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Search Articles
Journal of leukocyte biology, ISSN 0741-5400, 10/2016, Volume 100, Issue 4, pp. 823 - 833
chemokine receptors | T cell profile | autoimmunity | multivariate discriminant analysis | Autoimmunity | Chemokine receptors | Multivariate discriminant analysis | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | T-Lymphocyte Subsets - immunology | Flow Cytometry - methods | Arthritis, Rheumatoid - blood | Humans | Middle Aged | Male | Gene Expression Profiling | T-Lymphocytes, Helper-Inducer - secretion | Case-Control Studies | T-Lymphocytes, Regulatory - immunology | Antigens, Differentiation, T-Lymphocyte - analysis | Aging - immunology | T-Lymphocytes, Helper-Inducer - immunology | Adult | Female | Cytokines - genetics | T-Lymphocytes, Regulatory - secretion | Cytokines - secretion | Immunophenotyping | Transcription Factors - biosynthesis | Transcription Factors - genetics | Receptors, CXCR3 - analysis | Disease Progression | Lymphocyte Count | Aged | T-Lymphocyte Subsets - secretion | Arthritis, Rheumatoid - immunology | Cytokines - biosynthesis | Index Medicus | cytokine production | disease | peripheral-blood | synovial-fluid | th1 cells | distinct | Klinisk medicin | Clinical Medicine | fibroblasts | collagen-induced arthritis | gamma receptors | chronic inflammation
Journal Article
Microbes and infection, ISSN 1286-4579, 11/2012, Volume 14, Issue 13, pp. 1186 - 1195
Lipids | CD4+ T cells | Mycobacteria | Cytokine | IL-17 | CD4 | T cells | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Miscellaneous | Infectious diseases | Bacterial diseases | Human bacterial diseases | Tuberculosis and atypical mycobacterial infections | Biological and medical sciences | Medical sciences | Bacteriology | T-Lymphocyte Subsets - immunology | Leukocytes, Mononuclear - metabolism | Humans | Antigens, Bacterial - immunology | Interleukin-17 - immunology | CD4-Positive T-Lymphocytes - immunology | Mycobacterium Infections, Nontuberculous - microbiology | Leukocytes, Mononuclear - immunology | Antigens, Surface - isolation & purification | Mycobacterium Infections, Nontuberculous - immunology | Membrane Lipids - immunology | Cytokines - immunology | Cytokines - metabolism | Nontuberculous Mycobacteria - metabolism | CD4-Positive T-Lymphocytes - metabolism | Interleukin-1beta - immunology | Interleukin-23 - immunology | Nontuberculous Mycobacteria - immunology | Interleukin-17 - metabolism | T-Lymphocyte Subsets - metabolism | Interleukin-6 - immunology | Th17 Cells - immunology | Antigens, Surface - immunology | Membrane Lipids - isolation & purification | Cytokines - biosynthesis | Bacteria | Interleukins | Index Medicus | Pathogens | Helper cells | Interleukin 23 | Inflammation | Lymphocytes T | Interleukin 17 | CD4 antigen | Interleukin 6 | Microorganisms | Saprophytes | Peripheral blood mononuclear cells | Differentiation | Cell envelopes | infection | human monocytes | differentiation | Infektionsmedicin | tuberculosis | distinct | Mikrobiologi inom det medicinska området | abscessus | interleukin-17 | Microbiology in the medical area | growth-factor-beta | Infectious Medicine | cytokines | CD4(+) T cells | cystic-fibrosis
Journal Article
Annual review of physiology, ISSN 0066-4278, 03/2009, Volume 72, Issue 1, pp. 413 - 435
