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RNA (New York, N.Y.), ISSN 1355-8382, 12/2018, Volume 24, Issue 12, pp. 1677 - 1692
Pre-rRNA processing generates mature 18S, 5.8S, and 28S/25S rRNAs through multistage removal of surrounding 5'-ETS/3'-ETS and intervening ITS1/ITS2 segments.... 
RRP6 | DIS3 | exosome | pre-rRNA processing | XRN2
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2018, Volume 475, Issue 12, pp. 2091 - 2105
DIS3 (defective in sister chromatid joining) is the catalytic subunit of the exosome, a protein complex involved in the 3'-5' degradation of RNAs. DIS3 is a... 
MULTIPLE-MYELOMA | COMPLEX | CYTOPLASMIC MESSENGER-RNA | COLORECTAL-CANCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEGRADATION PATHWAY | CORE EXOSOME | EXORIBONUCLEASE DIS3 | MUTATIONS | RIBOSOMAL-RNA | PIN DOMAIN | RNA stability | PIN domain | myeloma | DIS3 | CMML
Journal Article
Journal Article
by Schormair, Barbara and Zhao, Chen and Bell, Steven and Bell, Robert K and Tilch, Erik and Salminen, Aaro V and Pütz, Benno and Dauvilliers, Yves and Stefani, Ambra and Högl, Birgit and Poewe, Werner and Kemlink, David and Sonka, Karel and Bachmann, Cornelius G and Paulus, Walter and Trenkwalder, Claudia and Oertel, Wolfgang H and Hornyak, Magdolna and Teder-Laving, Maris and Metspalu, Andres and Hadjigeorgiou, Georgios M and Polo, Olli and Fietze, Ingo and Ross, Owen A and Wszolek, Zbigniew and Butterworth, Adam S and Soranzo, Nicole and Ouwehand, Willem H and Roberts, David J and Danesh, John and Allen, Richard P and Earley, Christopher J and Ondo, William G and Xiong, Lan and Montplaisir, Jacques and Gan-Or, Ziv and Perola, Markus and Vodicka, Pavel and Dina, Christian and Franke, Andre and Tittmann, Lukas and Stewart, Alexandre F R and Shah, Svati H and Gieger, Christian and Peters, Annette and Rouleau, Guy A and Berger, Klaus and Oexle, Konrad and Di Angelantonio, Emanuele and Hinds, David A and Müller-Myhsok, Bertram and Winkelmann, Juliane and Balkau, B and Ducimetière, P and Eschwège, E and Rancière, F and Alhenc-Gelas, F and Gallois, Y and Girault, A and Fumeron, F and Marre, M and Roussel, R and Bonnet, F and Bonnefond, A and Cauchi, S and Froguel, P and Cogneau, J and Born, C and Caces, E and Cailleau, M and Lantieri, O and Moreau, JG and Rakotozafy, F and Tichet, J and Vol, S and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Hromatka, Bethann S and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie AM and Pitts, Steven J and Sathirapongsasuti, J Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Collaboration 23andMe Res Team and DESIR Study Grp and DESIR study group and 23andMe Research Team
The Lancet Neurology, ISSN 1474-4422, 11/2017, Volume 16, Issue 11, pp. 898 - 907
Journal Article
Plant Biotechnology, ISSN 1342-4580, 2016
The RNA exosome is a multiprotein complex responsible for 3′ to 5′ degradation and processing of various classes of RNAs in eukaryotes. Rrp44/Dis3 is the... 
Arabidopsis thaliana | RNA exosome | DIS3 | RNA degradation | AtRRP44
Journal Article
Journal Article
Nucleus, ISSN 1949-1034, 01/2019, Volume 10, Issue 1, pp. 21 - 32
The exosome functions to regulate the cellular transcriptome through RNA biogenesis, surveillance, and decay. Mutations in Dis3, a catalytic subunit of the RNA... 
genome instability | SGA | DIS3 | exosome | Saccharomyces cerevisiae | mitotic spindle | RNA | TRANSCRIPTION | EXPORT | MECHANISMS | PIN DOMAIN | CELL BIOLOGY | IMPACT | MUTATIONS | SPECTRUM | SUBUNIT
Journal Article
Cell Reports, ISSN 2211-1247, 03/2019, Volume 26, Issue 10, pp. 2779 - 2791.e5
Cell-based studies of human ribonucleases traditionally rely on methods that deplete proteins slowly. We engineered cells in which the 3′→5′ exoribonucleases... 
EXOSC10/Rrp6 | transcription | non-coding RNA | DIS3 | XRN2 | degradation | exosome | ACCURATE | INITIATION | PROMOTERS | UPSTREAM | HUMAN PM-SCL | POLYMERASE-II | RIBOSOMAL-RNA | MATURATION | EXOSOME COMPLEX | MULTIPLE | CELL BIOLOGY
Journal Article