X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (613) 613
Publication (129) 129
Dissertation (17) 17
Book Chapter (15) 15
Conference Proceeding (3) 3
Book Review (2) 2
Streaming Video (2) 2
Web Resource (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
disc1 (487) 487
schizophrenia (481) 481
index medicus (421) 421
humans (352) 352
neurosciences (309) 309
animals (257) 257
nerve tissue proteins - genetics (253) 253
psychiatry (194) 194
schizophrenia - genetics (194) 194
male (187) 187
mice (170) 170
female (167) 167
bipolar disorder (150) 150
nerve tissue proteins - metabolism (149) 149
brain (143) 143
mental disorders (143) 143
disc1 protein (128) 128
biochemistry & molecular biology (118) 118
genes (108) 108
association (107) 107
article (99) 99
analysis (89) 89
adult (88) 88
disrupted-in-schizophrenia-1 (87) 87
genetic aspects (86) 86
proteins (86) 86
protein (85) 85
translocation (80) 80
neurons (78) 78
disease models, animal (73) 73
genetic predisposition to disease (73) 73
risk (73) 73
mutation (72) 72
expression (71) 71
prefrontal cortex (69) 69
neurite outgrowth (67) 67
risk factors (65) 65
research (60) 60
polymorphism, single nucleotide (59) 59
cell biology (58) 58
gene expression (58) 58
genotype (58) 58
schizophrenia - metabolism (58) 58
genetics (57) 57
genetics & heredity (57) 57
schizophrenia - physiopathology (57) 57
cortex (56) 56
hippocampus (56) 56
middle aged (56) 56
gene (53) 53
brain - metabolism (52) 52
genetic research (52) 52
neurology (52) 52
mice, inbred c57bl (50) 50
case-control studies (48) 48
multidisciplinary sciences (48) 48
protein binding (47) 47
neurogenesis (46) 46
neurons - metabolism (46) 46
neuroscience (45) 45
schizophrenia - pathology (45) 45
mice, transgenic (43) 43
rats (40) 40
autism (39) 39
bipolar disorder - genetics (39) 39
mental illness (39) 39
pharmacology & pharmacy (39) 39
polymorphism, single nucleotide - genetics (39) 39
psychosis (39) 39
rodents (39) 39
genetic predisposition to disease - genetics (38) 38
nudel (37) 37
phenotype (37) 37
animal models (36) 36
physiological aspects (36) 36
signal transduction (36) 36
nervous system (35) 35
depression (34) 34
memory (34) 34
mental disorders - genetics (32) 32
mental-illness (32) 32
schizoaffective disorder (32) 32
genomics (31) 31
gray-matter (31) 31
medical research (31) 31
plasticity (31) 31
medicine (30) 30
neuronal migration (30) 30
binding (29) 29
disrupted-in-schizophrenia-1 disc1 (29) 29
genome-wide association (29) 29
magnetic resonance imaging (29) 29
neurodevelopment (29) 29
progenitor proliferation (29) 29
behavioral phenotypes (28) 28
dopamine (28) 28
hippocampus - metabolism (28) 28
linkage (28) 28
nerve tissue proteins - physiology (28) 28
research article (28) 28
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Biochemical Journal, ISSN 0264-6021, 04/2010, Volume 427, Issue 1, pp. 69 - 78
More than 200 phosphorylated 14-3-3-binding sites in the literature were analysed to define 14-3-3 specificities, identify relevant protein kinases, and give... 
Evolution | 14-3-3 protein | Disrupted-in-schizophrenia 1 (DISC1) | calmodulin-dependent protein kinase | AGC protein kinase | NEURONAL MIGRATION | SIGNALING PATHWAYS | MEMBRANE H+-ATPASE | REGULATING 14-3-3 BINDING | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EUKARYOTIC PROTEIN-KINASES | evolution | NUCLEAR-LOCALIZATION | EXOENZYME-S | STRUCTURAL BASIS | Ca2+/calmodulin-dependent protein kinase | disrupted-in-schizophrenia 1 (DISC1) | ENDOPLASMIC-RETICULUM | Protein Kinases - metabolism | Phosphorylation | Immunoprecipitation | Humans | RNA, Messenger - genetics | Cells, Cultured | Computational Biology | Kidney - cytology | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | 14-3-3 Proteins - metabolism | Nerve Tissue Proteins - metabolism | Kidney - metabolism | Carrier Proteins - metabolism | Protein Binding | Binding Sites | Dimerization | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | 14-3-3 Proteins - genetics | Bcl-2-associated death promoter | AANAT, serotonin acetyltransferase | FOXO, Forkhead box O | KLC, kinesin light chain | CDK5, cyclin-dependent kinase 5 | HEK, human embryonic kidney | MARK, microtubule affinity-regulating kinase | AMPK, AMP-activated protein kinase | EST, expressed sequence tag | PKB, protein kinase B | RSK, ribosomal S6 kinase | CaMK, Ca2 | GLUT4, glucose transporter 4 | protein kinase G | GST, glutathione transferase | HDAC, histone deacetylase | HAP1A, Huntingtin-associated protein 1A | DIG, digoxigenin | PKC, protein kinase C | BAD, Bcl-XL | PP2A, protein phosphatase 2A | DSTT, Division of Signal Transduction Therapy | HA, haemagglutinin | AGC, protein kinase A | Ca2 | PI4K, phosphoinositide 4-kinase | DISC1, disrupted-in-schizophrenia 1 | protein kinase C family kinase | YAP1, yes-associated protein 1
Journal Article
FEBS Letters, ISSN 0014-5793, 08/2012, Volume 586, Issue 17, pp. 2740 - 2750
The molecular architectures of intracellular signaling networks are largely unknown. Understanding their design principles and mechanisms of processing... 