Antimicrobial | Innate immunity | Pneumonia | Microbial killing | Respiratory Mucosa - anatomy & histology | Pneumonia - therapy | Infection - therapy | Lung Diseases - diagnosis | Infection - immunology | Lung Diseases - microbiology | Humans | Infection - microbiology | Lung Diseases - therapy | Pneumonia - microbiology | Blood Bactericidal Activity | Lung Diseases - immunology | Respiratory Mucosa - microbiology | Animals | Immunity, Innate - physiology | Infection - diagnosis | Pneumonia - diagnosis | Respiratory Mucosa - immunology | Pneumonia - immunology | Cytokines | Lung diseases | Physiological aspects | Causes of | Anti-infective agents | Research | Leukocytes | Health aspects | Leucocytes | Pathogens | Colon | Lungs | Cells | Index Medicus | Non-typeable Haemophilus influenzae (NTHi): an unencapsulated (hence non-typeable) strain of a Gram-negative bacterial pathogen that is frequently cultured from the lungs of patients with chronic respiratory disease | Interferon (IFN): a subset of cytokines that inhibit viral replication within host cells and activate leukocytes. There are three classes – Type I (α, β, ω, ε, and κ), Type II (γ), and Type III (λ1-3, also known as IL-28A | Interleukin (IL): a widely expressed and highly variable group of cytokine signaling molecules involved in both innate and adaptive immune responses | Innate immunity: host antimicrobial defenses involving detection of conserved molecular motifs by germline-encoded pattern recognition receptors, and characterized by rapid but transient responses of both leukocytes and parenchymal cells | Leucine rich repeats (LRR): common molecular sequences of many pattern recognition receptors that generally occur within pathogen recognition domains | B and IL-29), each with distinct receptors | Transcytosis: mechanism of transport across polarized epithelial cells involving endocytois of extracellular macromolecules or particles on one surface, transcellular vesicle trafficking, and exocytosis on the other surface | Pattern recognition receptors (PRR): membrane-associated, cytosolic or secreted host products that recognize conserved molecular patterns on pathogens, initiating innate immune responses. These include Toll-like receptors (TLR), NOD-like receptors (NLR), RIG-I-like receptors (RLR), class A scavenger receptors (SR-A), and macrophage receptor with collagenous structure (MARCO) | Receptor for advanced glycation end-products (RAGE): a multifunctional member of the immunoglobulin superfamily that recognizes several host immunomodulatory proteins, including HMGB1 and S100, as well as host proteins without immunomodulatory activity that become glycated during aging or inflammation | Resistance: the strategy of host survival of infection that is associated with a reduction in pathogen burden; this is contrasted to tolerance, the strategy of generating a host phenotype indifferent to the pathogen burden | Lipopolysaccharide (LPS): cell wall component of Gram-negative bacteria, the lipid A portion of which is recognized by TLR4 in association with MD2 and CD14 | Complement: a system of more than thirty proteins activated by three pathways that permeabilize pathogens with the membrane attack complex, opsonize microbes and release fragments with signaling properties such as the anaphylotoxins C3a and C5a | Hemolymph: fluid in the body cavity of insects, homologous to vertebrate blood, with most proteins produced by the fat body, homologous to the vertebrate liver, with functions in both metabolism and immunity | Secretory leukocyte proteinase inhibitor (SLPI): epithelium-derived protease inhibitor with intrinsic antibacterial activity | Transmigration: paracellular migration of leukocytes or pathogens through epithelial or endothelial barriers and associated basement membranes | Anoikis: apoptosis of epithelial cells induced by detachment from the extracellular matrix | Toll | Pathogen-associated molecular pattern (PAMP): stereotypic molecular motifs conserved across microbial species that are recognized by pattern recognition receptors, triggering innate immune responses | Damage-associated molecular pattern (DAMP): molecular motifs expressed on or released by infected or injured host cells, also known as danger signals or alarmins | Adaptive immunity: host antimicrobial defenses involving pathogen detection of specific antigens by somatically recombined receptors, and characterized by clonal expansion of pathogen-specific lymphocytes and immunologic memory | Interleukin-1 receptor adaptors (TIR adaptors): host peptides that are selectively recruited to Toll-like receptors and IL-1 receptor upon ligand binding and are required for signal propagation
