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Nature cell biology, ISSN 1476-4679, 2009, Volume 11, Issue 8, pp. 973 - 979
...), which initiate increased secretion of inflammatory cytokines such as interleukin-6 (IL-6). Cytokine secretion occurred only after establishment of persistent DNA damage... 
ROLES | HUMAN-CELLS | BARRIER | HUMAN FIBROBLASTS | GROWTH-FACTOR | ONCOGENE-INDUCED SENESCENCE | CELLULAR SENESCENCE | CANCER | TUMORIGENESIS | P53 | CELL BIOLOGY | RNA, Small Interfering - genetics | Humans | Male | Green Fluorescent Proteins - genetics | Tumor Suppressor Protein p53 - genetics | DNA-Binding Proteins - metabolism | Telomerase - genetics | Transfection | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Telomerase - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Telomere - genetics | Cell Line | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Enzyme-Linked Immunosorbent Assay | Cell Cycle Proteins - metabolism | Cells, Cultured | Cytokines - secretion | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Cellular Senescence - physiology | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Nuclear Proteins - metabolism | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Interleukin-6 - secretion | Blotting, Western | Fibroblasts - radiation effects | Checkpoint Kinase 2 | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Signal Transduction - physiology | Fibroblasts - cytology | DNA Damage | Microscopy, Fluorescence | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Cytokines | DNA damage
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 330, Issue 6009, pp. 1385 - 1389
Journal Article
PLoS genetics, ISSN 1553-7404, 2012, Volume 8, Issue 7, p. e1002772
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 27, pp. E3495 - E3504
Damage repair mechanisms at transcriptionally active sites during the G0/G1 phase are largely unknown... 
Dna damage | Recombination | CSB | Transcription | RNA polymerase II | COMPLEX | recombination | PROTEIN | transcription | DNA damage | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | DOUBLE-STRAND BREAKS | PREFERENTIAL REPAIR | CHROMOSOMES | 8-OXOGUANINE | GENE | DEGRADATION | Cell Cycle - genetics | Antigens, Nuclear - metabolism | Humans | DNA Repair Enzymes - genetics | Homologous Recombination | RNA - genetics | Cockayne Syndrome - pathology | DNA-Binding Proteins - metabolism | Poly-ADP-Ribose Binding Proteins | RNA Interference | Rad52 DNA Repair and Recombination Protein - metabolism | Replication Protein A - genetics | DNA Repair Enzymes - metabolism | HEK293 Cells | Cell Cycle Proteins - genetics | Transcription, Genetic | G1 Phase - genetics | Nuclear Proteins - genetics | DNA Helicases - genetics | RNA - metabolism | Rad51 Recombinase - metabolism | Rad51 Recombinase - genetics | Cockayne Syndrome - metabolism | Cell Cycle Proteins - metabolism | Cells, Cultured | Nuclear Proteins - metabolism | Replication Protein A - metabolism | DNA-Binding Proteins - genetics | Blotting, Western | Rad52 DNA Repair and Recombination Protein - genetics | DNA Helicases - metabolism | Microscopy, Confocal | Antigens, Nuclear - genetics | Resting Phase, Cell Cycle - genetics | Ku Autoantigen | DNA Repair | Cockayne Syndrome - genetics | Cell Line, Tumor | Models, Genetic | DNA Damage | HeLa Cells | Physiological aspects | Observations | Genetic recombination | RNA polymerases | Biological Sciences | PNAS Plus
Journal Article
Nature (London), ISSN 1476-4687, 2005, Volume 434, Issue 7035, pp. 864 - 870
... ( but not normal tissues) commonly express markers of an activated DNA damage response. These include phosphorylated kinases ATM and Chk2, and phosphorylated histone H2AX and p53... 
GENOMIC INSTABILITY | BREAST-CANCER | CHROMOSOME INSTABILITY | REPLICATION | PROTEIN | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | HISTONE H2AX | ATM | CELL-CYCLE CONTROL | P53 | Allelic Imbalance - genetics | Genomic Instability | Phosphorylation | Humans | Urinary Bladder Neoplasms - enzymology | E2F Transcription Factors | Neoplasms - prevention & control | Oncogenes - physiology | Cyclin E - genetics | DNA-Binding Proteins - metabolism | Urinary Bladder Neoplasms - genetics | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Urinary Bladder Neoplasms - pathology | Cell Cycle Proteins - genetics | DNA Damage - genetics | cdc25 Phosphatases - metabolism | Urinary Bladder Neoplasms - metabolism | Protein-Serine-Threonine Kinases - metabolism | Oncogenes - genetics | Signal Transduction | Cell Cycle Proteins - metabolism | Neoplasms - enzymology | cdc25 Phosphatases - genetics | Genes, p53 - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Transcription Factors - metabolism | Cell Cycle | Cell Line, Tumor | Checkpoint Kinase 2 | Polymorphism, Single Nucleotide - genetics | Cyclin E - metabolism | Enzyme Activation | Neoplasms - pathology | Deoxyribonucleic acid | DNA | Genomics | Cell division | Gene expression | Cancer | Tumors
Journal Article