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1. Full Text POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation
by Latrick, Chrysa M and Cech, Thomas R
The EMBO Journal, ISSN 0261-4189, 03/2010, Volume 29, Issue 5, pp. 924 - 933
Telomerase contributes to chromosome end replication by synthesizing repeats of telomeric DNA, and the telomeric DNA‐binding proteins protection of telomeres... 
POT1 | TPP1 | telomerase | translocation | processivity | Translocation | Processivity | Telomerase | COMPLEX | RNA | PROTECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | REVERSE-TRANSCRIPTASE | SHELTERIN | CELL BIOLOGY | LENGTH REGULATOR | DNA | ELONGATION | END-BINDING-PROTEIN | HUMAN POT1 | Serine Proteases - metabolism | Cell Line | Rabbits | Humans | DNA-Binding Proteins - metabolism | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism | Animals | Telomerase - genetics | Models, Biological | DNA Primers - metabolism | Telomerase - metabolism | Biological Transport - genetics | Biological Transport - physiology | Electrophoretic Mobility Shift Assay | Telomere-Binding Proteins - metabolism | Aminopeptidases - metabolism | Proteins | Enzymes | Molecular biology | Genomics | Deoxyribonucleic acid--DNA | Index Medicus
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2. Full Text Sensitive fluorescent detection of DNA methyltransferase using nicking endonuclease-mediated multiple primers-like rolling circle amplification
by Huang, Juan and Li, Xiao-Yu and Du, Yi-Chen and Zhang, Li-Na and Liu, Ke-Ke and Zhu, Li-Na and Kong, De-Ming
Biosensors and Bioelectronics, ISSN 0956-5663, 05/2017, Volume 91, pp. 417 - 423
Sensitive and reliable detection of DNA methyltransferase (MTase) is of great significance for both early tumor diagnosis and therapy. In this study, a simple,... 
Multiple primers | Inhibitor | Rolling circle amplification | Real-time | Methyltransferase | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | ISOTHERMAL DETECTION | ACTIVITY ASSAY | SELECTIVE RECOGNITION | NANOSCIENCE & NANOTECHNOLOGY | SIGNAL AMPLIFICATION | ADENINE METHYLATION | ELECTROCHEMICAL DETECTION | BIOPHYSICS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | G-QUADRUPLEX | PROBE | HYBRIDIZATION CHAIN-REACTION | RESTRICTION-ENDONUCLEASE | Spectrometry, Fluorescence - methods | Nucleic Acid Amplification Techniques - methods | DNA (Cytosine-5-)-Methyltransferase 1 | Humans | Enzyme Assays - methods | DNA - metabolism | Endonucleases - metabolism | DNA Primers - chemistry | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA-Cytosine Methylases - analysis | DNA - chemistry | DNA (Cytosine-5-)-Methyltransferases - analysis | MCF-7 Cells | HEK293 Cells | DNA Primers - metabolism | Biosensing Techniques - methods | G-Quadruplexes | HeLa Cells | DNA-Cytosine Methylases - metabolism | Genetic research | Nucleases | Methyltransferases | DNA | Usage | Index Medicus
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3. Full Text High-coverage ITS primers for the DNA-based identification of ascomycetes and basidiomycetes in environmental samples
by Toju, Hirokazu and Tanabe, Akifumi S and Yamamoto, Satoshi and Sato, Hirotoshi
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e40863 - e40863
The kingdom Fungi is estimated to include 1.5 million or more species, playing key roles as decomposers, mutualists, and parasites in every biome on the earth.... 
