Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (17074) 17074
Book Chapter (349) 349
Newsletter (131) 131
Newspaper Article (111) 111
Dissertation (17) 17
Book / eBook (8) 8
Magazine Article (6) 6
Conference Proceeding (3) 3
Reference (2) 2
Streaming Video (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (14011) 14011
life sciences & biomedicine (11149) 11149
humans (6459) 6459
animals (5027) 5027
proteins (4867) 4867
biochemistry & molecular biology (4650) 4650
deoxyribonucleic acid--dna (4324) 4324
dna (3559) 3559
gene expression (3355) 3355
dna repair (3150) 3150
cell biology (3091) 3091
research (2980) 2980
genes (2746) 2746
science & technology - other topics (2722) 2722
multidisciplinary sciences (2667) 2667
molecular sequence data (2630) 2630
dna damage (2618) 2618
mutation (2596) 2596
research article (2583) 2583
genomes (2439) 2439
enzymes (2428) 2428
genetic aspects (2411) 2411
base sequence (2367) 2367
analysis (2162) 2162
biological and medical sciences (2112) 2112
physiological aspects (2024) 2024
microbiology (1853) 1853
genetics & heredity (1845) 1845
genetics (1823) 1823
genomics (1779) 1779
biochemistry (1663) 1663
fundamental and applied biological sciences. psychology (1661) 1661
amino acid sequence (1649) 1649
life sciences (1643) 1643
biology (1634) 1634
mice (1600) 1600
cancer (1597) 1597
medicine (1563) 1563
science (1502) 1502
kinases (1494) 1494
dna-binding proteins - metabolism (1486) 1486
cell cycle (1397) 1397
apoptosis (1353) 1353
deoxyribonucleic acid (1341) 1341
signal transduction (1317) 1317
protein binding (1283) 1283
mitochondrial dna (1276) 1276
phosphorylation (1243) 1243
oncology (1226) 1226
metabolism (1188) 1188
dna replication (1186) 1186
rna (1171) 1171
molecular biology (1139) 1139
genetic research (1119) 1119
ligases (1118) 1118
dna-binding proteins - genetics (1072) 1072
female (1072) 1072
mitochondria (1048) 1048
male (1045) 1045
plant sciences (1042) 1042
biotechnology (1026) 1026
dna - metabolism (1017) 1017
binding sites (1006) 1006
polymerase chain reaction (1001) 1001
transcription (989) 989
biotechnology & applied microbiology (987) 987
cell line (976) 976
sequence analysis, dna (965) 965
bacteria (943) 943
transcription factors (921) 921
health aspects (919) 919
dna methylation (914) 914
chromatin (897) 897
dna ligases - metabolism (887) 887
review (881) 881
ubiquitin (868) 868
cloning, molecular (867) 867
plasmids (866) 866
ribonucleic acid--rna (858) 858
amino acids (853) 853
dna ligase atp (819) 819
chemistry (816) 816
oxidative stress (783) 783
transcription, genetic (771) 771
genetic transcription (731) 731
escherichia coli - genetics (728) 728
cell line, tumor (716) 716
physical sciences (711) 711
gene expression profiling (709) 709
tumors (708) 708
biosynthesis (705) 705
chromosomes (683) 683
biochemistry, general (678) 678
phylogeny (671) 671
transcription factors - metabolism (658) 658
kinetics (656) 656
dna - genetics (654) 654
fungi (637) 637
dna binding proteins (627) 627
dna - chemistry (619) 619
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (17686) 17686
Japanese (46) 46
Russian (17) 17
German (14) 14
Chinese (13) 13
Portuguese (6) 6
Norwegian (5) 5
Spanish (5) 5
French (3) 3
Italian (2) 2
Czech (1) 1
Dutch (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates
by Unciuleac, Mihaela-Carmen and Goldgur, Yehuda and Shuman, Stewart and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
The Journal of biological chemistry, ISSN 0021-9258, 03/2019, Volume 294, Issue 13, pp. 5094 - 5104