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2007, Volume 119, Issue 5, pp. 1218 - 1224
Allergy and Immunology | Vogt-Koyanagi-Harada disease | IL-23 | autoimmune disease | IL-17 | proinflammatory cytokine production | interleukin-17 | expression | lymphocytes | autoimmune inflammation | human keratinocytes | distinct | sympathetic ophthalmia | interferon-gamma | rheumatoid-arthritis | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Biological and medical sciences | Medical sciences | Leukocytes, Mononuclear - metabolism | Enzyme-Linked Immunosorbent Assay | Humans | Interleukin-4 - metabolism | CD4-Positive T-Lymphocytes - metabolism | Interleukin-17 - immunology | Uveomeningoencephalitic Syndrome - metabolism | RNA, Messenger - analysis | Male | Interferon-gamma - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-23 - immunology | CD4-Positive T-Lymphocytes - immunology | Interleukin-17 - metabolism | Interleukin-4 - immunology | Uveomeningoencephalitic Syndrome - immunology | Interleukin-23 - metabolism | Interferon-gamma - immunology | Leukocytes, Mononuclear - immunology | Adult | Female | Statistical analysis | Cytokines | Disease | Baldness | Psoriasis | Lymphocytes | Autoimmune diseases | Immune system | Index Medicus | Abridged Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 09/2017, Volume 35, Issue 39, pp. 5235 - 5241
Distinct nasal cytokine profiles | Mouse genetic backgrounds | Intranasal vaccine | Vaccine-induced protection | Colonization | Streptococcus pneumoniae | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Humans | Mice, Inbred C57BL | Antigens, Bacterial - immunology | Pneumococcal Vaccines - therapeutic use | Pneumococcal Vaccines - administration & dosage | Administration, Intranasal | Streptococcus pneumoniae - immunology | Pneumococcal Infections - immunology | Animals | Streptococcus pneumoniae - pathogenicity | Vaccination - methods | Pneumococcal Infections - prevention & control | Mice | Mice, Inbred BALB C | Vaccines | Animal genetics | Antigens | Pneumonia | Analysis | Bacterial pneumonia | Vaccination | Cholera toxin | Water-borne diseases | Mucosa | Immunoglobulin G | Helper cells | Immune clearance | Lymphocytes T | Infections | Streptococcus infections | Proteins | Human populations | Heterogeneity | Reduction | Interleukin 4 | Rodents | Interleukin 1 | Bacteria | Inbreeding | Strains (organisms) | Surface protein A | Public health | Immune system | Immune response | Cytokines | Environmental factors | Protein A | PspA protein | Morbidity | Studies | Interleukin 10 | Cholera | Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 09/2017, Volume 35, Issue 39, p. 5235
Distinct nasal cytokine profiles | Immunology and Microbiology(all) | Mouse genetic backgrounds | Intranasal vaccine | Vaccine-induced protection | veterinary(all) | Infectious Diseases | Molecular Medicine | Public Health, Environmental and Occupational Health | Colonization | Streptococcus pneumoniae
Journal Article
Glia, ISSN 0894-1491, 12/2012, Volume 60, Issue 12, pp. 1930 - 1943
