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Cancer Research, ISSN 0008-5472, 08/2017, Volume 77, Issue 15, pp. 4102 - 4115
IDH1-mutant gliomas are dependent upon the canonical coenzyme NAD(+) for survival. It is known that PARP activation consumes NAD(+) during base excision repair... 
GLIOMA-CELLS | IDH2 MUTATIONS | GLIOBLASTOMA | REPAIR | INHIBITION | ONCOLOGY | GENOMIC ANALYSIS | PHENOTYPE | RESISTANCE | MSH6 MUTATIONS | DEHYDROGENASE | Humans | Enzyme Inhibitors - pharmacology | Antineoplastic Agents, Alkylating - pharmacology | Isocitrate Dehydrogenase - genetics | Random Allocation | Mice, SCID | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Glioma - metabolism | Glioma - genetics | NAD | Xenograft Model Antitumor Assays | Animals | Piperidines - pharmacology | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Cell Line, Tumor | Female | Mice | Stress, Physiological - drug effects | Mutation | Acrylamides - pharmacology | NADPH | Toxicity | DNA damage | Genotoxicity | Methyltransferase | Cytotoxicity | Biosynthesis | Activation | DNA repair | Cancer therapies | Base excision repair | Alkylation | Anticancer properties | Pathways | Metabolites | Mismatch repair | Xenografts | Biocompatibility | Phosphoribosyltransferase | Repair | Damage | Deoxyribonucleic acid--DNA | Methylguanine | Poly(ADP-ribose) polymerase | Durability | Metabolism | Chemotherapy | Depletion | Inhibitors | Nicotinamide phosphoribosyltransferase | Cell lines | Metabolic pathways | Nicotinamide | Temozolomide | Cancer | Index Medicus | IDH1 mutation | PARP | NAMPT inhibitor | Glioblastoma
Journal Article
Journal Article
Journal of Pineal Research, ISSN 0742-3098, 04/2013, Volume 54, Issue 3, pp. 303 - 312
UV radiation (UVR) induces serious structural and functional alterations in human skin leading to skin aging and carcinogenesis. Reactive oxygen species are... 
8‐hydroxy‐2'‐deoxyguanosine | ultraviolet radiation | superoxide dismutase | human full‐thickness skin | melatonin | catalase | glutathione peroxidase | human full-thickness skin | 8-hydroxy-2'-deoxyguanosine | OXIDATIVE STRESS | PHYSIOLOGY | MECHANISM | INDUCED APOPTOSIS | GLUTATHIONE-PEROXIDASE | KERATINOCYTES | NEUROSCIENCES | OXYGEN | IN-VITRO | ENDOCRINOLOGY & METABOLISM | SYSTEMS | ULTRAVIOLET-RADIATION | HUMAN EPIDERMIS | 8-hydroxy-2 '-deoxyguanosine | Immunohistochemistry | Superoxide Dismutase - genetics | Skin Physiological Phenomena - drug effects | Superoxide Dismutase - biosynthesis | Skin - metabolism | Antioxidants - metabolism | Humans | Middle Aged | Young Adult | Ultraviolet Rays | Adult | Real-Time Polymerase Chain Reaction | Deoxyguanosine - analogs & derivatives | Organ Culture Techniques | Superoxide Dismutase - metabolism | Glutathione Peroxidase - metabolism | Catalase - genetics | Antioxidants - pharmacology | Glutathione Peroxidase - biosynthesis | Skin - enzymology | Glutathione Peroxidase - genetics | Catalase - metabolism | Analysis of Variance | Skin - radiation effects | Deoxyguanosine - metabolism | DNA Damage | Catalase - biosynthesis | Melatonin - pharmacology | Skin - drug effects | Enzymes | Melatonin | Nuclear radiation | DNA damage | Genes | DNA | Genetic research | Superoxide | Skin | Gene expression | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2007, Volume 204, Issue 1, pp. 57 - 63
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 05/2012, Volume 209, Issue 5, pp. 1001 - 1010
Journal Article
Nature Neuroscience, ISSN 1097-6256, 04/2011, Volume 14, Issue 4, pp. 459 - 468
Journal Article
Journal Article