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Catalytic Domain | Humans | Bacterial Proteins - chemistry | Models, Molecular | Crystallography, X-Ray | Magnesium - metabolism | Tuberculosis - microbiology | DNA Ligases - metabolism | Sequence Alignment | Adenosine Triphosphate - metabolism | Protein Domains | Bacterial Proteins - metabolism | Mycobacterium tuberculosis - chemistry | Protein Conformation | Mycobacterium tuberculosis - metabolism | DNA Ligases - chemistry | Index Medicus | DNA ligase | lysyl–AMP | Mycobacterium tuberculosis | BASIC BIOLOGICAL SCIENCES | covalent nucleotidyltransferase | catalysis | DNA repair | ATP | two metal mechanism | enzyme structure | metal ion-protein interaction | DNA and Chromosomes
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor
by Howes, Timothy R.L and Sallmyr, Annahita and Brooks, Rhys and Greco, George E and Jones, Darin E and Matsumoto, Yoshihiro and Tomkinson, Alan E
DNA repair, ISSN 1568-7864, 12/2017, Volume 60, pp. 29 - 39
Michaelis-Menten kinetics | DNA replication | Enzyme-substrate complex | Nucleotidyl transfer | Phosphodiester bond formation | Toxicology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Humans | Enzyme Inhibitors - pharmacology | DNA Ligase ATP - metabolism | DNA Replication | DNA Ligase ATP - antagonists & inhibitors | Structure-Activity Relationship | Kinetics | Pyridazines - pharmacology | Pyridazines - chemical synthesis | Enzyme kinetics | Ligases | Analysis | DNA | Cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Altered DNA ligase activity in human disease
by Tomkinson, Alan E and Naila, Tasmin and Khattri Bhandari, Seema
Mutagenesis, ISSN 0267-8357, 02/2020, Volume 35, Issue 1, pp. 51 - 60
Toxicology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Disease - genetics | Immunologic Deficiency Syndromes - etiology | Poly-ADP-Ribose Binding Proteins - metabolism | Humans | Poly-ADP-Ribose Binding Proteins - genetics | Animals | Neoplasms - genetics | DNA Ligase ATP - genetics | DNA Repair | DNA Ligase ATP - metabolism | DNA Ligase ATP - antagonists & inhibitors | Mice | DNA Damage | Index Medicus | Reviews
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Structural bias in T4 RNA ligase-mediated 3′-adapter ligation
by Zhuang, Fanglei and Fuchs, Ryan T and Sun, Zhiyi and Zheng, Yu and Robb, G. Brett
Nucleic acids research, ISSN 0305-1048, 04/2012, Volume 40, Issue 7, pp. e54 - e54
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | RNA Folding | Oligonucleotides - chemistry | RNA Ligase (ATP) - metabolism | MicroRNAs - metabolism | RNA - chemistry | Viral Proteins - metabolism | Animals | Sequence Analysis, RNA | High-Throughput Nucleotide Sequencing | Mice | Nucleic Acid Conformation | MicroRNAs - chemistry | RNA - metabolism | Index Medicus | RNA ligase | Nucleotide sequence | DNA | miRNA | Nucleotides | Quantitation | Secondary structure | Protein structure | DNA sequencing | Methods Online
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation
by Simsek, Deniz and Jasin, Maria
Nature structural & molecular biology, ISSN 1545-9993, 04/2010, Volume 17, Issue 4, pp. 410 - 416
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | DNA-Binding Proteins - metabolism | Translocation, Genetic | DNA Repair | Humans | DNA Ligase ATP | DNA-Binding Proteins - genetics | DNA Ligases - metabolism | Physiological aspects | Genetic aspects | Research | Translocation (Genetics) | Ligases | Stem cells | Cell division | Chromosomes | Index Medicus | ligase IV | alternative NHEJ | DNA double-strand break | nonhomologous end-joining | Xrcc4 | chromosomal translocation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis
by Kaminski, Andrea M and Tumbale, Percy P and Schellenberg, Matthew J and Williams, R. Scott and Williams, Jason G and Kunkel, Thomas A and Pedersen, Lars C and Bebenek, Katarzyna and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2642 - 12
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Catalytic Domain | Biocatalysis | Humans | Mutagenesis - genetics | Substrate Specificity | DNA - metabolism | Mutation - genetics | Polymorphism, Genetic | DNA Ligase ATP - genetics | Base Sequence | DNA Ligase ATP - chemistry | DNA Ligase ATP - metabolism | Protein Binding | Adenine - metabolism | Lysine - metabolism | AMP | DNA damage | Genotoxicity | Immunodeficiency | Radiation | DNA ligase (ATP) | Nucleic acids | Sealing | DNA repair | Substrates | Mutagenesis | Catalysis | Mutation | Deoxyribonucleic acid--DNA | LIG4 protein | Crystal structure | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation
by Ferry, Laure and Fournier, Alexandra and Tsusaka, Takeshi and Adelmant, Guillaume and Shimazu, Tadahiro and Matano, Shohei and Kirsh, Olivier and Amouroux, Rachel and Dohmae, Naoshi and Suzuki, Takehiro and Filion, Guillaume J and Deng, Wen and de Dieuleveult, Maud and Fritsch, Lauriane and Kudithipudi, Srikanth and Jeltsch, Albert and Leonhardt, Heinrich and Hajkova, Petra and Marto, Jarrod A and Arita, Kyohei and Shinkai, Yoichi and Defossez, Pierre-Antoine
Molecular cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 4, pp. 550 - 565.e5
DNA methylation | DNA replication | G9a(Ehmt2)/GLP(Ehmt1) | UHRF1 | epigenetics | lysine methylation | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Histocompatibility Antigens - genetics | Epigenesis, Genetic | Humans | Histocompatibility Antigens - chemistry | Structure-Activity Relationship | DNA Methylation | Molecular Mimicry | Transfection | DNA Ligase ATP - genetics | HEK293 Cells | DNA Ligase ATP - metabolism | DNA - biosynthesis | CCAAT-Enhancer-Binding Proteins - genetics | Histocompatibility Antigens - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | Histone-Lysine N-Methyltransferase - genetics | Models, Molecular | DNA Replication | Embryonic Stem Cells - enzymology | Tudor Domain | DNA - genetics | Histone-Lysine N-Methyltransferase - chemistry | Animals | Histone-Lysine N-Methyltransferase - metabolism | Lysine | DNA Ligase ATP - chemistry | Protein Binding | Protein Conformation | CCAAT-Enhancer-Binding Proteins - chemistry | Mice | Protein Processing, Post-Translational | HeLa Cells | Histones - metabolism | Mutation | Methylation | Epigenetic inheritance | Ligases | Analysis | DNA | Methyltransferases | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Ligase 3–mediated end‐joining maintains genome stability of human embryonic stem cells
by Kohutova, Aneta and Raška, Jan and Kruta, Miriama and Seneklova, Monika and Barta, Tomas and Fojtik, Petr and Jurakova, Tereza and Walter, Christi A and Hampl, Ales and Dvorak, Petr and Rotrekl, Vladimir
The FASEB journal, ISSN 0892-6638, 06/2019, Volume 33, Issue 6, pp. 6778 - 6788
base excision repair | PARP1 | pluripotent stem cells | 53BP1 | alternative DNA end-joining | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genomic Instability | Poly-ADP-Ribose Binding Proteins - metabolism | DNA End-Joining Repair - radiation effects | Human Embryonic Stem Cells - cytology | Humans | Cells, Cultured | DNA Repair - physiology | DNA Repair - radiation effects | Poly-ADP-Ribose Binding Proteins - genetics | Homologous Recombination | DNA End-Joining Repair - physiology | DNA Breaks, Double-Stranded - radiation effects | DNA Ligase ATP - genetics | Human Embryonic Stem Cells - physiology | DNA Ligase ATP - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights