UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4902) 4902
Book Chapter (58) 58
Newspaper Article (20) 20
Newsletter (10) 10
Magazine Article (6) 6
Book / eBook (5) 5
Dissertation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (3979) 3979
life sciences & biomedicine (3412) 3412
microbiology (1849) 1849
biochemistry & molecular biology (1394) 1394
humans (1112) 1112
bacteria (1080) 1080
dna (1021) 1021
mutation (978) 978
deoxyribonucleic acid--dna (964) 964
molecular sequence data (905) 905
escherichia coli - genetics (826) 826
research article (767) 767
anti-bacterial agents - pharmacology (756) 756
animals (754) 754
proteins (748) 748
dna gyrase - genetics (720) 720
dna topoisomerases, type ii - metabolism (697) 697
bacterial proteins - genetics (695) 695
microbial sensitivity tests (695) 695
research (666) 666
pharmacology & pharmacy (661) 661
bacterial proteins - metabolism (660) 660
base sequence (645) 645
dna gyrase - metabolism (636) 636
dna, bacterial - genetics (612) 612
genes (592) 592
science & technology - other topics (542) 542
multidisciplinary sciences (539) 539
biochemical phenomena, metabolism, and nutrition (535) 535
analysis (519) 519
genetic aspects (511) 511
enzymes (501) 501
dna, bacterial - metabolism (479) 479
plasmids (479) 479
gene expression (478) 478
genomes (475) 475
amino acid sequence (473) 473
antibiotics (461) 461
dna replication (456) 456
escherichia coli - enzymology (451) 451
dna gyrase (431) 431
e coli (417) 417
sequence analysis, dna (417) 417
escherichia coli - metabolism (414) 414
dna, superhelical - metabolism (411) 411
escherichia coli (406) 406
phylogeny (404) 404
life sciences (403) 403
genomics (402) 402
dna topoisomerases, type ii - genetics (397) 397
deoxyribonucleic acid (387) 387
binding sites (382) 382
models, molecular (381) 381
cell biology (380) 380
nucleic acid conformation (380) 380
dna - metabolism (368) 368
anti-infective agents - pharmacology (367) 367
topoisomerase ii inhibitors (364) 364
protein binding (359) 359
dna topoisomerases, type i - metabolism (353) 353
medicine (353) 353
physiological aspects (347) 347
drug resistance (346) 346
gene expression regulation, bacterial (337) 337
dna, bacterial - chemistry (334) 334
bacterial infections and mycoses (333) 333
genes, bacterial (323) 323
infectious diseases (323) 323
dna-binding proteins - metabolism (322) 322
genetics (322) 322
biochemistry (317) 317
escherichia coli - drug effects (315) 315
science (313) 313
biotechnology & applied microbiology (297) 297
ciprofloxacin - pharmacology (286) 286
bacteriology (282) 282
biology (274) 274
dna repair (271) 271
fluoroquinolones - pharmacology (263) 263
dna topoisomerase (261) 261
polymerase chain reaction (261) 261
kinetics (259) 259
genetics & heredity (257) 257
transcription, genetic (257) 257
dna damage (253) 253
rna (252) 252
fluoroquinolones (251) 251
molecular biology (248) 248
drug resistance, bacterial - genetics (242) 242
dna topoisomerase iv - genetics (238) 238
adenosine triphosphate - metabolism (233) 233
chromosomes (233) 233
escherichia coli proteins - metabolism (225) 225
genetic research (224) 224
chemistry (218) 218
drug resistance, bacterial (215) 215
structure-activity relationship (215) 215
plasmids - genetics (214) 214
dna - chemistry (212) 212
biotechnology (207) 207
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4986) 4986
Japanese (24) 24
Russian (15) 15
Portuguese (14) 14
German (6) 6
Spanish (4) 4
Chinese (3) 3
French (3) 3
Polish (3) 3
Danish (1) 1
Dutch (1) 1
Italian (1) 1
Norwegian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The Journal of biological chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12300 - 12312
Background: X-ray crystal structures of fluoroquinolone-gyrase-DNA complexes reveal a single drug-binding mode. Results... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Fluoroquinolones - chemistry | DNA, Bacterial - metabolism | Escherichia coli - drug effects | Crystallography, X-Ray | DNA, Bacterial - chemistry | Macromolecular Substances - pharmacology | Microbial Sensitivity Tests | Fluoroquinolones - metabolism | Macromolecular Substances - chemistry | Topoisomerase II Inhibitors - chemistry | Anti-Bacterial Agents - chemistry | DNA Topoisomerases, Type II - chemistry | Molecular Structure | Nucleic Acid Conformation | Ciprofloxacin - metabolism | Protein Structure, Tertiary | DNA Topoisomerases, Type II - metabolism | Escherichia coli - enzymology | DNA Gyrase - chemistry | Ciprofloxacin - pharmacology | Models, Molecular | Anti-Bacterial Agents - metabolism | Escherichia coli Proteins - metabolism | Topoisomerase II Inhibitors - pharmacology | Topoisomerase II Inhibitors - metabolism | DNA Gyrase - metabolism | DNA, Bacterial - genetics | DNA Gyrase - genetics | Escherichia coli - genetics | Fluoroquinolones - pharmacology | Mycobacterium smegmatis - drug effects | Ciprofloxacin - chemistry | Escherichia coli Proteins - genetics | Protein Binding | DNA Topoisomerases, Type II - genetics | Anti-Bacterial Agents - pharmacology | Mutation | Escherichia coli Proteins - chemistry | Macromolecular Substances - metabolism | Index Medicus | DNA and Chromosomes | Enzyme Inhibitors | Bacterium | Antibiotic Action | Cleaved Complexes | Cross-linking | Escherichia coli | DNA Topoisomerase | Resistance Mutations | Mycobacterium smegmatis | Bacteria
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 22, pp. 18636 - 18644
DNA topoisomerases manage chromosome supercoiling and organization in all cells. Gyrase, a prokaryotic type IIA topoisomerase, consumes ATP to introduce negative supercoils through a strand passage mechanism... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Hydrolysis | Sequence Homology, Amino Acid | Amino Acid Sequence | DNA Gyrase - metabolism | Catalytic Domain | Escherichia coli - enzymology | DNA Gyrase - chemistry | Adenosine Triphosphate - metabolism | Base Sequence | Molecular Sequence Data | DNA Primers | Index Medicus
Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 09/2015, Volume 12, Issue 9, pp. 1497 - 1507
Journal Article
Journal Article
Journal Article