Intrinsic disorder | Macromolecular crowding | Signalosome | Molecular architecture | Signaling network | Signaling complex | SH3 domain | SH2 domain | Sic1 | hepatocyte growth-factor receptor | Frs | CDK | CRKL | growth factor receptor-bound protein 2 | T-cell receptor | GRIP1 | PI3K | signal transducer and activator of transcription 1 | eukaryotic linear motif | NFN hypothesis | glutamate receptor interacting protein 1 | ZBP1 | Dok | sarcoma kinase | CASK | p130Cas | CT-10 related kinase | NR2B | disrupted in schizophrenia 1 | sterile 5 protein | MALS | SLiM | cyclin-dependent kinase | epidermal growth factor | Src-homology 2 domain | Erk | MAPK/Erk kinase | JIP1 | cell division control protein 4 | IGFR | Abl | COP9 | Irs | cAMP | short linear motif | neuronal munc18-1 binding protein 1 | estrogen receptor beta 2 | caudal type homeobox 2 | PTB domain | San1 | N-methyl d-aspartate receptor subtype 2B | insulin receptor substrate | large multi-site docking | ADAP1 | ApoER2 | Cdc4 | NMR | cyclic adenosine monophosphate | constitutive photomorphogenesis protein 9 | N-terminal folding nucleation hypothesis | arf-GAP with dual PH domain-containing protein 1 | Grb2 | Src-homology 3 domain | LAT | breast cancer anti-estrogen resistance 1 | c-Jun-amino-terminal kinase-interacting protein 1 | Mint1 | extracellular signal-regulated kinase | Abelson tyrosine-protein kinase 1 | Crk-associated substrate | PI3 kinase | ELM | SH2 containing protein tyrosine phosphatase 2 | UTR | insulin-like growth factor 1 receptor | Pbs2 | linker for activation of T-cells | Ste5 | ErB2 | calcium/calmodulin-dependent serine protein kinase | apolipoprotein E receptor 2 | PH domain | sterile 11 protein | phosphatidylinositol (3,4,5)-triphosphate | Crk-like protein | Gab | untranslated region | Rack1 | atomic force microscopy | MEK | PIP3 | small angle X-ray scattering | Crk | cryo-electron microscopy | DLK | TCR | Src | AFM | pleckstrin homology domain | phosphotyrosine-binding domain | zip code-binding protein 1 | SHP2 | substrate/subunit/inhibitor of cyclin-dependent protein kinase 1 | receptor of activated protein kinase C 1 | c-Met | DAP-like kinase | DISC1 | cryo-EM | sir antagonist 1 | fibroblast growth factor receptor substrate | LMD | mammalian lin-seven protein | Ste11 | Cdx2 | EGF | STAT1 | docking protein 1 | Rev/Rex activation domain-binding protein | nuclear magnetic resonance | SAXS | Polymyxin B resistance protein 2 | Rab | Grb2-associated-binding protein | insulin receptor | BCAR1 | UNSTRUCTURED PROTEINS | SRC FAMILY KINASE | TYROSINE PHOSPHORYLATION | MAP-KINASE | PROTEIN-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROCESSIVE PHOSPHORYLATION | MESSENGER-RNA LOCALIZATION | CELL BIOLOGY | BIOPHYSICS | COP9 SIGNALOSOME | IN-VIVO | Fungal Proteins - chemistry | Neoplasms - metabolism | Computational Biology - methods | Signal Transduction | Humans | Gene Expression Regulation | Phosphoproteins - metabolism | Protein Interaction Mapping - methods | Insulin - metabolism | Receptor, Epidermal Growth Factor - metabolism | Animals | Models, Biological | Insulin Receptor Substrate Proteins | Receptor, Insulin - metabolism | Tyrosine | Atomic force microscopy | Epidermal growth factor | Phosphatases | Sarcoma | Soups | Fibroblast growth factors | Glutamate | Adenylic acid | T cells | Protein kinases | Protein binding
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2012, Volume 62, Issue 3, pp. 1230 - 1241
In the decade since ( ) was first identified it has become one of the most convincing risk genes for major mental illness. As a multi-functional scaffold... 