ENDOPHYTES | ECTOMYCORRHIZAL GENUS STROBILOMYCES | SPECIFICITY | MARKER | MULTIDISCIPLINARY SCIENCES | FUNGAL COMMUNITIES | BARCODE | DIVERSITY | REVEAL | ABUNDANCE | REGION | Temperature | DNA, Fungal - genetics | Computational Biology | Base Pair Mismatch | DNA, Intergenic - genetics | RNA, Ribosomal - genetics | Nucleic Acid Renaturation - genetics | Cell Nucleus - genetics | Environmental Microbiology | Plants - genetics | Base Sequence | Basidiomycota - classification | Ascomycota - genetics | Polymerase Chain Reaction | Basidiomycota - genetics | DNA Primers - metabolism | Ascomycota - classification | Mycological Typing Techniques | Surveys | Fungi | Databases | Bar codes | DNA | Nucleotide sequencing | Comparative analysis | DNA sequencing | Ecosystems | Taxonomy | Soil investigations | Science | Identification | Genomes | Parasites | Surveying | Data bases | Biological diversity | Gene sequencing | Primers | Spacer | Ecological monitoring | Deoxyribonucleic acid--DNA | Index Medicus | Deoxyribonucleic acid
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4. Full Text eDNA and specific primers for early detection of invasive species – A case study on the bivalve Rangia cuneata, currently spreading in Europe
by Ardura, Alba and Zaiko, Anastasija and Martinez, Jose L and Samulioviene, Aurelija and Semenova, Anna and Garcia-Vazquez, Eva
Marine Environmental Research, ISSN 0141-1136, 12/2015, Volume 112, Issue Pt B, pp. 48 - 55
Intense human activities facilitate the successful spread and establishment of non-indigenous aquatic organisms in marine and freshwater ecosystems. In some... 
Species-specific marker | Vistula Lagoon | Rangia cuneata | eDNA | Baltic Sea | Non-indigenous species | EDNA | CLIMATE-CHANGE | ENVIRONMENTAL SCIENCES | MODELS | DNA | MARINE & FRESHWATER BIOLOGY | TOXICOLOGY | IMPACTS | MARINE | RNA, Ribosomal, 16S - metabolism | Conservation of Natural Resources - methods | Species Specificity | Bivalvia - classification | Molecular Sequence Data | DNA Primers - genetics | Russia | Sequence Alignment | Animals | Base Sequence | Polymerase Chain Reaction | DNA Primers - metabolism | RNA, Ribosomal, 16S - genetics | Bivalvia - genetics | Bivalvia - metabolism | Introduced Species | Index Medicus
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5. Full Text Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID
by Cassandra B. Jabara and Corbin D. Jones and Jeffrey Roach and Jeffrey A. Anderson and Ronald Swanstrom
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 50, pp. 20166 - 20171
Viruses can create complex genetic populations within a host, and deep sequencing technologies allow extensive sampling of these populations. Limitations of... 
Polymerase chain reaction | Error rates | Complementary DNA | Genomes | Codons | Drug resistance | Genetic mutation | Sequencing | Population genetics | HIV 1 | Genetic diversity | Population dynamics | High throughput sequencing | HIV | genetic diversity | VARIANTS | LOW-FREQUENCY | MULTIDISCIPLINARY SCIENCES | REVERSE-TRANSCRIPTASE | population dynamics | SINGLE-DOSE NEVIRAPINE | TREATMENT-NAIVE | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | drug resistance | high throughput sequencing | ERROR-CORRECTION | DRUG-RESISTANCE MUTATIONS | PCR | Drug Resistance, Multiple, Viral - drug effects | Drug Resistance, Multiple, Viral - genetics | HIV-1 - drug effects | Humans | HIV Protease - genetics | Linkage Disequilibrium - genetics | Molecular Sequence Data | Templates, Genetic | Phylogeny | HIV-1 - genetics | Protease Inhibitors - pharmacology | RNA, Viral - genetics | Genetic Variation - drug effects | Genes, Viral - genetics | Base Sequence | Alleles | DNA Primers - metabolism | DNA, Complementary - biosynthesis | HIV-1 - enzymology | Codon - genetics | High-Throughput Nucleotide Sequencing - methods | Usage | Primers (Molecular genetics) | Genetic aspects | Nucleotide sequencing | HIV (Viruses) | Methods | DNA sequencing | Biological diversity | Gene amplification | Gene expression | Proteases | Human immunodeficiency virus--HIV | Drugs | Conserved sequence | Recombination | Gene frequency | Nucleotide sequence | Primers | Proteinase | Nucleotides | Sampling | pro gene | Index Medicus | Biological Sciences
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6. Full Text Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers
by Zhu, Bin and Wang, Longfei and Mitsunobu, Hitoshi and Lu, Xueling and Hernandez, Alfredo J and Yoshida-Takashima, Yukari and Nunoura, Takuro and Tabor, Stanley and Richardson, Charles C
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2017, Volume 114, Issue 2, pp. E2310 - E2318
A DNA polymerase is encoded by the deep-sea vent phage NrS-1. NrS-1 has a unique genome organization containing genes that are predicted to encode a helicase... 
Primase | Helicase | Prim-pol | SsDNA-binding protein | Nrs-1 | DOMAIN | RNA | MULTIDISCIPLINARY SCIENCES | PLASMID | prim-pol | ARCHAEO-EUKARYOTIC PRIMASE | primase | ORIGIN | NrS-1 | REPLICATION PROTEINS | ssDNA-binding protein | helicase | VIRUSES | INSIGHTS | Bacteriophages - chemistry | Viral Proteins - chemistry | DNA, Single-Stranded - metabolism | DNA, Viral - metabolism | Viral Proteins - genetics | DNA Replication | DNA Primers - genetics | DNA-Directed DNA Polymerase - chemistry | DNA-Binding Proteins - genetics | Viral Proteins - metabolism | DNA-Directed DNA Polymerase - genetics | DNA, Single-Stranded - genetics | DNA-Binding Proteins - metabolism | Bacteriophages - genetics | DNA Primers - metabolism | Protein Domains | Bacteriophages - enzymology | DNA-Directed DNA Polymerase - metabolism | DNA, Viral - genetics | DNA polymerases | Physiological aspects | Nucleotide sequencing | Methods | DNA sequencing | Proteins | DNA polymerase | Plasmids | Genes | Genomes | Zinc | Binding sites | Index Medicus | Biological Sciences | PNAS Plus | prim–pol
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7. Full Text Direct visualization of RNA-DNA primer removal from okazaki fragments provides support for flap cleavage and exonucleolytic pathways in eukaryotic cells
by Liu, Bochao and Hu, Jiazhi and Wang, Jingna and Kong, Daochun
Journal of Biological Chemistry, ISSN 0021-9258, 03/2017, Volume 292, Issue 12, pp. 4777 - 4788
During DNA replication in eukaryotic cells, short single stranded DNA segments known as Okazaki fragments are first synthesized on the lagging strand. The... 
POLYMERASE-EPSILON | YEAST | IN-VITRO | PROTEIN | NUCLEAR ANTIGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDONUCLEASE-1 | STALLED REPLICATION FORKS | MATURATION | SACCHAROMYCES-CEREVISIAE | NUCLEOTIDE EXCISION-REPAIR | DNA, Fungal - genetics | DNA - ultrastructure | DNA Primers - genetics | RNA - genetics | Schizosaccharomyces - genetics | DNA - analysis | Endodeoxyribonucleases - analysis | Endodeoxyribonucleases - metabolism | Schizosaccharomyces pombe Proteins - metabolism | DNA Primers - metabolism | Schizosaccharomyces pombe Proteins - analysis | DNA Primers - analysis | Flap Endonucleases - genetics | RNA - metabolism | DNA, Fungal - analysis | Schizosaccharomyces pombe Proteins - genetics | RNA - analysis | Signal Transduction | DNA Replication | DNA - metabolism | Flap Endonucleases - analysis | Flap Endonucleases - metabolism | DNA - genetics | Schizosaccharomyces - metabolism | Endodeoxyribonucleases - genetics | DNA, Fungal - metabolism | Mutation | Schizosaccharomyces - cytology | Index Medicus | deoxyribonuclease (DNase) | DNA structure | endonuclease | flap structures | Okazaki fragment processing | DNA and Chromosomes | DNA replication | Fen1 | Exo1 | DNA enzyme | Dna2
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8. Full Text Mitochondrial protein BmPAPI modulates the length of mature piRNAs
by Honda, Shozo and Kirino, Yoriko and Maragkakis, Manolis and Alexiou, Panagiotis and Ohtaki, Akashi and Murali, Ramachandran and Mourelatos, Zissimos and Kirino, Yohei
RNA, ISSN 1355-8382, 10/2013, Volume 19, Issue 10, pp. 1405 - 1418
PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposons in animal germlines. The molecular... 
