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Biochimica et biophysica acta. Molecular cell research, ISSN 0167-4889, 01/2014, Volume 1843, Issue 1, pp. 75 - 85
Slx5 | Arkadia | Rnf4 | Uls1 | SIM | Slx8 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | DNA Damage - physiology | Proteolysis | Humans | DNA Repair - physiology | Ubiquitin-Protein Ligases - metabolism | Genomic Instability - physiology | Saccharomyces cerevisiae - enzymology | Sumoylation | Schizosaccharomyces - enzymology | SUMO-1 Protein - metabolism | Yeasts - enzymology | Post-translational modification | Ubiquitin | Sumo | Ligases | DNA repair
Journal Article
Nature (London), ISSN 0028-0836, 03/2016, Volume 531, Issue 7596, pp. 598 - 603
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Apoproteins - chemistry | Cullin Proteins - ultrastructure | Allosteric Regulation | Humans | Apoproteins - ultrastructure | Crystallography, X-Ray | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Ubiquitination | Cullin Proteins - metabolism | Carrier Proteins - chemistry | Binding Sites | Ubiquitins - metabolism | Apoproteins - metabolism | Peptide Hydrolases - metabolism | Biocatalysis | Carrier Proteins - ultrastructure | Models, Molecular | COP9 Signalosome Complex | DNA-Binding Proteins - chemistry | Peptide Hydrolases - chemistry | Cryoelectron Microscopy | Cullin Proteins - chemistry | DNA-Binding Proteins - ultrastructure | Multiprotein Complexes - ultrastructure | Multiprotein Complexes - chemistry | Carrier Proteins - metabolism | Peptide Hydrolases - ultrastructure | Protein Binding | DNA Damage | Kinetics | Ubiquitin | Genetic research | Research | DNA repair | Proteins | Enzymes | Mutation | Binding sites | Deoxyribonucleic acid--DNA | Index Medicus
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Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
Nature (London), ISSN 0028-0836, 2012, Volume 488, Issue 7413, pp. 665 - 669
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Oncogene Proteins - genetics | Receptors, Wnt - antagonists & inhibitors | Cell Proliferation | Receptors, G-Protein-Coupled - metabolism | Humans | Ubiquitin - metabolism | Paneth Cells - pathology | Stem Cells - cytology | Receptors, Wnt - metabolism | Stem Cells - metabolism | DNA-Binding Proteins - deficiency | Adenoma - metabolism | DNA-Binding Proteins - metabolism | Endocytosis | Ubiquitination | Lysosomes - metabolism | Stem Cells - enzymology | Tumor Suppressor Proteins - deficiency | Organoids - metabolism | Tumor Suppressor Proteins - genetics | HEK293 Cells | Colorectal Neoplasms - metabolism | Paneth Cells - metabolism | Tumor Suppressor Proteins - metabolism | Organoids - pathology | Oncogene Proteins - metabolism | Organoids - cytology | Ubiquitin-Protein Ligases - metabolism | Frizzled Receptors - metabolism | DNA-Binding Proteins - genetics | beta Catenin - metabolism | Animals | Wnt Signaling Pathway - drug effects | Adenoma - pathology | Ubiquitin-Protein Ligases - deficiency | Oncogene Proteins - deficiency | Mice | Receptors, G-Protein-Coupled - genetics | Colorectal Neoplasms - pathology | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Colorectal cancer | Physiological aspects | Development and progression | Research | Gene expression | Risk factors | Proteins | Epidermal growth factor | Mutation | Kinases | Rodents | Stem cells | Index Medicus
Journal Article
Nature (London), ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 49 - 53
Thalidomide - metabolism | Homeodomain Proteins - metabolism | Humans | Substrate Specificity | Ubiquitin-Protein Ligases - antagonists & inhibitors | Crystallography, X-Ray | Structure-Activity Relationship | Multiprotein Complexes - antagonists & inhibitors | DNA-Binding Proteins - metabolism | Multiprotein Complexes - metabolism | Thalidomide - analogs & derivatives | DNA-Binding Proteins - agonists | Peptide Hydrolases - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Lenalidomide | Thalidomide - chemistry | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Ubiquitin-Protein Ligases - chemistry | DNA-Binding Proteins - chemistry | Peptide Hydrolases - chemistry | Transcription Factors - metabolism | Multiprotein Complexes - chemistry | Protein Binding | Multiprotein Complexes - agonists | Protein research | Research | Properties | Ubiquitin-proteasome system | Ligases | Immunity | Proteins | Solvents | Transcription factors | Ligands | Mutation | Drug resistance | Pharmaceuticals | Index Medicus
Journal Article
Nature structural & molecular biology, ISSN 1545-9993, 07/2016, Volume 23, Issue 7, pp. 647 - 655