myelin | phenotype | phagocytosis | CELLS | DISTINCT | MHC | IDENTIFICATION | UMCG Approved | heterogeneity | MACROPHAGE ACTIVATION | LPS | MULTIPLE-SCLEROSIS | subpopulation | INFLAMMATION | IN-VIVO | cytokines | TLR | BRAIN | LIPOPOLYSACCHARIDE RECOGNITION | Heterogeneity | Phenotype | Cytokines | Myelin | Subpopulation | Phagocytosis | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Animals, Newborn | Microglia - metabolism | Humans | Mice, Inbred C57BL | Cells, Cultured | Male | Mice, Transgenic | Toll-Like Receptor 4 - metabolism | Brain - metabolism | Toll-Like Receptor 4 - physiology | Animals | Microglia - classification | Brain - pathology | Microglia - pathology | Aged | Mice | Physiological aspects | Antigens | Skin diseases | Skin | Index Medicus | Medicin och hälsovetenskap
Journal Article
Scandinavian journal of immunology, ISSN 0300-9475, 09/2019, Volume 90, Issue 3, pp. e12794 - n/a
experimental animals | cytokines | transcription factors | natural killer T cells | Life Sciences & Biomedicine | Immunology | Science & Technology | T-Lymphocyte Subsets - immunology | Antigens, CD1d - immunology | NK Cell Lectin-Like Receptor Subfamily K - immunology | Galactosylceramides - metabolism | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Interferon-gamma - metabolism | Promyelocytic Leukemia Zinc Finger Protein - immunology | Lymphocyte Activation - immunology | Promyelocytic Leukemia Zinc Finger Protein - metabolism | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Natural Killer T-Cells - metabolism | Killer Cells, Natural - immunology | Female | Biomarkers - metabolism | Mice, Inbred C57BL | Antigens, CD1d - metabolism | Animals | Galactosylceramides - immunology | T-Lymphocyte Subsets - metabolism | Interferon-gamma - immunology | Mice | Killer Cells, Natural - metabolism | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Natural Killer T-Cells - immunology | Killer cells | T cells | Leukemia | Cells | Populations | CD8 antigen | Lymphocytes T | T-cell receptor | CD69 antigen | Receptors | Lymphocytes | Zinc finger proteins | Natural killer cells | CD122 antigen | Phenotypes | Markers | CD62L protein | Exploration | T cell receptors | CXCR3 protein | Zinc | CD4 antigen | CD1d antigen | Major histocompatibility complex | Reagents | Ligands | Interferon | Galactosylceramide | CD45RB antigen | Index Medicus | Experimental Immunology | expression | distinct | Immunologi inom det medicinska området | mice | population | receptor | identification | repertoire | plzf | Immunology in the medical area | nkt cells | prevention
Journal Article
The EMBO journal, ISSN 0261-4189, 12/2002, Volume 21, Issue 23, pp. 6409 - 6418
CYTOKINES | DOMAIN | oncostatin M | PROTEIN | EXOCYTOSIS | DISTINCT | GP130 | HepG2 cell | PLASMA-MEMBRANE | UMCG Approved | INTERLEUKIN-6 FAMILY | apical plasma membrane | sphingomyelin | subapical compartment | POLARIZED SPHINGOLIPID TRANSPORT | Sphingomyelin | Apical plasma membrane | Subapical compartment | Oncostatin M | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cyclic AMP-Dependent Protein Kinases - metabolism | Bile Canaliculi - growth & development | Cytokine Receptor gp130 | Epithelium - growth & development | Epithelium - metabolism | Membrane Glycoproteins - metabolism | Humans | Cells, Cultured | Antigens, CD - metabolism | Peptides - pharmacology | Peptides - metabolism | Bile Canaliculi - metabolism | Cell Membrane - metabolism | Index Medicus
Journal Article
Clinical and experimental allergy, ISSN 0954-7894, 12/2007, Volume 37, Issue 12, pp. 1798 - 1808
inflammation | IL-17 | remodelling | active smoking | allergy | asthma | chronic | Th17 | emphysema | RISK-FACTORS | DISTINCT | ADULTS | UMCG Approved | CIGARETTE-SMOKING | SENSITIZATION | LINEAGE | T-CELLS | IL‐17 | Active smoking | Allergy | Remodelling | Chronic | Inflammation | Emphysema | Asthma | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Biological and medical sciences | Allergic diseases | Medical sciences | Neutrophils - cytology | Cell Proliferation | Mice, Inbred C57BL | Pneumonia - pathology | Male | Macrophages - cytology | Smoke | Ovalbumin - pharmacology |