BmPAPI | TUDOR | Mitochondria | PiRNA | PIWI | Arginine methylation | NUAGE FORMATION | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBCELLULAR-LOCALIZATION | 3' TERMINI | SPLICEOSOMAL SM PROTEINS | DROSOPHILA | PIWI-INTERACTING RNAS | TUDOR-DOMAIN | ROYAL FAMILY | arginine methylation | STRUCTURAL BASIS | piRNA | Surface Plasmon Resonance | RNA, Small Interfering - genetics | Immunoprecipitation | RNA-Induced Silencing Complex - genetics | DNA Primers - genetics | Mitochondrial Proteins - genetics | DNA Primers - chemistry | Drosophila Proteins - metabolism | Ovary - cytology | Drosophila melanogaster - genetics | Arginine - analogs & derivatives | Drosophila melanogaster - metabolism | RNA, Small Interfering - chemistry | Bombyx - metabolism | Mitochondria - genetics | Membrane Transport Proteins - genetics | Mitochondrial Proteins - metabolism | DNA Primers - metabolism | Female | Membrane Transport Proteins - metabolism | Real-Time Polymerase Chain Reaction | Ovary - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Argonaute Proteins - metabolism | Argonaute Proteins - genetics | RNA, Messenger - genetics | Mitochondria - metabolism | Recombinant Proteins - genetics | Bombyx - genetics | Germ Cells | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Carrier Proteins - genetics | Blotting, Northern | Animals | Carrier Proteins - metabolism | Fluorescent Antibody Technique | RNA-Induced Silencing Complex - metabolism | Drosophila Proteins - genetics | Arginine - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Genomes
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9. Full Text Continued primer synthesis at stalled replication forks contributes to checkpoint activation
by Christopher Van and Shan Yan and W. Matthew Michael and Shou Waga and Karlene A. Cimprich
The Journal of Cell Biology, ISSN 0021-9525, 4/2010, Volume 189, Issue 2, pp. 233 - 246
Stalled replication forks activate and are stabilized by the ATR (ataxia-telangiectasia mutated and Rad3 related)-mediated checkpoint, but ultimately, they... 
Chromatin | Phosphorylation | DNA replication | Spermatozoa | Gels | Plasmids | DNA | DNA damage | Cell cycle | Eggs | DAMAGE CHECKPOINT | XENOPUS EGG EXTRACTS | IN-VITRO | MEDIATED RECRUITMENT | MULTIPLE MECHANISMS | DNA-POLYMERASE-ALPHA | UV-INDUCED LESION | CELL-FREE SYSTEM | SINGLE-STRANDED-DNA | S-PHASE CHECKPOINT | CELL BIOLOGY | Protein Kinases - metabolism | Aphidicolin - metabolism | Chromatin - metabolism | Protein Kinases - genetics | Xenopus Proteins - genetics | Male | DNA Primers - genetics | DNA, Single-Stranded - genetics | Cell Cycle Proteins - genetics | DNA Primers - metabolism | Female | Xenopus laevis - genetics | DNA Polymerase I - genetics | Protein-Serine-Threonine Kinases - metabolism | Enzyme Inhibitors - metabolism | DNA, Single-Stranded - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | DNA Replication | Ataxia Telangiectasia Mutated Proteins | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Xenopus laevis - metabolism | Checkpoint Kinase 1 | Xenopus Proteins - metabolism | DNA Polymerase I - metabolism | Observations | Frogs | Antigens | Eukaryotes | Cellular biology | Protein synthesis | Deoxyribonucleic acid--DNA | Cells | Index Medicus
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10. Full Text Single-stranded DNA library preparation from highly degraded DNA using T4 DNA ligase
by Gansauge, Marie-Theres and Gerber, Tobias and Glocke, Isabelle and Korlević, Petra and Lippik, Laurin and Nagel, Sarah and Riehl, Lara Maria and Schmidt, Anna and Meyer, Matthias
Nucleic Acids Research, ISSN 0305-1048, 2017, Volume 45, Issue 10, pp. e79 - e79
DNA library preparation for high-throughput sequencing of genomic DNA usually involves ligation of adapters to double-stranded DNA fragments. However, for... 