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Chromatin - metabolism | DNA, Neoplasm - metabolism | Humans | Gene Expression Regulation, Neoplastic | Ubiquitin - metabolism | DNA Breaks, Double-Stranded | Ubiquitination - drug effects | BRCA1 Protein - metabolism | Tumor Suppressor Proteins - genetics | Cloning, Molecular | Escherichia coli - metabolism | Binding Sites | Chromatin - drug effects | DNA Helicases - genetics | Chromatin - chemistry | Tumor Suppressor p53-Binding Protein 1 - metabolism | Recombinant Proteins - metabolism | Gene Expression | Recombinational DNA Repair | Tumor Suppressor Proteins - metabolism | Tumor Suppressor p53-Binding Protein 1 - genetics | Signal Transduction | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Recombinant Proteins - genetics | Ubiquitin - genetics | Piperazines - pharmacology | DNA Cleavage - drug effects | BRCA1 Protein - genetics | DNA Helicases - metabolism | Phthalazines - pharmacology | Histones - genetics | Escherichia coli - genetics | Protein Binding | DNA, Neoplasm - genetics | HeLa Cells | Histones - metabolism | Ubiquitin-Protein Ligases - genetics | Camptothecin - pharmacology | Breast cancer | BRCA mutations | DNA repair | Analysis | Risk factors | Enzymes | Protein expression | Chromatin | DNA damage | Index Medicus
Journal Article
The Plant cell, ISSN 1040-4651, 2/2014, Volume 26, Issue 2, pp. 695 - 711
Proteins | Yeasts | Receptors | Plant growth regulators | RESEARCH ARTICLES | Ubiquitins | Gene expression regulation | Plants | Regulator genes | Plant cells | Seedlings | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | Basic-Leucine Zipper Transcription Factors - metabolism | Arabidopsis - growth & development | Sodium Chloride - pharmacology | Adaptation, Physiological - drug effects | Molecular Sequence Data | Arabidopsis Proteins - metabolism | DNA-Binding Proteins - metabolism | Proteolysis - drug effects | Seeds - growth & development | Droughts | Germination - genetics | Protein Binding - drug effects | Cullin Proteins - metabolism | Plant Stomata - drug effects | Carrier Proteins - chemistry | Abscisic Acid - metabolism | Germination - drug effects | Amino Acid Sequence | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Seeds - drug effects | Seeds - genetics | Ubiquitin-Protein Ligases - metabolism | Signal Transduction - genetics | DNA-Binding Proteins - genetics | Arabidopsis - metabolism | Arabidopsis - genetics | Abscisic Acid - pharmacology | Gene Expression Regulation, Plant - drug effects | Carrier Proteins - metabolism | Substrate Specificity - drug effects | Arabidopsis Proteins - chemistry | Signal Transduction - drug effects | Protein Stability - drug effects | Plant Stomata - genetics | Plant Stomata - physiology | Arabidopsis thaliana | Protein research | Botanical research | Physiological aspects | Abscisic acid | Cellular signal transduction | Research | DNA binding proteins | Index Medicus | s
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2008, Volume 322, Issue 5901, pp. 597 - 602
Yeasts | Medical research | Nuclear pore | DNA damage | Ubiquitins | DNA | Imaging | Genetic loci | Reports | DNA repair | Genetic mutation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Molecular genetics | Mutagenesis. Repair | Immunoprecipitation | DNA, Fungal - genetics | Saccharomyces cerevisiae - genetics | Intracellular Signaling Peptides and Proteins - metabolism | DNA Breaks, Double-Stranded | DNA-Binding Proteins - metabolism | Nuclear Pore Complex Proteins - genetics | Saccharomyces cerevisiae - metabolism | Chromatin Immunoprecipitation | Recombination, Genetic | Genes, Fungal | Protein-Serine-Threonine Kinases - metabolism | Zinc Fingers | Nuclear Pore Complex Proteins - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Saccharomyces cerevisiae Proteins - genetics | DNA-Binding Proteins - genetics | Nuclear Pore - metabolism | Gene Conversion | Deoxyribonucleases, Type II Site-Specific - metabolism | DNA Repair | DNA, Fungal - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Kinetics | Physiological aspects | Cellular proteins | Genetic aspects | Research | Ligases | Biomedical research | Yeast | Gene expression | Genomics | Index Medicus
Journal Article
Nature reviews. Cancer, ISSN 1474-175X, 01/2018, Volume 18, Issue 2, pp. 69 - 88
Life Sciences & Biomedicine | Oncology | Science & Technology | Animals | Cell Proliferation | Neoplasms - genetics | Cell Transformation, Neoplastic | Humans | Ubiquitin - metabolism | Ubiquitin-Protein Ligases - metabolism | Neoplasms - enzymology | Neoplasms - physiopathology | Ubiquitin-Protein Ligases - genetics | Neoplasms - drug therapy | Care and treatment | Ligases | Tumor suppressor genes | Health aspects | Oncogenes | Methods | Cancer | Ubiquitin | Deregulation | Transformation | DNA damage | Homeostasis | Topology | Metabolism | Substrates | Cell cycle | Tumorigenesis | Localization | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
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