X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
dll3 (68) 68
humans (37) 37
index medicus (27) 27
spondylocostal dysostosis (25) 25
animals (24) 24
genetics & heredity (24) 24
mutation (21) 21
female (20) 20
membrane proteins - genetics (20) 20
mice (20) 20
male (16) 16
notch (15) 15
segmentation (15) 15
mutations (14) 14
spine - abnormalities (14) 14
delta-homolog (13) 13
gene (13) 13
membrane proteins - metabolism (13) 13
signal transduction (13) 13
intracellular signaling peptides and proteins (12) 12
developmental biology (11) 11
ligands (11) 11
phenotype (11) 11
defects (10) 10
radiography (10) 10
research (10) 10
congenital scoliosis (9) 9
expression (9) 9
gene expression (9) 9
gene expression regulation, developmental (9) 9
intracellular signaling peptides and proteins - genetics (9) 9
oncology (9) 9
pedigree (9) 9
scoliosis - genetics (9) 9
somitogenesis (9) 9
abnormalities, multiple - genetics (8) 8
adolescent (8) 8
axial skeletal defects (8) 8
cancer (8) 8
child (8) 8
genetic aspects (8) 8
in situ hybridization (8) 8
intracellular signaling peptides and proteins - metabolism (8) 8
ribs - abnormalities (8) 8
spine - diagnostic imaging (8) 8
article (7) 7
cell biology (7) 7
dysostoses - genetics (7) 7
lung cancer (7) 7
notch signaling pathway (7) 7
receptors, notch - metabolism (7) 7
small cell lung cancer (7) 7
syndrome (7) 7
anomalies (6) 6
causes spondylocostal dysostosis (6) 6
chemotherapy (6) 6
child, preschool (6) 6
infant (6) 6
mice, mutant strains (6) 6
notch pathway (6) 6
receptors, notch (6) 6
rovalpituzumab tesirine (6) 6
scoliosis (6) 6
somite (6) 6
tbx6 (6) 6
tumors (6) 6
abnormal vertebral segmentation (5) 5
adult (5) 5
alagille-syndrome (5) 5
apoptosis (5) 5
basic helix-loop-helix transcription factors - genetics (5) 5
delta-like 3 (5) 5
drosophila (5) 5
dysostoses - diagnostic imaging (5) 5
dysostosis (5) 5
jarcho-levin-syndrome (5) 5
lfng (5) 5
lung cancer, small cell (5) 5
mouse embryo (5) 5
notch protein (5) 5
pathway (5) 5
pattern (5) 5
receptor, notch1 - metabolism (5) 5
abnormalities, multiple - pathology (4) 4
anatomy & morphology (4) 4
care and treatment (4) 4
clinical trials (4) 4
diagnosis (4) 4
dna mutational analysis (4) 4
dysostoses - embryology (4) 4
dysplasia (4) 4
form (4) 4
genes (4) 4
infant, newborn (4) 4
lunatic-fringe (4) 4
mesp2 (4) 4
mice, knockout (4) 4
mouse (4) 4
multidisciplinary sciences (4) 4
notch ligands (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Lung Cancer, ISSN 0169-5002, 09/2019, Volume 135, pp. 33 - 39
The aim of the study was to characterize and evaluate the presence of DLL3-positive Circulating Tumor Cells (CTCs) in SCLC patients receiving front-line... 
Vimentin | SCLC | CTCs | DLL3 | SURVIVAL | STEM-CELLS | ONCOLOGY | PATHWAY | RESPIRATORY SYSTEM | NEUROENDOCRINE | EXPRESSION | PROGRESSION
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2015, Volume 7, Issue 302, pp. 302ra136 - 302ra136
Journal Article
Cancer research, ISSN 0008-5472, 7/2017, Volume 77, Issue 14, pp. 3931 - 3941
The Notch ligand DLL3 has emerged as a novel therapeutic target expressed in small cell lung cancer (SCLC) and high-grade neuroendocrine carcinomas.... 
Small cell lung cancer | immunoPET | Delta-like protein 3 | DLL3
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2019, Volume 514, Issue 3, pp. 853 - 860
Delta-like protein 3 (DLL3) has been reported as a biomarker in various human tumors. However, the biological function and mechanism of it in advanced small... 