Schizophrenia | Neurodevelopment | Association studies | Synapse | DISC1 | Signalling | NEURONAL MIGRATION | ASSOCIATION ANALYSIS | CANDIDATE GENES | AMYLOID PRECURSOR PROTEIN | BIPOLAR DISORDER | NEUROSCIENCES | PERICENTRIN PCNT GENE | PHARMACOLOGY & PHARMACY | MAJOR DEPRESSIVE DISORDER | CENTROSOMAL PROTEINS | TRANSCRIPTION FACTOR | GRAY-MATTER | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Schizophrenia - metabolism | Animals | Carrier Proteins - metabolism | Schizophrenia - genetics | Signal Transduction | Humans | Nerve Tissue Proteins - genetics | Neurogenesis | Enzymes | Synthesis | Glycogen | Genes | Medical genetics | Amyloid beta-protein | Chemical properties | DNA binding proteins | Glutamate | T cells | Protein binding | PI3 K, Phosphatidylinositiol 3-kinase | DISC1, Disrupted in schizophrenia 1 | CRE, cAMP response element | LIS1, Lissencephaly 1 | APP, Amyloid precursor protein | PACAP, Pituitary adenylate cyclase-activating polypeptide | TCF, Lymphoid enhancer factor | T cell factor | CNV, Copy number variation | PDE4, Phosphodiesterase 4 | PCNT, Pericentrin | DBZ, DISC1-binding zinc finger | FEZ1, Fasciculation and elongation protein zeta 1 | BACE1, β-site APP-cleaving enzyme-1 | Rac1, Ras-related C3 botulinum toxin substrate 1 | NDEL1, NDE-like 1 | PCM1, Pericentriolar material 1 | GSK3β, Glycogen synthase kinase 3β | BBS4, Bardet–Biedl syndrome 4 | LEF | Dixdc1, Dishevelled-axin domain containing-1 | NRG, Neuregulin | CEP290, Centrosomal protein 290 kDa | TNIK, Traf2 and Nck interacting kinase | NDE1, Nuclear distribution factor E homologue 1 or Nuclear distribution element 1 | PSD, Post-synaptic density | GluR, Glutamate receptor | mTOR, Mammalian target of rapamycin | ATF4, Activating transcription factor 4 | Kal7, Kalirin-7
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2010, Volume 107, Issue 12, pp. 5622 - 5627
Journal Article
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 5/2013, Volume 70, Issue 9, pp. 1663 - 1672
Journal Article
Neuron, ISSN 0896-6273, 09/2009, Volume 63, Issue 6, pp. 774 - 787
( ), a susceptibility gene for major psychiatric disorders, regulates neuronal migration and differentiation during mammalian brain development. Although roles... 
SYSNEURO | DEVBIO | MOLNEURO | MIGRATION | TRANSPORT | NEUROGENESIS | NEURONAL POLARITY | MECHANISMS | DISC1 | EXPRESSION | NEUROSCIENCES | ADULT | DISRUPTED-IN-SCHIZOPHRENIA-1 | MOTILITY | Membrane Potentials - genetics | Embryo, Mammalian | Vesicular Transport Proteins - metabolism | Humans | Cercopithecus aethiops | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | Cell Movement - genetics | Neurogenesis - genetics | Cell Differentiation - genetics | Dentate Gyrus - embryology | Transfection - methods | Neurons - physiology | Microfilament Proteins - metabolism | Bromodeoxyuridine - metabolism | RNA Interference - physiology | Electric Stimulation - methods | Microfilament Proteins - genetics | Animals, Newborn | Membrane Potentials - drug effects | Growth Cones - physiology | Microfilament Proteins - deficiency | Immunoprecipitation - methods | Mice, Inbred C57BL | Vesicular Transport Proteins - genetics | Cells, Cultured | Rats | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Dentate Gyrus - cytology | Patch-Clamp Techniques | Animals | Vesicular Transport Proteins - deficiency | Analysis of Variance | Neurogenesis - physiology | Dentate Gyrus - growth & development | Protein Binding | Mice | Protein Structure, Tertiary - physiology | Infants (Newborn) | Medical colleges | Neurosciences | Evolutionary biology | RNA | Neurons | Binding proteins | Mental illness | Proteins | Medical research | Brain research | Rodents | Migration | Technological change | Schizophrenia | Kinases | Binding sites
Journal Article