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PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 4, p. e62087
Silica nanoparticles have become promising carriers for drug delivery or gene therapy... 
PATHWAYS | MAINTENANCE | AIR-POLLUTION | OXIDATIVE STRESS | CHK1 | PARTICLES | MULTIDISCIPLINARY SCIENCES | DISEASE | MITOCHONDRIA | SIZE-DEPENDENT CYTOTOXICITY | CANCER | Protein Kinases - metabolism | Reactive Oxygen Species - metabolism | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Membrane Potential, Mitochondrial - drug effects | Necrosis | Flow Cytometry | G2 Phase Cell Cycle Checkpoints - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | Intracellular Space - drug effects | Subcellular Fractions - drug effects | Endocytosis - drug effects | Nanoparticles - ultrastructure | Hydrodynamics | Static Electricity | Comet Assay | Nanoparticles - toxicity | Subcellular Fractions - metabolism | Particle Size | Human Umbilical Vein Endothelial Cells - enzymology | Silicon Dioxide - toxicity | Intracellular Space - metabolism | Checkpoint Kinase 1 | Human Umbilical Vein Endothelial Cells - pathology | DNA Damage | Oxidative Stress - drug effects | Drugs | Nanoparticles | Drug delivery systems | DNA | DNA damage | Superoxide | Radiation, Background | DNA repair | Silica | Vehicles | Endothelium | Cdc2 protein | Reactive oxygen species | Intravenous administration | Toxicity | Cytology | Cytotoxicity | Superoxide dismutase | Drug delivery | Kinases | Cyclin B1 | Silicon dioxide | Signal transduction | Mitochondria | Peroxidase | Membrane potential | Damage | Heart diseases | Deoxyribonucleic acid--DNA | Glutathione | Glutathione peroxidase | Outdoor air quality | Oxygen | CHK1 protein | Lactate dehydrogenase | Exposure | Hazards | Malondialdehyde | L-Lactate dehydrogenase | Endothelial cells | Signaling | Lactic acid | Mutation | Gene therapy | Cardiovascular diseases | Apoptosis | Deoxyribonucleic acid
Journal Article
Experimental dermatology, ISSN 1600-0625, 2009, Volume 18, Issue 6, pp. 553 - 561
:  Solar ultraviolet (UV) radiation, particularly its UVB (290–320 nm) component, is the primary cause of many adverse biological effects including photoageing and skin cancer... 
ultraviolet radiation | photoageing | human reconstituted skin | matrix metalloproteinases | DNA damage | pomegranate | Photoageing | Ultraviolet radiation | Matrix metalloproteinases | Human reconstituted skin | Pomegranate | CUTANEOUS CARCINOGENESIS | CELL NUCLEAR ANTIGEN | DNA-DAMAGE | INDUCED OXIDATIVE DAMAGE | KAPPA-B | RADIATION-INDUCED IMMUNOSUPPRESSION | DERMATOLOGY | PUNICA-GRANATUM POMEGRANATE | BOTANICAL ANTIOXIDANTS | DERMAL FIBROBLASTS | HUMAN EPIDERMAL-KERATINOCYTES | Matrix Metalloproteinases - genetics | Keratinocytes - radiation effects | Plant Extracts - pharmacology | Skin - metabolism | Coculture Techniques | Humans | Proto-Oncogene Proteins c-jun - biosynthesis | Proto-Oncogene Proteins c-fos - biosynthesis | Male | Protein Processing, Post-Translational - drug effects | Enzyme Induction - drug effects | Radiation-Protective Agents - pharmacology | Radiation-Protective Agents - isolation & purification | Oxidative Stress - radiation effects | Phosphorylation - drug effects | Drug Evaluation, Preclinical | Infant, Newborn | Matrix Metalloproteinases - biosynthesis | Organoids - radiation effects | DNA Damage - drug effects | Punicaceae - chemistry | Plant Oils - pharmacology | Protein Processing, Post-Translational - radiation effects | Plant Extracts - isolation & purification | Plant Oils - isolation & purification | Tropoelastin - biosynthesis | Ultraviolet Rays - adverse effects | Phosphorylation - radiation effects | Fibroblasts - radiation effects | Keratinocytes - drug effects | Tropoelastin - genetics | Skin - radiation effects | Fibroblasts - drug effects | Organoids - drug effects | Proto-Oncogene Proteins c-fos - genetics | Oxidative Stress - drug effects | DNA Damage - radiation effects | Enzyme Induction - radiation effects | Skin - drug effects | Antioxidants | Immunohistochemistry | Carbocyclic compounds | Anthocyanin | Tannins | Pyrimidines | DNA | Guanosine | Radiation | Chromophores | Skin cancer
Journal Article
PloS one, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0134110
.... Inhibitors of the DNA damage response are candidate drugs for use in combination therapies to increase the efficacy of such treatments... 
