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Nature Immunology, ISSN 1529-2908, 05/2010, Volume 11, Issue 5, pp. 395 - 402
Inflammasomes regulate the activity of caspase-1 and the maturation of interleukin 1. (IL-1.) and IL-18. AIM2 has been shown to bind DNA and engage the... 
RECOGNITION | TOLL-LIKE RECEPTOR | INDUCIBLE GENES | INNATE IMMUNE-RESPONSE | INFECTION | VACCINIA VIRUS | IMMUNOLOGY | MURINE CYTOMEGALOVIRUS | FRANCISELLA-TULARENSIS | CASPASE-1 ACTIVATION | FAMILY | Tularemia - metabolism | Cytoskeletal Proteins - genetics | Humans | Tularemia - genetics | Caspase 1 - metabolism | Multiprotein Complexes - genetics | Multiprotein Complexes - metabolism | Lymphocyte Activation - genetics | Transcription Factors - immunology | Cytokines - genetics | Macrophages - microbiology | DNA-Binding Proteins | DNA Viruses - pathogenicity | Macrophages - pathology | Killer Cells, Natural - virology | Listeriosis - genetics | Signal Transduction - genetics | DNA Virus Infections - genetics | Viral Load - immunology | Mice, Knockout | Macrophages - metabolism | DNA Virus Infections - immunology | Mice | Killer Cells, Natural - metabolism | Multiprotein Complexes - immunology | DNA Virus Infections - metabolism | Caspase 1 - immunology | Killer Cells, Natural - pathology | Signal Transduction - immunology | Macrophages - virology | Listeriosis - immunology | Tularemia - immunology | Killer Cells, Natural - immunology | Nuclear Proteins - genetics | Macrophages - immunology | Cytokines - immunology | Killer Cells, Natural - microbiology | Cell Line | Francisella tularensis - immunology | Listeriosis - metabolism | Cytokines - metabolism | DNA - immunology | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Transcription Factors - genetics | Immunity, Innate | Nuclear Proteins - immunology | Viral Load - genetics | DNA Viruses - immunology | Transcription Factors - metabolism | Animals | Apoptosis Regulatory Proteins | Caspase 1 - genetics | DNA Viruses - growth & development | CARD Signaling Adaptor Proteins | Francisella tularensis - pathogenicity | Bacterial infections | Immune response | Cytomegalovirus infections | Research | DNA viruses | Health aspects | Risk factors | Index Medicus
Journal Article
Nature Communications [E], ISSN 2041-1723, 02/2016, Volume 7, Issue 1, pp. 10680 - 10680
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2015, Volume 136, Issue 1, pp. 98 - 107
Journal Article
British Journal of Cancer, ISSN 0007-0920, 08/2016, Volume 115, Issue 4, pp. 497 - 504
Background: Although similar to 20% of human cancers are caused by microorganisms, only suspicion exists for a microbial cause of lung cancer. Potential... 
non-small cell lung cancer | retrovirus | DETECTION MICROARRAY | NSCLC | HUMAN-PAPILLOMAVIRUS | virus | MICROBIAL DETECTION | HPV | microarray | carcinogenesis | ONCOLOGY | human papillomavirus | SARCOMA | INFECTION | SAMPLES | HEPATITIS-B | ASSOCIATION | CARCINOMA | Retroviridae Infections - virology | Retroviridae Infections - complications | Tumor Virus Infections - virology | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - virology | Humans | Lung Neoplasms - metabolism | Middle Aged | DNA, Viral - analysis | Male | Papillomaviridae - genetics | Lung - virology | Receptor, Epidermal Growth Factor - metabolism | Adenocarcinoma - metabolism | Retroviridae - genetics | Polymerase Chain Reaction | Aged, 80 and over | Female | Papillomavirus Infections - virology | Lung - metabolism | Carcinoma, Non-Small-Cell Lung - virology | Papillomavirus Infections - complications | Tumor Virus Infections - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Genotype | Retroviridae Infections - metabolism | Lung Neoplasms - virology | Adenocarcinoma - complications | Adenocarcinoma - virology | Lung Neoplasms - complications | Tumor Virus Infections - complications | Carcinoma, Non-Small-Cell Lung - complications | Papillomavirus Infections - metabolism | Carcinoma, Squamous Cell - complications | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Oncogenic Viruses - genetics | Aged | Index Medicus | Virus | Retrovirus | Human papillomavirus | BASIC BIOLOGICAL SCIENCES | Non-small cell lung cancer | Microarray | Carcinogenesis | Molecular Diagnostics
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2011, Volume 108, Issue 36, pp. 14902 - 14907
Epstein-Barr virus nuclear antigen 2 (EBNA2) regulation of transcription through the cell transcription factor RBPJ is essential for resting B-lymphocyte (RBL)... 