ORIGIN | GENOME SEQUENCE | AMPLIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANCIENT DNA | LIGATION | NEANDERTHAL | IN-SITU | DAMAGE | CELL-FREE DNA | Oligonucleotides - genetics | Nucleic Acid Hybridization | Bone and Bones - chemistry | Gene Library | DNA Ligases - genetics | DNA, Single-Stranded - metabolism | Humans | DNA - metabolism | DNA Primers - chemistry | Sequence Analysis, DNA | Liver - chemistry | DNA Ligases - metabolism | Fossils | DNA - genetics | DNA, Single-Stranded - genetics | Oligonucleotides - metabolism | Animals | Swine | Polymerase Chain Reaction | DNA Primers - metabolism | Horses | High-Throughput Nucleotide Sequencing | Index Medicus | Methods Online
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11. Full Text Discrimination Between 8‐Oxo‐2′‐Deoxyguanosine and 2′‐Deoxyguanosine in DNA by the Single Nucleotide Primer Extension Reaction with Adap Triphosphate
by Taniguchi, Yosuke and Kikukawa, Yoshiya and Sasaki, Shigeki
Angewandte Chemie International Edition, ISSN 1433-7851, 04/2015, Volume 54, Issue 17, pp. 5147 - 5151
The adenosine derivative of 2‐oxo‐1,3‐diazaphenoxazine (Adap) exhibits a superb ability to recognize and form base pairs with 8‐oxo‐2′‐deoxyguanosine... 
oxidation | enzymes | nucleotides | DNA damage | sequence determination | SITE | OXIDATIVE DAMAGE | CHEMISTRY, MULTIDISCIPLINARY | LESIONS | 8-OXOGUANINE | STRANDED-DNA | SEQUENCE | GUANINE | 8-OXO-7,8-DIHYDRO-2'-DEOXYGUANOSINE | FLUORESCENT-PROBE | BASE ANALOGS | Fluorescent Dyes - chemistry | Oxidation-Reduction | Humans | DNA - metabolism | Deoxyguanosine - analysis | Nucleic Acid Amplification Techniques | Polyphosphates - chemical synthesis | Polyphosphates - metabolism | Hydrogen Peroxide - chemistry | Base Pairing | DNA - analysis | DNA Primers - metabolism | DNA Damage | HeLa Cells | DNA Polymerase I - metabolism | Deoxyguanosine - analogs & derivatives | Telomere - genetics | Discrimination | Mutation | DNA repair | Deoxyribonucleic acid--DNA | Index Medicus | Human | Deoxyribonucleic acid | Strands | Genomes | Derivatives | Nucleotides | Gene sequencing | Fragmentation
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12. Full Text Monitoring the Retention of Human Proliferating Cell Nuclear Antigen at Primer/Template Junctions by Proteins That Bind Single-Stranded DNA
by Hedglin, Mark and Aitha, Mahesh and Benkovic, Stephen J
Biochemistry, ISSN 0006-2960, 07/2017, Volume 56, Issue 27, pp. 3415 - 3421
In humans, proliferating cell nuclear antigen (PCNA) sliding clamps encircling DNA coordinate various aspects of DNA metabolism throughout the cell cycle. A... 
COMPLEX | RPA | PCNA | FORK | SLIDING CLAMPS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | KINASE | DIFFUSION | REPLICATION FACTOR-C | BETA | Carbocyanines - chemistry | Humans | Molecular Conformation | DNA Primers - chemistry | Avidin - metabolism | Biotin - chemistry | DNA-Binding Proteins - metabolism | Proliferating Cell Nuclear Antigen - genetics | Replication Protein A - chemistry | Replication Protein A - genetics | DNA Primers - metabolism | Fluorescence Resonance Energy Transfer | Avidin - chemistry | Biotin - metabolism | Protein Interaction Domains and Motifs | Protein Stability | Binding Sites | Peptide Fragments - genetics | Recombinant Proteins - metabolism | Fluorescent Dyes - chemistry | Peptide Fragments - metabolism | DNA, Single-Stranded - metabolism | Models, Molecular | Recombinant Proteins - chemistry | DNA Replication | Escherichia coli Proteins - metabolism | Replication Protein A - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | DNA, Single-Stranded - chemistry | Proliferating Cell Nuclear Antigen - chemistry | Peptide Fragments - chemistry | Escherichia coli Proteins - genetics | Mutation | Escherichia coli Proteins - chemistry | Proliferating Cell Nuclear Antigen - metabolism | Microscopy, Fluorescence | DNA binding proteins | Research | Escherichia coli | Proliferating cell nuclear antigen | Index Medicus
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