SCLC | LIN28B | miR-518d-5p | EMT | DLL3 | Immunohistochemistry | Medical colleges | Chemotherapy | RNA | Analysis | Oncology, Experimental | Lung cancer, Small cell | Research | Protein binding | Cancer
Journal Article
Lung Cancer, ISSN 0169-5002, 09/2019, Volume 135, pp. 73 - 79
Delta-like protein 3 (DLL3), an inhibitory Notch ligand, is the target for rovalpituzumab tesirine in development for the treatment of small cell lung cancer... 
Small cell lung cancer | Carcinoid tumors | Rovalpituzumab tesirine | DLL3 | ONCOLOGY | RESPIRATORY SYSTEM | CANCER | Medicine, Experimental | Medical research | Lung cancer | Tumors
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2008, Volume 105, Issue 32, pp. 11212 - 11217
Genetic studies have shown that ubiquitination and endocytosis of the Drosophila ligand Delta in signal-sending cells are required for activation of Notch... 
DELTA1 | transendocytosis | MULTIDISCIPLINARY SCIENCES | recycling | ENDOCYTOSIS | CELL FATE | DROSOPHILA | ACTIVATE NOTCH | DLL3 | membrane microdomains | ubiquitination | PATHWAY | DSL LIGANDS | EPSIN
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 4842 - 11
Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis. We previously showed that expression of Delta-like 3 (DLL3), a member of the... 
CELLS | HDACS | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | PATTERNS | HUMAN HEPATOCELLULAR-CARCINOMA | CANCER | DLL3 | Histone deacetylase | Chromatin | Hepatocellular carcinoma | Infections | Genomes | siRNA | Hepatitis | DNA methylation | Notch protein | Acetylation | X protein | Viral infections | Hepatitis B | Apoptosis
Journal Article
Molecular & Cellular Oncology, ISSN 2372-3556, 03/2016, Volume 3, Issue 2, p. e1101515
Delta-like protein 3 (DLL3) is a novel and tractable tumor-initiating cell-associated target for the antibody-drug conjugate SC16LD6.5 in high-grade pulmonary... 
SCLC | Tumor-initiating cell | Notch | DLL3 | TIC
Journal Article
Cancer Science, ISSN 1347-9032, 10/2019, Volume 110, Issue 10, pp. 3122 - 3131
Delta‐like 3 (DLL3) is a member of the Delta/Serrate/Lag2 (DSL) group of Notch receptor ligands. Five DSL ligands are known in mammals, among which DLL3 has a... 
neuroendocrine carcinoma | apoptosis | chromogranin A | neuroendocrine | DLL3 | Cancer | Lung cancer | Granule cells | Gastrointestinal tract | Malignancy | Lung carcinoma | Metastasis | Tumor cell lines | Electron microscopy | Medical schools | Western blotting | Proteins | Gene silencing | Cell lines | DNA methylation | Epigenetics | Ligands | Notch protein | Gastric cancer | Apoptosis
Journal Article
Expert review of anticancer therapy, ISSN 1473-7140, 06/2019, Volume 19, Issue 6, pp. 461 - 471
: Small-cell lung cancer (SCLC) is a highly aggressive neuroendocrine tumour, and its outcome is strongly conditioned by the rapid onset of resistance to... 
targeted therapy | Notch pathway | PROTEIN | PARP inhibitors | rovalpituzumab tesirine | CISPLATIN RESISTANCE | DRUG-RESISTANCE | DLL3 | PHASE-III TRIAL | chemoresistance | ETOPOSIDE | ONCOLOGY | Small-cell lung cancer (SCLC) | IN-VIVO | LINE | IRINOTECAN | MULTIDRUG-RESISTANCE | EXPRESSION
Journal Article
Journal Article
Cellular Oncology, ISSN 2211-3428, 6/2019, Volume 42, Issue 3, pp. 261 - 273
Small-cell lung cancer (SCLC) is an aggressive disease with still limited therapeutic options. Despite being both a chemo- and radiation-sensitive malignancy,... 
Biomedicine, general | Pathology | Notch pathway | Biomedicine | Rovalpituzumab tesirine | Cancer Research | Oncology | Small cell lung cancer (SCLC) | DLL3
Journal Article
Journal Article
Human Mutation, ISSN 1059-7794, 03/2017, Volume 38, Issue 3, pp. 317 - 323
Journal Article