CANCER-CELLS | MULTIDISCIPLINARY SCIENCES | SYNTHETICALLY LETHAL | DOUBLE-STRAND BREAKS | CHECKPOINT | HOMOLOGOUS RECOMBINATION | AUTOPHAGY | REPAIR PATHWAYS | SACCHAROMYCES-CEREVISIAE | RAD52 INACTIVATION | HISTONE DEACETYLASE | DNA Damage - drug effects | DNA Repair - drug effects | Apoptosis - drug effects | Saccharomyces cerevisiae - genetics | Curcumin - pharmacology | Histone Deacetylases - chemistry | Immunoblotting | Saccharomyces cerevisiae - drug effects | Drug Resistance - drug effects | Saccharomyces cerevisiae - metabolism | Acetylation - drug effects | Chromatin Immunoprecipitation | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Histone Deacetylase Inhibitors - pharmacology | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Chemotherapy | Ionizing radiation | DNA damage | DNA | DNA repair | Cancer | Apoptosis | Drugs | Histone deacetylase | Biotechnology | Phosphorylation | Baking yeast | Yeast | Genes | Recombinase | Drug development | Kinases | Autophagy | Cancer therapies | Proteins | Cell cycle | Curcumin | Inhibition | Repair | Deoxyribonucleic acid--DNA | Rad52 protein | Biodegradation | Medical research | Immunoglobulins | Radiation therapy | Mammals | Double-strand break repair | Mutants | Sensitivity | Microscopy | Natural products | Phagocytosis | Deoxyribonucleic acid
Journal Article
Brain Research, ISSN 0006-8993, 2009, Volume 1311, pp. 189 - 196
Journal Article
Cell stem cell, ISSN 1934-5909, 06/2015, Volume 16, Issue 6, pp. 684 - 698
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 11/2010, Volume 107, Issue 46, pp. 20003 - 20008
...) in transformed cells (LNCaP, MCF-7), an effect not observed in normal cells (human foreskin fibroblast cells... 
Cell culture techniques | Histone deacetylase inhibitors | Cell death | DNA damage | DNA | Cell lines | Histones | Cultured cells | Viability | Apoptosis | DDIT3/CHOP/GADD153 | Chk2 | γH2AX | PROTEIN | CANCER CELLS | ACETYLATION | MULTIDISCIPLINARY SCIENCES | apoptosis | CHAPERONE FUNCTION | VORINOSTAT | histones | PHARMACOKINETICS | gamma H2AX | PERSPECTIVES | PROTEASOME | LYMPHOMA | STRESS | DNA Replication - drug effects | Humans | G1 Phase - drug effects | Neoplasm Proteins - metabolism | Caspases - metabolism | Cell Transformation, Neoplastic - genetics | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Hydroxamic Acids - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Histone Deacetylase 6 | Etoposide - pharmacology | Histone Deacetylases - metabolism | Topoisomerase II Inhibitors - pharmacology | Down-Regulation - drug effects | Drug Synergism | Up-Regulation - drug effects | Anilides - pharmacology | Cell Line, Tumor | Checkpoint Kinase 2 | Histone Deacetylase Inhibitors - pharmacology | Cell Transformation, Neoplastic - drug effects | DNA Damage | Histones - metabolism | Cell Transformation, Neoplastic - pathology | Doxorubicin - pharmacology | Drug Screening Assays, Antitumor | Antimitotic agents | Genetic aspects | Research | Properties | Antineoplastic agents | Biological Sciences | DDIT3 | GADD153 | CHOP
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 550, Issue 7677, pp. 475 - 480
.... Here we report a prolonged memory to acute inflammation that enables mouse EpSCs to hasten barrier restoration after subsequent tissue damage... 
AIM2 INFLAMMASOME | MODEL | RNA | CANCER | MULTIDISCIPLINARY SCIENCES | WOUND REPAIR | Inflammation - chemically induced | Inflammation - pathology | Skin - cytology | Epithelial Cells - metabolism | Inflammasomes - metabolism | Imiquimod | Epithelial Cells - drug effects | Caspase 1 - metabolism | Stem Cells - cytology | Macrophages | Stem Cells - metabolism | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Interleukin-1beta - metabolism | Regeneration - genetics | Female | Epigenesis, Genetic - drug effects | Wound Healing - genetics | Epithelial Cells - cytology | Aminoquinolines - pharmacology | Autoimmune Diseases - pathology | Wound Healing - drug effects | Skin - pathology | Skin - immunology | T-Lymphocytes | Stress, Physiological - genetics | Inflammation - immunology | DNA-Binding Proteins - genetics | Cell Lineage | Regeneration - drug effects | Animals | Epigenesis, Genetic - genetics | Inflammation - genetics | Stem Cells - drug effects | Mice | Wound Healing - physiology | Neoplasms - pathology | Chromatin - genetics | Skin - drug effects | Disease susceptibility | Skin | Inflammation | T cells | Stem cells | Genes | Interleukin | Homeostasis | Stem cell transplantation | Caspase | Lymphocytes T | Genomes | Cancer therapies | Caspase-1 | Excitatory postsynaptic potentials | Allografts | Lymphocytes | Sensitivity enhancement | Deoxyribonucleic acid--DNA | Cancer | Apoptosis
Journal Article