENZOIC-ACID MUSTARD | INTERSTRAND CROSS-LINKING | SEQUENCE PREFERENTIAL ALKYLATION | DIRECTED ANILINE MUSTARDS | BIOLOGICAL-ACTIVITY | PHARMACOLOGY & PHARMACY | SECO-CBI-TMI | Anthramycin - metabolism | Distamycins - metabolism | Antibiotics, Antineoplastic - pharmacology | Alkylating Agents - pharmacology | Humans | Cyclohexenes | Benzofurans - pharmacology | Structure-Activity Relationship | Nitrogen Mustard Compounds - chemistry | Netropsin - metabolism | Benzofurans - chemistry | Alkylating Agents - metabolism | Indoles - metabolism | Antibiotics, Antineoplastic - chemistry | Indoles - pharmacology | Cyclohexanecarboxylic Acids - metabolism | Chlorambucil - metabolism | DNA - drug effects | Bisbenzimidazole - metabolism | Chlorambucil - chemistry | Pyrroles - metabolism | Nitrogen Mustard Compounds - pharmacology | Bisbenzimidazole - chemistry | DNA - metabolism | Alkylating Agents - chemistry | Netropsin - analogs & derivatives | Anthramycin - pharmacology | Distamycins - chemistry | DNA - chemistry | Animals | Netropsin - chemistry | Cyclohexanecarboxylic Acids - pharmacology | Nitrogen Mustard Compounds - metabolism | Pyrroles - chemistry | Anthramycin - chemistry | Antibiotics, Antineoplastic - metabolism | Indoles - chemistry | Cyclohexanecarboxylic Acids - chemistry | Benzofurans - metabolism
Journal Article
ANTI-CANCER DRUG DESIGN, ISSN 0266-9536, 06/1999, Volume 14, Issue 3, pp. 187 - 204
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 05/2000, Volume 83, Issue 5, pp. 989 - 994
The cytotoxicities of α‐methylidene‐γ‐butyrolactones, which are linked to coumarins (see 15 and 16) and to potential DNA‐intercalating carriers such as... 
POTENTIAL ANTICANCER AGENTS | ANTITUMOR AGENTS | DIRECTED ALKYLATING-AGENTS | NUCLEIC-ACID BASES | PLATELET-AGGREGATION | CONSEQUENCES | INHIBITORS | URACIL | LINKED ANILINE MUSTARDS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 09/1998, Volume 26, Issue 17, pp. 3933 - 3939
Cisplatin analogues were synthesised that consisted of platinum(ll) diamine complexes tethered via a polymethylene chain (n = 3, 5, 8 and 10) to a... 
CARCINOMA-CELLS | DIRECTED ALKYLATING-AGENTS | SEQUENCE SPECIFICITY | ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGICAL-ACTIVITY | CROSS-LINKING | ANTITUMOR-ACTIVITY | ANILINE MUSTARDS | CIS-DIAMMINEDICHLOROPLATINUM(II) | BINDING
Journal Article
British Journal of Cancer, ISSN 0007-0920, 03/1999, Volume 79, Issue 9-10, pp. 1378 - 1385
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 1996, Volume 6, Issue 8, pp. 933 - 936
In the course of developing novel antitumor agents, we synthesized 3-substituted-1-azaanthraquinones incorporating the alkylating or latent alkylating... 
CONSEQUENCES | CHEMISTRY, ORGANIC | CHEMISTRY, MEDICINAL | DIRECTED ALKYLATING-AGENTS | LINKED ANILINE MUSTARDS
Journal Article
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