T lymphocytes | Up regulation | Chromatin | B lymphocytes | DNA | Nucleosomes | Gene expression regulation | Epstein Barr virus infections | Human herpesvirus 4 | Binding sites | Development | Lymphoma | Leukemia | Notch | leukemia | development | SIGNAL-BINDING-PROTEIN | CIS-ELEMENT | MULTIDISCIPLINARY SCIENCES | lymphoma | C-MYC | NUCLEAR ANTIGEN-2 | FATE | GENOME | LONG-RANGE INTERACTION | GENE | PROMOTER | J-KAPPA | Cell Proliferation | Herpesvirus 4, Human - genetics | Proto-Oncogene Proteins c-ets - genetics | Genome, Viral - genetics | Humans | Transcription Factor RelA - genetics | Viral Proteins - metabolism | Trans-Activators - genetics | B-Lymphocytes - virology | Epstein-Barr Virus Infections - genetics | Core Binding Factor alpha Subunits - metabolism | Transcription, Genetic | Proto-Oncogene Proteins c-ets - metabolism | Epstein-Barr Virus Nuclear Antigens - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | B-Lymphocytes - metabolism | Proto-Oncogene Proteins - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Epstein-Barr Virus Nuclear Antigens - genetics | Response Elements | Nucleosomes - metabolism | Viral Proteins - genetics | Nucleosomes - genetics | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Core Binding Factor alpha Subunits - genetics | Transcription Factor RelA - metabolism | Cell Line, Tumor | Trans-Activators - metabolism | Proto-Oncogene Proteins c-myc - genetics | Herpesvirus 4, Human - metabolism | Epstein-Barr Virus Infections - metabolism | Physiological aspects | Transcription factors | Epstein-Barr virus | Genetic aspects | Lymphocytes | Health aspects | Cell growth | Deoxyribonucleic acid--DNA | Index Medicus | ETS protein | Lymphoblasts | Introns | Data processing | Genomes | Myc protein | Promoters | Early B-cell factor | Infection | Enhancers | PU.1 protein | Lymphocytes B | Fluorescence in situ hybridization | RelA protein | Conformation | Biological Sciences
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2012, Volume 122, Issue 12, pp. 4645 - 4653
A human polyomavirus was recently discovered in Merkel cell carcinoma (MCC) specimens. The Merkel cell polyomavirus (MCPyV) genome undergoes clonal integration... 
MEDICINE, RESEARCH & EXPERIMENTAL | RETINOBLASTOMA PROTEIN | GENE | C-KIT | INFECTION | MUTATIONS | LARGE T-ANTIGEN | EXPRESSION | TUMORS | NEUROENDOCRINE CARCINOMAS | P53 | Immunohistochemistry | Tumor Virus Infections - virology | Humans | Middle Aged | Tumor Virus Infections - diagnosis | Male | Carcinoma, Merkel Cell - diagnosis | Polyomavirus Infections - metabolism | Molecular Diagnostic Techniques | DNA Mutational Analysis | Aged, 80 and over | Female | Genes, Tumor Suppressor | Real-Time Polymerase Chain Reaction | Oncogenes | Tumor Virus Infections - metabolism | Antigens, Polyomavirus Transforming - metabolism | Merkel cell polyomavirus - metabolism | Genotype | Gene Dosage | Merkel cell polyomavirus - immunology | Polyomavirus Infections - diagnosis | Antigens, Polyomavirus Transforming - immunology | Polyomavirus Infections - virology | Carcinoma, Merkel Cell - metabolism | Cell Line, Tumor | Merkel cell polyomavirus - genetics | Antibodies, Viral - immunology | Carcinoma, Merkel Cell - virology | Aged | Antigens | Care and treatment | Gene mutations | Merkel cell carcinoma | Polyoma virus | Genetic aspects | Diagnosis | Properties | Identification and classification | Index Medicus | Abridged Index Medicus | Polymerase chain reaction | Integration | Carcinoma | Primers | Monoclonal antibodies | Genomes | Chromosomes | p53 protein | Amino acid substitution | Tumors
Journal Article
Cancer Research, ISSN 0008-5472, 08/2013, Volume 73, Issue 16, pp. 4982 - 4987
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2011, Volume 17, Issue 14, pp. 4806 - 4813
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2012, Volume 109, Issue 50, pp. E3473 - E3482