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Science, ISSN 0036-8075, 4/2012, Volume 336, Issue 6079, pp. 315 - 319
A detailed understanding of the mechanisms that underlie antibiotic killing is important for the derivation of new classes of antibiotics and clinically useful... 
RESEARCH ARTICLE | Antibiotics | Cell death | DNA | Fluorescence | Cytotoxicity | Oxidation | Nucleotides | Overproduction | Genetic mutation | Guanine nucleotides | MUTAGENESIS | PROTEIN | REPLICATION | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | DOUBLE-STRAND BREAKS | HYDROGEN-PEROXIDE | MECHANISMS | MUTT-TYPE ENZYME | DNA-POLYMERASES | DAMAGE | Guanine Nucleotides - metabolism | DNA, Bacterial - metabolism | Guanine - analogs & derivatives | Escherichia coli - drug effects | Pyrophosphatases - genetics | DNA Polymerase II - metabolism | DNA Breaks, Double-Stranded | DNA-Directed DNA Polymerase - genetics | Guanine - metabolism | Norfloxacin - pharmacology | Escherichia coli - metabolism | Ampicillin - pharmacology | Deoxyguanine Nucleotides - metabolism | DNA Polymerase beta - metabolism | DNA Polymerase I - genetics | DNA Polymerase II - genetics | DNA Polymerase beta - genetics | RNA, Bacterial - metabolism | DNA Glycosylases - metabolism | Oxidation-Reduction | DNA Glycosylases - genetics | Escherichia coli Proteins - metabolism | Hydroxyl Radical - metabolism | Microbial Viability | Kanamycin - pharmacology | Pyrophosphatases - metabolism | Escherichia coli - genetics | Models, Biological | Escherichia coli Proteins - genetics | Anti-Bacterial Agents - pharmacology | DNA-Directed DNA Polymerase - metabolism | DNA Polymerase I - metabolism | Physiological aspects | Oxidation-reduction reaction | Research | Health aspects | Guanine | Drug therapy | Index Medicus | Adjuvants
Journal Article
NATURE, ISSN 0028-0836, 06/2014, Volume 510, Issue 7504, pp. 293 - 293
Efficient duplication of the genome requires the concerted action of helicase and DNA polymerases at replication forks(1) to avoid stalling of the replication... 
SISTER-CHROMATID COHESION | MCM2-7 HELICASE | SYSTEM | COMPLEX | REPLICATION | PROTEIN | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | S PHASE | SACCHAROMYCES-CEREVISIAE | PROGRESSION | Minichromosome Maintenance Proteins - metabolism | Protein Multimerization | Molecular Sequence Data | Multienzyme Complexes - metabolism | Crystallography, X-Ray | Saccharomyces cerevisiae - ultrastructure | DNA Helicases - ultrastructure | DNA-Directed DNA Polymerase - chemistry | Minichromosome Maintenance Proteins - chemistry | Protein Subunits - metabolism | DNA-Binding Proteins - metabolism | Protein Structure, Quaternary | Conserved Sequence | Saccharomyces cerevisiae Proteins - ultrastructure | Amino Acid Sequence | DNA Helicases - chemistry | Catalytic Domain | Models, Molecular | DNA Replication | Nuclear Proteins - metabolism | DNA Polymerase I - chemistry | Microscopy, Electron | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Saccharomyces cerevisiae - chemistry | Amino Acid Motifs | Multienzyme Complexes - chemistry | DNA-Binding Proteins - ultrastructure | DNA Helicases - metabolism | DNA Polymerase I - ultrastructure | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein Subunits - chemistry | DNA-Directed DNA Polymerase - metabolism | DNA Polymerase I - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7484, pp. 564 - 568
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 12/2017, Volume 45, Issue 21, pp. e175 - e175
We describe a method for measuring the single-turnover incorporation kinetics of non-fluorescent native nucleotides by DNA polymerases. Time-lapse total... 
HIGH-FIDELITY | SITE | SPECIFICITY | MECHANISM | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | LABELED NUCLEOTIDES | KLENOW FRAGMENT | Time-Lapse Imaging - methods | DNA-Directed DNA Polymerase - metabolism | Kinetics | Nucleotides - metabolism | DNA Polymerase I - metabolism | Microscopy, Fluorescence | Index Medicus | Methods Online
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2017, Volume 65, Issue 1, pp. 131 - 141
Eukaryotic chromosomal DNA is faithfully replicated in a complex series of cell-cycle-regulated events that are incompletely understood. Here we report the... 
ORC | DNA replication | DNA polymerase | leading strand | McM2-7 | lagging strand | chromatin | replication origin | Okazaki fragment | YEAST | POLYMERASE-DELTA | IN-VITRO | ORIGIN | FORK | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | ALPHA | LAGGING-STRAND SYNTHESIS | SACCHAROMYCES-CEREVISIAE | EPSILON | CELL BIOLOGY | Chromatin - metabolism | DNA Polymerase III - genetics | DNA, Fungal - genetics | Saccharomyces cerevisiae - genetics | Humans | DNA Polymerase II - metabolism | Saccharomyces cerevisiae - metabolism | DNA, Fungal - biosynthesis | Proliferating Cell Nuclear Antigen - genetics | Time Factors | DNA Polymerase I - genetics | DNA Polymerase II - genetics | DNA Topoisomerases, Type II - metabolism | DNA Topoisomerases, Type I - metabolism | DNA Topoisomerases, Type I - genetics | Nucleosomes - metabolism | DNA Replication | Genotype | Nucleosomes - genetics | DNA - metabolism | Saccharomyces cerevisiae Proteins - genetics | DNA - genetics | Phenotype | Replication Origin | Saccharomyces cerevisiae Proteins - metabolism | DNA Topoisomerases, Type II - genetics | DNA Polymerase III - metabolism | Proliferating Cell Nuclear Antigen - metabolism | Chromatin - genetics | DNA Polymerase I - metabolism | Chromosome replication | Chromatin | Analysis | DNA | Genetic research | DNA polymerases | DNA synthesis | Molecular biology | College graduates | Index Medicus
Journal Article
Biochemistry, ISSN 0006-2960, 12/2013, Volume 52, Issue 48, pp. 8766 - 8776
Journal Article