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Nucleic Acids Research, ISSN 0305-1048, 09/2019, Volume 47, Issue 15, pp. 8163 - 8179
Abstract Type II topoisomerases catalyze essential DNA transactions and are proven drug targets. Drug discrimination by prokaryotic and eukaryotic... 
DNA TOPOISOMERASE | IN-VITRO | STRUCTURAL BASIS | ATPASE DOMAIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTANTS RESISTANT | DRUG-RESISTANCE | CONFER RESISTANCE | STRAND BREAKS | BETA | Nucleic Acid Enzymes
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2003, Volume 100, Issue 17, pp. 9820 - 9825
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2003, Volume 100, Issue 17, p. 9820
  Type-II topoisomerases are responsible for untangling DNA during replication by removing supercoiled and interlinked DNA structures. Using a single-molecule... 
Molecules | Eukaryotes | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Russian Journal of Bioorganic Chemistry, ISSN 1068-1620, 05/2003, Volume 29, Issue 3, pp. 249 - 261
Data on the interaction of DNA type I topoisomerases from the murine and human placenta cells with specific and nonspecific oligonucleotides of various... 
DNA topoisomerase I from murine and human placenta | mechanism of interaction with the specific DNA | Chemistry | Organic Chemistry | Mechanism of interaction with the specific DNA | CHEMISTRY, ORGANIC | HIGH-AFFINITY INTERACTION | BIOCHEMISTRY & MOLECULAR BIOLOGY
Journal Article
Journal Article
Bioorganicheskaia khimiia, ISSN 0132-3423, 05/2003, Volume 29, Issue 3, p. 277
Data on the interaction of DNA type I topoisomerases from the murine and human placenta cells with specific and nonspecific oligonucleotides of various... 
Oligonucleotides - chemistry | DNA Topoisomerases, Type I - metabolism | Humans | DNA Topoisomerases, Type I - chemistry | Models, Molecular | Substrate Specificity | DNA - metabolism | Thermodynamics | DNA - chemistry | Oligonucleotides - metabolism | Animals | Protein Conformation | Mice | Kinetics
Journal Article
Pathology, ISSN 0031-3025, 04/2004, Volume 36, Issue 2, pp. 139 - 144
To gain a better insight into the biological behaviour of subependymal giant cell astrocytoma (SEGA), tumour suppressor gene protein expression and various... 
Rb protein | MIB-1 LI | PCNA LI | Topo II LI | SEGA | Subependymal giant cell astrocytoma | tuberous sclerosis | p53 protein | brain tumours | Tuberous sclerosis | Brain tumours | GLIOMAS | subependymal giant cell astrocytoma | DNA TOPOISOMERASE-II | NUCLEAR ANTIGEN | PATHOLOGY | BRAIN-TUMORS | KI-67 | PROGRESSION | IMMUNOHISTOCHEMISTRY | Glioma, Subependymal - surgery | Mitosis | Humans | Cerebral Ventricle Neoplasms - surgery | DNA Topoisomerases, Type II - analysis | Child, Preschool | Male | Tomography, X-Ray Computed | Tumor Suppressor Protein p53 - genetics | Biomarkers, Tumor - metabolism | Adult | Female | Child | DNA-Binding Proteins | Glioma, Subependymal - pathology | Antigens, Neoplasm | Giant Cells - metabolism | Retinoblastoma Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Cerebral Ventricle Neoplasms - metabolism | Treatment Outcome | Proliferating Cell Nuclear Antigen - analysis | Cerebral Ventriculography | Ki-67 Antigen - analysis | Glioma, Subependymal - metabolism | Retinoblastoma Protein - genetics | Adolescent | Cerebral Ventricle Neoplasms - pathology | Giant Cells - pathology | Cerebral Ventricle Neoplasms, surgery | Tumor Markers, Biological, metabolism | Cerebral Ventricle Neoplasms, metabolism | Protein p53, genetics | Ki-67 Antigen, analysis | Giant Cells, pathology | Cerebral Ventricle Neoplasms, pathology | Protein p53, metabolism | Human | DNA Topoisomerases, Type II, Eukaryotic, analysis | Glioma, Subependymal, surgery | Glioma, Subependymal, pathology | Retinoblastoma Protein, genetics | Giant Cells, metabolism | Glioma, Subependymal, metabolism | Proliferating Cell Nuclear Antigen, analysis | Retinoblastoma Protein, metabolism
Journal Article
Journal Article
Pathology, ISSN 0031-3025, 08/2003, Volume 35, Issue 4, pp. 315 - 318
Journal Article
Breast cancer mortality in Sweden is now in decline, thanks to early detection and the wide use of adjuvant endocrine therapy and chemotherapy. While hormone... 
TOP2A | anthracycline | in vitro | Onkologi | predictive | Oncology | breast cancer | topoisomerase | HER2 | cyclin A | chemotherapy
Dissertation
Journal Article
19.