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Science, ISSN 0036-8075, 2014, Volume 343, Issue 6167, pp. 189 - 193
Tumor recurrence is a leading cause of cancer mortality. Therapies for recurrent disease may fail, at least in part, because the genomic alterations driving... 
RETINOBLASTOMA | IDH1 MUTATIONS | MULTIDISCIPLINARY SCIENCES | INTRATUMOR HETEROGENEITY | GROWTH | CLONAL EVOLUTION | MSH6 MUTATIONS | IDENTIFICATION | HUMAN CANCER | HUMAN-MALIGNANT GLIOMAS | TEMOZOLOMIDE | Studies | Brain surgery | Mutagenesis | Brain cancer | Clinical outcomes | temozolomide | Brain | TP53 protein, human | Humans | Neoplasm Recurrence, Local | BRAF protein, human | MTOR protein, human | Brain Neoplasms | Nuclear Proteins | Index Medicus | Proto-Oncogene Proteins c-akt | Dacarbazine | DNA Helicases | Neoplasm Grading | Tumor Suppressor Protein p53 | SMARCA4 protein, human | ATRX protein, human | Glioma | DNA Mutational Analysis | TOR Serine-Threonine Kinases | Transcription Factors | Proto-Oncogene Proteins B-raf | Antineoplastic Agents, Alkylating | Dacarbazine - adverse effects | Dacarbazine - therapeutic use | Brain Neoplasms - pathology | Neoplasm Recurrence, Local - drug therapy | X-linked Nuclear Protein | Mutagenesis - drug effects | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Glioma - genetics | TOR Serine-Threonine Kinases - genetics | Glioma - pathology | Dacarbazine - analogs & derivatives | Nuclear Proteins - genetics | DNA Helicases - genetics | Brain Neoplasms - genetics | Transcription Factors - genetics | Brain Neoplasms - drug therapy | Antineoplastic Agents, Alkylating - therapeutic use | Brain - drug effects | Proto-Oncogene Proteins B-raf - genetics | Neoplasm Recurrence, Local - chemically induced | Brain - pathology | Neoplasm Recurrence, Local - genetics | Antineoplastic Agents, Alkylating - adverse effects | Glioma - drug therapy | Care and treatment | Gene mutations | Gliomas | Physiological aspects | Genetic aspects | Research | Methods | Cancer
Journal Article
Leukemia, ISSN 0887-6924, 08/2016, Volume 30, Issue 8, pp. 1672 - 1681
Journal Article
Science, ISSN 0036-8075, 5/2004, Volume 304, Issue 5674, pp. 1164 - 1166
Tyrosine phosphorylation, regulated by protein tyrosine phosphatases (PTPs) and kinases (PTKs), is important in signaling pathways underlying tumorigenesis. A... 
Cell growth | Phosphorylation | Phosphatases | Genetic vectors | Genomics | Colorectal cancer | Reports | Gene expression regulation | Genetic mutation | Tumors | Cancer | BREAST-CANCER | CELLS | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | GROWTH | DISEASE | TUMOR-SUPPRESSOR GENE | BETA-CATENIN | IDENTIFICATION | KINASES | PTPRG | Tyrosine | Colorectal carcinoma | Tumor suppressor genes | Mutation | man | Protein-tyrosine kinase | Protein-tyrosine-phosphatase | Markov Chains | Frameshift Mutation | Exons | Genes | Humans | Amino acids | Biochemistry | Mutation, Missense | protein tyrosine phosphatase H1 | Protein-Tyrosine-Phosphatase | Transfection | DNA Mutational Analysis | Cell Division | Colorectal Neoplasms | PTPN13 protein, human | Genes, Tumor Suppressor | Catalytic Domain | Signal Transduction | Computational Biology | Nerve Tissue Proteins | Codon, Nonsense | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, P.H.S | receptor protein tyrosine phosphatase gamma | Kinetics | Human | Mutations | Article | Kinases | Suppressors | Proteins | Cellular | Alterations | Pathways | Lungs | Austenitic stainless steels | Copyrights | Documents | Breast | Colorectal Neoplasms - genetics | Protein Tyrosine Phosphatases - metabolism | Receptor-Like Protein Tyrosine Phosphatases, Class 5 | Nerve Tissue Proteins - chemistry | Protein Tyrosine Phosphatases - chemistry | Protein Tyrosine Phosphatases - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 13 | Colorectal Neoplasms - enzymology | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Tyrosine - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 3 | Research | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 2014, Volume 5, Issue 13, pp. 5065 - 5075
Little is known about the genomic basis of primary central nervous system lymphoma (PCNSL) tumorigenesis. To investigate the mutational profile of PCNSL, we... 
Primary CNS lymphoma | B cell differentiation | NFKB | Somatic mutations | Exome sequencing | SURVIVAL | ACTIVATION | GENOME | FAMILY | CELL BIOLOGY | somatic mutations | GENETIC-VARIATION | exome sequencing | B-CELL LYMPHOMA | DATABASE | ONCOLOGY | ROLES | DIFFERENTIATION | EXPRESSION | Index Medicus
Journal Article
Cancer, ISSN 0008-543X, 05/2014, Volume 120, Issue 10, pp. 1482 - 1490
In this study, NRAS mutations were observed almost exclusively in rectal cancers compared with colon cancers. This result suggests that there may be a biologic... 
mutation | NRAS | BRAF | colorectal cancer | clinicopathologic | ASSOCIATIONS | CODON 12 | COLON-CANCER | RECTAL-CANCER | CIGARETTE-SMOKING | POLYMORPHISMS | ONCOLOGY | TUMOR SITE | CARCINOMAS | KRAS | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Rectal Neoplasms - chemistry | Gene Expression Profiling | Tumor Suppressor Protein p53 - genetics | Proto-Oncogene Proteins B-raf - analysis | Rectal Neoplasms - genetics | DNA Mutational Analysis | Aged, 80 and over | Adult | Colonic Neoplasms - chemistry | Female | Adenocarcinoma - genetics | Rectal Neoplasms - pathology | Retrospective Studies | Adenocarcinoma - chemistry | Adenomatous Polyposis Coli Protein - genetics | Colonic Neoplasms - mortality | Biomarkers, Tumor - analysis | Membrane Proteins - genetics | Risk Factors | Kaplan-Meier Estimate | Genotype | Proto-Oncogene Proteins - genetics | Adenocarcinoma - secondary | Rectal Neoplasms - mortality | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | GTP Phosphohydrolases - genetics | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Mutation | Neoplasm Staging | Adenocarcinoma - mortality | Care and treatment | Usage | Colorectal cancer | Genetic aspects | Metastasis | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
Science, ISSN 0036-8075, 5/2003, Volume 300, Issue 5621, pp. 949 - 949
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2009, Volume 54, Issue 22, pp. 2065 - 2074
Journal Article